Characteristics of flavonoids as potent MERS-CoV 3C-like protease inhibitors

Chemical Biology and Drug Design

Volumn 94, Issue 6, 2019, Pages 2023-2030

  Jo, Seri ^a   Kim, Hyojin ^a   Kim, Suwon ^a   Shin, Dong Hae ^a   Kim, Mi Sun ^a  

^a Ewha Womans University   (South Korea)

Author keywords

flavonoid; FRET; inhibitory compounds; MERS CoV; MERS CoV 3CLpro

Indexed keywords

FLAVONOID; HELICHRYSETIN; HERBACETIN; ISOBAVACHALCONE; ISOQUERCITRIN; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS 3C LIKE PROTEASE; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG; VIRUS ENZYME; ANTIVIRUS AGENT; GLUCOSIDE; PEPTIDE HYDROLASE; PROTEIN BINDING; QUERCETIN; QUERCETIN 3'-O-GLUCOSIDE; RECOMBINANT PROTEIN; VIRAL PROTEIN;

ANTIVIRAL ACTIVITY; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; DRUG BINDING SITE; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; FLUORESCENCE; HYDROPHOBICITY; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; MOLECULAR DOCKING; MOLECULAR LIBRARY; NONHUMAN; PRIORITY JOURNAL; BINDING SITE; BIOSYNTHESIS; CHEMISTRY; ENZYMOLOGY; GENETICS; HUMAN; ISOLATION AND PURIFICATION; METABOLISM;

ANTIVIRAL AGENTS; BINDING SITES; FLAVONOIDS; GLUCOSIDES; HUMANS; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; MOLECULAR DOCKING SIMULATION; PEPTIDE HYDROLASES; PROTEASE INHIBITORS; PROTEIN BINDING; QUERCETIN; RECOMBINANT PROTEINS; VIRAL PROTEINS;

EID: 85073793068     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/cbdd.13604     Document Type: Article

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