Tezosentan and right ventricular failure in patients with pulmonary hypertension undergoing cardiac surgery: The TACTICS trial

Journal of Cardiothoracic and Vascular Anesthesia

Volumn 27, Issue 6, 2013, Pages 1212-1217

  Denault, André Y ^a   Pearl, Ronald G ^b   Michler, Robert E ^c   Rao, Vivek ^d   Tsui, Steven S L ^e   Seitelberger, Rainald ^f   Cromie, Matt ^g   Lindberg, Elisabet ^g   D'Armini, Andrea M ^h  

^a MONTREAL HEART INSTITUTE   (Canada)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^d TORONTO GENERAL HOSPITAL   (Canada)

^e PAPWORTH HOSPITAL   (United Kingdom)

^f UNIVERSITY OF VIENNA   (Austria)

^g ACTELION PHARMACEUTICALS LTD   (Switzerland)

^h UNIVERSITY OF PAVIA   (Italy)

Author keywords

cardiopulmonary bypass; endothelin receptor antagonist; left sided heart disease; pulmonary hypertension; right ventricular failure; tezosentan

Indexed keywords

ADRENALIN; DOBUTAMINE; DOPAMINE; ISOPRENALINE; LEVOSIMENDAN; MILRINONE; NITRIC OXIDE; NORADRENALIN; PHENYLEPHRINE; PLACEBO; TEZOSENTAN; VASOPRESSIN;

ACUTE KIDNEY FAILURE; ADULT; AGED; ANEMIA; ARTICLE; ARTIFICIAL VENTILATION; CARDIOPULMONARY BYPASS; CARDIOVASCULAR MORTALITY; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG MEGADOSE; FEMALE; HEART ATRIUM FIBRILLATION; HEART RIGHT VENTRICLE FAILURE; HEART SURGERY; HUMAN; HYPOTENSION; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; OUTCOME ASSESSMENT; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; RISK REDUCTION; THROMBOCYTOPENIA; TREATMENT DURATION; TREATMENT OUTCOME;

CARDIOPULMONARY BYPASS; ENDOTHELIN RECEPTOR ANTAGONIST; LEFT-SIDED HEART DISEASE; PULMONARY HYPERTENSION; RIGHT VENTRICULAR FAILURE; TEZOSENTAN;

ADULT; AGED; AGED, 80 AND OVER; CARDIAC SURGICAL PROCEDURES; CARDIOPULMONARY BYPASS; DOUBLE-BLIND METHOD; ENDPOINT DETERMINATION; FEMALE; HEART FAILURE; HUMANS; HYPERTENSION, PULMONARY; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED; PYRIDINES; TETRAZOLES; VASODILATOR AGENTS; VENTRICULAR DYSFUNCTION, RIGHT; YOUNG ADULT;

EID: 84888289239     PISSN: 10530770     EISSN: 15328422     Source Type: Journal    
DOI: 10.1053/j.jvca.2013.01.023     Document Type: Article

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