-
1
-
-
84938823530
-
Initial use of ambrisentan plus tadalafil in pulmonary arterial hypertension
-
x-wiley/crsRef/16156698
-
Galie N, Barbera JA, Frost AE, Ghofrani HA, Hoeper MM, McLaughlin VV, et al. Initial use of ambrisentan plus tadalafil in pulmonary arterial hypertension. New England Journal of Medicine 2015;373(9):834-44. x-wiley/crsRef/16156698 [DOI: 10.1056/NEJMoa1413687]
-
(2015)
New England Journal of Medicine
, vol.373
, Issue.9
, pp. 834-844
-
-
Galie, N.1
Barbera, J.A.2
Frost, A.E.3
Ghofrani, H.A.4
Hoeper, M.M.5
McLaughlin, V.V.6
-
2
-
-
46449124591
-
Ambrisentan for the treatment of pulmonary arterial hypertension: results of the ambrisentan in pulmonary arterial hypertension, randomized, double-blind, placebo-controlled, multicenter, efficacy (ARIES) study 1 and 2
-
x-wiley/crsRef/3192571
-
Galiè N, Olschewski H, Oudiz RJ, Torres F, Frost A, Ghofrani HA, et al. Ambrisentan for the treatment of pulmonary arterial hypertension: results of the ambrisentan in pulmonary arterial hypertension, randomized, double-blind, placebo-controlled, multicenter, efficacy (ARIES) study 1 and 2. Circulation 2008;117(23):3010-9. x-wiley/crsRef/3192571
-
(2008)
Circulation
, vol.117
, Issue.23
, pp. 3010-3019
-
-
Galiè, N.1
Olschewski, H.2
Oudiz, R.J.3
Torres, F.4
Frost, A.5
Ghofrani, H.A.6
-
3
-
-
85103123424
-
Letairis (Ambrisentan) Tablets: Medical Review(s)
-
(accessed prior to 10 March 2020)., x-wiley/crsRef/3192572
-
US Food and Drug Administration Center for Drug Evaluation and Research. Letairis (Ambrisentan) Tablets: Medical Review(s). www.accessdata.fda.gov/drugsatfda_docs/nda/2019/022081Orig1s039.pdf (accessed prior to 10 March 2020). x-wiley/crsRef/3192572
-
www.accessdata.fda.gov/drugsatfda_docs/nda/2019/022081Orig1s039.pdf
-
-
-
4
-
-
46449124591
-
Ambrisentan for the treatment of pulmonary arterial hypertension: results of the ambrisentan in pulmonary arterial hypertension, randomized, double-blind, placebo-controlled, multicenter, efficacy (ARIES) study 1 and 2
-
x-wiley/crsRef/3192574
-
Galiè N, Olschewski H, Oudiz RJ, Torres F, Frost A, Ghofrani HA, et al. Ambrisentan for the treatment of pulmonary arterial hypertension: results of the ambrisentan in pulmonary arterial hypertension, randomized, double-blind, placebo-controlled, multicenter, efficacy (ARIES) study 1 and 2. Circulation 2008;117(23):3010-9. x-wiley/crsRef/3192574
-
(2008)
Circulation
, vol.117
, Issue.23
, pp. 3010-3019
-
-
Galiè, N.1
Olschewski, H.2
Oudiz, R.J.3
Torres, F.4
Frost, A.5
Ghofrani, H.A.6
-
5
-
-
0037149718
-
Bosentan therapy for pulmonary arterial hypertension
-
x-wiley/crsRef/3192579
-
Rubin LJ, Badesch DB, Barst RJ, Galiè N, Black CM, Keogh A. Bosentan therapy for pulmonary arterial hypertension. New England Journal of Medicine 2002;346(12):896-903. x-wiley/crsRef/3192579
-
(2002)
New England Journal of Medicine
, vol.346
, Issue.12
, pp. 896-903
-
-
Rubin, L.J.1
Badesch, D.B.2
Barst, R.J.3
Galiè, N.4
Black, C.M.5
Keogh, A.6
-
6
-
-
85103114365
-
Tracleer (Bosentan) Tablets: Medical Review(s)
-
(accessed prior to 12 March 2020)., x-wiley/crsRef/3192580
-
US Food and Drug Administration Center for Drug Evaluation and Research. Tracleer (Bosentan) Tablets: Medical Review(s). www.accessdata.fda.gov/drugsatfda_docs/nda/2001/21-290_Tracleer.cfm (accessed prior to 12 March 2020). x-wiley/crsRef/3192580
-
www.accessdata.fda.gov/drugsatfda_docs/nda/2001/21-290_Tracleer.cfm
-
-
-
7
-
-
4544383466
-
Combination of bosentan with epoprostenol in pulmonary arterial hypertension: BREATHE-2
-
x-wiley/crsRef/3192582
-
Humbert M, Barst RJ, Robbins IM, Channick RN, Galiè N, Boonstra A, et al. Combination of bosentan with epoprostenol in pulmonary arterial hypertension: BREATHE-2. European Respiratory Journal 2004;24(3):353-9. x-wiley/crsRef/3192582
-
(2004)
European Respiratory Journal
, vol.24
, Issue.3
, pp. 353-359
-
-
Humbert, M.1
Barst, R.J.2
Robbins, I.M.3
Channick, R.N.4
Galiè, N.5
Boonstra, A.6
-
8
-
-
85103114365
-
Tracleer (Bosentan) Tablets: Medical Review(s)
-
(accessed prior to 12 March 2020)., x-wiley/crsRef/3192583
-
US Food and Drug Administration Center for Drug Evaluation and Research. Tracleer (Bosentan) Tablets: Medical Review(s). www.accessdata.fda.gov/drugsatfda_docs/nda/2001/21-290_Tracleer.cfm (accessed prior to 12 March 2020). x-wiley/crsRef/3192583
-
www.accessdata.fda.gov/drugsatfda_docs/nda/2001/21-290_Tracleer.cfm
-
-
-
9
-
-
33746206340
-
Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study
-
x-wiley/crsRef/3192585
-
Galiè N, Beghetti M, Gatzoulis MA, Granton J, Berger RM, Lauer A, et al. Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study. Circulation 2006;114(1):48-54. x-wiley/crsRef/3192585
-
(2006)
Circulation
, vol.114
, Issue.1
, pp. 48-54
-
-
Galiè, N.1
Beghetti, M.2
Gatzoulis, M.A.3
Granton, J.4
Berger, R.M.5
Lauer, A.6
-
10
-
-
0036263877
-
Complete results of the first randomized, placebo-controlled study of bosentan, a dual endothelin receptor antagonist, in pulmonary arterial hypertension
-
x-wiley/crsRef/3192587
-
Badesch DB, Bodin F, Channick RN, Frost A, Rainisio M, Robbins IM, et al. Complete results of the first randomized, placebo-controlled study of bosentan, a dual endothelin receptor antagonist, in pulmonary arterial hypertension. Current Therapeutic Research, Clinical and Experimental 2002;63(4):227-46. x-wiley/crsRef/3192587
-
(2002)
Current Therapeutic Research, Clinical and Experimental
, vol.63
, Issue.4
, pp. 227-246
-
-
Badesch, D.B.1
Bodin, F.2
Channick, R.N.3
Frost, A.4
Rainisio, M.5
Robbins, I.M.6
-
11
-
-
0035818316
-
Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study
-
x-wiley/crsRef/3192588
-
Channick RN, Simonneau G, Sitbon O, Robbins IM, Frost A, Tapson VF. Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study. Lancet 2001;358(9288):1119-23. x-wiley/crsRef/3192588
-
(2001)
Lancet
, vol.358
, Issue.9288
, pp. 1119-1123
-
-
Channick, R.N.1
Simonneau, G.2
Sitbon, O.3
Robbins, I.M.4
Frost, A.5
Tapson, V.F.6
-
12
-
-
84938903925
-
Bosentan added to sildenafil therapy in patients with pulmonary arterial hypertension
-
x-wiley/crsRef/16156700
-
McLaughlin V, Channick RN, Ghofrani HA, Lemarie JC, Naeije R, Packer M, et al. Bosentan added to sildenafil therapy in patients with pulmonary arterial hypertension. European Respiratory Journal 2015;46(2):405-13. x-wiley/crsRef/16156700 [DOI: 10.1183/13993003.02044-2014]
-
(2015)
European Respiratory Journal
, vol.46
, Issue.2
, pp. 405-413
-
-
McLaughlin, V.1
Channick, R.N.2
Ghofrani, H.A.3
Lemarie, J.C.4
Naeije, R.5
Packer, M.6
-
13
-
-
45249119855
-
Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): a double-blind, randomised controlled trial
-
x-wiley/crsRef/3192590
-
Galiè N, Rubin L, Hoeper M, Jansa P, Al-Hiti H, Meyer G, et al. Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): a double-blind, randomised controlled trial. Lancet 2008;371(9630):2093-100. x-wiley/crsRef/3192590
-
(2008)
Lancet
, vol.371
, Issue.9630
, pp. 2093-2100
-
-
Galiè, N.1
Rubin, L.2
Hoeper, M.3
Jansa, P.4
Al-Hiti, H.5
Meyer, G.6
-
14
-
-
85074143654
-
Early treatment with ambrisentan of mildly elevated mean pulmonary arterial pressure associated with systemic sclerosis: a randomized, controlled, double-blind, parallel group study (EDITA study)
-
x-wiley/crsRef/16156702
-
Pan Z, Marra AM, Benjamin N, Eichstaedt CA, Blank N, Bossone E, et al. Early treatment with ambrisentan of mildly elevated mean pulmonary arterial pressure associated with systemic sclerosis: a randomized, controlled, double-blind, parallel group study (EDITA study). Arthritis Research & Therapy 2019;21:217. x-wiley/crsRef/16156702
-
(2019)
Arthritis Research & Therapy
, vol.21
, pp. 217
-
-
Pan, Z.1
Marra, A.M.2
Benjamin, N.3
Eichstaedt, C.A.4
Blank, N.5
Bossone, E.6
-
15
-
-
0344837813
-
Effects of the oral endothelin-receptor antagonist bosentan on echocardiographic and doppler measures in patients with pulmonary arterial hypertension
-
x-wiley/crsRef/3192592
-
Galiè N, Hinderliter AL, Torbicki A, Fourme T, Simonneau G, Pulido T, et al. Effects of the oral endothelin-receptor antagonist bosentan on echocardiographic and doppler measures in patients with pulmonary arterial hypertension. Journal of the American College of Cardiology 2003;41(8):1380-6. x-wiley/crsRef/3192592
-
(2003)
Journal of the American College of Cardiology
, vol.41
, Issue.8
, pp. 1380-1386
-
-
Galiè, N.1
Hinderliter, A.L.2
Torbicki, A.3
Fourme, T.4
Simonneau, G.5
Pulido, T.6
-
16
-
-
85059241245
-
Evaluation of macitentan in patients with Eisenmenger Syndrome
-
x-wiley/crsRef/16156704
-
Gatzoulis MA, Landzberg M, Beghetti M, Berger RM, Efficace M, Gesang S, et al. Evaluation of macitentan in patients with Eisenmenger Syndrome. Circulation 2019;139(1):51-63. x-wiley/crsRef/16156704 [DOI: 10.1161/CIRCULATIONAHA.118.033575]
-
(2019)
Circulation
, vol.139
, Issue.1
, pp. 51-63
-
-
Gatzoulis, M.A.1
Landzberg, M.2
Beghetti, M.3
Berger, R.M.4
Efficace, M.5
Gesang, S.6
-
17
-
-
85062426851
-
Efficacy and safety of macitentan in patients with portopulmonary hypertension: the randomized, placebo controlled portico trial
-
x-wiley/crsRef/16156706
-
Krowka MJ, Cottreel E, De Groote P, Hoeper MM, Kim N, Martin N, et al. Efficacy and safety of macitentan in patients with portopulmonary hypertension: the randomized, placebo controlled portico trial. Hepatology. Conference 2018;Suppl 1:70A-71. x-wiley/crsRef/16156706 [DOI: 10.1002/hep.30256]
-
(2018)
Hepatology. Conference
, vol.Suppl 1
, pp. 70A-71
-
-
Krowka, M.J.1
Cottreel, E.2
De Groote, P.3
Hoeper, M.M.4
Kim, N.5
Martin, N.6
-
18
-
-
85067648677
-
Macitentan for the treatment of portopulmonary hypertension (PORTICO): a multicentre, randomised, double-blind, placebo-controlled, phase 4 trial
-
x-wiley/crsRef/16156707
-
Sitbon O, Bosch J, Cottreel E, Csonka D, de Groote P, Hoeper MM, et al. Macitentan for the treatment of portopulmonary hypertension (PORTICO): a multicentre, randomised, double-blind, placebo-controlled, phase 4 trial. Lancet Respiratory Medicine 2019;7:594-604. x-wiley/crsRef/16156707
-
(2019)
Lancet Respiratory Medicine
, vol.7
, pp. 594-604
-
-
Sitbon, O.1
Bosch, J.2
Cottreel, E.3
Csonka, D.4
de Groote, P.5
Hoeper, M.M.6
-
19
-
-
21144437393
-
Sildenafil versus endothelin receptor antagonist for pulmonary hypertension (SERAPH) study
-
x-wiley/crsRef/3192594
-
Wilkins MR, Paul GA, Strange JW, Tunariu N, Gin-Sing W, Banya WA, et al. Sildenafil versus endothelin receptor antagonist for pulmonary hypertension (SERAPH) study. American Journal of Respiratory and Critical Care Medicine 2005;171(11):1292-7. x-wiley/crsRef/3192594
-
(2005)
American Journal of Respiratory and Critical Care Medicine
, vol.171
, Issue.11
, pp. 1292-1297
-
-
Wilkins, M.R.1
Paul, G.A.2
Strange, J.W.3
Tunariu, N.4
Gin-Sing, W.5
Banya, W.A.6
-
20
-
-
84883108940
-
Macitentan and morbidity and mortality in pulmonary arterial hypertension
-
x-wiley/crsRef/16156709
-
Pulido T, Adzerikho I, Channick RN, Delcroix M, Galie N, Ghofrani HA, et al. Macitentan and morbidity and mortality in pulmonary arterial hypertension. New England Journal of Medicine 2013;369(9):809-18. x-wiley/crsRef/16156709 [DOI: 10.1056/NEJMoa1213917]
-
(2013)
New England Journal of Medicine
, vol.369
, Issue.9
, pp. 809-818
-
-
Pulido, T.1
Adzerikho, I.2
Channick, R.N.3
Delcroix, M.4
Galie, N.5
Ghofrani, H.A.6
-
21
-
-
10744230817
-
Sitaxsentan therapy for pulmonary arterial hypertension
-
x-wiley/crsRef/3192596
-
Barst RJ, Langleben D, Frost E, Horn EM, Oudiz R, Shapiro S, et al. Sitaxsentan therapy for pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine 2004;169:441-7. x-wiley/crsRef/3192596
-
(2004)
American Journal of Respiratory and Critical Care Medicine
, vol.169
, pp. 441-447
-
-
Barst, R.J.1
Langleben, D.2
Frost, E.3
Horn, E.M.4
Oudiz, R.5
Shapiro, S.6
-
22
-
-
85103126744
-
European Medicines Agency. EPARs for authorised medicinal products for human use: Thelin. European Public Assessment Report
-
(accessed 22 March 2008)., x-wiley/crsRef/3192597
-
European Medicines Agency. EPARs for authorised medicinal products for human use: Thelin. European Public Assessment Report. www.emea.europa.eu/humandocs/PDFs/EPAR/thelin/H-679-en6.pdf (accessed 22 March 2008). x-wiley/crsRef/3192597
-
www.emea.europa.eu/humandocs/PDFs/EPAR/thelin/H-679-en6.pdf
-
-
-
23
-
-
85103088095
-
Therapeutic Goods Administration (TGA), Australia. Public summary documents by product: Thelin
-
(accessed 25 April 2008)., x-wiley/crsRef/3192598
-
Therapeutic Goods Administration (TGA), Australia. Public summary documents by product: Thelin. www.health.gov.au/internet/main/publishing.nsf/Content/pbac-psd-sitaxentan-sodium-july07 (accessed 25 April 2008). x-wiley/crsRef/3192598
-
www.health.gov.au/internet/main/publishing.nsf/Content/pbac-psd-sitaxentan-sodium-july07
-
-
-
24
-
-
33646255654
-
Treatment of pulmonary arterial hypertension with the selective endothelin-A receptor antagonist sitaxsentan
-
x-wiley/crsRef/3192606
-
Barst RJ, Langleben D, Badesch D, Frost A, Lawrence EC, Shapiro S, et al. Treatment of pulmonary arterial hypertension with the selective endothelin-A receptor antagonist sitaxsentan. Journal of the American College of Cardiology 2006;47(10):2049-56. x-wiley/crsRef/3192606
-
(2006)
Journal of the American College of Cardiology
, vol.47
, Issue.10
, pp. 2049-2056
-
-
Barst, R.J.1
Langleben, D.2
Badesch, D.3
Frost, A.4
Lawrence, E.C.5
Shapiro, S.6
-
25
-
-
84872424105
-
European Medicines Agency. EPARs for authorised medicinal products for human use: Thelin. European Public Assessment Report
-
(accessed prior to 22 March 2020)., x-wiley/crsRef/3192607
-
European Medicines Agency. EPARs for authorised medicinal products for human use: Thelin. European Public Assessment Report. www.ema.europa.eu/en/medicines/human/EPAR/thelin (accessed prior to 22 March 2020). x-wiley/crsRef/3192607
-
www.ema.europa.eu/en/medicines/human/EPAR/thelin
-
-
-
26
-
-
85103088095
-
Therapeutic Goods Administration (TGA), Australia. Public summary documents by product: Thelin
-
(accessed 25 April 2008)., x-wiley/crsRef/3192608
-
Therapeutic Goods Administration (TGA), Australia. Public summary documents by product: Thelin. www.health.gov.au/internet/main/publishing.nsf/Content/pbac-psd-sitaxentan-sodium-july07 (accessed 25 April 2008). x-wiley/crsRef/3192608
-
www.health.gov.au/internet/main/publishing.nsf/Content/pbac-psd-sitaxentan-sodium-july07
-
-
-
27
-
-
84872424105
-
European Medicines Agency. EPARs for authorised medicinal products for human use: Thelin. European Public Assessment Report
-
(accessed 22 March 2008)., x-wiley/crsRef/3192618
-
European Medicines Agency. EPARs for authorised medicinal products for human use: Thelin. European Public Assessment Report. www.ema.europa.eu/en/medicines/human/EPAR/thelin (accessed 22 March 2008). x-wiley/crsRef/3192618
-
www.ema.europa.eu/en/medicines/human/EPAR/thelin
-
-
-
28
-
-
84907589926
-
Pharmacokinetic-pharmacodynamic relationships of macitentan, a new endothelin receptor antagonist, after multiple dosing in healthy Korean subjects
-
x-wiley/crsRef/16156711
-
Ahn LY, Kim SE, Yi S, Dingemanse J, Lim KS, Jang IJ, et al. Pharmacokinetic-pharmacodynamic relationships of macitentan, a new endothelin receptor antagonist, after multiple dosing in healthy Korean subjects. American Journal of Cardiovascular Drugs 2014;14(5):377-85. x-wiley/crsRef/16156711
-
(2014)
American Journal of Cardiovascular Drugs
, vol.14
, Issue.5
, pp. 377-385
-
-
Ahn, L.Y.1
Kim, S.E.2
Yi, S.3
Dingemanse, J.4
Lim, K.S.5
Jang, I.J.6
-
29
-
-
77950820615
-
Exercise capacity and haemodynamics inpatients with sickle cell disease with pulmonary hypertension treated with bosentan: results of the ASSET studies
-
x-wiley/crsRef/3192624
-
Barst RJ, Mubarak KK, Machado RF, Ataga KI, Benza RL, Castro O, et al. Exercise capacity and haemodynamics inpatients with sickle cell disease with pulmonary hypertension treated with bosentan: results of the ASSET studies. British Journal of Haematology 2010;149(3):426-35. x-wiley/crsRef/3192624
-
(2010)
British Journal of Haematology
, vol.149
, Issue.3
, pp. 426-435
-
-
Barst, R.J.1
Mubarak, K.K.2
Machado, R.F.3
Ataga, K.I.4
Benza, R.L.5
Castro, O.6
-
30
-
-
84880807894
-
Investigation of the effects of ketoconazole on the pharmacokinetics of macitentan, a novel dual endothelin receptor antagonist, in healthy subjects
-
x-wiley/crsRef/16156713
-
Atsmon J, Dingemanse J, Shaikevich D, Volokhov I, Sidharta PN. Investigation of the effects of ketoconazole on the pharmacokinetics of macitentan, a novel dual endothelin receptor antagonist, in healthy subjects. Clinical Pharmacokinetics 2013;52(8):685-92. x-wiley/crsRef/16156713 [DOI: 10.1007/s40262-013-0063-8]
-
(2013)
Clinical Pharmacokinetics
, vol.52
, Issue.8
, pp. 685-692
-
-
Atsmon, J.1
Dingemanse, J.2
Shaikevich, D.3
Volokhov, I.4
Sidharta, P.N.5
-
31
-
-
79955845135
-
Tadalafil monotherapy and as add-on to background bosentan in patients with pulmonary arterial hypertension
-
x-wiley/crsRef/3192626
-
Barst RJ, Oudiz RJ, Beardsworth A, Brundage BH, Simonneau G, Ghofrani HA, et al. Tadalafil monotherapy and as add-on to background bosentan in patients with pulmonary arterial hypertension. Journal of Heart and Lung Transplantation 2011;30(6):632-43. x-wiley/crsRef/3192626
-
(2011)
Journal of Heart and Lung Transplantation
, vol.30
, Issue.6
, pp. 632-643
-
-
Barst, R.J.1
Oudiz, R.J.2
Beardsworth, A.3
Brundage, B.H.4
Simonneau, G.5
Ghofrani, H.A.6
-
32
-
-
84898742360
-
Bosentan for sarcoidosis-associated pulmonary hypertension: a double-blind placebo controlled randomized trial
-
x-wiley/crsRef/16156715
-
Baughman RP, Culver DA, Cordova FC, Padilla M, Gibson KF, Lower EE, et al. Bosentan for sarcoidosis-associated pulmonary hypertension: a double-blind placebo controlled randomized trial. Chest 2014;145(4):810-7. x-wiley/crsRef/16156715
-
(2014)
Chest
, vol.145
, Issue.4
, pp. 810-817
-
-
Baughman, R.P.1
Culver, D.A.2
Cordova, F.C.3
Padilla, M.4
Gibson, K.F.5
Lower, E.E.6
-
33
-
-
33846247928
-
Sitaxsentan treatment for patients with pulmonary arterial hypertension discontinuing bosentan
-
x-wiley/crsRef/3192628
-
Benza RL, Mehta S, Keogh A, Lawrence EC, Oudiz RJ, Barst RJ. Sitaxsentan treatment for patients with pulmonary arterial hypertension discontinuing bosentan. Journal of Heart and Lung Transplantation 2007;26(1):63-9. x-wiley/crsRef/3192628
-
(2007)
Journal of Heart and Lung Transplantation
, vol.26
, Issue.1
, pp. 63-69
-
-
Benza, R.L.1
Mehta, S.2
Keogh, A.3
Lawrence, E.C.4
Oudiz, R.J.5
Barst, R.J.6
-
34
-
-
85103120131
-
Evaluation of the effect of ambrisentan on digital microvascular flow in patients with systemic sclerosis using laser doppler perfusion imaging
-
x-wiley/crsRef/16156717
-
Bose N, Bena J, Trunick C, Petrich J, Bork DJ, Krishnan G, et al. Evaluation of the effect of ambrisentan on digital microvascular flow in patients with systemic sclerosis using laser doppler perfusion imaging. Arthritis and Rheumatism 2011;63(10 Suppl 1):S276-7. x-wiley/crsRef/16156717
-
(2011)
Arthritis and Rheumatism
, vol.63
, Issue.10
, pp. S276-S277
-
-
Bose, N.1
Bena, J.2
Trunick, C.3
Petrich, J.4
Bork, D.J.5
Krishnan, G.6
-
35
-
-
84919639616
-
Multiple-dose up-titration study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of selexipag, an orally available selective prostacyclin receptor agonist, in healthy subjects
-
x-wiley/crsRef/16156719
-
Bruderer S, Hurst N, Kaufmann P, Dingemanse J. Multiple-dose up-titration study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of selexipag, an orally available selective prostacyclin receptor agonist, in healthy subjects. Pharmacology 2014;94(3-4):148-56. x-wiley/crsRef/16156719
-
(2014)
Pharmacology
, vol.94
, Issue.3-4
, pp. 148-156
-
-
Bruderer, S.1
Hurst, N.2
Kaufmann, P.3
Dingemanse, J.4
-
36
-
-
85103088920
-
Efficacy and safety of oral bosentan in pulmonary fibrosis associated with scleroderma
-
NCT00070590., (first received 8 October 2003)., x-wiley/crsRef/3192632
-
NCT00070590. Efficacy and safety of oral bosentan in pulmonary fibrosis associated with scleroderma. clinicaltrials.gov/ct2/show/NCT00070590 (first received 8 October 2003). x-wiley/crsRef/3192632
-
clinicaltrials.gov/ct2/show/NCT00070590
-
-
-
37
-
-
38049089932
-
Mutual pharmacokinetic interactions between steady-state bosentan and sildenafil
-
x-wiley/crsRef/16156721
-
Burgess G, Hoogkamer H, Collings L, Dingemanse J. Mutual pharmacokinetic interactions between steady-state bosentan and sildenafil. European Journal of Clinical Pharmacology 2008;64(1):43-50. x-wiley/crsRef/16156721
-
(2008)
European Journal of Clinical Pharmacology
, vol.64
, Issue.1
, pp. 43-50
-
-
Burgess, G.1
Hoogkamer, H.2
Collings, L.3
Dingemanse, J.4
-
38
-
-
85085605253
-
Bioequivalence and tolerability of ambrisentan: a pharmacokinetic study in Mexican healthy male subjects
-
x-wiley/crsRef/16156723
-
Cardenas KPC, Velazquez JER, Escobar JJO, Chirinos J, Pendela M. Bioequivalence and tolerability of ambrisentan: a pharmacokinetic study in Mexican healthy male subjects. European Journal of Drug Metabolism and Pharmacokinetics 2020;45:611-8. x-wiley/crsRef/16156723
-
(2020)
European Journal of Drug Metabolism and Pharmacokinetics
, vol.45
, pp. 611-618
-
-
Cardenas, K.P.C.1
Velazquez, J.E.R.2
Escobar, J.J.O.3
Chirinos, J.4
Pendela, M.5
-
39
-
-
85089984722
-
Efficacy and safety of initial triple oral versus initial double oral combination therapy in patients with newly diagnosed pulmonary arterial hypertension (PAH): results of the randomized controlled triton study
-
x-wiley/crsRef/16156725
-
Chin KM, Sitbon O, Doelberg M, Gibbs JSR, Hoeper MM, Martin N, et al. Efficacy and safety of initial triple oral versus initial double oral combination therapy in patients with newly diagnosed pulmonary arterial hypertension (PAH): results of the randomized controlled triton study. American Journal of Respiratory and Critical Care Medicine 2020;201:A2928. x-wiley/crsRef/16156725
-
(2020)
American Journal of Respiratory and Critical Care Medicine
, vol.201
, pp. A2928
-
-
Chin, K.M.1
Sitbon, O.2
Doelberg, M.3
Gibbs, J.S.R.4
Hoeper, M.M.5
Martin, N.6
-
41
-
-
85103117376
-
Efficacy and safety of various doses of the new dual endothelin receptor antagonist aprocitentan in the treatment of hypertension
-
x-wiley/crsRef/16156727
-
Danaietash P, Verweij P, Flamion B, Menard J, Bellet M. Efficacy and safety of various doses of the new dual endothelin receptor antagonist aprocitentan in the treatment of hypertension. European Heart Journal 2019;40(Suppl 1):ehz747.0004. x-wiley/crsRef/16156727
-
(2019)
European Heart Journal
, vol.40
-
-
Danaietash, P.1
Verweij, P.2
Flamion, B.3
Menard, J.4
Bellet, M.5
-
42
-
-
84888289239
-
Tezosentan and right ventricular failure in patients with pulmonary hypertension undergoing cardiac surgery: the TACTICS trial
-
x-wiley/crsRef/16156729
-
Denault AY, Pearl RG, Michler RE, Rao V, Tsui SS, Seitelberger R, et al. Tezosentan and right ventricular failure in patients with pulmonary hypertension undergoing cardiac surgery: the TACTICS trial. Journal of Cardiothoracic and Vascular Anesthesia 2013;27(6):1212-7. x-wiley/crsRef/16156729
-
(2013)
Journal of Cardiothoracic and Vascular Anesthesia
, vol.27
, Issue.6
, pp. 1212-1217
-
-
Denault, A.Y.1
Pearl, R.G.2
Michler, R.E.3
Rao, V.4
Tsui, S.S.5
Seitelberger, R.6
-
43
-
-
80051475258
-
Chronic selective endothelin a receptor antagonism reduces serum uric acid in hypertensive chronic kidney disease
-
x-wiley/crsRef/16156731
-
Dhaun N, Johnston NR, Goddard J, Webb DJ. Chronic selective endothelin a receptor antagonism reduces serum uric acid in hypertensive chronic kidney disease. Hypertension 2011;58(2):e11-2. x-wiley/crsRef/16156731
-
(2011)
Hypertension
, vol.58
, Issue.2
, pp. e11-e12
-
-
Dhaun, N.1
Johnston, N.R.2
Goddard, J.3
Webb, D.J.4
-
44
-
-
85067671969
-
Ambrisentan for treatment of inoperable chronic thromboembolic pulmonary hypertension (CTEPH)
-
x-wiley/crsRef/16156733
-
Escribano-Subias P, Bendjenana H, Curtis PS, Lang I, Vonk Noordegraaf A. Ambrisentan for treatment of inoperable chronic thromboembolic pulmonary hypertension (CTEPH). Pulmonary Circulation 2019;9(2):2045894019846433. x-wiley/crsRef/16156733 [DOI: 10.1177/2045894019846433]
-
(2019)
Pulmonary Circulation
, vol.9
, Issue.2
-
-
Escribano-Subias, P.1
Bendjenana, H.2
Curtis, P.S.3
Lang, I.4
Vonk Noordegraaf, A.5
-
45
-
-
65949118897
-
Bosentan decreases pulmonary vascular resistance and improves exercise capacity in acute hypoxia
-
x-wiley/crsRef/16156735
-
Faoro V, Boldingh S, Moreels M, Martinez S, Lamotte M, Unger P, et al. Bosentan decreases pulmonary vascular resistance and improves exercise capacity in acute hypoxia. Chest 2009;135(5):1215-22. x-wiley/crsRef/16156735
-
(2009)
Chest
, vol.135
, Issue.5
, pp. 1215-1222
-
-
Faoro, V.1
Boldingh, S.2
Moreels, M.3
Martinez, S.4
Lamotte, M.5
Unger, P.6
-
46
-
-
85056957561
-
Comparison of the efficacy of sildenafil alone versus sildenafil plus bosentan in newborns with persistent pulmonary hypertension
-
x-wiley/crsRef/16156737
-
Fatima N, Arshad S, Quddusi AI, Rehman A, Nadeem A, Iqbal I. Comparison of the efficacy of sildenafil alone versus sildenafil plus bosentan in newborns with persistent pulmonary hypertension. Journal of Ayub Medical College, Abbottabad 2018;30(3):333-6. x-wiley/crsRef/16156737
-
(2018)
Journal of Ayub Medical College, Abbottabad
, vol.30
, Issue.3
, pp. 333-336
-
-
Fatima, N.1
Arshad, S.2
Quddusi, A.I.3
Rehman, A.4
Nadeem, A.5
Iqbal, I.6
-
47
-
-
47549110195
-
Single-dose pharmacokinetics, pharmacodynamics, tolerability, and safety of the soluble guanylate cyclase stimulator BAY 63-2521: an ascending-dose study in healthy male volunteers
-
x-wiley/crsRef/3192646
-
Frey R, Muck W, Unger S, Artmeier-Brandt U, Weimann G, Wensing G. Single-dose pharmacokinetics, pharmacodynamics, tolerability, and safety of the soluble guanylate cyclase stimulator BAY 63-2521: an ascending-dose study in healthy male volunteers. Journal of Clinical Pharmacology 2008;48(8):926-34. x-wiley/crsRef/3192646
-
(2008)
Journal of Clinical Pharmacology
, vol.48
, Issue.8
, pp. 926-934
-
-
Frey, R.1
Muck, W.2
Unger, S.3
Artmeier-Brandt, U.4
Weimann, G.5
Wensing, G.6
-
48
-
-
22844436819
-
Ambrisentan therapy for pulmonary arterial hypertension
-
x-wiley/crsRef/16704619
-
Galiè N, Badesch D, Oudiz R, Simonneau G, McGoon MD, Keogh AM, et al. Ambrisentan therapy for pulmonary arterial hypertension. Journal of the American College of Cardiology 2005;46(3):529-35. x-wiley/crsRef/16704619
-
(2005)
Journal of the American College of Cardiology
, vol.46
, Issue.3
, pp. 529-535
-
-
Galiè, N.1
Badesch, D.2
Oudiz, R.3
Simonneau, G.4
McGoon, M.D.5
Keogh, A.M.6
-
49
-
-
67649523052
-
Tadalafil therapy for pulmonary arterial hypertension
-
x-wiley/crsRef/16704621
-
Galiè N, Brundage BH, Ghofrani HA, Oudiz RJ, Simonneau G, Safdar Z, et al. Tadalafil therapy for pulmonary arterial hypertension. Circulation 2009;119(22):2894-903. x-wiley/crsRef/16704621
-
(2009)
Circulation
, vol.119
, Issue.22
, pp. 2894-2903
-
-
Galiè, N.1
Brundage, B.H.2
Ghofrani, H.A.3
Oudiz, R.J.4
Simonneau, G.5
Safdar, Z.6
-
50
-
-
73449140681
-
3-year survival of patients treated with sitaxentan sodium (Thelin) for pulmonary arterial hypertension
-
x-wiley/crsRef/16704623
-
Galiè N, Naeije R, Burgess G, Dilleen M. 3-year survival of patients treated with sitaxentan sodium (Thelin) for pulmonary arterial hypertension. European Heart Journal 2009;Abstract Supplement:262. x-wiley/crsRef/16704623
-
(2009)
European Heart Journal
, vol.Abstract Supplement
, pp. 262
-
-
Galiè, N.1
Naeije, R.2
Burgess, G.3
Dilleen, M.4
-
51
-
-
84944617964
-
Effects of inhaled aviptadil (vasoactive intestinal peptide) in patients with pulmonary arterial hypertension (PAH): results from a phase II study
-
x-wiley/crsRef/3192654
-
Galiè N, Badesch D, Fleming T, Simonneau G, Rubin L, Ewert R, et al. Effects of inhaled aviptadil (vasoactive intestinal peptide) in patients with pulmonary arterial hypertension (PAH): results from a phase II study. European Heart Journal 2010;3122(Suppl 1):22, 347. x-wiley/crsRef/3192654
-
(2010)
European Heart Journal
, vol.3122
, pp. 22, 347
-
-
Galiè, N.1
Badesch, D.2
Fleming, T.3
Simonneau, G.4
Rubin, L.5
Ewert, R.6
-
52
-
-
78349237788
-
Long term use of imatinib In patients with severe pulmonary arterial hypertension [Abstract]
-
x-wiley/crsRef/3192656
-
Ghofrani HA, Morrell NW, Hoeper MM, Olschewski H, Peacock A, Barst RJ, et al. Long term use of imatinib In patients with severe pulmonary arterial hypertension [Abstract]. American Journal of Respiratory and Critical Care Medicine 2010;181:A2513. x-wiley/crsRef/3192656
-
(2010)
American Journal of Respiratory and Critical Care Medicine
, vol.181
, pp. A2513
-
-
Ghofrani, H.A.1
Morrell, N.W.2
Hoeper, M.M.3
Olschewski, H.4
Peacock, A.5
Barst, R.J.6
-
53
-
-
85028987452
-
Macitentan for the treatment of inoperable chronic thromboembolic pulmonary hypertension (MERIT-1): results from the multicentre, phase 2, randomised, double-blind, placebo-controlled study
-
x-wiley/crsRef/16156739
-
Ghofrani HA, Simonneau G, D'Armini AM, Fedullo P, Howard LS, Jais X, et al. Macitentan for the treatment of inoperable chronic thromboembolic pulmonary hypertension (MERIT-1): results from the multicentre, phase 2, randomised, double-blind, placebo-controlled study. Lancet Respiratory Medicine 2017;5(10):785-94. x-wiley/crsRef/16156739
-
(2017)
Lancet Respiratory Medicine
, vol.5
, Issue.10
, pp. 785-794
-
-
Ghofrani, H.A.1
Simonneau, G.2
D'Armini, A.M.3
Fedullo, P.4
Howard, L.S.5
Jais, X.6
-
55
-
-
85103083472
-
A placebo-controlled study of ambrisentan in subjects with idiopathic pulmonary fibrosis (ARTEMIS-IPF)
-
x-wiley/crsRef/16156741
-
Gillies H, Henig N, Pederson P, Shao L, Chien J, O'Riordan T, et al. A placebo-controlled study of ambrisentan in subjects with idiopathic pulmonary fibrosis (ARTEMIS-IPF). Life Sciences 2013;93(25-6):e59. x-wiley/crsRef/16156741
-
(2013)
Life Sciences
, vol.93
, Issue.25-6
-
-
Gillies, H.1
Henig, N.2
Pederson, P.3
Shao, L.4
Chien, J.5
O'Riordan, T.6
-
56
-
-
0034720820
-
Acute endothelin A receptor blockade causes selective pulmonary vasodilation in patients with chronic heart failure
-
x-wiley/crsRef/3192660
-
Givertz MM, Colucci WS, LeJemtel TH, Gottlieb SS, Hare JM, Slawsky MT, et al. Acute endothelin A receptor blockade causes selective pulmonary vasodilation in patients with chronic heart failure. Circulation 2000;101(25):2922-7. x-wiley/crsRef/3192660
-
(2000)
Circulation
, vol.101
, Issue.25
, pp. 2922-2927
-
-
Givertz, M.M.1
Colucci, W.S.2
LeJemtel, T.H.3
Gottlieb, S.S.4
Hare, J.M.5
Slawsky, M.T.6
-
57
-
-
85103087713
-
Efficacy and safety of sildenafil and atorvastatin added to bosentan as therapy for pulmonary arterial hypertension
-
[[A57] [Poster K18]], x-wiley/crsRef/3192662
-
Gomberg-Maitland M, McLaughlin V, Gulati M, Rich S, Arbor A. Efficacy and safety of sildenafil and atorvastatin added to bosentan as therapy for pulmonary arterial hypertension. In: American Thoracic Society 2005 International Conference; 2005 May 20-25; San Diego (CA). 2005. x-wiley/crsRef/3192662 [[A57] [Poster: K18]]
-
(2005)
American Thoracic Society 2005 International Conference; 2005 May 20-25; San Diego (CA)
-
-
Gomberg-Maitland, M.1
McLaughlin, V.2
Gulati, M.3
Rich, S.4
Arbor, A.5
-
58
-
-
85060804838
-
A randomized open label study comparing first-line treatment with bosentan or sildenafil in chronic thromboembolic pulmonary hypertension (CTEPH)
-
x-wiley/crsRef/16156743
-
Gotti E, Manes A, Palazzini M, Bernabe C, Bachetti C, Conficoni E, et al. A randomized open label study comparing first-line treatment with bosentan or sildenafil in chronic thromboembolic pulmonary hypertension (CTEPH). European Heart Journal 2014;35:208. x-wiley/crsRef/16156743
-
(2014)
European Heart Journal
, vol.35
, pp. 208
-
-
Gotti, E.1
Manes, A.2
Palazzini, M.3
Bernabe, C.4
Bachetti, C.5
Conficoni, E.6
-
59
-
-
77953795218
-
Lack of a pharmacokinetic interaction between oral treprostinil and bosentan in healthy adult volunteers
-
x-wiley/crsRef/3192664
-
Gotzkowsky SK, Dingemanse J, Lai A, Mottola D, Laliberte K. Lack of a pharmacokinetic interaction between oral treprostinil and bosentan in healthy adult volunteers. Journal of Clinical Pharmacology 2010;50(7):829-34. x-wiley/crsRef/3192664
-
(2010)
Journal of Clinical Pharmacology
, vol.50
, Issue.7
, pp. 829-834
-
-
Gotzkowsky, S.K.1
Dingemanse, J.2
Lai, A.3
Mottola, D.4
Laliberte, K.5
-
60
-
-
85103096210
-
Endothelin receptor blockade in heart failure with diastolic dysfunction and pulmonary hypertension
-
x-wiley/crsRef/16156745
-
Grander W, Koller K, Steringer-Mascherbauer R, Ebner CH. Endothelin receptor blockade in heart failure with diastolic dysfunction and pulmonary hypertension. European Heart Journal 2014;35:692. x-wiley/crsRef/16156745
-
(2014)
European Heart Journal
, vol.35
, pp. 692
-
-
Grander, W.1
Koller, K.2
Steringer-Mascherbauer, R.3
Ebner, C.H.4
-
61
-
-
85085552128
-
Bioequivalence of macitentan and tadalafil given as fixed-dose combination or single-component tablets in healthy subjects
-
x-wiley/crsRef/16156747
-
Grill S, Bruderer S, Sidharta PN, Antonova M, Globig S, Carlson J, et al. Bioequivalence of macitentan and tadalafil given as fixed-dose combination or single-component tablets in healthy subjects. British Journal of Clinical Pharmacology 2020;86(12):2424-34. x-wiley/crsRef/16156747
-
(2020)
British Journal of Clinical Pharmacology
, vol.86
, Issue.12
, pp. 2424-2434
-
-
Grill, S.1
Bruderer, S.2
Sidharta, P.N.3
Antonova, M.4
Globig, S.5
Carlson, J.6
-
62
-
-
84878790344
-
Relative bioavailability of a newly developed pediatric formulation of bosentan vs. the adult formulation
-
x-wiley/crsRef/16156749
-
Gutierrez MM, Nicolas LB, Donazzolo Y, Dingemanse J. Relative bioavailability of a newly developed pediatric formulation of bosentan vs. the adult formulation. International Journal of Clinical Pharmacology and Therapeutics 2013;51(6):529-36. x-wiley/crsRef/16156749
-
(2013)
International Journal of Clinical Pharmacology and Therapeutics
, vol.51
, Issue.6
, pp. 529-536
-
-
Gutierrez, M.M.1
Nicolas, L.B.2
Donazzolo, Y.3
Dingemanse, J.4
-
63
-
-
85031672110
-
Treatment of pulmonary arterial hypertension using initial combination therapy of bosentan and iloprost
-
x-wiley/crsRef/16156751
-
Han X, Zhang Y, Dong L, Fang L, Chai Y, Niu M, et al. Treatment of pulmonary arterial hypertension using initial combination therapy of bosentan and iloprost. Respiratory Care 2017;62(4):489-96. x-wiley/crsRef/16156751 [DOI: 10.4187/respcare.05280]
-
(2017)
Respiratory Care
, vol.62
, Issue.4
, pp. 489-496
-
-
Han, X.1
Zhang, Y.2
Dong, L.3
Fang, L.4
Chai, Y.5
Niu, M.6
-
64
-
-
85103099023
-
A double blind, randomized, controlled pharmacokinetic and pharmacodynamics trial of ambrisentan after Fontan surgery
-
x-wiley/crsRef/16156753
-
Hill KD, Maharaj A, Thompson E, Li JS, Pearson E, Hornik C. A double blind, randomized, controlled pharmacokinetic and pharmacodynamics trial of ambrisentan after Fontan surgery. Circulation 2018;138:A14968. x-wiley/crsRef/16156753
-
(2018)
Circulation
, vol.138
, pp. A14968
-
-
Hill, K.D.1
Maharaj, A.2
Thompson, E.3
Li, J.S.4
Pearson, E.5
Hornik, C.6
-
65
-
-
33847368988
-
Combining inhaled iloprost with bosentan in patients with idiopathic pulmonary arterial hypertension
-
x-wiley/crsRef/3192666
-
Hoeper MM, Leuchte H, Halank M, Wilkens H, Meyer FJ, Seyfarth HJ, et al. Combining inhaled iloprost with bosentan in patients with idiopathic pulmonary arterial hypertension. European Respiratory Journal 2006;28(4):691-4. x-wiley/crsRef/3192666
-
(2006)
European Respiratory Journal
, vol.28
, Issue.4
, pp. 691-694
-
-
Hoeper, M.M.1
Leuchte, H.2
Halank, M.3
Wilkens, H.4
Meyer, F.J.5
Seyfarth, H.J.6
-
66
-
-
85089804409
-
Long-term safety, tolerability and efficacy of macitentan in patients with inoperable chronic thromboembolic pulmonary hypertension: the merit-1 study and its open-label extension merit-2
-
x-wiley/crsRef/16156755
-
Howard LS, Ghofrani HA, D'Armini AM, Fedullo P, Gesang S, Jais X, et al. Long-term safety, tolerability and efficacy of macitentan in patients with inoperable chronic thromboembolic pulmonary hypertension: the merit-1 study and its open-label extension merit-2. In: American Journal of Respiratory and Critical Care Medicine. Vol. 201. 2019:A6068. x-wiley/crsRef/16156755
-
(2019)
American Journal of Respiratory and Critical Care Medicine
, vol.201
, pp. A6068
-
-
Howard, L.S.1
Ghofrani, H.A.2
D'Armini, A.M.3
Fedullo, P.4
Gesang, S.5
Jais, X.6
-
67
-
-
85048496260
-
Role of pulmonary hypertension and right ventricular dysfunction in aerobic exercise capacity limitation in normal volunteers at high altitude
-
x-wiley/crsRef/3192668
-
Huez S, Faoro V, Moreels M, Bastin R, Retailleau K, Lamotte M, et al. Role of pulmonary hypertension and right ventricular dysfunction in aerobic exercise capacity limitation in normal volunteers at high altitude. Acta Cardiologica 2009;64(1):114. x-wiley/crsRef/3192668
-
(2009)
Acta Cardiologica
, vol.64
, Issue.1
, pp. 114
-
-
Huez, S.1
Faoro, V.2
Moreels, M.3
Bastin, R.4
Retailleau, K.5
Lamotte, M.6
-
68
-
-
84952802205
-
Lack of pharmacokinetic interactions between macitentan and a combined oral contraceptive in healthy female subjects
-
x-wiley/crsRef/16156757
-
Hurst N, Pellek M, Dingemanse J, Sidharta PN. Lack of pharmacokinetic interactions between macitentan and a combined oral contraceptive in healthy female subjects. American College of Clinical Pharmacology 2016;56(6):669-74. x-wiley/crsRef/16156757
-
(2016)
American College of Clinical Pharmacology
, vol.56
, Issue.6
, pp. 669-674
-
-
Hurst, N.1
Pellek, M.2
Dingemanse, J.3
Sidharta, P.N.4
-
69
-
-
77952019637
-
Combination therapy with bosentan and sildenafil in Eisenmenger syndrome: a randomized, placebo-controlled, double-blinded trial
-
x-wiley/crsRef/3192670
-
Iversen K, Jensen AS, Jensen TV, Vejlstrup NG, Sondergaard L. Combination therapy with bosentan and sildenafil in Eisenmenger syndrome: a randomized, placebo-controlled, double-blinded trial. European Heart Journal 2010;31(9):1124-31. x-wiley/crsRef/3192670
-
(2010)
European Heart Journal
, vol.31
, Issue.9
, pp. 1124-1131
-
-
Iversen, K.1
Jensen, A.S.2
Jensen, T.V.3
Vejlstrup, N.G.4
Sondergaard, L.5
-
70
-
-
57449103127
-
Bosentan for treatment of inoperable chronic thromboembolic pulmonary hypertension: BENEFiT (Bosentan Effects in iNopErable Forms of chronIc Thromboembolic pulmonary hypertension), a randomized, placebo-controlled trial
-
x-wiley/crsRef/3192672
-
Jais X, D'Armini AM, Jansa P, Torbicki A, Delcroix M, Ghofrani HA, et al. Bosentan for treatment of inoperable chronic thromboembolic pulmonary hypertension: BENEFiT (Bosentan Effects in iNopErable Forms of chronIc Thromboembolic pulmonary hypertension), a randomized, placebo-controlled trial. Journal of the American College of Cardiology 2008;52(25):2127-34. x-wiley/crsRef/3192672
-
(2008)
Journal of the American College of Cardiology
, vol.52
, Issue.25
, pp. 2127-2134
-
-
Jais, X.1
D'Armini, A.M.2
Jansa, P.3
Torbicki, A.4
Delcroix, M.5
Ghofrani, H.A.6
-
71
-
-
0036774973
-
Do results of the ENABLE (Endothelin Antagonist Bosentan for Lowering Cardiac Events in Heart Failure) study spell the end for non-selective endothelin antagonism in heart failure?
-
x-wiley/crsRef/3192674
-
Kalra PR, Moon JC, Coats AJ. Do results of the ENABLE (Endothelin Antagonist Bosentan for Lowering Cardiac Events in Heart Failure) study spell the end for non-selective endothelin antagonism in heart failure? International Journal of Cardiology 2002;85(2-3):195-7. x-wiley/crsRef/3192674
-
(2002)
International Journal of Cardiology
, vol.85
, Issue.2-3
, pp. 195-197
-
-
Kalra, P.R.1
Moon, J.C.2
Coats, A.J.3
-
72
-
-
40149087049
-
Clinical and hemodynamic effects of bosentan dose optimization in symptomatic heart failure patients with severe systolic dysfunction, associated with secondary pulmonary hypertension - a multi-center randomized study
-
x-wiley/crsRef/16156759
-
Kaluski E, Cotter G, Leitman M, Milo-Cotter O, Krakover R, Kobrin I, et al. Clinical and hemodynamic effects of bosentan dose optimization in symptomatic heart failure patients with severe systolic dysfunction, associated with secondary pulmonary hypertension - a multi-center randomized study. Cardiology 2008;109(4):273-80. x-wiley/crsRef/16156759
-
(2008)
Cardiology
, vol.109
, Issue.4
, pp. 273-280
-
-
Kaluski, E.1
Cotter, G.2
Leitman, M.3
Milo-Cotter, O.4
Krakover, R.5
Kobrin, I.6
-
73
-
-
77950414996
-
A randomized, double-blind, placebo-controlled study of high-dose bosentan in patients with stage IV metastatic melanoma receiving first-line dacarbazine chemotherapy
-
x-wiley/crsRef/16156761
-
Kefford RF, Clingan PR, Brady B, Ballmer A, Morganti A, Hersey P. A randomized, double-blind, placebo-controlled study of high-dose bosentan in patients with stage IV metastatic melanoma receiving first-line dacarbazine chemotherapy. Molecular Cancer 2010;9:69. x-wiley/crsRef/16156761
-
(2010)
Molecular Cancer
, vol.9
, pp. 69
-
-
Kefford, R.F.1
Clingan, P.R.2
Brady, B.3
Ballmer, A.4
Morganti, A.5
Hersey, P.6
-
74
-
-
84999337013
-
Bosentan in pulmonary hypertension associated with fibrotic idiopathic interstitial pneumonia: a randomized, double-blind, placebo-controlled study
-
x-wiley/crsRef/16156763
-
Keir G, Corte T, Parfitt L, Maher T, Marino P, Renzoni E, et al. Bosentan in pulmonary hypertension associated with fibrotic idiopathic interstitial pneumonia: a randomized, double-blind, placebo-controlled study. European Respiratory Journal 2013;42:1179. x-wiley/crsRef/16156763
-
(2013)
European Respiratory Journal
, vol.42
, pp. 1179
-
-
Keir, G.1
Corte, T.2
Parfitt, L.3
Maher, T.4
Marino, P.5
Renzoni, E.6
-
75
-
-
85103079826
-
Non-invasive haemodynamic measurement to detect treatment response in pulmonary hypertension associated with fibrotic idiopathic interstitial pneumonia [Abstract]
-
x-wiley/crsRef/16156765
-
Keir G, Corte T, Dimopoulos K, Gatzoulis M, Marino P, Renzoni E, et al. Non-invasive haemodynamic measurement to detect treatment response in pulmonary hypertension associated with fibrotic idiopathic interstitial pneumonia [Abstract]. European Respiratory Journal 2014;44(Suppl 58):P2335. x-wiley/crsRef/16156765
-
(2014)
European Respiratory Journal
, vol.44
, pp. P2335
-
-
Keir, G.1
Corte, T.2
Dimopoulos, K.3
Gatzoulis, M.4
Marino, P.5
Renzoni, E.6
-
76
-
-
37849012578
-
BUILD-1: a randomized placebo-controlled trial of bosentan in idiopathic pulmonary fibrosis
-
King TE Jr,, x-wiley/crsRef/3192682
-
King TE Jr, Behr J, Brown KK, du Bois RM, Lancaster L, de Andrade JA, et al. BUILD-1: a randomized placebo-controlled trial of bosentan in idiopathic pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine 2008;177(1):75-81. x-wiley/crsRef/3192682
-
(2008)
American Journal of Respiratory and Critical Care Medicine
, vol.177
, Issue.1
, pp. 75-81
-
-
Behr, J.1
Brown, K.K.2
du Bois, R.M.3
Lancaster, L.4
de Andrade, J.A.5
-
77
-
-
0029087262
-
Evidence for endothelin-1-mediated vasoconstriction in severe chronic heart failure
-
x-wiley/crsRef/16156767
-
Kiowski W, Sutsch G, Hunziker P, Muller P, Kim J, Oechslin E, et al. Evidence for endothelin-1-mediated vasoconstriction in severe chronic heart failure. Lancet 1995;346(8977):732-6. x-wiley/crsRef/16156767
-
(1995)
Lancet
, vol.346
, Issue.8977
, pp. 732-736
-
-
Kiowski, W.1
Sutsch, G.2
Hunziker, P.3
Muller, P.4
Kim, J.5
Oechslin, E.6
-
78
-
-
85005939721
-
Pilot study of endothelin receptor blockade in heart failure with diastolic dysfunction and pulmonary hypertension (BADDHY-Trial)
-
x-wiley/crsRef/16156769
-
Koller B, Steringer-Mascherbauer R, Ebner CH, Weber T, Ammer M, Eichinger J, et al. Pilot study of endothelin receptor blockade in heart failure with diastolic dysfunction and pulmonary hypertension (BADDHY-Trial). Heart, Lung and Circulation 2017;26(5):433-41. x-wiley/crsRef/16156769
-
(2017)
Heart, Lung and Circulation
, vol.26
, Issue.5
, pp. 433-441
-
-
Koller, B.1
Steringer-Mascherbauer, R.2
Ebner, C.H.3
Weber, T.4
Ammer, M.5
Eichinger, J.6
-
79
-
-
10444270963
-
Digital ulcers in systemic sclerosis: prevention by treatment with bosentan, an oral endothelin receptor antagonist
-
x-wiley/crsRef/3192686
-
Korn JH, Mayes M, Matucci CM, Rainisio M, Pope J, Hachulla E, et al. Digital ulcers in systemic sclerosis: prevention by treatment with bosentan, an oral endothelin receptor antagonist. Arthritis and Rheumatism 2004;50(12):3985-93. x-wiley/crsRef/3192686
-
(2004)
Arthritis and Rheumatism
, vol.50
, Issue.12
, pp. 3985-3993
-
-
Korn, J.H.1
Mayes, M.2
Matucci, C.M.3
Rainisio, M.4
Pope, J.5
Hachulla, E.6
-
80
-
-
65549089130
-
Effects of pravastatin on functional capacity in patients with chronic obstructive pulmonary disease and pulmonary hypertension
-
x-wiley/crsRef/3192688
-
Lee TM, Chen CC, Shen HN, Chang NC. Effects of pravastatin on functional capacity in patients with chronic obstructive pulmonary disease and pulmonary hypertension. Clinical Science 2009;116(6):497-505. x-wiley/crsRef/3192688
-
(2009)
Clinical Science
, vol.116
, Issue.6
, pp. 497-505
-
-
Lee, T.M.1
Chen, C.C.2
Shen, H.N.3
Chang, N.C.4
-
81
-
-
84906935706
-
Macitentan, a dual endothelin receptor antagonist for the treatment of pulmonary arterial hypertension, does not affect cardiac repolarization in healthy subjects
-
x-wiley/crsRef/16156771
-
Lindegger N, Sidharta PN, Reseski K, Dingemanse J. Macitentan, a dual endothelin receptor antagonist for the treatment of pulmonary arterial hypertension, does not affect cardiac repolarization in healthy subjects. Pulmonary Pharmacology and Therapeutics 2014;29(1):41-8. x-wiley/crsRef/16156771
-
(2014)
Pulmonary Pharmacology and Therapeutics
, vol.29
, Issue.1
, pp. 41-48
-
-
Lindegger, N.1
Sidharta, P.N.2
Reseski, K.3
Dingemanse, J.4
-
82
-
-
84887330731
-
A randomized open label study comparing first-line treatment with bosentan or sildenafil in pulmonary arterial hypertension (PAH): long-term results
-
x-wiley/crsRef/16156773
-
Mazzanti G, Palazzini M, Leci E, Dardi F, Rinaldi A, D'Adamo A, et al. A randomized open label study comparing first-line treatment with bosentan or sildenafil in pulmonary arterial hypertension (PAH): long-term results. American Journal of Respiratory and Critical Care Medicine 2013;187:A3535. x-wiley/crsRef/16156773
-
(2013)
American Journal of Respiratory and Critical Care Medicine
, vol.187
, pp. A3535
-
-
Mazzanti, G.1
Palazzini, M.2
Leci, E.3
Dardi, F.4
Rinaldi, A.5
D'Adamo, A.6
-
83
-
-
12244251412
-
Efficacy and safety of treprostinil: an epoprostenol analog for primary pulmonary hypertension
-
x-wiley/crsRef/3192690
-
McLaughlin VV, Gaine SP, Barst RJ, Oudiz RJ, Bourge RC, Frost A, et al. Efficacy and safety of treprostinil: an epoprostenol analog for primary pulmonary hypertension. Journal of Cardiovascular Pharmacology 2003;41(2):293-9. x-wiley/crsRef/3192690
-
(2003)
Journal of Cardiovascular Pharmacology
, vol.41
, Issue.2
, pp. 293-299
-
-
McLaughlin, V.V.1
Gaine, S.P.2
Barst, R.J.3
Oudiz, R.J.4
Bourge, R.C.5
Frost, A.6
-
84
-
-
33845526777
-
Randomized study of adding inhaled iloprost to existing bosentan in pulmonary arterial hypertension
-
x-wiley/crsRef/3192692
-
McLaughlin VV, Oudiz RJ, Frost A, Tapson VF, Murali S, Channick RN, et al. Randomized study of adding inhaled iloprost to existing bosentan in pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine 2006;174(11):1257-63. x-wiley/crsRef/3192692
-
(2006)
American Journal of Respiratory and Critical Care Medicine
, vol.174
, Issue.11
, pp. 1257-1263
-
-
McLaughlin, V.V.1
Oudiz, R.J.2
Frost, A.3
Tapson, V.F.4
Murali, S.5
Channick, R.N.6
-
85
-
-
77952301237
-
Addition of inhaled treprostinil to oral therapy for pulmonary arterial hypertension: a randomized controlled clinical trial
-
x-wiley/crsRef/3192694
-
McLaughlin VV, Benza RL, Rubin LJ, Channick RN, Voswinckel R, Tapson VF, et al. Addition of inhaled treprostinil to oral therapy for pulmonary arterial hypertension: a randomized controlled clinical trial. Journal of the American College of Cardiology 2010;55(18):1915-22. x-wiley/crsRef/3192694
-
(2010)
Journal of the American College of Cardiology
, vol.55
, Issue.18
, pp. 1915-1922
-
-
McLaughlin, V.V.1
Benza, R.L.2
Rubin, L.J.3
Channick, R.N.4
Voswinckel, R.5
Tapson, V.F.6
-
86
-
-
33749525364
-
Exercise and respiratory training improve exercise capacity and quality of life in patients with severe chronic pulmonary hypertension
-
x-wiley/crsRef/3192696
-
Mereles D, Ehlken N, Kreuscher S, Ghofrani S, Hoeper MM, Halank M, et al. Exercise and respiratory training improve exercise capacity and quality of life in patients with severe chronic pulmonary hypertension. Circulation 2006;114(14):1482-9. x-wiley/crsRef/3192696
-
(2006)
Circulation
, vol.114
, Issue.14
, pp. 1482-1489
-
-
Mereles, D.1
Ehlken, N.2
Kreuscher, S.3
Ghofrani, S.4
Hoeper, M.M.5
Halank, M.6
-
87
-
-
85103129136
-
The effect of the ET-1 receptor antagonist, bosentan, on patients with poorly controlled asthma: a 17 week, double-blind, placebo-controlled crossover pilot study
-
x-wiley/crsRef/16156775
-
Metersky M, Coyle T. The effect of the ET-1 receptor antagonist, bosentan, on patients with poorly controlled asthma: a 17 week, double-blind, placebo-controlled crossover pilot study. Chest 2011;140(4):919A. x-wiley/crsRef/16156775
-
(2011)
Chest
, vol.140
, Issue.4
, pp. 919A
-
-
Metersky, M.1
Coyle, T.2
-
88
-
-
33749028972
-
Role of endothelin-1 in exposure to high altitude: Acute Mountain Sickness and Endothelin-1 (ACME-1) study
-
x-wiley/crsRef/3192698
-
Modesti PA, Vanni S, Morabito M, Modesti A, Marchetta M, Gamberi T, et al. Role of endothelin-1 in exposure to high altitude: Acute Mountain Sickness and Endothelin-1 (ACME-1) study. Circulation 2006;114(13):1410-6. x-wiley/crsRef/3192698
-
(2006)
Circulation
, vol.114
, Issue.13
, pp. 1410-1416
-
-
Modesti, P.A.1
Vanni, S.2
Morabito, M.3
Modesti, A.4
Marchetta, M.5
Gamberi, T.6
-
89
-
-
78349257100
-
Pulmonary artery pressure limits exercise capacity at high altitude
-
x-wiley/crsRef/16156777
-
Naeije R, Huez S, Lamotte M, Retailleau K, Neupane S, Abramowicz D, et al. Pulmonary artery pressure limits exercise capacity at high altitude. European Respiratory Journal 2010;36(5):1049-55. x-wiley/crsRef/16156777
-
(2010)
European Respiratory Journal
, vol.36
, Issue.5
, pp. 1049-1055
-
-
Naeije, R.1
Huez, S.2
Lamotte, M.3
Retailleau, K.4
Neupane, S.5
Abramowicz, D.6
-
90
-
-
79551633577
-
Pharmacokinetics of ambrisentan, a novel drug for treatment of Pulmonary Arterial Hypertension (PAH), in Japanese subjects
-
x-wiley/crsRef/3192702
-
Nakahara N, Wakamatsu A, Shimamura R, Nohda S, Miki S, Hirama T. Pharmacokinetics of ambrisentan, a novel drug for treatment of Pulmonary Arterial Hypertension (PAH), in Japanese subjects. Japanese Journal of Clinical Pharmacology and Therapeutics 2010;41(6):301-8. x-wiley/crsRef/3192702
-
(2010)
Japanese Journal of Clinical Pharmacology and Therapeutics
, vol.41
, Issue.6
, pp. 301-308
-
-
Nakahara, N.1
Wakamatsu, A.2
Shimamura, R.3
Nohda, S.4
Miki, S.5
Hirama, T.6
-
91
-
-
85103089665
-
Efficacy and safety of oral bosentan on healing/prevention of digital (finger) ulcers in patients with scleroderma patients (RAPIDS-2)
-
NCT00077584., [A randomized, double-blind, placebo-controlled, multi-center study to assess the effect of bosentan on healing and prevention of ischemic digital ulcers in patients with systemic sclerosis]., (first received 11 February 2004)., x-wiley/crsRef/16704625
-
NCT00077584. Efficacy and safety of oral bosentan on healing/prevention of digital (finger) ulcers in patients with scleroderma patients (RAPIDS-2) [A randomized, double-blind, placebo-controlled, multi-center study to assess the effect of bosentan on healing and prevention of ischemic digital ulcers in patients with systemic sclerosis]. clinicaltrials.gov/ct2/show/NCT00077584 (first received 11 February 2004). x-wiley/crsRef/16704625
-
clinicaltrials.gov/ct2/show/NCT00077584
-
-
-
92
-
-
85064992673
-
A phase I study to show the relative bioavailability and bioequivalence of fixed-dose combinations of ambrisentan and tadalafil in healthy subjects
-
x-wiley/crsRef/16156779
-
Okour M, Puri A, Chen G, Port K, Berni A, Khindri S, et al. A phase I study to show the relative bioavailability and bioequivalence of fixed-dose combinations of ambrisentan and tadalafil in healthy subjects. Clinical Therapeutics 2019;41:1110-27. x-wiley/crsRef/16156779
-
(2019)
Clinical Therapeutics
, vol.41
, pp. 1110-1127
-
-
Okour, M.1
Puri, A.2
Chen, G.3
Port, K.4
Berni, A.5
Khindri, S.6
-
93
-
-
44349149660
-
Long-term ambrisentan therapy provides sustained benefit in patients with pulmonary arterial hypertension
-
x-wiley/crsRef/3192704
-
Oudiz RJ. Long-term ambrisentan therapy provides sustained benefit in patients with pulmonary arterial hypertension. Chest 2007;132(4):474a. x-wiley/crsRef/3192704
-
(2007)
Chest
, vol.132
, Issue.4
, pp. 474a
-
-
Oudiz, R.J.1
-
94
-
-
70350708667
-
Long-term ambrisentan therapy for the treatment of pulmonary arterial hypertension
-
x-wiley/crsRef/3192706
-
Oudiz RJ, Galiè N, Olschewski H, Torres F, Frost A, Ghofrani HA, et al. Long-term ambrisentan therapy for the treatment of pulmonary arterial hypertension. Journal of the American College of Cardiology 2009;54(21):1971-81. x-wiley/crsRef/3192706
-
(2009)
Journal of the American College of Cardiology
, vol.54
, Issue.21
, pp. 1971-1981
-
-
Oudiz, R.J.1
Galiè, N.2
Olschewski, H.3
Torres, F.4
Frost, A.5
Ghofrani, H.A.6
-
95
-
-
85081076155
-
A randomized open label study comparing bosentan to sildenafil first-line treatment in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension [Abstract]
-
x-wiley/crsRef/16156781
-
Palazzini M, Mazzanti G, Gotti E, Bulatovic I, Manes A, Marinelli A, et al. A randomized open label study comparing bosentan to sildenafil first-line treatment in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension [Abstract]. American Journal of Respiratory and Critical Care Medicine 2010;181(Meeting Abstracts):A3357. x-wiley/crsRef/16156781
-
(2010)
American Journal of Respiratory and Critical Care Medicine
, vol.181
, Issue.Meeting Abstracts
, pp. A3357
-
-
Palazzini, M.1
Mazzanti, G.2
Gotti, E.3
Bulatovic, I.4
Manes, A.5
Marinelli, A.6
-
96
-
-
84877297353
-
Treatment of idiopathic pulmonary fibrosis with ambrisentan: a parallel, randomized trial
-
x-wiley/crsRef/16156783
-
Raghu G, Behr J, Brown KK, Egan JJ, Kawut SM, Flaherty KR, et al. Treatment of idiopathic pulmonary fibrosis with ambrisentan: a parallel, randomized trial. Annals of Internal Medicine 2013;158(9):641-9. x-wiley/crsRef/16156783
-
(2013)
Annals of Internal Medicine
, vol.158
, Issue.9
, pp. 641-649
-
-
Raghu, G.1
Behr, J.2
Brown, K.K.3
Egan, J.J.4
Kawut, S.M.5
Flaherty, K.R.6
-
97
-
-
84946594045
-
Pulmonary hypertension in idiopathic pulmonary fibrosis with mild-to-moderate restriction
-
x-wiley/crsRef/16156785
-
Raghu G, Nathan SD, Behr J, Brown KK, Egan JJ, Kawut SM, et al. Pulmonary hypertension in idiopathic pulmonary fibrosis with mild-to-moderate restriction. European Respiratory Journal 2015;46(5):1370-7. x-wiley/crsRef/16156785
-
(2015)
European Respiratory Journal
, vol.46
, Issue.5
, pp. 1370-1377
-
-
Raghu, G.1
Nathan, S.D.2
Behr, J.3
Brown, K.K.4
Egan, J.J.5
Kawut, S.M.6
-
98
-
-
73149089715
-
Bosentan as a bridge to pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension
-
x-wiley/crsRef/16156787
-
Reesink HJ, Surie S, Kloek JJ, Tan HL, Tepaske R, Fedullo PF, et al. Bosentan as a bridge to pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension. Journal of Thoracic and Cardiovascular Surgery 2010;139(1):85-91. x-wiley/crsRef/16156787
-
(2010)
Journal of Thoracic and Cardiovascular Surgery
, vol.139
, Issue.1
, pp. 85-91
-
-
Reesink, H.J.1
Surie, S.2
Kloek, J.J.3
Tan, H.L.4
Tepaske, R.5
Fedullo, P.F.6
-
99
-
-
33644856615
-
A study of aspirin and clopidogrel in idiopathic pulmonary arterial hypertension
-
x-wiley/crsRef/3192712
-
Robbins IM, Kawut SM, Yung D, Reilly MP, Lloyd W, Cunningham G, et al. A study of aspirin and clopidogrel in idiopathic pulmonary arterial hypertension. European Respiratory Journal 2006;27(3):578-84. x-wiley/crsRef/3192712
-
(2006)
European Respiratory Journal
, vol.27
, Issue.3
, pp. 578-584
-
-
Robbins, I.M.1
Kawut, S.M.2
Yung, D.3
Reilly, M.P.4
Lloyd, W.5
Cunningham, G.6
-
100
-
-
0031863914
-
Systemic and renal effects of an ET(A) receptor subtype-specific antagonist in healthy subjects
-
Eichler H-G,, x-wiley/crsRef/16156789
-
Schmetterer L, Dallinger S, Bobr B, Selenko N, Eichler H-G, Wolzt M. Systemic and renal effects of an ET(A) receptor subtype-specific antagonist in healthy subjects. British Journal of Pharmacology 1998;124(5):930-4. x-wiley/crsRef/16156789
-
(1998)
British Journal of Pharmacology
, vol.124
, Issue.5
, pp. 930-934
-
-
Schmetterer, L.1
Dallinger, S.2
Bobr, B.3
Selenko, N.4
Wolzt, M.5
-
102
-
-
84878017417
-
Impact of bosentan on exercise capacity in adults after the Fontan procedure: a randomized controlled trial
-
x-wiley/crsRef/16156793
-
Schuuring MJ, Vis JC, van Dijk AP, van Melle JP, Vliegen HW, Pieper PG, et al. Impact of bosentan on exercise capacity in adults after the Fontan procedure: a randomized controlled trial. European Journal of Heart Failure 2013;15(6):690-8. x-wiley/crsRef/16156793
-
(2013)
European Journal of Heart Failure
, vol.15
, Issue.6
, pp. 690-698
-
-
Schuuring, M.J.1
Vis, J.C.2
van Dijk, A.P.3
van Melle, J.P.4
Vliegen, H.W.5
Pieper, P.G.6
-
103
-
-
60449099543
-
Prophylactic bosentan does not improve exercise capacity or lower pulmonary artery systolic pressure at high altitude
-
x-wiley/crsRef/16156795
-
Seheult RD, Ruh K, Foster GP, Anholm JD. Prophylactic bosentan does not improve exercise capacity or lower pulmonary artery systolic pressure at high altitude. Respiratory Physiology and Neurobiology 2009;165(2-3):123-30. x-wiley/crsRef/16156795
-
(2009)
Respiratory Physiology and Neurobiology
, vol.165
, Issue.2-3
, pp. 123-130
-
-
Seheult, R.D.1
Ruh, K.2
Foster, G.P.3
Anholm, J.D.4
-
104
-
-
77954222367
-
Randomized, prospective, placebo-controlled trial of bosentan in interstitial lung disease secondary to systemic sclerosis
-
x-wiley/crsRef/16156797
-
Seibold JR, Denton CP, Furst DE, Guillevin L, Rubin LJ, Wells A, et al. Randomized, prospective, placebo-controlled trial of bosentan in interstitial lung disease secondary to systemic sclerosis. Arthritis and Rheumatism 2010;62(7):2101-8. x-wiley/crsRef/16156797
-
(2010)
Arthritis and Rheumatism
, vol.62
, Issue.7
, pp. 2101-2108
-
-
Seibold, J.R.1
Denton, C.P.2
Furst, D.E.3
Guillevin, L.4
Rubin, L.J.5
Wells, A.6
-
105
-
-
34447544360
-
Improvement of vascular endothelial function using the oral endothelin receptor antagonist bosentan in patients with systemic sclerosis
-
x-wiley/crsRef/16156799
-
Sfikakis PP, Papamichael C, Stamatelopoulos KS, Tousoulis D, Fragiadaki KG, Katsichti P, et al. Improvement of vascular endothelial function using the oral endothelin receptor antagonist bosentan in patients with systemic sclerosis. Arthritis and Rheumatism 2007;56(6):1985-93. x-wiley/crsRef/16156799
-
(2007)
Arthritis and Rheumatism
, vol.56
, Issue.6
, pp. 1985-1993
-
-
Sfikakis, P.P.1
Papamichael, C.2
Stamatelopoulos, K.S.3
Tousoulis, D.4
Fragiadaki, K.G.5
Katsichti, P.6
-
106
-
-
84891850009
-
Efficacy of endothelin receptor antagonist bosentan on the long-term prognosis in patients after Fontan operation
-
x-wiley/crsRef/16156801
-
Shang XK, Li YP, Liu M, Zhou HM, Peng T, Deng XX, et al. Efficacy of endothelin receptor antagonist bosentan on the long-term prognosis in patients after Fontan operation. Zhonghua Xin Xue Guan Bing Za Zhi 2013;41(12):1025-8. x-wiley/crsRef/16156801
-
(2013)
Zhonghua Xin Xue Guan Bing Za Zhi
, vol.41
, Issue.12
, pp. 1025-1028
-
-
Shang, X.K.1
Li, Y.P.2
Liu, M.3
Zhou, H.M.4
Peng, T.5
Deng, X.X.6
-
107
-
-
84979784650
-
Efficacy of bosentan in patients after fontan procedures: a double-blind, randomized controlled trial
-
x-wiley/crsRef/16156803
-
Shang XK, Lu R, Zhang X, Zhang CD, Xiao SN, Liu M, et al. Efficacy of bosentan in patients after fontan procedures: a double-blind, randomized controlled trial. Journal of Huazhong University of Science and Technology [Medical Sciences] 2016;36(4):534-40. x-wiley/crsRef/16156803
-
(2016)
Journal of Huazhong University of Science and Technology [Medical Sciences]
, vol.36
, Issue.4
, pp. 534-540
-
-
Shang, X.K.1
Lu, R.2
Zhang, X.3
Zhang, C.D.4
Xiao, S.N.5
Liu, M.6
-
108
-
-
85064589682
-
Comparison of efficacy of different treatment regimens in pulmonary hypertension secondary to lung disease and/or hypoxia [Abstract]
-
x-wiley/crsRef/16156805
-
Sharma SK, Ajmani S, Sharma A, Singh S, Sinha S, Vishnubhatla S, et al. Comparison of efficacy of different treatment regimens in pulmonary hypertension secondary to lung disease and/or hypoxia [Abstract]. American Journal of Respiratory and Critical Care Medicine 2014;189:A1892. x-wiley/crsRef/16156805
-
(2014)
American Journal of Respiratory and Critical Care Medicine
, vol.189
, pp. A1892
-
-
Sharma, S.K.1
Ajmani, S.2
Sharma, A.3
Singh, S.4
Sinha, S.5
Vishnubhatla, S.6
-
110
-
-
84857627601
-
Investigation of the effect of ketoconazole on the pharmacokinetics of macitentan in healthy male subjects
-
x-wiley/crsRef/16156807
-
Sidharta PN, Atsmon J, Dingemanse J. Investigation of the effect of ketoconazole on the pharmacokinetics of macitentan in healthy male subjects. British Journal of Clinical Pharmacology 2010;70(6):930-1. x-wiley/crsRef/16156807
-
(2010)
British Journal of Clinical Pharmacology
, vol.70
, Issue.6
, pp. 930-931
-
-
Sidharta, P.N.1
Atsmon, J.2
Dingemanse, J.3
-
111
-
-
84892915544
-
Safety, tolerability, pharmacokinetics, and pharmacodynamics of macitentan, an endothelin receptor antagonist, in an ascending multiple-dose study in healthy subjects
-
x-wiley/crsRef/16704627
-
Sidharta PN, van Giersbergen PL, Dingemanse J. Safety, tolerability, pharmacokinetics, and pharmacodynamics of macitentan, an endothelin receptor antagonist, in an ascending multiple-dose study in healthy subjects. Journal of Clinical Pharmacology 2013;53(11):1131-8. x-wiley/crsRef/16704627
-
(2013)
Journal of Clinical Pharmacology
, vol.53
, Issue.11
, pp. 1131-1138
-
-
Sidharta, P.N.1
van Giersbergen, P.L.2
Dingemanse, J.3
-
112
-
-
84893153286
-
Macitentan, a novel dual endothelin receptor antagonist, does not prolong the QT/QTC interval in a thorough QTC study in healthy subjects
-
x-wiley/crsRef/16704629
-
Sidharta PN, Lindegger N, Reseski K, Dingemanse J. Macitentan, a novel dual endothelin receptor antagonist, does not prolong the QT/QTC interval in a thorough QTC study in healthy subjects. Clinical Pharmacology and Therapeutics 2013;93(Suppl 1):S108-9. x-wiley/crsRef/16704629
-
(2013)
Clinical Pharmacology and Therapeutics
, vol.93
, pp. S108-S109
-
-
Sidharta, P.N.1
Lindegger, N.2
Reseski, K.3
Dingemanse, J.4
-
113
-
-
84904557356
-
Investigation of the effect of macitentan on the pharmacokinetics and pharmacodynamics of warfarin in healthy male subjects
-
x-wiley/crsRef/16156813
-
Sidharta PN, Dietrich H, Dingemanse J. Investigation of the effect of macitentan on the pharmacokinetics and pharmacodynamics of warfarin in healthy male subjects. Clinical Drug Investigation 2014;34(8):545-52. x-wiley/crsRef/16156813
-
(2014)
Clinical Drug Investigation
, vol.34
, Issue.8
, pp. 545-552
-
-
Sidharta, P.N.1
Dietrich, H.2
Dingemanse, J.3
-
114
-
-
79551663361
-
Efficacy, safety and tolerability of ACT-293987, a novel oral, non-prostanoid, prostaglandin I2 (IP) receptor agonist: results from a phase IIa study in pulmonary arterial hypertension (PAH)
-
x-wiley/crsRef/3192720
-
Simonneau G, Lang I, Torbicki A, Hoeper MM, Delcroix M, Karlocai K, et al. Efficacy, safety and tolerability of ACT-293987, a novel oral, non-prostanoid, prostaglandin I2 (IP) receptor agonist: results from a phase IIa study in pulmonary arterial hypertension (PAH). American Journal of Respiratory and Critical Care Medicine 2010;181(Meeting Abstracts):A2515. x-wiley/crsRef/3192720
-
(2010)
American Journal of Respiratory and Critical Care Medicine
, vol.181
, Issue.Meeting Abstracts
, pp. A2515
-
-
Simonneau, G.1
Lang, I.2
Torbicki, A.3
Hoeper, M.M.4
Delcroix, M.5
Karlocai, K.6
-
115
-
-
85103091313
-
Macitentan for inoperable chronic thromboembolic pulmonary hypertension (CTEPH): results from the randomised controlled MERIT study
-
x-wiley/crsRef/16156815
-
Simonneau G, Jing ZC, D'Armini AM, Fedullo P, Howard L, Jais X, et al. Macitentan for inoperable chronic thromboembolic pulmonary hypertension (CTEPH): results from the randomised controlled MERIT study. European Respiratory Journal 2017;50(Suppl 61):OA1984. x-wiley/crsRef/16156815
-
(2017)
European Respiratory Journal
, vol.50
, pp. OA1984
-
-
Simonneau, G.1
Jing, Z.C.2
D'Armini, A.M.3
Fedullo, P.4
Howard, L.5
Jais, X.6
-
116
-
-
57449121379
-
Pharmacokinetics and safety of ambrisentan in combination with sildenafil in healthy volunteers
-
x-wiley/crsRef/3192722
-
Spence R, Mandagere A, Dufton C, Venitz J. Pharmacokinetics and safety of ambrisentan in combination with sildenafil in healthy volunteers. Journal of Clinical Pharmacology 2008;48(12):1451-9. x-wiley/crsRef/3192722
-
(2008)
Journal of Clinical Pharmacology
, vol.48
, Issue.12
, pp. 1451-1459
-
-
Spence, R.1
Mandagere, A.2
Dufton, C.3
Venitz, J.4
-
117
-
-
70849086064
-
No clinically relevant pharmacokinetic and safety interactions of ambrisentan in combination with tadalafil in healthy volunteers
-
x-wiley/crsRef/3192724
-
Spence R, Mandagere A, Harrison B, Dufton C, Boinpally R. No clinically relevant pharmacokinetic and safety interactions of ambrisentan in combination with tadalafil in healthy volunteers. Journal of Pharmaceutical Sciences 2009;98(12):4962-74. x-wiley/crsRef/3192724
-
(2009)
Journal of Pharmaceutical Sciences
, vol.98
, Issue.12
, pp. 4962-4974
-
-
Spence, R.1
Mandagere, A.2
Harrison, B.3
Dufton, C.4
Boinpally, R.5
-
118
-
-
72949114651
-
The effects of sitaxentan on sildenafil pharmacokinetics and pharmacodynamics in healthy subjects
-
x-wiley/crsRef/3192726
-
Stavros F, Kramer WG, Wilkins MR. The effects of sitaxentan on sildenafil pharmacokinetics and pharmacodynamics in healthy subjects. British Journal of Clinical Pharmacology 2010;69(1):23-6. x-wiley/crsRef/3192726
-
(2010)
British Journal of Clinical Pharmacology
, vol.69
, Issue.1
, pp. 23-26
-
-
Stavros, F.1
Kramer, W.G.2
Wilkins, M.R.3
-
119
-
-
58149393089
-
A randomised, controlled trial of bosentan in severe COPD
-
x-wiley/crsRef/3192728
-
Stolz D, Rasch H, Linka A, Di Valentino M, Meyer A, Brutsche M, et al. A randomised, controlled trial of bosentan in severe COPD. European Respiratory Journal 2008;32(3):619-28. x-wiley/crsRef/3192728
-
(2008)
European Respiratory Journal
, vol.32
, Issue.3
, pp. 619-628
-
-
Stolz, D.1
Rasch, H.2
Linka, A.3
Di Valentino, M.4
Meyer, A.5
Brutsche, M.6
-
120
-
-
84888011241
-
Bosentan treatment is associated with improvement of right ventricular function and remodeling in chronic thromboembolic pulmonary hypertension
-
x-wiley/crsRef/16156817
-
Surie S, Reesink HJ, Marcus JT, van der Plas MN, Kloek JJ, Vonk-Noordegraaf A, et al. Bosentan treatment is associated with improvement of right ventricular function and remodeling in chronic thromboembolic pulmonary hypertension. Clinical Cardiology 2013;36(11):698-703. x-wiley/crsRef/16156817
-
(2013)
Clinical Cardiology
, vol.36
, Issue.11
, pp. 698-703
-
-
Surie, S.1
Reesink, H.J.2
Marcus, J.T.3
van der Plas, M.N.4
Kloek, J.J.5
Vonk-Noordegraaf, A.6
-
121
-
-
85038110456
-
Potential benefit of bosentan therapy in borderline or less severe pulmonary hypertension secondary to idiopathic pulmonary fibrosis - an interim analysis of results from a prospective, single-center, randomized, parallel-group study
-
x-wiley/crsRef/16156819
-
Tanaka Y, Hino M, Gemma A. Potential benefit of bosentan therapy in borderline or less severe pulmonary hypertension secondary to idiopathic pulmonary fibrosis - an interim analysis of results from a prospective, single-center, randomized, parallel-group study. BMC Pulmonary Medicine 2017;17(1):200. x-wiley/crsRef/16156819 [DOI: 10.1186/s12890-017-0523-2]
-
(2017)
BMC Pulmonary Medicine
, vol.17
, Issue.1
, pp. 200
-
-
Tanaka, Y.1
Hino, M.2
Gemma, A.3
-
122
-
-
85103085592
-
Interim report: long-term influence of bosentan on prognosis, activities of daily living (ADL), cardiac function and pulmonary function in patients with pulmonary hypertension secondary to COPD
-
x-wiley/crsRef/16156821
-
Tanaka Y, Hino M, Aoyama J, Kosaihira S, Okano T, Seike M, et al. Interim report: long-term influence of bosentan on prognosis, activities of daily living (ADL), cardiac function and pulmonary function in patients with pulmonary hypertension secondary to COPD. In: Respirology. Vol. 24. 2019:239. x-wiley/crsRef/16156821
-
(2019)
Respirology
, vol.24
, pp. 239
-
-
Tanaka, Y.1
Hino, M.2
Aoyama, J.3
Kosaihira, S.4
Okano, T.5
Seike, M.6
-
123
-
-
85044309221
-
Macitentan in pulmonary hypertension due to left ventricular dysfunction
-
Vachiery J-L,, x-wiley/crsRef/16156823
-
Vachiery J-L, Delcroix M, Al-Hiti H, Efficace M, Hutyra M, Lack G, et al. Macitentan in pulmonary hypertension due to left ventricular dysfunction. European Respiratory Journal 2018;51(2):1880. x-wiley/crsRef/16156823
-
(2018)
European Respiratory Journal
, vol.51
, Issue.2
, pp. 1880
-
-
Delcroix, M.1
Al-Hiti, H.2
Efficace, M.3
Hutyra, M.4
Lack, G.5
-
124
-
-
33644501867
-
Selective endothelin B receptor blockade does not influence BNP-induced natriuresis in man
-
x-wiley/crsRef/16156825
-
Van Der Zander K, Houben AJHM, Webb DJ, Udo E, Kietselaer B, Hofstra L, et al. Selective endothelin B receptor blockade does not influence BNP-induced natriuresis in man. Kidney International 2006;69(5):864-8. x-wiley/crsRef/16156825
-
(2006)
Kidney International
, vol.69
, Issue.5
, pp. 864-868
-
-
Van Der Zander, K.1
Houben, A.J.H.M.2
Webb, D.J.3
Udo, E.4
Kietselaer, B.5
Hofstra, L.6
-
125
-
-
16644388500
-
Comparative investigation of the pharmacokinetics of bosentan in Caucasian and Japanese healthy subjects
-
x-wiley/crsRef/16156827
-
Van Giersbergen PLM, Dingemanse J. Comparative investigation of the pharmacokinetics of bosentan in Caucasian and Japanese healthy subjects. American College of Clinical Pharmacology 2005;45(1):42-7. x-wiley/crsRef/16156827
-
(2005)
American College of Clinical Pharmacology
, vol.45
, Issue.1
, pp. 42-47
-
-
Van Giersbergen, P.L.M.1
Dingemanse, J.2
-
126
-
-
85027874623
-
Longitudinal assessment of the effect of atrasentan on thoracic bioimpedance in diabetic nephropathy: a randomized, double-blind, placebo-controlled trial
-
x-wiley/crsRef/16156829
-
Webb DJ, Coll B, Heerspink HJL, Andress D, Pritchett Y, Brennan JJ, et al. Longitudinal assessment of the effect of atrasentan on thoracic bioimpedance in diabetic nephropathy: a randomized, double-blind, placebo-controlled trial. Drugs in R&D 2017;17(3):441-8. x-wiley/crsRef/16156829
-
(2017)
Drugs in R&D
, vol.17
, Issue.3
, pp. 441-448
-
-
Webb, D.J.1
Coll, B.2
Heerspink, H.J.L.3
Andress, D.4
Pritchett, Y.5
Brennan, J.J.6
-
127
-
-
85048483708
-
Safety and feasibility of inhaled iloprost on exercise capacity in patients with pulmonary arterial hypertension
-
x-wiley/crsRef/3192730
-
Worthington A, Collins N, Haddad R. Safety and feasibility of inhaled iloprost on exercise capacity in patients with pulmonary arterial hypertension. Heart Lung and Circulation 2010;19(2):1. x-wiley/crsRef/3192730
-
(2010)
Heart Lung and Circulation
, vol.19
, Issue.2
, pp. 1
-
-
Worthington, A.1
Collins, N.2
Haddad, R.3
-
128
-
-
41849103027
-
Pharmacokinetic interaction between tadalafil and bosentan in healthy male subjects
-
x-wiley/crsRef/3192732
-
Wrishko RE, Dingemanse J, Yu A, Darstein C, Phillips DL, Mitchell MI. Pharmacokinetic interaction between tadalafil and bosentan in healthy male subjects. Journal of Clinical Pharmacology 2008;48(5):610-8. x-wiley/crsRef/3192732
-
(2008)
Journal of Clinical Pharmacology
, vol.48
, Issue.5
, pp. 610-618
-
-
Wrishko, R.E.1
Dingemanse, J.2
Yu, A.3
Darstein, C.4
Phillips, D.L.5
Mitchell, M.I.6
-
129
-
-
85066078563
-
AB0797 A randomised double blind placebo controlled trial to compare the efficacy of initial combination therapy vs monotherapy for pulmonary arterial hypertension in systemic sclerosis
-
x-wiley/crsRef/16156831
-
Dwivedi P, Sharma SK, Dhir V, Rohit MK, Behera D, Jain S. AB0797 A randomised double blind placebo controlled trial to compare the efficacy of initial combination therapy vs monotherapy for pulmonary arterial hypertension in systemic sclerosis. Annals of the Rheumatic Diseases 2018;77(Suppl 2):1531. x-wiley/crsRef/16156831
-
(2018)
Annals of the Rheumatic Diseases
, vol.77
, pp. 1531
-
-
Dwivedi, P.1
Sharma, S.K.2
Dhir, V.3
Rohit, M.K.4
Behera, D.5
Jain, S.6
-
130
-
-
85100637405
-
Haemodynamic and exercise effects of different types of initial oral combination therapy in pulmonary arterial hypertension
-
x-wiley/crsRef/16156833
-
Rinaldi A, Dardi F, Albini A, Gotti E, Monti E, Palazzini M, et al. Haemodynamic and exercise effects of different types of initial oral combination therapy in pulmonary arterial hypertension. In: European Heart Journal. Vol. 39. 2018:P6341. x-wiley/crsRef/16156833
-
(2018)
European Heart Journal
, vol.39
, pp. P6341
-
-
Rinaldi, A.1
Dardi, F.2
Albini, A.3
Gotti, E.4
Monti, E.5
Palazzini, M.6
-
131
-
-
0037464808
-
Statistics notes: interaction revisited: the difference between two estimates
-
Altman DG, Bland JM. Statistics notes: interaction revisited: the difference between two estimates. BMJ 2003;326(7382):219.
-
(2003)
BMJ
, vol.326
, Issue.7382
, pp. 219
-
-
Altman, D.G.1
Bland, J.M.2
-
132
-
-
44349164345
-
Ambrisentan therapy for pulmonary arterial hypertension: a comparison by PAH etiology
-
Badesch DB, the Aries Study Group. Ambrisentan therapy for pulmonary arterial hypertension: a comparison by PAH etiology. Chest 2007;132(4):488-9.
-
(2007)
Chest
, vol.132
, Issue.4
, pp. 488-489
-
-
Badesch, D.B.1
-
133
-
-
0030031888
-
A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. The Primary Pulmonary Hypertension Study Group
-
Barst RJ, Rubin LJ, Long WA, McGoon MD, Rich S, Badesch DB. A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. The Primary Pulmonary Hypertension Study Group. New England Journal of Medicine 1996;334(5):296-302.
-
(1996)
New England Journal of Medicine
, vol.334
, Issue.5
, pp. 296-302
-
-
Barst, R.J.1
Rubin, L.J.2
Long, W.A.3
McGoon, M.D.4
Rich, S.5
Badesch, D.B.6
-
136
-
-
33750344748
-
Bosentan treatment for pulmonary arterial hypertension related to connective tissue disease: a subgroup analysis of the pivotal clinical trials and their open-label extensions
-
Denton CP, Humbert M, Rubin L, Black CM. Bosentan treatment for pulmonary arterial hypertension related to connective tissue disease: a subgroup analysis of the pivotal clinical trials and their open-label extensions. Annals of the Rheumatic Diseases 2006;65(10):1336-40.
-
(2006)
Annals of the Rheumatic Diseases
, vol.65
, Issue.10
, pp. 1336-1340
-
-
Denton, C.P.1
Humbert, M.2
Rubin, L.3
Black, C.M.4
-
137
-
-
85013173248
-
Comparative efficacy and acceptability of endothelin receptor antagonists for pulmonary arterial hypertension: a network meta-analysis
-
Duo-Ji MM, Long ZW. Comparative efficacy and acceptability of endothelin receptor antagonists for pulmonary arterial hypertension: a network meta-analysis. International Journal of Cardiology 2017;234:90-8.
-
(2017)
International Journal of Cardiology
, vol.234
, pp. 90-98
-
-
Duo-Ji, M.M.1
Long, Z.W.2
-
138
-
-
84943272997
-
2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension
-
Galiè N, Humbert M, Vachiery JL, Gibbs S, Lang I, Torbicki A, et al. 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. European Respiratory Journal 2015;46(4):903.
-
(2015)
European Respiratory Journal
, vol.46
, Issue.4
, pp. 903
-
-
Galiè, N.1
Humbert, M.2
Vachiery, J.L.3
Gibbs, S.4
Lang, I.5
Torbicki, A.6
-
140
-
-
84888811646
-
Pathogenesis of pulmonary arterial hypertension: lessons from cancer
-
Guignabert C, Tu L, Le HM, Ricard N, Sattler C, Seferian A, et al. Pathogenesis of pulmonary arterial hypertension: lessons from cancer. European Respiratory Review 2013;22(130):543.
-
(2013)
European Respiratory Review
, vol.22
, Issue.130
, pp. 543
-
-
Guignabert, C.1
Tu, L.2
Le, H.M.3
Ricard, N.4
Sattler, C.5
Seferian, A.6
-
141
-
-
85007533345
-
Cochrane Handbook for Systematic Reviews of Interventions Version 6.1 (updated September 2020). Cochrane, 2020
-
editor(s)
-
Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA, editor(s). Cochrane Handbook for Systematic Reviews of Interventions Version 6.1 (updated September 2020). Cochrane, 2020. Available from training.cochrane.org/handbook.
-
Available from training.cochrane.org/handbook
-
-
Higgins, J.P.1
Thomas, J.2
Chandler, J.3
Cumpston, M.4
Li, T.5
Page, M.J.6
Welch, V.A.7
-
142
-
-
84888598320
-
Endothelin receptor signaling: new insight into its regulatory mechanisms
-
Horinouchi T, Terada K, Higashi T, Miwa S. Endothelin receptor signaling: new insight into its regulatory mechanisms. Journal of Pharmacological Sciences 2013;123(2):85-101.
-
(2013)
Journal of Pharmacological Sciences
, vol.123
, Issue.2
, pp. 85-101
-
-
Horinouchi, T.1
Terada, K.2
Higashi, T.3
Miwa, S.4
-
143
-
-
84989284810
-
The minimal important difference in Borg dyspnea score in pulmonary arterial hypertension
-
Khair RM, Nwaneri C, Damico RL, Kolb T, Hassoun PM, Mathai SC. The minimal important difference in Borg dyspnea score in pulmonary arterial hypertension. Annals of the American Thoracic Society 2016;13(6):842-9.
-
(2016)
Annals of the American Thoracic Society
, vol.13
, Issue.6
, pp. 842-849
-
-
Khair, R.M.1
Nwaneri, C.2
Damico, R.L.3
Kolb, T.4
Hassoun, P.M.5
Mathai, S.C.6
-
144
-
-
85061735173
-
Therapy for pulmonary arterial hypertension in adults: update of the CHEST guideline and Expert Panel Report
-
Klinger JR, Elliott CG, Levine DJ, Bossone E, Duvall L, Fagan K, et al. Therapy for pulmonary arterial hypertension in adults: update of the CHEST guideline and Expert Panel Report. CHEST 2019;155(3):565-86.
-
(2019)
CHEST
, vol.155
, Issue.3
, pp. 565-586
-
-
Klinger, J.R.1
Elliott, C.G.2
Levine, D.J.3
Bossone, E.4
Duvall, L.5
Fagan, K.6
-
145
-
-
84946497143
-
Pathways and drugs in pulmonary arterial hypertension – focus on the role of endothelin receptor antagonists
-
Madonna R, Cocco N, De Caterina R. Pathways and drugs in pulmonary arterial hypertension – focus on the role of endothelin receptor antagonists. Cardiovascular Drugs Therapy 2015;29(5):469-79.
-
(2015)
Cardiovascular Drugs Therapy
, vol.29
, Issue.5
, pp. 469-479
-
-
Madonna, R.1
Cocco, N.2
De Caterina, R.3
-
146
-
-
84865804912
-
The minimal important difference in the 6-minute walk test for patients with pulmonary arterial hypertension
-
Mathai SC, Puhan MA, Lam D, Wise RA. The minimal important difference in the 6-minute walk test for patients with pulmonary arterial hypertension. American Journal of Respiratory and Critical Care Medicine 2012;186(5):428-33.
-
(2012)
American Journal of Respiratory and Critical Care Medicine
, vol.186
, Issue.5
, pp. 428-433
-
-
Mathai, S.C.1
Puhan, M.A.2
Lam, D.3
Wise, R.A.4
-
147
-
-
0034107636
-
Clinical correlates and prognostic significance of six-minute walk test in patients with primary pulmonary hypertension. Comparison with cardiopulmonary exercise testing
-
Miyamoto S, Nagaya N, Satoh T, Kyotani S, Sakamaki F, Fujita M, et al. Clinical correlates and prognostic significance of six-minute walk test in patients with primary pulmonary hypertension. Comparison with cardiopulmonary exercise testing. American Journal of Respiratory and Critical Care Medicine 2000;161:487-92.
-
(2000)
American Journal of Respiratory and Critical Care Medicine
, vol.161
, pp. 487-492
-
-
Miyamoto, S.1
Nagaya, N.2
Satoh, T.3
Kyotani, S.4
Sakamaki, F.5
Fujita, M.6
-
149
-
-
0026632785
-
The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension
-
Rich S, Kaufmann E, Levy PS. The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension. New England Journal of Medicine 1992;327(2):76-81.
-
(1992)
New England Journal of Medicine
, vol.327
, Issue.2
, pp. 76-81
-
-
Rich, S.1
Kaufmann, E.2
Levy, P.S.3
-
150
-
-
33745309657
-
Sitaxsentan, a selective endothelin-a receptor antagonist, improves exercise capacity in pulmonary arterial hypertension (PAH) associated with connective tissue disease (CTD)
-
Seibold J, Badesch D, Galiè N, Langleben D, Naeije R, Simonneau G, et al. Sitaxsentan, a selective endothelin-a receptor antagonist, improves exercise capacity in pulmonary arterial hypertension (PAH) associated with connective tissue disease (CTD). CHEST 2005;128(4):219S.
-
(2005)
CHEST
, vol.128
, Issue.4
, pp. 219S
-
-
Seibold, J.1
Badesch, D.2
Galiè, N.3
Langleben, D.4
Naeije, R.5
Simonneau, G.6
-
151
-
-
79958069658
-
The role of endothelin-1 in the pathogenesis of pulmonary arterial hypertension
-
Shao D, Park JE, Wort SJ. The role of endothelin-1 in the pathogenesis of pulmonary arterial hypertension. Pharmacological Research 2011;63(6):504-11.
-
(2011)
Pharmacological Research
, vol.63
, Issue.6
, pp. 504-511
-
-
Shao, D.1
Park, J.E.2
Wort, S.J.3
-
152
-
-
85060524284
-
Haemodynamic definitions and updated clinical classification of pulmonary hypertension
-
Simonneau G, Montani D, Celermajer DS, Denton CP, Gatzoulis MA, Krowka M, et al. Haemodynamic definitions and updated clinical classification of pulmonary hypertension. European Respiratory Journal 2019;53(1):1801913.
-
(2019)
European Respiratory Journal
, vol.53
, Issue.1
, pp. 1801913
-
-
Simonneau, G.1
Montani, D.2
Celermajer, D.S.3
Denton, C.P.4
Gatzoulis, M.A.5
Krowka, M.6
-
153
-
-
0031869664
-
Inhaled nitric oxide as a screening agent for safely identifying responders to oral calcium-channel blockers in primary pulmonary hypertension
-
Sitbon O, Humbert M, Jagot JL, Taravella O, Fartoukh M, Parent F, et al. Inhaled nitric oxide as a screening agent for safely identifying responders to oral calcium-channel blockers in primary pulmonary hypertension. European Respiratory Journal 1998;12:265-70.
-
(1998)
European Respiratory Journal
, vol.12
, pp. 265-270
-
-
Sitbon, O.1
Humbert, M.2
Jagot, J.L.3
Taravella, O.4
Fartoukh, M.5
Parent, F.6
-
154
-
-
0037151645
-
Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: prognostic factors and survival
-
Sitbon O, Humbert M, Nunes H, Parent F, Garcia G, Herve P, et al. Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: prognostic factors and survival. Journal of the American College of Cardiology 2002;40(4):780-8.
-
(2002)
Journal of the American College of Cardiology
, vol.40
, Issue.4
, pp. 780-788
-
-
Sitbon, O.1
Humbert, M.2
Nunes, H.3
Parent, F.4
Garcia, G.5
Herve, P.6
-
155
-
-
85044026121
-
Pulmonary arterial hypertension: pathogenesis and clinical management
-
Thenappan T, Ormiston ML, Ryan JJ, Archer SL. Pulmonary arterial hypertension: pathogenesis and clinical management. BMJ 2018;360:j5492.
-
(2018)
BMJ
, vol.360
, pp. j5492
-
-
Thenappan, T.1
Ormiston, M.L.2
Ryan, J.J.3
Archer, S.L.4
-
156
-
-
85056663570
-
A Bayesian network meta-analysis on the efficacy and safety of eighteen targeted drugs or drug combinations for pulmonary arterial hypertension
-
Wang S, Yu M, Zheng X, Dong S. A Bayesian network meta-analysis on the efficacy and safety of eighteen targeted drugs or drug combinations for pulmonary arterial hypertension. Drug Delivery 2018;25(1):1898-909.
-
(2018)
Drug Delivery
, vol.25
, Issue.1
, pp. 1898-1909
-
-
Wang, S.1
Yu, M.2
Zheng, X.3
Dong, S.4
-
157
-
-
84902012561
-
Randomized study of adding tadalafil to existing ambrisentan in pulmonary arterial hypertension
-
Zhuang Y, Jiang B, Gao H, Zhao W. Randomized study of adding tadalafil to existing ambrisentan in pulmonary arterial hypertension. Hypertension Research 2014;37(6):507-12.
-
(2014)
Hypertension Research
, vol.37
, Issue.6
, pp. 507-512
-
-
Zhuang, Y.1
Jiang, B.2
Gao, H.3
Zhao, W.4
-
158
-
-
85103079202
-
Endothelin receptor antagonists for pulmonary arterial hypertension
-
Issue, Art. CD004434
-
Liu C, Chen J. Endothelin receptor antagonists for pulmonary arterial hypertension. Cochrane Database of Systematic Reviews 2004, Issue 4. Art. No: CD004434. [DOI: 10.1002/14651858.CD004434.pub2]
-
(2004)
Cochrane Database of Systematic Reviews
, Issue.4
-
-
Liu, C.1
Chen, J.2
-
159
-
-
85103079202
-
Endothelin receptor antagonists for pulmonary arterial hypertension
-
Issue, Art. CD004434
-
Liu C, Chen J. Endothelin receptor antagonists for pulmonary arterial hypertension. Cochrane Database of Systematic Reviews 2006, Issue 3. Art. No: CD004434. [DOI: 10.1002/14651858.CD004434.pub3]
-
(2006)
Cochrane Database of Systematic Reviews
, Issue.3
-
-
Liu, C.1
Chen, J.2
-
160
-
-
85103079202
-
Endothelin receptor antagonists for pulmonary arterial hypertension
-
Issue, Art. CD004434
-
Liu C, Chen J, Gao Y, Deng B, Liu K. Endothelin receptor antagonists for pulmonary arterial hypertension. Cochrane Database of Systematic Reviews 2009, Issue 3. Art. No: CD004434. [DOI: 10.1002/14651858.CD004434.pub4]
-
(2009)
Cochrane Database of Systematic Reviews
, Issue.3
-
-
Liu, C.1
Chen, J.2
Gao, Y.3
Deng, B.4
Liu, K.5
-
161
-
-
85103079202
-
Endothelin receptor antagonists for pulmonary arterial hypertension
-
Issue, Art. CD004434
-
Liu C, Chen J, Gao Y, Deng B, Liu K. Endothelin receptor antagonists for pulmonary arterial hypertension. Cochrane Database of Systematic Reviews 2013, Issue 2. Art. No: CD004434. [DOI: 10.1002/14651858.CD004434.pub5]
-
(2013)
Cochrane Database of Systematic Reviews
, Issue.2
-
-
Liu, C.1
Chen, J.2
Gao, Y.3
Deng, B.4
Liu, K.5
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