Inhibitory effects of glycopyrronium, formoterol, and budesonide on coronavirus HCoV-229E replication and cytokine production by primary cultures of human nasal and tracheal epithelial cells

Respiratory Investigation

Volumn 58, Issue 3, 2020, Pages 155-168

  Yamaya, Mutsuo ^a   Nishimura, Hidekazu ^b   Deng, Xue ^a   Sugawara, Mitsuru ^c   Watanabe, Oshi ^b   Nomura, Kazuhiro ^d   Shimotai, Yoshitaka ^e   Momma, Haruki ^d   Ichinose, Masakazu ^d   Kawase, Tetsuaki ^f  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SENDAI CITY MEDICAL CENTER   (Japan)

^c TOHOKU ROSAI HOSPITAL   (Japan)

^d TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e YAMAGATA UNIVERSITY   (Japan)

^f TOHOKU UNIVERSITY   (Japan)

Author keywords

Airway epithelial cells; CD13; HCoV 229E; Long acting muscarinic antagonist; Long acting 2 agonist

Indexed keywords

2'2' DIPYRIDYL; BETA INTERFERON; BUDESONIDE; CYCLIC AMP; FORMOTEROL; GLYCOPYRRONIUM; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; LONG ACTING DRUG; MICROSOMAL AMINOPEPTIDASE; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; VIRUS RNA; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CYTOKINE; FORMOTEROL FUMARATE; MUSCARINIC RECEPTOR BLOCKING AGENT;

ADULT; AGED; ANTIGEN EXPRESSION; ANTIVIRAL ACTIVITY; ARTICLE; CELL CULTURE; CLINICAL ARTICLE; CONTROLLED STUDY; CORONAVIRUS INFECTION; CYTOKINE PRODUCTION; CYTOPLASM; EPITHELIUM CELL; FEMALE; FLUORESCENCE; HUMAN; HUMAN CELL; HUMAN CORONAVIRUS 229E; INFECTION SENSITIVITY; MALE; MIDDLE AGED; NONHUMAN; PROTEIN EXPRESSION; VIRUS LOAD; VIRUS REPLICATION; CORONAVIRINAE; CYTOLOGY; DRUG EFFECT; METABOLISM; NOSE MUCOSA; PHYSIOLOGY; TRACHEA; VIROLOGY;

ADRENERGIC BETA-2 RECEPTOR AGONISTS; BUDESONIDE; CD13 ANTIGENS; CELLS, CULTURED; CORONAVIRUS; CYTOKINES; EPITHELIAL CELLS; FORMOTEROL FUMARATE; GLYCOPYRROLATE; HUMANS; MUSCARINIC ANTAGONISTS; NASAL MUCOSA; TRACHEA; VIRUS REPLICATION;

EID: 85083506930     PISSN: 22125345     EISSN: 22125353     Source Type: Journal    
DOI: 10.1016/j.resinv.2019.12.005     Document Type: Article

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