A Weaning Reaction to Microbiota Is Required for Resistance to Immunopathologies in the Adult

Immunity

Volumn 50, Issue 5, 2019, Pages 1276-1288.e5

  Al Nabhani, Ziad ^a,b   Dulauroy, Sophie ^a,b   Marques, Rute ^a,b   Cousu, Clara ^a,b   Al Bounny, Shahed ^a,b   Déjardin, François ^a,b   Sparwasser, Tim ^c   Bérard, Marion ^a   Cerf Bensussan, Nadine ^d,e   Eberl, Gérard ^a,b  

^a INSTITUT PASTEUR   (France)

^b INSERM   (France)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

^d IMAGINE INSTITUTE   (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

colitis; inflammatory pathology; microbiota; mucosal immunity; neonatal period; regulatory T cells; short chain fatty acids; weaning

Indexed keywords

ANTIBIOTIC AGENT; GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 5; TUMOR NECROSIS FACTOR; RETINOIC ACID; RETINOID RELATED ORPHAN RECEPTOR GAMMA; RORC PROTEIN, MOUSE; VOLATILE FATTY ACID;

ADULT; ARTICLE; COLITIS; CONTROLLED STUDY; FEMALE; IMMUNE RESPONSE; IMMUNOPATHOLOGY; INTESTINE FLORA; MALE; MOLECULAR IMPRINTING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; WEANING; ANIMAL; C57BL MOUSE; IMMUNOLOGY; INTESTINE MUCOSA; METABOLISM; MICROBIOLOGY; NEWBORN;

ANIMALS; ANIMALS, NEWBORN; FATTY ACIDS, VOLATILE; GASTROINTESTINAL MICROBIOME; INTESTINAL MUCOSA; MICE; MICE, INBRED C57BL; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 3; T-LYMPHOCYTES, REGULATORY; TRETINOIN; WEANING;

EID: 85064937503     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2019.02.014     Document Type: Article

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