Inhibition of lymphocyte activation and function by the prenylation inhibitor L-778,123

Investigational New Drugs

Volumn 23, Issue 1, 2005, Pages 21-29

  Si, Ming Sing ^a   Reitz, Bruce A ^a   Borie, Dominic C ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

immunosuppression; interleukin 2; lymphocyte activation; prenylation inhibitor

Indexed keywords

CD71 ANTIGEN; CYCLOSPORIN; INTERLEUKIN 2 RECEPTOR; L 778123; LECTIN; PHYTOHEMAGGLUTININ; THYMIDINE;

APOPTOSIS; ARTICLE; AUTOIMMUNE DISEASE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC 50; LYMPHOCYTE FUNCTION; MEASUREMENT; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRENYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

ANTIGENS, CD28; ANTIGENS, CD80; APOPTOSIS; CELL PROLIFERATION; CYCLOSPORINE; DIMETHYLALLYLTRANSTRANSFERASE; ENZYME INHIBITORS; FLOW CYTOMETRY; HUMANS; IMIDAZOLES; INTERFERON TYPE II; INTERLEUKIN-2; LIGANDS; LYMPHOCYTE ACTIVATION; PROTEIN ISOPRENYLATION; RECEPTORS, INTERLEUKIN-2; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 8644285459     PISSN: 01676997     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:DRUG.0000047102.26698.08     Document Type: Article

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