Genistein stimulates electrogenic Cl- secretion in mouse jejunum

American Journal of Physiology - Cell Physiology

Volumn 287, Issue 6 56-6, 2004, Pages

  Baker, Michael J ^a   Hamilton, Kirk L ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

1 ethyl 2 benzimidazolone; Cantharidic acid; Phosphatase; Tyrphostin A23; Vanadate

Indexed keywords

1 ETHYL 2 BENZIMIDAZOLONE; ACID; BENZIMIDAZOLE DERIVATIVE; BUMETANIDE; CANTHARIDIC ACID; CHLORIDE ION; CLOTRIMAZOLE; CYCLIC AMP; DIMETHYL SULFOXIDE; FORSKOLIN; GENISTEIN; GLIBENCLAMIDE; TYRPHOSTIN; TYRPHOSTIN A23; UNCLASSIFIED DRUG; VANADIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; JEJUNUM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SHORT CIRCUIT CURRENT;

ANIMALS; ANTICARCINOGENIC AGENTS; BENZIMIDAZOLES; CALCIUM CHANNEL AGONISTS; CHLORIDES; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; GENISTEIN; JEJUNUM; MALE; MICE; PHOSPHORYLATION; SECRETORY VESICLES; VANADATES;

ANIMALIA;

EID: 8644279691     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00236.2003     Document Type: Article

References (60)

1. Akiyama T, Ishida J, Nakagawa S, Ogawara H, Watanabe SI, Itoh N, Shibuya M, and Fukami Y. Genistein, a specific inhibitor of tyrosine-specific protein kinases. J Biol Chem 262: 5592-5595, 1987.
2. Akiyama T and Ogawara H. Use and specificity of genistein as inhibitor of protein-tyrosine kinases. Methods Enzymol 221: 362-370, 1991.
3. Al-Nakkash L, Hu S, Li M, and Hwang TC. A common mechanism for cystic fibrosis transmembrane conductance regulator protein activation by genistein and benzimidazolone analogs. J Pharmacol Exp Ther 296: 464-472, 2001.
4. Ameen N, Alexis J, and Salas P. Cellular localization of the cystic fibrosis transmembrane conductance regulator in mouse intestinal tract. Histochem Cell Biol 114: 69-75, 2000.
5. Becq F, Jensen TJ, Chang XB, Savoia A, Rommens JM, Tsui LC, Buchwald M, Riordan JR, and Hanrahan JW. Phosphatase inhibitors activate normal and defective CFTR chloride channels. Proc Natl Acad Sci USA 91: 9160-9164, 1994.
6. - channel by specific protein kinases and protein phosphatases. J Biol Chem 268: 2037-2047, 1993.
7. Bhathena SJ and Velasquez MT. Beneficial role of phytoestrogens in obesity and diabetes. Am J Clin Nutr 76: 1191-1201, 2002.
8. Butt AG, Bowler JM, and McLaughlin C. Villus and crypt cell composition in the secreting mouse jejunum measured with x-ray microanalysis. J Membr Biol 162: 17-29, 1998.
9. Butt AG and Hamilton KL. Ion channels in isolated mouse jejunal crypts. Pflügers Arch 435: 528-538, 1998.
10. Chang EB and Rao MC. Intestinal water and electrolyte transport-mechanisms of physiological and adaptive responses. In: Physiology of the Gastrointestinal Tract (3rd ed.), edited by Johnson LR. New York: Raven, 1994, vol. 1 and 2, p. 2027-2081.
11. Chang PC, Chen TH, Chang CJ, Huo CC, Chan P, and Lee HM. Advanced glycosylation end products induce inducible nitric oxide synthase (iNOS) expression via a p38 MAPK-dependent pathway. Kidney Int 65: 1664-1675, 2004.
12. + channels in murine colonie epithelia by 1-ethyl-2-benzimidazolone. Am J Physiol Cell Physiol 277: C111-C120, 1999.
13. Devor DC, Bridges RJ, and Pilewski JM. Pharmacological modulation of ion transport across wild-type and ΔF508 CFTR-expressing human bronchial epithelia. Am J Physiol Cell Physiol 279: C461-C479, 2000.
14. K. Am J Physiol Lung Cell Mol Physiol 271: L785-L795, 1996.
15. + channel. Am J Physiol Lung Cell Mol Physiol 271: L775-L784, 1996.
16. + channels. Am J Physiol Cell Physiol 273: C531-C540, 1997.
17. - secretion in rat distal colon by genistein, a protein tyrosine kinase inhibitor. Eur J Pharmacol 299: 161-170, 1996.
18. Dixon RA and Ferreira D. Genistein. Phytochemistry 60: 205-211, 2002.
19. Field M. Ion transport in rabbit ileal mucosa. II. Effects of cyclic 3′,5′-AMP. Am J Physiol 221: 992-997, 1971.
20. Flatman PW. Regulation of Na-K-2Cl cotransport by phosphorylation and protein-protein interactions. Biochim Biophys Acta 1566: 140-151, 2002.
21. - channels via a tyrosine kinase-and protein phosphatase-independent mechanism. Am J Physiol Cell Physiol 273: C747-C753, 1997.
22. Gadsby DC and Nairn AC. Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis. Physiol Rev 79: S77-S107, 1999.
23. Gazit A, Yaish P, Gilon C, and Levitzki A. Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors. J Med Chem 32: 2344-2352, 1989.
24. - secretion in the murine trachea and colon. Am J Physiol Cell Physiol 279: C383-C392, 2000.
25. Gordon JA. Use of vanadate as protein-phosphotyrosine phosphatase inhibitor. Methods Enzymol 201: 477-482, 1991.
26. Grubb BR. Ion transport across the jejunum in normal and cystic fibrosis mice. Am J Physiol Gastrointest Liver Physiol 268: G505-G513, 1995.
27. - secretion in the mouse jejunum. Exp Physiol 87: 437-445, 2002.
28. + channel in the mouse jejunum. Pflügers Arch 439: 158-166, 1999.
29. Honkanen RE. Cantharidin, another natural toxin that inhibits the activity of serine/threonine protein phosphatases types 1 and 2A. FEBS Lett 330: 283-286, 1993.
30. Huang J, Nasr M, Kim Y, and Matthews HR. Genistein inhibits protein histidine kinase. J Biol Chem 267: 15511-15515, 1992.
31. Hubel KA. The effects of electrical field stimulation and tetrodotoxin on ion transport by the isolated rabbit ileum. J Clin Invest 62: 1039-1047, 1978.
32. Hwang TC, Wang F, Yang ICH, and Reenstra WW. Genistein potentiates wild-type and ΔF508-CFTR channel activity. Am J Physiol Cell Physiol 273: C988-C998, 1997.
33. Illek B and Fischer H. Flavonoids stimulate Cl conductance of human airway epithelium in vitro and in vivo. Am J Physiol Lung Cell Mol Physiol 275: L902-L910, 1998.
34. Illek B, Fischer H, and Machen TE. Alternate stimulation of apical CFTR by genistein in epithelia. Am J Physiol Cell Physiol 270: C265-C275, 1996.
35. Illek B, Fischer H, Santos GF, Widdicombe JH, Machen TE, and Reenstra WW. cAMP-independent activation of CFTR Cl channels by the tyrosine kinase inhibitor genistein. Am J Physiol Cell Physiol 268: C886-C893, 1995.
36. Kuiper GGJM, Lemmen JG, Carlsson B, Corton JC, Safe SH, van der Saag PT, van der Burg B, and Gustafsson JA. Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor β. Endocrinology 139: 4252-4263, 1998.
37. Kunzelmann K and Mall M. Pharmacotherapy of the ion transport defect in cystic fibrosis. Clin Exp Pharmacol Physiol 28: 857-867, 2001.
38. Lamartiniere CA, Cotroneo MS, Fritz WA, Wang J, Mentor-Marcel R, and Elgavish A. Genistein chemoprevention: timing and mechanisms of action in mammary and prostate. J Nutr 132: 552S-558S, 2002.
39. Lehrich RW and Forrest JN Jr. Tyrosine phosphorylation is a novel pathway for regulation of chloride secretion in shark rectal gland. Am J Physiol Renal Fluid Electrolyte Physiol 269: F594-F600, 1995.
40. Luo J, Pato MD, Riordan JR, and Hanrahan JW. Differential regulation of single CFTR channels by PP2C, PP2A and other phosphatases. Am J Physiol Cell Physiol 274: C1397-C1410, 1998.
41. Mall M, Wissner A, Seydewitz HH, Hubner M, Kuehr J, Brandis M, Greger M, and Kunzelmann K. Effect of genistein on native epithelial tissue from normal individuals and CF patients and on ion channels expressed in Xenopus oocytes. Br J Pharmacol 130: 1884-1892, 2000.
42. Markovits J, Linassier C, Fosse P, Couprie J, Pierre J, Jacquemin-Sablon A, Saucier JM, Le Pecq JB, and Larsen AK. Inhibitory effects of the tyrosine kinase inhibitor genistein on mammalian DNA topisomerase II. Cancer Res 49: 5111-5117, 1989.
43. - cotransporter in renal epithelial A6 cells by flavonoids: genistein, daidzein, and apigenin. Biochem Biophys Res Commun 254: 368-371, 1999.
44. - cotransporter via a PTK-dependent pathway in renal epithelium. Biochem Biophys Res Commun 285: 880-884, 2001.
45. Randak C, Auerswald EA, Assfalg-Machleidt I, Reenstra WW, and Machleidt W. Inhibition of ATPase, GTPase and adenylate kinase activities of the second nucleotide-binding fold of the cystic fibrosis transmembrane conductance regulator by genistein. Biochem J 340: 227-235, 1999.
46. Reenstra WW, Yurko-mauro K, Dam A, Raman S, and Shorten S. CFTR chloride channel activation by genistein: The role of serine/threonine protein phosphatases. Am J Physiol Cell Physiol 271: C650-C657, 1996.
47. Reuss L. Epithelial transport. In: Handbook of Physiology. Cell Physiology. Bethesda. MD: Am Physiol Soc 1997, sect. 14, chapt. 8, p. 309-388, 1997.
48. Roomans GM. Pharmacological treatment of the ion transport defect in cystic fibrosis. Expert Opin Investig Drugs 10: 1-19, 2001.
49. Saad AH, Kuo SS, Koong AC, Hahn GM, and Giaccia AJ. Modulation of potassium channels by protein tyrosine kinase inhibitors. J Cell Physiol 161: 142-148, 1994.
50. Schultz BD, Singh AK, Bevor DC, and Bridges RJ. Pharmacology of CFTR chloride channel activity. Physiol Rev 79: S109-S144, 1999.
51. Scuro L, Simioni PU, Gabriel D, Saviani E, Modolo L, Tamashiro W, and Salgado I. Suppression of nitric oxide production in mouse macrophages by soybean flavonoids accumulated in response to nitroprusside and fungal elicitation. BMC Biochem 5: 5, 2004 (www.biomedcentral. com/1471-2091/5/5).
52. - secretion in T84 cell monolayers. Am J Physiol Gastrointest Liver Physiol 269: G874-G882, 1995.
53. Sheppard DN and Welsh MJ. Structure and function of the CFTR chloride channel. Physiol Rev 79: S23-S45, 1999.
54. Travis SM, Berger HA, and Welsh MJ. Protein phosphatase 2C dephosphorylates and inactivates cystic fibrosis transmembrane conductance regulator. Proc Natl Acad Sci USA 94: 11055-11060, 1997.
55. Wang F, Zeltwanger S, Yang ICH, Nairn AC, and Hwang TC. Actions of genistein on cystic fibrosis transmembrane conductance regulator channel gating. Evidence for two binding sites with opposite effects. J Gen Physiol 111: 477-490, 1998.
56. Wang W, Lerea KM, Chan M, and Giebisch G. Protein tyrosine kinase regulates the number of renal secretory K channels. Am J Physiol Renal Physiol 278: F165-F171, 2000.
57. Weinreich F, Wood PG, Riordan JR, and Nagel G. Direct action of genistein on CFTR. Pflugers Arch 434: 484-491, 1997.
58. Welsh MJ, Smith PL, Fromm M, and Frizzell RA. Crypts are the site of intestinal fluid and electrolyte secretion. Science 218: 1219-1221, 1982.
59. c-src kinase activity. Br J Pharmacol 129: 1347-1354, 2000.
60. Yang ICH, Cheng TH, Wang F, Price EM, and Hwang TC. Modulation of CFTR chloride channels by calyculin A and genistein. Am J Physiol Cell Physiol 272: C142-C155, 1997.