α-1-C-Alkyl-1-deoxynojirimycin derivatives as potent and selective inhibitors of intestinal isomaltase: Remarkable effect of the alkyl chain length on glycosidase inhibitory profile

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 24, 2004, Pages 5991-5995

  Godin, Guillaume ^a   Compain, Philippe ^a   Martin, Olivier R ^a   Ikeda, Kyoko ^b   Yu, Liang ^b   Asano, Naoki ^b  

^a UNIVERSITÉ D'ORLÉANS   (France)

^b HOKURIKU UNIVERSITY   (Japan)

Author keywords

Glycosidase inhibitors; Iminosugars; Isomaltase

Indexed keywords

1 DEOXYNOJIRIMYCIN DERIVATIVE; ALPHA C HEXYL 1 DEOXYNOJIRIMYCIN; ALPHA1 C NONYL DEOXYNOJIRIMYCIN; GLYCOSIDASE INHIBITOR; INTESTINE ENZYME; OLIGO 1,6 GLUCOSIDASE; UNCLASSIFIED DRUG;

ARTICLE; BIOASSAY; DRUG EFFICACY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME SPECIFICITY; IC 50;

1-DEOXYNOJIRIMYCIN; ANIMALS; EVALUATION STUDIES; GLYCOSIDE HYDROLASES; INTESTINE, SMALL; MOLECULAR STRUCTURE; OLIGO-1,6-GLUCOSIDASE; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 8844262688     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.09.086     Document Type: Article

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