Effects of the oral endothelin-receptor antagonist bosentan on echocardiographic and Doppler measures in patients with pulmonary arterial hypertension

Journal of the American College of Cardiology

Volumn 41, Issue 8, 2003, Pages 1380-1386

  Galiè, Nazzareno ^a   Hinderliter, Alan L ^b   Torbicki, Adam ^c   Fourme, Thierry ^d   Simonneau, Gerald ^d   Pulido, Tomas ^e   Espinola Zavaleta, Nilda ^e   Rocchi, Guido ^a   Manes, Alessandra ^a   Frantz, Robert ^f   Kurzyna, Marcin ^c   Nagueh, Sherif F ^g   Barst, Robyn ^h   Channick, Richard ⁱ   Dujardin, Karl ^j   Kronenberg, Andrew ^b   Leconte, Isabelle ^k   Rainisio, Maurizio ^k   Rubin, Lewis ⁱ  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c Instytute of Tuberculosis and Lung Diseases   (Poland)

^d UNIVERSITÉ PARIS SACLAY   (France)

^e INSTITUTO NACIONAL DE CARDIOLOGÍA IGNACIO CHÁVEZ   (Mexico)

^f MAYO CLINIC   (United States)

^g HOUSTON METHODIST HOSPITAL   (United States)

^h Columbia Univ Coll of Phys/Surgs ^*  (United States)

ⁱ UNIVERSITY OF CALIFORNIA   (United States)

^j UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^k ACTELION PHARMACEUTICALS LTD   (Switzerland)

more..

Author keywords

[No Author keywords available]

Indexed keywords

BOSENTAN; ENDOTHELIN RECEPTOR ANTAGONIST; PLACEBO;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DOPPLER FLOWMETRY; DRUG EFFECT; ECHOCARDIOGRAPHY; FEMALE; HEART INDEX; HEART LEFT VENTRICLE; HEART RIGHT VENTRICLE; HEART VENTRICLE FUNCTION; HEART VENTRICLE SIZE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PERICARDIAL EFFUSION; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RANDOMIZED CONTROLLED TRIAL; SYSTOLIC BLOOD PRESSURE; TREATMENT OUTCOME; WALKING;

EID: 0344837813     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0735-1097(03)00121-9     Document Type: Article

References (28)

1. Nomenclature Committee. Nomenclature and Classification of Pulmonary Hypertension. Rich S. Primary pulmonary hypertension: executive summary from the World Symposium-Primary Pulmonary Hypertension 1998, 25-27. World Health Organization. Available at: http://www.who.int/ncd/cvd/pph.html.
2. Rubin LJ. Primary pulmonary hypertension. N Engl J Med 1997;336: 111-7.
3. MacGregor AJ, Canavan R, Knight C, et al. Pulmonary hypertension in systemic sclerosis: risk factors for progression and consequences for survival. Rheumatology (Oxford) 2001;40:453-9.
4. Channick RN, Simonneau G, Sitbon O, et al. Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study. Lancet 2001;358:1119-23.
5. Rubin LJ, Badesch DB, Barst RJ, et al. Bosentan therapy for pulmonary arterial hypertension. N Engl J Med 2002;346:896-903.
6. Guyatt GH, Sullivan MJ, Thompson PJ, et al. The 6-minute walk: a new measure of exercise capacity in patients with chronic failure. Can Med Assoc J 1985;132:919-23.
7. Miyamoto S, Nagaya N, Satoh T, et al. Clinical correlates and prognostic significance of six-minute walk test in patients with primary pulmonary hypertension. Comparison with cardiopulmonary exercise testing. Am J Respir Crit Care Med 2000;161:487-92.
8. Naeije R, Torbicki A. More on the noninvasive diagnosis of pulmonary hypertension: Doppler echocardography revisited. Eur Respir J 1995;8:1449.
9. Bossone E, Duong Wagner TH, Paciocco G, et al. Echocardiographic features of primary pulmonary hypertension. J Am Soc Echocardiogr 1999;12:655-62.
10. Hinderliter AL, Willis PW, Barst RJ, et al. Effects of long-term infusion of prostacyclin (epoprostenol) on echocardiographic measures of right ventricular structure and function in primary pulmonary hypertension. Primary Pulmonary Hypertension Study Group. Circulation 1997;95:1479-86.
11. Ritchie M, Waggoner AD, Dávila RV, Barzilai B, Trulock EP, Eisenberg PR. Echocardiographic characterization of the improvement in right ventricular function in patients with severe pulmonary hypertension after single-lung transplantation. J Am Coll Cardiol 1993;22:1170-4.
12. Xie GY, Lin CS, Preston HM, et al. Assessment of left ventricular diastolic function after single lung transplantation in patients with severe pulmonary hypertension. Chest 1998;114:477-81.
13. Menzel T, Wagner S, Kramm T, et al. Pathophysiology of impaired right and left ventricular function in chronic embolic pulmonary hypertension: changes after pulmonary thromboendarterectomy. Chest 2000;118:897-903.
14. Menzel T, Kramm T, Bruckner A, Mohr-Kahaly S, Mayer E, Meyer J. Quantitative assessment of right ventricular volumes in severe chronic thromboembolic pulmonary hypertension using transthoracic three-dimensional echocardiography: changes due to pulmonary thromboendarterectomy. Eur J Echocardiogr 2002;3:67-72.
15. Menzel T, Kramm T, Mohr-Kahaly S, Mayer E, Oelert H, Meyer J. Assessment of cardiac performance using Tei indices in patients undergoing pulmonary thromboendarterectomy. Ann Thorac Surg 2002;73:762-6.
16. Menzel T, Kramm T, Wagner S, Mohr-Kahaly S, Mayer E, Meyer J. Improvement of tricuspid regurgitation after pulmonary thromboendarterectomy. Ann Thorac Surg 2002;73:756-61.
17. Kaul S, Tei C, Hopkins J, Shaw P. Assessment of right ventricular function using two-dimensional echocardiography. Am Heart J 1984;107:526-31.
18. Ritchie M, Waggoner AD, Dávila RV, Barzilai B, Trulock EP, Eisenberg PR. Echocardiographic characterization of the improvement in right ventricular function in patients with severe pulmonary hypertension after single-lung transplantation. J Am Coll Cardiol 1993;22:1170-4.
19. Ryan T, Petrovic O, Dillon JC, Feigenbaum HF, Conley MJ, Armstrong W. An echocardiographic index for separation of right ventricular volume and pressure overload. J Am Coll Cardiol 1985;5: 918-24.
20. Yeo TC, Dujardin KS, Tei C, Mahoney DW, McGoon MD, Seward JB. Value of a Doppler-derived index combining systolic and diastolic time intervals in predicting outcome in primary pulmonary hypertension. Am J Cardiol 1998;81:1157-61.
21. Marshall SA, Weyman AE. Doppler estimation of volumetric flow. In: Weyman AE, editor. Principle and Practice of Echocardiography. Philadelphia, PA: Lea and Febiger, 1994:978-95.
22. Raymond RJ, Hinderliter AL, Willis PW, et al. Echocardiographic predictors of adverse outcomes in primary pulmonary hypertension. J Am Coll Cardiol 2002;39:1214-9.
23. Tei C, Dujardin KS, Hodge DO, et al. Doppler echocardiographic index for assessment of global right ventricular function. J Am Soc Echocardiogr 1996;9:838-47.
24. Bossone E, Rubenfire M, Bach DS, Ricciardi M, Armstrong WF. Range of tricuspid regurgitation velocity at rest and during exercise in normal adult men: implications for the diagnosis of pulmonary hypertension. J Am Coll Cardiol 1999;33:1662-6.
25. Bossone E, Avelar E, Bach DS, Gillespie B, Rubenfire M, Armstrong WF. Diagnostic value of resting tricuspid regurgitation velocity and right ventricular ejection flow parameters for the detection of exercise induced pulmonary arterial hypertension. Int J Card Imaging 2000;16:429-36.
26. Hinderliter AL, Willis PW, Long W, et al. Frequency and prognostic significance of pericardial effusion in primary pulmonary hypertension. PPH Study Group. Primary pulmonary hypertension. Am J Cardiol 1999;84:481-4.
27. Menzel T, Wagner S, Kramm T, et al. Pathophysiology of impaired right and left ventricular function in chronic embolic pulmonary hypertension: changes after pulmonary thromboendarterectomy. Chest 2000;118:897-903.
28. Mahmud E, Raisinghani A, Hassankhani A, et al. Correlation of left ventricular diastolic filling characteristics with right ventricular overload and pulmonary artery pressure in chronic thromboembolic pulmonary hypertension. J Am Coll Cardiol 2002;40:318-24.