Substrate specificities of MexAB-OprM, MexCD-OprJ, and MexXY-OprM efflux pumps in Pseudomonas aeruginosa

Antimicrobial Agents and Chemotherapy

Volumn 44, Issue 12, 2000, Pages 3322-3327

  Masuda, N ^a   Sakagawa, E ^a   Ohya, S ^a   Gotoh, N ^a   Tsujimoto, H ^a   Nishino, T ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZTREONAM; BACTERIAL PROTEIN; CARBENICILLIN; CEFSULODIN; CEFTAZIDIME; CEPHEM DERIVATIVE; CHLORAMPHENICOL DERIVATIVE; CINOXACIN; DORIPENEM; ENOXACIN; ERYTHROMYCIN; FLOMOXEF; IMIPENEM; LATAMOXEF; LINCOMYCIN; MACROLIDE; MEROPENEM; MEXAB PROTEIN; MEXCD PROTEIN; MEXXY PROTEIN; NALIDIXIC ACID; NORFLOXACIN; NOVOBIOCIN; OFLOXACIN; OPRJ PROTEIN; OPRM PROTEIN; PENICILLIN DERIVATIVE; PIPEMIDIC ACID; PIROMIDIC ACID; POLYMYXIN B; QUINOLONE DERIVATIVE; SULBENICILLIN; TETRACYCLINE DERIVATIVE; TOSUFLOXACIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; CHROMOSOME; EFFUSION; ENZYME SPECIFICITY; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA;

BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL PROTEINS; BIOLOGICAL TRANSPORT, ACTIVE; CARRIER PROTEINS; LACTAMS; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MUTATION; PSEUDOMONAS AERUGINOSA; SUBSTRATE SPECIFICITY;

EID: 0034426126     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.44.12.3322-3327.2000     Document Type: Article

References (27)

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4. Functional replacement of OprJ by OprM in the MexCDOprJ multidrug efflux system of Pseudomonas aeruginosa
5. A novel 1 beta-methylcarbapenem antibiotic, S-4661. Synthesis and structure-activity relationships of 2-(5-substituted pyrrolidin-3-ylthio)-1- beta-methylcarbapenems
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