-
1
-
-
0036178134
-
A critical review of the fluoroquinolones: Focus on respiratory infections
-
G.G. Zhanel, K. Ennis, and L. Vercaigne A critical review of the fluoroquinolones: focus on respiratory infections Drugs 62 2002 13 59
-
(2002)
Drugs
, vol.62
, pp. 13-59
-
-
Zhanel, G.G.1
Ennis, K.2
Vercaigne, L.3
-
2
-
-
0037447017
-
Factors associated with relative rates of antimicrobial resistance among Streptococcus pneumoniae in the United States: Results from the TRUST Surveillance Program (1998-2002)
-
J.A. Karlowsky, C. Thornsberry, M.E. Jones, A.T. Evangelista, I.A. Critchley, and D.F. Sahm Factors associated with relative rates of antimicrobial resistance among Streptococcus pneumoniae in the United States: results from the TRUST Surveillance Program (1998-2002) Clin Infect Dis 36 2003 963 970
-
(2003)
Clin Infect Dis
, vol.36
, pp. 963-970
-
-
Karlowsky, J.A.1
Thornsberry, C.2
Jones, M.E.3
Evangelista, A.T.4
Critchley, I.A.5
Sahm, D.F.6
-
3
-
-
0346025671
-
Antimicrobial susceptibility among community-acquired respiratory tract pathogens in the USA: Data from PROTEKT US 2000-2001
-
G.V. Doern, and S.D. Brown Antimicrobial susceptibility among community-acquired respiratory tract pathogens in the USA: data from PROTEKT US 2000-2001 J Infect 48 2004 56 65
-
(2004)
J Infect
, vol.48
, pp. 56-65
-
-
Doern, G.V.1
Brown, S.D.2
-
4
-
-
0346725836
-
The activity of levofloxacin and other antimicrobials against clinical isolates of Streptococcus pneumoniae collected worldwide during 1999-2002
-
M.E. Jones, R.S. Blosser-Middleton, C. Thornsberry, J.A. Karlowsky, and D.F. Sahm The activity of levofloxacin and other antimicrobials against clinical isolates of Streptococcus pneumoniae collected worldwide during 1999-2002 Diagn Microbiol Infect Dis 47 2003 579 586
-
(2003)
Diagn Microbiol Infect Dis
, vol.47
, pp. 579-586
-
-
Jones, M.E.1
Blosser-Middleton, R.S.2
Thornsberry, C.3
Karlowsky, J.A.4
Sahm, D.F.5
-
5
-
-
0037453976
-
Antibiotic resistance among gram-negative bacilli in US intensive care units: Implications for fluoroquinolone use
-
M.M. Neuhauser, R.A. Weinstein, R. Rydman, L.H. Danziger, G. Karam, and J.P. Quinn Antibiotic resistance among gram-negative bacilli in US intensive care units: implications for fluoroquinolone use JAMA 289 2003 885 888
-
(2003)
JAMA
, vol.289
, pp. 885-888
-
-
Neuhauser, M.M.1
Weinstein, R.A.2
Rydman, R.3
Danziger, L.H.4
Karam, G.5
Quinn, J.P.6
-
6
-
-
0036917732
-
National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 to June 2002. Issued August 2002
-
NNIS System. National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 to June 2002. Issued August 2002. Am J Infect Control 2002;30:458-75.
-
(2002)
Am J Infect Control
, vol.30
, pp. 458-475
-
-
-
7
-
-
0034035397
-
Efflux and target mutations as quinolone resistance mechanisms in clinical isolates of Streptococcus pneumoniae
-
J. Broskey, K. Coleman, and M.N. Gwynn Efflux and target mutations as quinolone resistance mechanisms in clinical isolates of Streptococcus pneumoniae J Antimicrob Chemother 45 2000 95 99
-
(2000)
J Antimicrob Chemother
, vol.45
, pp. 95-99
-
-
Broskey, J.1
Coleman, K.2
Gwynn, M.N.3
-
8
-
-
0037257321
-
The importance of efflux pumps in bacterial antibiotic resistance
-
M.A. Webber, and L.J. Piddock The importance of efflux pumps in bacterial antibiotic resistance J Antimicrob Chemother 51 2003 9 11
-
(2003)
J Antimicrob Chemother
, vol.51
, pp. 9-11
-
-
Webber, M.A.1
Piddock, L.J.2
-
9
-
-
0345515642
-
Active efflux of tetracycline encoded by four genetically different tetracycline resistance determinants in Escherichia coli
-
L. McMurry, R.E. Petrucci Jr., and S.B. Levy Active efflux of tetracycline encoded by four genetically different tetracycline resistance determinants in Escherichia coli Proc. Natl. Acad. Sci. U.S.A. 77 1980 3974 3977
-
(1980)
Proc. Natl. Acad. Sci. U.S.A.
, vol.77
, pp. 3974-3977
-
-
McMurry, L.1
Petrucci Jr., R.E.2
Levy, S.B.3
-
10
-
-
0019153447
-
Plasmid-mediated tetracycline resistance in Escherichia coli involves increased efflux of the antibiotic
-
P.R. Ball, S.W. Shales, and I. Chopra Plasmid-mediated tetracycline resistance in Escherichia coli involves increased efflux of the antibiotic Biochem Biophys Res Commun 93 1980 74 81
-
(1980)
Biochem Biophys Res Commun
, vol.93
, pp. 74-81
-
-
Ball, P.R.1
Shales, S.W.2
Chopra, I.3
-
11
-
-
0036174176
-
Accumulation of 10 fluoroquinolones by wild-type or efflux mutant Streptococcus pneumoniae
-
L.J. Piddock, and M.M. Johnson Accumulation of 10 fluoroquinolones by wild-type or efflux mutant Streptococcus pneumoniae Antimicrob Agents Chemother 46 2002 813 820
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 813-820
-
-
Piddock, L.J.1
Johnson, M.M.2
-
12
-
-
0032778126
-
Activity of gemifloxacin against penicillin- and ciprofloxacin-resistant Streptococcus pneumoniae displaying topoisomerase- and efflux-mediated resistance mechanisms
-
V.J. Heaton, C.E. Goldsmith, J.E. Ambler, and L.M. Fisher Activity of gemifloxacin against penicillin- and ciprofloxacin-resistant Streptococcus pneumoniae displaying topoisomerase- and efflux-mediated resistance mechanisms Antimicrob Agents Chemother 43 1999 2998 3000
-
(1999)
Antimicrob Agents Chemother
, vol.43
, pp. 2998-3000
-
-
Heaton, V.J.1
Goldsmith, C.E.2
Ambler, J.E.3
Fisher, L.M.4
-
13
-
-
0036668109
-
Pharmacodynamic characterization of efflux and topoisomerase IV-mediated fluoroquinolone resistance in Streptococcus pneumoniae
-
K.J. Madaras-Kelly, C. Daniels, M. Hegbloom, and M. Thompson Pharmacodynamic characterization of efflux and topoisomerase IV-mediated fluoroquinolone resistance in Streptococcus pneumoniae J Antimicrob Chemother 50 2002 211 218
-
(2002)
J Antimicrob Chemother
, vol.50
, pp. 211-218
-
-
Madaras-Kelly, K.J.1
Daniels, C.2
Hegbloom, M.3
Thompson, M.4
-
14
-
-
0030770318
-
The effect of reserpine, an inhibitor of multidrug efflux pumps, on the in-vitro susceptibilities of fluoroquinolone-resistant strains of Streptococcus pneumoniae to norfloxacin
-
N.P. Brenwald, M.J. Gill, and R. Wise The effect of reserpine, an inhibitor of multidrug efflux pumps, on the in-vitro susceptibilities of fluoroquinolone-resistant strains of Streptococcus pneumoniae to norfloxacin J Antimicrob Chemother 40 1997 458 460
-
(1997)
J Antimicrob Chemother
, vol.40
, pp. 458-460
-
-
Brenwald, N.P.1
Gill, M.J.2
Wise, R.3
-
15
-
-
0031948133
-
Antibiotic resistance caused by gram-negative multidrug efflux pumps
-
H. Nikaido Antibiotic resistance caused by gram-negative multidrug efflux pumps Clin Infect Dis 27 1998 S32 S41
-
(1998)
Clin Infect Dis
, vol.27
-
-
Nikaido, H.1
-
16
-
-
0038381761
-
The role of multidrug efflux pumps in the antibiotic resistance of Pseudomonas aeruginosa and other Gram-negative bacteria
-
J.R. Aeschlimann The role of multidrug efflux pumps in the antibiotic resistance of Pseudomonas aeruginosa and other Gram-negative bacteria Pharmacotherapy 23 2003 916 924
-
(2003)
Pharmacotherapy
, vol.23
, pp. 916-924
-
-
Aeschlimann, J.R.1
-
18
-
-
0034458756
-
Macrolide and fluoroquinolone (levofloxacin) resistances among Streptococcus pneumoniae strains: Significant trends from the SENTRY antimicrobial surveillance program (North America, 1997-1999)
-
R.N. Jones, and M.A. Pfaller Macrolide and fluoroquinolone (levofloxacin) resistances among Streptococcus pneumoniae strains: significant trends from the SENTRY antimicrobial surveillance program (North America, 1997-1999) J Clin Microbiol 38 2000 4298 4299
-
(2000)
J Clin Microbiol
, vol.38
, pp. 4298-4299
-
-
Jones, R.N.1
Pfaller, M.A.2
-
19
-
-
0038441345
-
Antimicrobial resistance in respiratory tract Streptococcus pneumoniae isolates: Results of the Canadian Respiratory Organism Susceptibility Study, 1997 to 2002
-
G.G. Zhanel, L. Palatnick, K.A. Nichol, T. Bellyou, D.E. Low, and D.J. Hoban Antimicrobial resistance in respiratory tract Streptococcus pneumoniae isolates: results of the Canadian Respiratory Organism Susceptibility Study, 1997 to 2002 Antimicrob Agents Chemother 47 2003 1867 1874
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 1867-1874
-
-
Zhanel, G.G.1
Palatnick, L.2
Nichol, K.A.3
Bellyou, T.4
Low, D.E.5
Hoban, D.J.6
-
20
-
-
0036136859
-
Prevalence of single mutations in topoisomerase type II genes among levofloxacin-susceptible clinical strains of Streptococcus pneumoniae isolated in the United States in 1992 to 1996 and 1999 to 2000
-
T.A. Davies, A. Evangelista, S. Pfleger, K. Bush, D.F. Sahm, and R. Goldschmidt Prevalence of single mutations in topoisomerase type II genes among levofloxacin-susceptible clinical strains of Streptococcus pneumoniae isolated in the United States in 1992 to 1996 and 1999 to 2000 Antimicrob Agents Chemother 46 2002 119 124
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 119-124
-
-
Davies, T.A.1
Evangelista, A.2
Pfleger, S.3
Bush, K.4
Sahm, D.F.5
Goldschmidt, R.6
-
21
-
-
0037308639
-
Molecular characterization of fluoroquinolone resistant Streptococcus pneumoniae clinical isolates obtained from across Canada
-
G.G. Zhanel, A. Walkty, K. Nichol, H. Smith, A. Noreddin, and D.J. Hoban Molecular characterization of fluoroquinolone resistant Streptococcus pneumoniae clinical isolates obtained from across Canada Diagn Microbiol Infect Dis 45 2003 63 67
-
(2003)
Diagn Microbiol Infect Dis
, vol.45
, pp. 63-67
-
-
Zhanel, G.G.1
Walkty, A.2
Nichol, K.3
Smith, H.4
Noreddin, A.5
Hoban, D.J.6
-
22
-
-
0032907704
-
Identification of an efflux pump gene, pmrA, associated with fluoroquinolone resistance in Streptococcus pneumoniae
-
M.J. Gill, N.P. Brenwald, and R. Wise Identification of an efflux pump gene, pmrA, associated with fluoroquinolone resistance in Streptococcus pneumoniae Antimicrob Agents Chemother 43 1999 187 189
-
(1999)
Antimicrob Agents Chemother
, vol.43
, pp. 187-189
-
-
Gill, M.J.1
Brenwald, N.P.2
Wise, R.3
-
23
-
-
0035919670
-
Complete genome sequence of a virulent isolate of Streptococcus pneumoniae
-
H. Tettelin, K.E. Nelson, and I.T. Paulsen Complete genome sequence of a virulent isolate of Streptococcus pneumoniae Science 293 5529 2001 498 506
-
(2001)
Science
, vol.293
, Issue.5529
, pp. 498-506
-
-
Tettelin, H.1
Nelson, K.E.2
Paulsen, I.T.3
-
24
-
-
0038076278
-
Evidence for efflux pumps, other than PmrA, associated with fluoroquinolone resistance in Streptococcus pneumoniae
-
N.P. Brenwald, P. Appelbaum, T. Davies, and M.J. Gill Evidence for efflux pumps, other than PmrA, associated with fluoroquinolone resistance in Streptococcus pneumoniae Clin Microbiol Infect 9 2003 140 143
-
(2003)
Clin Microbiol Infect
, vol.9
, pp. 140-143
-
-
Brenwald, N.P.1
Appelbaum, P.2
Davies, T.3
Gill, M.J.4
-
25
-
-
0031927418
-
Prevalence of a putative efflux mechanism among fluoroquinolone-resistant clinical isolates of Streptococcus pneumoniae
-
N.P. Brenwald, M.J. Gill, and R. Wise Prevalence of a putative efflux mechanism among fluoroquinolone-resistant clinical isolates of Streptococcus pneumoniae Antimicrob Agents Chemother 42 1998 2032 2035
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 2032-2035
-
-
Brenwald, N.P.1
Gill, M.J.2
Wise, R.3
-
26
-
-
0034812101
-
Single- and multi-step resistance selection study of gemifloxacin compared with trovafloxacin, ciprofloxacin, gatifloxacin and moxifloxacin in Streptococcus pneumoniae
-
K. Nagai, T.A. Davies, B.E. Dewasse, M.R. Jacobs, and P.C. Appelbaum Single- and multi-step resistance selection study of gemifloxacin compared with trovafloxacin, ciprofloxacin, gatifloxacin and moxifloxacin in Streptococcus pneumoniae J Antimicrob Chemother 48 2001 365 374
-
(2001)
J Antimicrob Chemother
, vol.48
, pp. 365-374
-
-
Nagai, K.1
Davies, T.A.2
Dewasse, B.E.3
Jacobs, M.R.4
Appelbaum, P.C.5
-
27
-
-
10744222278
-
Emergence of a fluoroquinolone-resistant strain of Streptococcus pneumoniae in England
-
A.P. Johnson, C.L. Sheppard, and S.J. Harnett Emergence of a fluoroquinolone-resistant strain of Streptococcus pneumoniae in England J Antimicrob Chemother 52 2003 953 960
-
(2003)
J Antimicrob Chemother
, vol.52
, pp. 953-960
-
-
Johnson, A.P.1
Sheppard, C.L.2
Harnett, S.J.3
-
28
-
-
0036168493
-
Expression of efflux pump gene pmrA in fluoroquinolone-resistant and -susceptible clinical isolates of Streptococcus pneumoniae
-
L.J.V. Piddock, M.M. Johnson, S. Simgee, and L. Pumbwe Expression of efflux pump gene pmrA in fluoroquinolone-resistant and -susceptible clinical isolates of Streptococcus pneumoniae Antimicrob Agents Chemother 46 2002 808 812
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 808-812
-
-
Piddock, L.J.V.1
Johnson, M.M.2
Simgee, S.3
Pumbwe, L.4
-
29
-
-
0035189079
-
Increasing resistance of Streptococcus pneumoniae to fluoroquinolones: Results of a Hong Kong multicentre study in
-
P.L. Ho, R.W. Yung, and D.N. Tsang Increasing resistance of Streptococcus pneumoniae to fluoroquinolones: results of a Hong Kong multicentre study in. J Antimicrob Chemother 48 2001 659 665
-
(2001)
J Antimicrob Chemother
, vol.48
, pp. 659-665
-
-
Ho, P.L.1
Yung, R.W.2
Tsang, D.N.3
-
30
-
-
0031755687
-
Activities of new fluoroquinolones against fluoroquinolone-resistant pathogens of the lower respiratory tract
-
L.J.V. Piddock, M. Johnson, V. Ricci, and S.L. Hill Activities of new fluoroquinolones against fluoroquinolone-resistant pathogens of the lower respiratory tract Antimicrob Agents Chemother 42 1998 2956 2960
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 2956-2960
-
-
Piddock, L.J.V.1
Johnson, M.2
Ricci, V.3
Hill, S.L.4
-
31
-
-
0032978288
-
Pharmacodynamic comparisons of levofloxacin, ciprofloxacin, and ampicillin against Streptococcus pneumoniae in an in vitro model of infection
-
M.K. Lacy, W. Lu, and X. Xu Pharmacodynamic comparisons of levofloxacin, ciprofloxacin, and ampicillin against Streptococcus pneumoniae in an in vitro model of infection Antimicrob Agents Chemother 43 1999 672 677
-
(1999)
Antimicrob Agents Chemother
, vol.43
, pp. 672-677
-
-
Lacy, M.K.1
Lu, W.2
Xu, X.3
-
32
-
-
0035044537
-
In vitro pharmacodynamic modelling simulating free serum concentrations of fluoroquinolones against multidrug-resistant Streptococcus pneumoniae
-
G.G. Zhanel, M. Walters, N. Laing, and D.J. Hoban In vitro pharmacodynamic modelling simulating free serum concentrations of fluoroquinolones against multidrug-resistant Streptococcus pneumoniae J Antimicrob Chemother 47 2001 435 440
-
(2001)
J Antimicrob Chemother
, vol.47
, pp. 435-440
-
-
Zhanel, G.G.1
Walters, M.2
Laing, N.3
Hoban, D.J.4
-
33
-
-
0035019811
-
Activities of newer fluoroquinolones against ciprofloxacin-resistant Streptococcus pneumoniae
-
E.A. Coyle, G.W. Kaatz, and M.J. Rybak Activities of newer fluoroquinolones against ciprofloxacin-resistant Streptococcus pneumoniae Antimicrob Agents Chemother 45 2001 1654 1659
-
(2001)
Antimicrob Agents Chemother
, vol.45
, pp. 1654-1659
-
-
Coyle, E.A.1
Kaatz, G.W.2
Rybak, M.J.3
-
34
-
-
0036001176
-
Pharmacodynamic activity of fluoroquinolones against ciprofloxacin- resistant Streptococcus pneumoniae
-
G.G. Zhanel, D. Roberts, and A. Waltky Pharmacodynamic activity of fluoroquinolones against ciprofloxacin-resistant Streptococcus pneumoniae J Antimicrob Chemother 49 2002 807 812
-
(2002)
J Antimicrob Chemother
, vol.49
, pp. 807-812
-
-
Zhanel, G.G.1
Roberts, D.2
Waltky, A.3
-
35
-
-
0037416982
-
Mechanism of fluoroquinolone resistance is an important factor in determining the antimicrobial effect of gemifloxacin against Streptococcus pneumoniae in an in vitro pharmacokinetic model
-
A.P. MacGowan, and K.E. Bowker Mechanism of fluoroquinolone resistance is an important factor in determining the antimicrobial effect of gemifloxacin against Streptococcus pneumoniae in an in vitro pharmacokinetic model Antimicrob Agents Chemother 47 2003 1096 1100
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 1096-1100
-
-
MacGowan, A.P.1
Bowker, K.E.2
-
36
-
-
0036743908
-
Pharmacodynamics of 750 mg and 500 mg doses of levofloxacin against ciprofloxacin-resistant strains of Streptococcus pneumoniae
-
P.D. Lister Pharmacodynamics of 750 mg and 500 mg doses of levofloxacin against ciprofloxacin-resistant strains of Streptococcus pneumoniae Diagn Microbiol Infect Dis 44 2002 43 49
-
(2002)
Diagn Microbiol Infect Dis
, vol.44
, pp. 43-49
-
-
Lister, P.D.1
-
37
-
-
0031879743
-
Resistance mechanisms in Pseudomonas aeruginosa and other nonfermentative gram-negative bacteria
-
R.E. Hancock Resistance mechanisms in Pseudomonas aeruginosa and other nonfermentative gram-negative bacteria Clin Infect Dis 27 1998 S93 S99
-
(1998)
Clin Infect Dis
, vol.27
-
-
Hancock, R.E.1
-
38
-
-
0034739007
-
Complete genome sequence of Pseudomonas aeruginosa PA01, an opportunistic pathogen
-
C.K. Stover, X.Q. Pham, and A.L. Erwin Complete genome sequence of Pseudomonas aeruginosa PA01, an opportunistic pathogen Nature 406 6799 2000 959 964
-
(2000)
Nature
, vol.406
, Issue.6799
, pp. 959-964
-
-
Stover, C.K.1
Pham, X.Q.2
Erwin, A.L.3
-
39
-
-
0032787411
-
National Nosocomial Infections Surveillance (NNIS) System report, data summary from January 1990 to May 1999. Issued June 1999
-
NNIS System. National Nosocomial Infections Surveillance (NNIS) System report, data summary from January 1990 to May 1999. Issued June 1999. Am J Infect Control 1999;27:520-32.
-
(1999)
Am J Infect Control
, vol.27
, pp. 520-532
-
-
-
40
-
-
0034426126
-
Substrate specificities of MexAB-OprM, MexCD-OprJ, and MexXY-oprM efflux pumps in Pseudomonas aeruginosa
-
N. Masuda, E. Sakagawa, S. Ohya, N. Gotoh, H. Tsujimoto, and T. Nishino Substrate specificities of MexAB-OprM, MexCD-OprJ, and MexXY-oprM efflux pumps in Pseudomonas aeruginosa Antimicrob Agents Chemother 44 2000 3322 3327
-
(2000)
Antimicrob Agents Chemother
, vol.44
, pp. 3322-3327
-
-
Masuda, N.1
Sakagawa, E.2
Ohya, S.3
Gotoh, N.4
Tsujimoto, H.5
Nishino, T.6
-
41
-
-
0033994786
-
Assignment of the substrate-selective subunits of the MexEF-OprN multidrug efflux pump of Pseudomonas aeruginosa
-
H. Maseda, H. Yoneyama, and T. Nakae Assignment of the substrate-selective subunits of the MexEF-OprN multidrug efflux pump of Pseudomonas aeruginosa Antimicrob Agents Chemother 44 2000 658 664
-
(2000)
Antimicrob Agents Chemother
, vol.44
, pp. 658-664
-
-
Maseda, H.1
Yoneyama, H.2
Nakae, T.3
-
42
-
-
0141963102
-
A new member of the tripartitie multidrug efflux pumps, Mex-VW-OprM, in Pseudomonas aeruginosa
-
Y. Li, T. Mima, and Y. Komori A new member of the tripartitie multidrug efflux pumps, Mex-VW-OprM, in Pseudomonas aeruginosa J Antimicrob Chemother 52 2003 572 575
-
(2003)
J Antimicrob Chemother
, vol.52
, pp. 572-575
-
-
Li, Y.1
Mima, T.2
Komori, Y.3
-
43
-
-
0033031244
-
Use of a genetic approach to evaluate the consequences of inhibition of efflux pumps in Pseudomonas aeruginosa
-
O. Lomovskaya, A. Lee, and HoshinoF K. Use of a genetic approach to evaluate the consequences of inhibition of efflux pumps in Pseudomonas aeruginosa Antimicrob Agents Chemother 43 1999 1340 1346
-
(1999)
Antimicrob Agents Chemother
, vol.43
, pp. 1340-1346
-
-
Lomovskaya, O.1
Lee, A.2
Hoshino, F.K.3
-
44
-
-
0034757528
-
Fluoroquinolone susceptibilities of efflux-mediated multidrug-resistant Pseudomonas aeruginosa, Stenotrophomonas maltophilia and Burkholderia cepacia
-
L. Zhang, X.Z. Li, and K. Poole Fluoroquinolone susceptibilities of efflux-mediated multidrug-resistant Pseudomonas aeruginosa, Stenotrophomonas maltophilia and Burkholderia cepacia J Antimicrob Chemother 48 2001 549 552
-
(2001)
J Antimicrob Chemother
, vol.48
, pp. 549-552
-
-
Zhang, L.1
Li, X.Z.2
Poole, K.3
-
45
-
-
0842307683
-
Role of efflux pumps and mutations in genes for topoisomerase II and IV in fluoroquinolone-resistant Pseudomonas aeruginosa strains
-
H. Oh, J. Stenhoff, S. Jalal, and B. Wretlind Role of efflux pumps and mutations in genes for topoisomerase II and IV in fluoroquinolone-resistant Pseudomonas aeruginosa strains Microb Drug Resist 9 2003 323 328
-
(2003)
Microb Drug Resist
, vol.9
, pp. 323-328
-
-
Oh, H.1
Stenhoff, J.2
Jalal, S.3
Wretlind, B.4
-
46
-
-
0035992752
-
High-level fluoroquinolone resistance in Pseudomonas aeruginosa due to interplay of the MexAB-OprM efflux pump and the DNA gyrase mutation
-
A. Nakajima, Y. Sugimoto, H. Yoneyama, and T. Nakae High-level fluoroquinolone resistance in Pseudomonas aeruginosa due to interplay of the MexAB-OprM efflux pump and the DNA gyrase mutation Microbiol Immunol 46 2002 391 395
-
(2002)
Microbiol Immunol
, vol.46
, pp. 391-395
-
-
Nakajima, A.1
Sugimoto, Y.2
Yoneyama, H.3
Nakae, T.4
-
47
-
-
0037405379
-
Mutations in GyrA, ParC, MexR and NfxB in clinical isolates of Pseudomonas aeruginosa
-
P.G. Higgins, A.C. Fluit, D. Milatovic, J. Verhoef, and F.J. Schmitz Mutations in GyrA, ParC, MexR and NfxB in clinical isolates of Pseudomonas aeruginosa Int J Antimicrob Agents 21 2003 409 413
-
(2003)
Int J Antimicrob Agents
, vol.21
, pp. 409-413
-
-
Higgins, P.G.1
Fluit, A.C.2
Milatovic, D.3
Verhoef, J.4
Schmitz, F.J.5
-
48
-
-
0034757469
-
In vivo selection of a target/efflux double mutant of Pseudomonas aeruginosa by ciprofloxacin therapy
-
I. Le Thomas, G. Couetdic, O. Clermont, N. Brahimi, P. Plesiat, and E. Bingen In vivo selection of a target/efflux double mutant of Pseudomonas aeruginosa by ciprofloxacin therapy J Antimicrob Chemother 48 2001 553 555
-
(2001)
J Antimicrob Chemother
, vol.48
, pp. 553-555
-
-
Le Thomas, I.1
Couetdic, G.2
Clermont, O.3
Brahimi, N.4
Plesiat, P.5
Bingen, E.6
-
49
-
-
0033999155
-
Molecular mechanisms of fluoroquinolone resistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients
-
S. Jalal, O. Ciofu, N. Hoiby, N. Gotoh, and B. Wretlind Molecular mechanisms of fluoroquinolone resistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients Antimicrob Agents Chemother 44 2000 710 712
-
(2000)
Antimicrob Agents Chemother
, vol.44
, pp. 710-712
-
-
Jalal, S.1
Ciofu, O.2
Hoiby, N.3
Gotoh, N.4
Wretlind, B.5
-
50
-
-
2142824217
-
Clinical strains of Pseudomonas areuginosa overproducing Mex-AB-OprM and MexXY efflux pumps simultaneously
-
C. Llanes, D. Hocquet, C. Vogne, D. Benali-Baitich, C. Neuwirth, and P. Plesiat Clinical strains of Pseudomonas areuginosa overproducing Mex-AB-OprM and MexXY efflux pumps simultaneously Antimicrob Agents Chemother 48 2004 1797 1802
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 1797-1802
-
-
Llanes, C.1
Hocquet, D.2
Vogne, C.3
Benali-Baitich, D.4
Neuwirth, C.5
Plesiat, P.6
-
51
-
-
0034115142
-
Interplay between efflux pumps may provide either additive or multiplicative effects on drug resistance
-
A. Lee, W. Mao, and M.S. Warren Interplay between efflux pumps may provide either additive or multiplicative effects on drug resistance J Bacteriol 182 2000 3142 3150
-
(2000)
J Bacteriol
, vol.182
, pp. 3142-3150
-
-
Lee, A.1
Mao, W.2
Warren, M.S.3
-
52
-
-
0030671389
-
Differential selection of multidrug efflux systems by quinolones in Pseudomonas aeruginosa
-
T. Kohler, M. Michea-Hamzehpour, P. Plesiat, A.-L. Kahr, and J.-C. Pechere Differential selection of multidrug efflux systems by quinolones in Pseudomonas aeruginosa Antimicrob Agents Chemother 41 1997 2540 2543
-
(1997)
Antimicrob Agents Chemother
, vol.41
, pp. 2540-2543
-
-
Kohler, T.1
Michea-Hamzehpour, M.2
Plesiat, P.3
Kahr, A.-L.4
Pechere, J.-C.5
-
53
-
-
0035143255
-
Differential selection of multidrug efflux mutants by trovafloxacin and ciprofloxacin in an experimental model of Pseudomonas aeruginosa acute pneumonia in rats
-
O.F. Join-Lambert, M. Michea-Hamzehpour, and T. Kohler Differential selection of multidrug efflux mutants by trovafloxacin and ciprofloxacin in an experimental model of Pseudomonas aeruginosa acute pneumonia in rats Antimicrob Agents Chemother 45 2001 571 576
-
(2001)
Antimicrob Agents Chemother
, vol.45
, pp. 571-576
-
-
Join-Lambert, O.F.1
Michea-Hamzehpour, M.2
Kohler, T.3
-
54
-
-
0033024785
-
The antibacterial efficacy of levofloxacin and ciprofloxacin against Pseudomonas aeruginosa assessed by combining antibiotic exposure and bacterial susceptibility
-
A.P. MacGowan, M. Wootton, and H.A. Holt The antibacterial efficacy of levofloxacin and ciprofloxacin against Pseudomonas aeruginosa assessed by combining antibiotic exposure and bacterial susceptibility J Antimicrob Chemother 43 1999 345 349
-
(1999)
J Antimicrob Chemother
, vol.43
, pp. 345-349
-
-
MacGowan, A.P.1
Wootton, M.2
Holt, H.A.3
-
55
-
-
0029958830
-
A pharmacodynamic evaluation of ciprofloxacin and ofloxacin against two strains of Pseudomonas aeruginosa
-
K.J. Madaras-Kelly, A.J. Larsson, and J.C. Rotschafer A pharmacodynamic evaluation of ciprofloxacin and ofloxacin against two strains of Pseudomonas aeruginosa J Antimicrob Chemother 37 1996 703 710
-
(1996)
J Antimicrob Chemother
, vol.37
, pp. 703-710
-
-
Madaras-Kelly, K.J.1
Larsson, A.J.2
Rotschafer, J.C.3
-
56
-
-
0042743965
-
Application of a mathematical model to prevent in vivo amplification of antibiotic-resistant bacterial populations during therapy
-
N. Jumbe, A. Louie, and R. Leary Application of a mathematical model to prevent in vivo amplification of antibiotic-resistant bacterial populations during therapy J Clin Invest 112 2003 275 285
-
(2003)
J Clin Invest
, vol.112
, pp. 275-285
-
-
Jumbe, N.1
Louie, A.2
Leary, R.3
-
57
-
-
2442549489
-
Relationship between fluoroquinolone area under the curve:minimum inhibitory concentration ratio and the probability of eradication of the infecting pathogen, in patients with nosocomial pneumonia
-
G.L. Drusano, S.L. Preston, C. Fowler, M. Corrado, B. Wiesinger, and J. Kahn Relationship between fluoroquinolone area under the curve:minimum inhibitory concentration ratio and the probability of eradication of the infecting pathogen, in patients with nosocomial pneumonia J Infect Dis 189 2004 1590 1597
-
(2004)
J Infect Dis
, vol.189
, pp. 1590-1597
-
-
Drusano, G.L.1
Preston, S.L.2
Fowler, C.3
Corrado, M.4
Wiesinger, B.5
Kahn, J.6
-
58
-
-
0032942964
-
Inhibition of the emergence of ciprofloxacin resistance in Streptococcus pneumoniae by the multidrug efflux inhibitor reserpine
-
P.N. Markham Inhibition of the emergence of ciprofloxacin resistance in Streptococcus pneumoniae by the multidrug efflux inhibitor reserpine Antimicrob Agents Chemother 43 1999 988 989
-
(1999)
Antimicrob Agents Chemother
, vol.43
, pp. 988-989
-
-
Markham, P.N.1
-
59
-
-
0030805166
-
Active efflux as a mechanism of resistance to ciprofloxacin in Streptococcus pneumoniae
-
V. Zeller, C. Janoir, M.-D. Kitzis, L. Gutmann, and N.J. Moreau Active efflux as a mechanism of resistance to ciprofloxacin in Streptococcus pneumoniae Antimicrob Agents Chemother 41 1997 1973 1978
-
(1997)
Antimicrob Agents Chemother
, vol.41
, pp. 1973-1978
-
-
Zeller, V.1
Janoir, C.2
Kitzis, M.-D.3
Gutmann, L.4
Moreau, N.J.5
-
60
-
-
0344717988
-
Inhibitors of efflux pumps in Pseudomonas aeruginosa potentiate the activity of the fluoroquinolone antibacterial levofloxacin
-
T.E. Renau, R. Leger, and E.M. Flamme Inhibitors of efflux pumps in Pseudomonas aeruginosa potentiate the activity of the fluoroquinolone antibacterial levofloxacin J Med Chem 42 1999 4928 4931
-
(1999)
J Med Chem
, vol.42
, pp. 4928-4931
-
-
Renau, T.E.1
Leger, R.2
Flamme, E.M.3
-
61
-
-
1842830032
-
A multidrug efflux inhibitor reduces fluoroquinolone resistance in Pseudomonas aeruginosa isolates
-
A.Y. Coban, B. Ekinci, and B. Durupinar A multidrug efflux inhibitor reduces fluoroquinolone resistance in Pseudomonas aeruginosa isolates Chemotherapy 50 2004 22 26
-
(2004)
Chemotherapy
, vol.50
, pp. 22-26
-
-
Coban, A.Y.1
Ekinci, B.2
Durupinar, B.3
-
62
-
-
0242569169
-
MexAB-OprM-specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 1: Discovery and early strategies for lead optimization
-
K. Nakayama, Y. Ishida, and M. Ohtsuka MexAB-OprM-specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 1: discovery and early strategies for lead optimization Bioorg Med Chem Lett 13 2003 4201 4204
-
(2003)
Bioorg Med Chem Lett
, vol.13
, pp. 4201-4204
-
-
Nakayama, K.1
Ishida, Y.2
Ohtsuka, M.3
-
63
-
-
10744222660
-
MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 2: Achieving activity in vivo through the use of alternative scaffolds
-
K. Nakayama, Y. Ishida, and M. Ohtsuka MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 2: achieving activity in vivo through the use of alternative scaffolds Bioorg Med Chem Lett 13 2003 4205 4208
-
(2003)
Bioorg Med Chem Lett
, vol.13
, pp. 4205-4208
-
-
Nakayama, K.1
Ishida, Y.2
Ohtsuka, M.3
-
64
-
-
12444345510
-
Conformationally-restricted analogues of efflux pump inhibitors that potentiate the activity of levofloxacin in Pseudomonas aeruginosa
-
T.E. Renau, R. Leger, and L. Filonova Conformationally-restricted analogues of efflux pump inhibitors that potentiate the activity of levofloxacin in Pseudomonas aeruginosa Bioorg Med Chem Lett 13 2003 2755 2758
-
(2003)
Bioorg Med Chem Lett
, vol.13
, pp. 2755-2758
-
-
Renau, T.E.1
Leger, R.2
Filonova, L.3
-
65
-
-
0037060903
-
Peptidomimetics of efflux pump inhibitors potentiate the activity of levofloxacin in Pseudomonas aeruginosa
-
T.E. Renau, R. Leger, and R. Yen Peptidomimetics of efflux pump inhibitors potentiate the activity of levofloxacin in Pseudomonas aeruginosa Bioorg Med Chem Lett 12 2002 763 766
-
(2002)
Bioorg Med Chem Lett
, vol.12
, pp. 763-766
-
-
Renau, T.E.1
Leger, R.2
Yen, R.3
-
66
-
-
10744228144
-
The relationship between physicochemical properties, in vitro activity and pharmacokinetic profiles of analogues of diamine-containing efflux pump inhibitors
-
W.J. Watkins, Y. Landaverry, and R. Leger The relationship between physicochemical properties, in vitro activity and pharmacokinetic profiles of analogues of diamine-containing efflux pump inhibitors Bioorg Med Chem Lett 13 2003 4241 4244
-
(2003)
Bioorg Med Chem Lett
, vol.13
, pp. 4241-4244
-
-
Watkins, W.J.1
Landaverry, Y.2
Leger, R.3
-
67
-
-
0032173598
-
Multiple antibiotic resistance and efflux
-
H. Nikaido Multiple antibiotic resistance and efflux Curr Opin Microbiol 1 1998 516 523
-
(1998)
Curr Opin Microbiol
, vol.1
, pp. 516-523
-
-
Nikaido, H.1
-
68
-
-
0034917313
-
Steady-state plasma and intrapulmonary concentrations of levofloxacin and ciprofloxacin in healthy adult subjects
-
M.H. Gotfried, L.H. Danziger, and K.A. Rodvold Steady-state plasma and intrapulmonary concentrations of levofloxacin and ciprofloxacin in healthy adult subjects Chest 119 2001 1114 1122
-
(2001)
Chest
, vol.119
, pp. 1114-1122
-
-
Gotfried, M.H.1
Danziger, L.H.2
Rodvold, K.A.3
|