-
1
-
-
84884365015
-
The causes and consequences of genetic heterogeneity in cancer evolution
-
Burrell RA, McGranahan N, Bartek J, Swanton C. The causes and consequences of genetic heterogeneity in cancer evolution. Nature. 2013; 501(7467):338-345.
-
(2013)
Nature
, vol.501
, Issue.7467
, pp. 338-345
-
-
Burrell, RA1
McGranahan, N2
Bartek, J3
Swanton, C.4
-
2
-
-
84863393080
-
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
-
Gerlinger M, et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med. 2012; 366(10):883-892.
-
(2012)
N Engl J Med
, vol.366
, Issue.10
, pp. 883-892
-
-
Gerlinger, M1
-
3
-
-
84895876130
-
Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing
-
Gerlinger M, et al. Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing. Nat Genet. 2014; 46(3):225-233.
-
(2014)
Nat Genet
, vol.46
, Issue.3
, pp. 225-233
-
-
Gerlinger, M1
-
4
-
-
84907808265
-
Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing
-
Zhang J, et al. Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing. Science. 2014; 346(6206):256-259.
-
(2014)
Science
, vol.346
, Issue.6206
, pp. 256-259
-
-
Zhang, J1
-
5
-
-
84936890500
-
Subclonal diversification of primary breast cancer revealed by multiregion sequencing
-
Yates LR, et al. Subclonal diversification of primary breast cancer revealed by multiregion sequencing. Nat Med. 2015; 21(7):751-759.
-
(2015)
Nat Med
, vol.21
, Issue.7
, pp. 751-759
-
-
Yates, LR1
-
6
-
-
84933277410
-
Spatial genomic heterogeneity within localized, multifocal prostate cancer
-
Boutros PC, et al. Spatial genomic heterogeneity within localized, multifocal prostate cancer. Nat Genet. 2015; 47(7):736-745.
-
(2015)
Nat Genet
, vol.47
, Issue.7
, pp. 736-745
-
-
Boutros, PC1
-
7
-
-
84942036061
-
Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA
-
Izumchenko E, et al. Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA. Nat Commun. 2015; 6:8258.
-
(2015)
Nat Commun
, vol.6
, pp. 8258
-
-
Izumchenko, E1
-
8
-
-
84938770152
-
Tracking the genomic evolution of esophageal adenocarcinoma through neoadjuvant chemotherapy
-
Murugaesu N, et al. Tracking the genomic evolution of esophageal adenocarcinoma through neoadjuvant chemotherapy. Cancer Discov. 2015; 5(8):821-831.
-
(2015)
Cancer Discov
, vol.5
, Issue.8
, pp. 821-831
-
-
Murugaesu, N1
-
9
-
-
84938799837
-
Toward understanding and exploiting tumor heterogeneity
-
Alizadeh AA, et al. Toward understanding and exploiting tumor heterogeneity. Nat Med. 2015; 21(8):846-853.
-
(2015)
Nat Med
, vol.21
, Issue.8
, pp. 846-853
-
-
Alizadeh, AA1
-
10
-
-
84937970942
-
Tumorigenesis: it takes a village
-
Tabassum DP, Polyak K. Tumorigenesis: it takes a village. Nat Rev Cancer. 2015; 15(8):473-483.
-
(2015)
Nat Rev Cancer
, vol.15
, Issue.8
, pp. 473-483
-
-
Tabassum, DP1
Polyak, K.2
-
11
-
-
84898402897
-
Multiplexed ion beam imaging of human breast tumors
-
Angelo M, et al. Multiplexed ion beam imaging of human breast tumors. Nat Med. 2014; 20(4):436-442.
-
(2014)
Nat Med
, vol.20
, Issue.4
, pp. 436-442
-
-
Angelo, M1
-
12
-
-
84897954497
-
Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry
-
Giesen C, et al. Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry. Nat Methods. 2014; 11(4):417-422.
-
(2014)
Nat Methods
, vol.11
, Issue.4
, pp. 417-422
-
-
Giesen, C1
-
13
-
-
84887776507
-
Fast chemical imaging at high spatial resolution by laser ablation inductively coupled plasma mass spectrometry
-
Wang HA, et al. Fast chemical imaging at high spatial resolution by laser ablation inductively coupled plasma mass spectrometry. Anal Chem. 2013; 85(21):10107-10116.
-
(2013)
Anal Chem
, vol.85
, Issue.21
, pp. 10107-10116
-
-
Wang, HA1
-
14
-
-
84897402237
-
Next-gen immunohistochemistry
-
Rimm DL. Next-gen immunohistochemistry. Nat Methods. 2014; 11(4):381-383.
-
(2014)
Nat Methods
, vol.11
, Issue.4
, pp. 381-383
-
-
Rimm, DL.1
-
15
-
-
84926336637
-
Quantitative measurement of cancer tissue biomarkers in the lab and in the clinic
-
Carvajal-Hausdorf DE, Schalper KA, Neumeister VM, Rimm DL. Quantitative measurement of cancer tissue biomarkers in the lab and in the clinic. Lab Invest. 2015; 95(4):385-396.
-
(2015)
Lab Invest
, vol.95
, Issue.4
, pp. 385-396
-
-
Carvajal-Hausdorf, DE1
Schalper, KA2
Neumeister, VM3
Rimm, DL.4
-
16
-
-
33749867157
-
Analyzing proteome topology and function by automated multidimensional fluorescence microscopy
-
Schubert W, et al. Analyzing proteome topology and function by automated multidimensional fluorescence microscopy. Nat Biotechnol. 2006; 24(10):1270-1278.
-
(2006)
Nat Biotechnol
, vol.24
, Issue.10
, pp. 1270-1278
-
-
Schubert, W1
-
17
-
-
84880357794
-
Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue
-
Gerdes MJ, et al. Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue. Proc Natl Acad Sci U S A. 2013; 110(29):11982-11987.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.29
, pp. 11982-11987
-
-
Gerdes, MJ1
-
18
-
-
51049109033
-
Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/ mammalian target of rapamycin inhibitor with potent in vivo antitumor activity
-
Maira SM, et al. Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/ mammalian target of rapamycin inhibitor with potent in vivo antitumor activity. Mol Cancer Ther. 2008; 7(7):1851-1863.
-
(2008)
Mol Cancer Ther
, vol.7
, Issue.7
, pp. 1851-1863
-
-
Maira, SM1
-
19
-
-
77954331064
-
American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer (unabridged version)
-
Hammond ME, et al. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer (unabridged version). Arch Pathol Lab Med. 2010; 134(7):e48-e72.
-
(2010)
Arch Pathol Lab Med
, vol.134
, Issue.7
, pp. e48-e72
-
-
Hammond, ME1
-
20
-
-
84933278862
-
Clinical management of breast cancer heterogeneity
-
Zardavas D, Irrthum A, Swanton C, Piccart M. Clinical management of breast cancer heterogeneity. Nat Rev Clin Oncol. 2015; 12(7):381-394.
-
(2015)
Nat Rev Clin Oncol
, vol.12
, Issue.7
, pp. 381-394
-
-
Zardavas, D1
Irrthum, A2
Swanton, C3
Piccart, M.4
-
21
-
-
0038724494
-
Consensus clustering: a resampling-based method for class discovery and visualization of gene expression microarray data
-
Monti S, Tamayo P, Mesirov J, Golub T. Consensus clustering: a resampling-based method for class discovery and visualization of gene expression microarray data. Mach Learn. 2003; 52(1):91-118.
-
(2003)
Mach Learn
, vol.52
, Issue.1
, pp. 91-118
-
-
Monti, S1
Tamayo, P2
Mesirov, J3
Golub, T.4
-
22
-
-
77954182362
-
ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking
-
Wilkerson MD, Hayes DN. ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking. Bioinformatics. 2010; 26(12):1572-1573.
-
(2010)
Bioinformatics
, vol.26
, Issue.12
, pp. 1572-1573
-
-
Wilkerson, MD1
Hayes, DN.2
-
23
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou CM, et al. Molecular portraits of human breast tumours. Nature. 2000; 406(6797):747-752.
-
(2000)
Nature
, vol.406
, Issue.6797
, pp. 747-752
-
-
Perou, CM1
-
24
-
-
84906996719
-
How many etiological subtypes of breast cancer: two, three, four, or more?
-
Anderson WF, Rosenberg PS, Prat A, Perou CM, Sherman ME. How many etiological subtypes of breast cancer: two, three, four, or more? J Natl Cancer Inst. 2014; 106(8):dju165.
-
(2014)
J Natl Cancer Inst
, vol.106
, Issue.8
, pp. dju165
-
-
Anderson, WF1
Rosenberg, PS2
Prat, A3
Perou, CM4
Sherman, ME.5
-
25
-
-
84877028141
-
Comprehensive molecular portraits of human breast tumours
-
Cancer Genome Atlas N
-
Cancer Genome Atlas N. Comprehensive molecular portraits of human breast tumours. Nature. 2012; 490(7418):61-70.
-
(2012)
Nature
, vol.490
, Issue.7418
, pp. 61-70
-
-
-
26
-
-
84866002291
-
The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data
-
Cerami E, et al. The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov. 2012; 2(5):401-404.
-
(2012)
Cancer Discov
, vol.2
, Issue.5
, pp. 401-404
-
-
Cerami, E1
-
27
-
-
62449131093
-
Supervised risk predictor of breast cancer based on intrinsic subtypes
-
Parker JS, et al. Supervised risk predictor of breast cancer based on intrinsic subtypes. J Clin Oncol. 2009; 27(8):1160-1167.
-
(2009)
J Clin Oncol
, vol.27
, Issue.8
, pp. 1160-1167
-
-
Parker, JS1
-
28
-
-
84964314036
-
Standardized uptake value of (1)(8)F-fluorodeoxyglucose positron emission tomography for prediction of tumor recurrence in breast cancer beyond tumor burden
-
Ahn SG, et al. Standardized uptake value of (1)(8)F-fluorodeoxyglucose positron emission tomography for prediction of tumor recurrence in breast cancer beyond tumor burden. Breast Cancer Res. 2014; 16(6):502.
-
(2014)
Breast Cancer Res
, vol.16
, Issue.6
, pp. 502
-
-
Ahn, SG1
-
29
-
-
84912100879
-
SGK3 mediates INPP4B-dependent PI3K signaling in breast cancer
-
Gasser JA, Inuzuka H, Lau AW, Wei W, Beroukhim R, Toker A. SGK3 mediates INPP4B-dependent PI3K signaling in breast cancer. Mol Cell. 2014; 56(4):595-607.
-
(2014)
Mol Cell
, vol.56
, Issue.4
, pp. 595-607
-
-
Gasser, JA1
Inuzuka, H2
Lau, AW3
Wei, W4
Beroukhim, R5
Toker, A.6
-
30
-
-
3242676299
-
GLUT1 expression in tissue and (18)F-FDG uptake
-
Avril N. GLUT1 expression in tissue and (18)F-FDG uptake. J Nucl Med. 2004; 45(6):930-932.
-
(2004)
J Nucl Med
, vol.45
, Issue.6
, pp. 930-932
-
-
Avril, N.1
-
31
-
-
81155133281
-
Prognostic value of a combined estrogen receptor, progesterone receptor, Ki-67, and human epidermal growth factor receptor 2 immunohistochemical score and comparison with the Genomic Health recurrence score in early breast cancer
-
Cuzick J, et al. Prognostic value of a combined estrogen receptor, progesterone receptor, Ki-67, and human epidermal growth factor receptor 2 immunohistochemical score and comparison with the Genomic Health recurrence score in early breast cancer. J Clin Oncol. 2011; 29(32):4273-4278.
-
(2011)
J Clin Oncol
, vol.29
, Issue.32
, pp. 4273-4278
-
-
Cuzick, J1
-
32
-
-
33749143839
-
Multispectral imaging in biology and medicine: slices of life
-
Levenson RM, Mansfield JR. Multispectral imaging in biology and medicine: slices of life. Cytometry A. 2006; 69(8):748-758.
-
(2006)
Cytometry A
, vol.69
, Issue.8
, pp. 748-758
-
-
Levenson, RM1
Mansfield, JR.2
-
33
-
-
0036852721
-
Automated subcellular localization and quantification of protein expression in tissue microarrays
-
Camp RL, Chung GG, Rimm DL. Automated subcellular localization and quantification of protein expression in tissue microarrays. Nat Med. 2002; 8(11):1323-1327.
-
(2002)
Nat Med
, vol.8
, Issue.11
, pp. 1323-1327
-
-
Camp, RL1
Chung, GG2
Rimm, DL.3
-
34
-
-
84926342669
-
Immunohistochemistry and mass spectrometry for highly multiplexed cellular molecular imaging
-
Levenson RM, Borowsky AD, Angelo M. Immunohistochemistry and mass spectrometry for highly multiplexed cellular molecular imaging. Lab Invest. 2015; 95(4):397-405.
-
(2015)
Lab Invest
, vol.95
, Issue.4
, pp. 397-405
-
-
Levenson, RM1
Borowsky, AD2
Angelo, M.3
-
35
-
-
84953251229
-
Proteomic maps of breast cancer subtypes
-
Tyanova S, Albrechtsen R, Kronqvist P, Cox J, Mann M, Geiger T. Proteomic maps of breast cancer subtypes. Nat Commun. 2016; 7:10259.
-
(2016)
Nat Commun
, vol.7
, pp. 10259
-
-
Tyanova, S1
Albrechtsen, R2
Kronqvist, P3
Cox, J4
Mann, M5
Geiger, T.6
-
36
-
-
77949809850
-
Molecular analysis reveals a genetic basis for the phenotypic diversity of metaplastic breast carcinomas
-
Geyer FC, et al. Molecular analysis reveals a genetic basis for the phenotypic diversity of metaplastic breast carcinomas. J Pathol. 2010; 220(5):562-573.
-
(2010)
J Pathol
, vol.220
, Issue.5
, pp. 562-573
-
-
Geyer, FC1
-
37
-
-
74949101897
-
Inferring tumor progression from genomic heterogeneity
-
Navin N, et al. Inferring tumor progression from genomic heterogeneity. Genome Res. 2010; 20(1):68-80.
-
(2010)
Genome Res
, vol.20
, Issue.1
, pp. 68-80
-
-
Navin, N1
-
38
-
-
79953766940
-
Tumour evolution inferred by single-cell sequencing
-
Navin N, et al. Tumour evolution inferred by single-cell sequencing. Nature. 2011; 472(7341):90-94.
-
(2011)
Nature
, vol.472
, Issue.7341
, pp. 90-94
-
-
Navin, N1
-
39
-
-
84941201227
-
A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity
-
Waclaw B, Bozic I, Pittman ME, Hruban RH, Vogelstein B, Nowak MA. A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity. Nature. 2015; 525(7568):261-264.
-
(2015)
Nature
, vol.525
, Issue.7568
, pp. 261-264
-
-
Waclaw, B1
Bozic, I2
Pittman, ME3
Hruban, RH4
Vogelstein, B5
Nowak, MA.6
-
40
-
-
84942987073
-
In situ single-cell analysis identifies heterogeneity for PIK3CA mutation and HER2 amplification in HER2-positive breast cancer
-
Janiszewska M, et al. In situ single-cell analysis identifies heterogeneity for PIK3CA mutation and HER2 amplification in HER2-positive breast cancer. Nat Genet. 2015; 47(10):1212-1219.
-
(2015)
Nat Genet
, vol.47
, Issue.10
, pp. 1212-1219
-
-
Janiszewska, M1
-
41
-
-
39749083963
-
Comparison of triple-negative and estrogen receptor-positive/progesterone receptor-positive/HER2-negative breast carcinoma using quantitative fluorine-18 fluorodeoxyglucose/positron emission tomography imaging parameters: a potentially useful method for disease characterization
-
Basu S, et al. Comparison of triple-negative and estrogen receptor-positive/progesterone receptor-positive/HER2-negative breast carcinoma using quantitative fluorine-18 fluorodeoxyglucose/positron emission tomography imaging parameters: a potentially useful method for disease characterization. Cancer. 2008; 112(5):995-1000.
-
(2008)
Cancer
, vol.112
, Issue.5
, pp. 995-1000
-
-
Basu, S1
-
42
-
-
79960954452
-
18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancers
-
Palaskas N, et al. 18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancers. Cancer Res. 2011; 71(15):5164-5174.
-
(2011)
Cancer Res
, vol.71
, Issue.15
, pp. 5164-5174
-
-
Palaskas, N1
-
43
-
-
73349118491
-
PTEN dosage is essential for neurofibroma development and malignant transformation
-
Gregorian C, et al. PTEN dosage is essential for neurofibroma development and malignant transformation. Proc Natl Acad Sci U S A. 2009; 106(46):19479-19484.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.46
, pp. 19479-19484
-
-
Gregorian, C1
-
44
-
-
84859215796
-
Systemic elevation of PTEN induces a tumor-suppressive metabolic state
-
Garcia-Cao I, et al. Systemic elevation of PTEN induces a tumor-suppressive metabolic state. Cell. 2012; 149(1):49-62.
-
(2012)
Cell
, vol.149
, Issue.1
, pp. 49-62
-
-
Garcia-Cao, I1
-
45
-
-
37549020704
-
Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair
-
Saal LH, et al. Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair. Nat Genet. 2008; 40(1):102-107.
-
(2008)
Nat Genet
, vol.40
, Issue.1
, pp. 102-107
-
-
Saal, LH1
|