Actions of genistein on cystic fibrosis transmembrane conductance regulator channel gating: Evidence for two binding sites with opposite effects

Journal of General Physiology

Volumn 111, Issue 3, 1998, Pages 477-490

  Wang, Fei ^a   Zeltwanger, Shawn ^a   Yang, Iris C H ^a   Nairn, Angus C ^b   Hwang, Tzyh Chang ^a,c  

^a University of Missouri   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c UNIVERSITY OF MISSOURI   (United States)

Author keywords

ATP hydrolysis; Cystic fibrosis; Dephosphorylation; Phosphorylation

Indexed keywords

GENISTEIN; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ARTICLE; BINDING SITE; CHANNEL GATING; CONCENTRATION RESPONSE; CYSTIC FIBROSIS; DEPHOSPHORYLATION; DOSE RESPONSE; DRUG MECHANISM; ENZYME INHIBITION; HYDROLYSIS; NONHUMAN; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; BINDING SITES; CELLS, CULTURED; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ENZYME INHIBITORS; GENISTEIN; INSECTS; ION CHANNEL GATING; ION CHANNELS; KINETICS; MEMBRANE POTENTIALS; PHOSPHORYLATION;

EID: 0031881489     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.111.3.477     Document Type: Article

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