NLRP3 inflammasome activation in platelets in response to sepsis

Physiological Reports

Volumn 7, Issue 9, 2019, Pages

  Cornelius, Denise C ^a,b   Baik, Cedar H ^a   Travis, Olivia K ^a   White, Dakota L ^a   Young, Cassandra M ^a   Austin Pierce, W ^a   Shields, Corbin A ^a   Poudel, Bibek ^a   Williams, Jan M ^a,b  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

Endothelial permeability; inflammation; multiorgan injury; NLRP3; platelets; sepsis

Indexed keywords

CRYOPYRIN; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; NEUTROPHIL CYTOPLASMIC ANTIBODY; TUMOR NECROSIS FACTOR; IL1B PROTEIN, RAT; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA CONVERTING ENZYME; LIPOPOLYSACCHARIDE; NLRP3 PROTEIN, RAT;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CECAL LIGATION AND PUNCTURE-INDUCED SEPSIS; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; KIDNEY BIOPSY; KIDNEY FUNCTION; KIDNEY HYPERTROPHY; LUNG EDEMA; LUNG INJURY; MALE; MUCORMYCOSIS; NONHUMAN; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SEPSIS; TACHYCARDIA; THROMBOCYTE ACTIVATION; TUNEL ASSAY; WESTERN BLOTTING; ANIMAL; BLOOD; CAPILLARY PERMEABILITY; CECUM; CELL CULTURE; COMPLICATION; DRUG EFFECT; KIDNEY; LIGATION; LUNG; METABOLISM; MULTIPLE ORGAN FAILURE; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; SURGERY; THROMBOCYTE; VASCULAR ENDOTHELIUM;

ANIMALS; BLOOD PLATELETS; CAPILLARY PERMEABILITY; CASPASE 1; CECUM; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; INFLAMMASOMES; INTERLEUKIN-18; INTERLEUKIN-1BETA; KIDNEY; LIGATION; LIPOPOLYSACCHARIDES; LUNG; MALE; MULTIPLE ORGAN FAILURE; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; PLATELET ACTIVATION; RATS, SPRAGUE-DAWLEY; SEPSIS;

EID: 85065639501     PISSN: None     EISSN: 2051817X     Source Type: Journal    
DOI: 10.14814/phy2.14073     Document Type: Article

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