Platelet function in septic multiple organ dysfunction syndrome

Intensive Care Medicine

Volumn 23, Issue 4, 1997, Pages 379-385

  Gawaz, M ^a   Dickfeld, T ^a   Bogner, C ^a   Fateh Moghadam, S ^a   Neumann, F J ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Adhesion; Aggregation; Endothelium; Glycoproteins; Multiple organ dysfunction syndrome; Platelet; Sepsis

Indexed keywords

FIBRINOGEN; FIBRINOGEN RECEPTOR; THROMBOSPONDIN;

ADULT; AGED; ARTICLE; BLOOD CLOTTING PARAMETERS; CELL ADHESION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ENDOTHELIUM CELL; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INTENSIVE CARE UNIT; MALE; MULTIPLE ORGAN FAILURE; NEUTROPHIL; PROGNOSIS; REGRESSION ANALYSIS; SCORING SYSTEM; SEPSIS; THROMBOCYTE ADHESIVENESS; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION; TIME;

ADULT; AGED; APACHE; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CELL ADHESION MOLECULES; CROSS-SECTIONAL STUDIES; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; INTENSIVE CARE UNITS; LOGISTIC MODELS; MALE; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; MULTIPLE ORGAN FAILURE; NEUTROPHILS; PLATELET ACTIVATION; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROSPECTIVE STUDIES; SURVIVORS; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; THROMBOSPONDINS;

EID: 0030910382     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001340050344     Document Type: Article

References (41)

1. Roy C, Dorinsky PM (1994) Multiple organ dysfunction syndrome: pathogenesis and approach to therapy. Semin Respir Crit Care Med 15:325-334
2. Parrillo JE, Parker MM, Natanson C, Suffredini AF, Danner RL, Connion RE, Ognigene FP (1990) Septic shock in humans. Advances in the understanding of pathogenesis, cardiovascular dysfunction and therapy. Ann Intern Med 113:227-242
3. Neame PB, Kelton JG, Walker IR, Stewart IO, Nossel HL, Hirsh J (1980) Thrombocytopenia in septicemia: the role of disseminated intravascular coagulation. Blood 56:88-92
4. Heffner JE, Sahn SA, Repine JE (1987) The role of platelets in adult respiratory distress syndrome. Ann Rev Respir Dis 135:482-492
5. Saba TM, Fortune JB, Wallace JR (1992) Microaggregation hypothesis of multiple organ failure. In: DE Frey (ed) Multiple system organ failure-pathogenesis and management. Mosby, St. Louis, pp 115-122
6. Gawaz M, Fateh-Moghadam S, Pilz G, Gurland HJ, Werdan K (1995) Severity of multiple organ failure but not of sepsis correlates with irreversible platelet degranulation. Infection 23:16-23
7. Schneider RC, Zapol WM, Carvalho AC (1980) Platelet consumption and sequestration in severe acute respiratory distress syndrome. Am Rev Respir Dis 122:445-451
8. Kelton JG, Neame PB, Gauldie J, Hirsh J (1979) Elevated platelet-associated IgG in the thrombocytopenia of septicemia. N Engl J Med 300:760-764
9. Heffner JE, Repine JE (1991) Platelets. In: Crytal RG, West JB, Bamer PJ et al. (eds). The Lung: Scientific Foundations, Vol I. Raven Press, New York, pp 617-630
10. George JN, Nurden AT, Phillips DR (1984) Molecular defects in interactions of platelets with the vessel wall. N Engl J Med 311:1084-1098
11. Ginsberg MH, Loftus JC, Plow E (1988) Cytoadhesins, integrins, and platelets. Thromb Haemost 59:1-6
12. McEver RP (1990) The clinical significance of platelet membrane glycoproteins. Hematol Oncol Clin North Am 4:87-103
13. Gawaz MP, Loftus JC, Bajt ML, Frojmovic MM, Plow EF, Ginsberg MH (1991) Ligand bridging mediates integrin aIIbb3 (platelet GPIIb-IlIa) dependent homotypic and heterotypic cell-cell interactions. J Clin Invest 88:1128-1134
14. Frojmovic MM, O'Toole TE, Plow EF, Loftus JC, Ginsberg MH (1991) Platelet GPIIb-IIIa alpha IIb beta 3 integrin) confers fibrinogen and activation dependent aggregation on heterologous cells. Blood 78:369-376
15. Plow EF, Ginsberg MH (1989) Cellular adhesion: GPIIb-IIIa as a prototypic adhesion receptor. In: BS Coller (ed) Progress in Hemostasis and Thrombosis. Saunders, Philadelphia, pp 117-156
16. Leung L, Nachman R (1986) Molecular mechanism of platelet aggregation. Ann Rev Med 37:179-186
17. Asch AS, Nachman RL (1989) Thrombosponding: phenomenology to function. Prog Hemost Thromb 9:157-176
18. Pilz G, Gurniak T, Bujdoso O, Werdan K (1991) A BASIC program for calculation of APACHE II and Elebute scores and sepcis evaluation in intensive care medicine. Comput Biol Med 21:143-159
19. Grundmann R, Kipping N, Wesoly C (1988) Der Sepsisscore von Elebute und Stoner zur Definition der postoperativen Sepsis auf der Intensivstation. Intensiv-medizin 25:265-268
20. Knaus WA, Draper EA, Wagner DP, Zimmerman JE (1985) APACHE II: a severity of disease classification system. Crit Care Med 13:818-829
21. Elebute EA, Stoner HB (1983) The grading of sepsis. Br J Surg 70:29-31
22. Gawaz MP, Mujais SK, Schmidt B, Gurland HJ (1994) Platelet-leukocyte aggregation during hemodialysis. Kidney Int 46:489-495
23. Gawaz MP, Dobos G, Späth M, Mujais S (1994) Impaired function of platelet membrane glycoprotein IIb-IIIa in end-stage renal disease. J Am Soc Nephrol 5:36-46
24. Gawaz M, Neumann FJ, Ott I, Schiessler A, Schömig A (1996) Platelet function in acute myocardial infarction treated with direct angioplasty. Circulation 93:229-237
25. Gawaz M, Ott I, Reininger AJ, Heinzmann U, Neumann FJ (1996) Agglutination of isolated platelet membranes. Arterioscler Thromb Vasc Biol 16:621-627
26. Gawaz MP, Bogner C (1994) Changes in platelet membrane glycoproteins and platelet-leukocyte interaction during hemodialysis. Clin Invest 72:424-429
27. Gawaz M, Ott I, Reiniger AJ, Neumann FJ (1994) Effects of magnesium on platelet aggregation and adhesion. Magnesium modulates surface expression of glycoproteins on platelets in vitro and ex vivo. Thromb Haemost 72:912-918
28. Gawaz M, Mayinger P, Neumann FJ (1994) Effect of ATP in ligand recognition of platelet fibrinogen receptor on GPIIb-IIIa. Am J Physiol 267:H1098-1106
29. Rinder CS. Bonan JL, Rinder HM, Mathew J, Mines R, Smith BR (1992) Cardiopulmonary bypass induces leukocyte-platelet adhesion. Blood 79:1201-1205
30. Jaffe EA, Nachman RL, Becker CG, Minich CR (1973) Culture of human endothelial cells derived from umbilical veins. J Clin Invest 52:2745-2752
31. Ginsberg MH, Frelinger AL, Lam SCT, Forsyth J. McMillan R, Plow EF, Shattil SJ (1990) Analysis of platelet aggregation disorders based on flow cytometric analysis of membrane glycoprotein IIb-IIIa with conformation-specific monoclonal antibodies. Blood 76:2017-2023
32. Page CP (1989) Platelets as inflammatory cells. Immunopharmacology 17:;51-59
33. Pancre V, Joseph M, Mazingue C, Wietzerbin J, Capron A, Auriault C (1987) Induction of platelet cytotoxic functions by lymphokines: role of interferon gamma. J Immunol 138:4485-1490
34. Siess W (1989) Molecular mechanisms of platelet activation. Physiol Rev 69:50-178
35. Diez FL, Nieto ML, Fernandez-Gallardo S, Gijon MA, Crespo MS (1989) Occupancy of platelet receptors for platelet-activating factor in patients with septicemia. J Clin Invest 83:1733-1740
36. Faint RW (1992) Platelet-neutrophil interactions: their significance. Blood Rev 6:83-91
37. Hamburger SA, McEver RP (1990) GMP-140 mediates adhesion of stimulated platelets to neutrophils. Blood 75:550-555
38. Spangenberg P, Redlich H, Bergmenn I, Lösche W, Götzrath M, Kehrel B (1993) The platelet glyeoprotein IIb-IIIa complex is involved in the adhesion of activated platelets to leukocytes. Thromb Haemost 70:514-521
39. Bazzoni G, Dejana E, DelMaschio A (1991) Platelet-neutrophil interactions. Possible relevance in the pathogenesis of thrombosis and inflammation. Haematologica 76:491-499
40. Schirmer WJ, Fry DE (1992) Microcirculatory arrest. In: DE Frey (ed) Multiple Mosby, St. Louis, pp 123-128
41. Palabrica T, Lobb R, Furie BC, Aronovitz M, Benjamin C, Hsu YM, Sajer SA. Furie B (1992) Leukocyte accumulation promoting fibrin deposition is mediated in vivo by P-selection on adherent platelets. Nature 359:848-851