메뉴 건너뛰기




Volumn 163, Issue , 2019, Pages 75-88

Identification of a UDP-Glucosyltransferase favouring substrate- and regio-specific biosynthesis of flavonoid glucosides in Cyclocarya paliurus

Author keywords

C. paliurus GT1; Cyclocarya paliurus; Flavonoid; Glucosylation; Juglandaceae; Mutagenesis; UDP Glucosyltransferase

Indexed keywords

FLAVONOID; GLUCOSIDE; GLUCOSYLTRANSFERASE;

EID: 85064826273     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phytochem.2019.04.004     Document Type: Article
Times cited : (17)

References (38)
  • 2
    • 84955257512 scopus 로고    scopus 로고
    • Diversity of sugar acceptor of glycosyltransferase 1 from Bacillus cereus and its application for glucoside synthesis
    • Chiu, H.H., Shen, M.Y., Liu, Y.T., Fu, Y.L., Chiu, Y.A., Chen, Y.H., Huang, C.P., Li, Y.K., Diversity of sugar acceptor of glycosyltransferase 1 from Bacillus cereus and its application for glucoside synthesis. Appl. Microbiol. Biotechnol. 100 (2016), 4459–4471.
    • (2016) Appl. Microbiol. Biotechnol. , vol.100 , pp. 4459-4471
    • Chiu, H.H.1    Shen, M.Y.2    Liu, Y.T.3    Fu, Y.L.4    Chiu, Y.A.5    Chen, Y.H.6    Huang, C.P.7    Li, Y.K.8
  • 3
    • 84963851480 scopus 로고    scopus 로고
    • Identification of UDP-glycosyltransferases involved in the biosynthesis of astringent taste compounds in tea (Camellia sinensis)
    • Cui, L., Yao, S., Dai, X., Yin, Q., Liu, Y., Jiang, X., Wu, Y., Qian, Y., Pang, Y., Gao, L., Xia, T., Identification of UDP-glycosyltransferases involved in the biosynthesis of astringent taste compounds in tea (Camellia sinensis). J. Exp. Bot. 67 (2016), 2285–2297.
    • (2016) J. Exp. Bot. , vol.67 , pp. 2285-2297
    • Cui, L.1    Yao, S.2    Dai, X.3    Yin, Q.4    Liu, Y.5    Jiang, X.6    Wu, Y.7    Qian, Y.8    Pang, Y.9    Gao, L.10    Xia, T.11
  • 4
    • 84924521776 scopus 로고    scopus 로고
    • Biotechnological advances in UDP-sugar based glycosylation of small molecules
    • De Bruyn, F., Maertens, J., Beauprez, J., Soetaert, W., De Mey, M., Biotechnological advances in UDP-sugar based glycosylation of small molecules. Biotechnol. Adv. 33 (2015), 288–302.
    • (2015) Biotechnol. Adv. , vol.33 , pp. 288-302
    • De Bruyn, F.1    Maertens, J.2    Beauprez, J.3    Soetaert, W.4    De Mey, M.5
  • 5
    • 84862872858 scopus 로고    scopus 로고
    • Integrated effects of light intensity and fertilization on growth and flavonoid accumulation in Cyclocarya paliurus
    • Deng, B., Shang, X., Fang, S., Li, Q., Fu, X., Su, J., Integrated effects of light intensity and fertilization on growth and flavonoid accumulation in Cyclocarya paliurus. J. Agric. Food Chem. 60 (2012), 6286–6292.
    • (2012) J. Agric. Food Chem. , vol.60 , pp. 6286-6292
    • Deng, B.1    Shang, X.2    Fang, S.3    Li, Q.4    Fu, X.5    Su, J.6
  • 6
    • 85044991408 scopus 로고    scopus 로고
    • Switching glycosyltransferase UGT(BL)1 regioselectivity toward polydatin synthesis using a semi-rational design
    • Fan, B., Dong, W.X., Chen, T.Y., Chu, J.L., He, B.F., Switching glycosyltransferase UGT(BL)1 regioselectivity toward polydatin synthesis using a semi-rational design. Org. Biomol. Chem. 16 (2018), 2464–2469.
    • (2018) Org. Biomol. Chem. , vol.16 , pp. 2464-2469
    • Fan, B.1    Dong, W.X.2    Chen, T.Y.3    Chu, J.L.4    He, B.F.5
  • 7
    • 84903311460 scopus 로고    scopus 로고
    • Comparative analysis of Arabidopsis UGT74 glucosyltransferases reveals a special role of UGT74C1 in glucosinolate biosynthesis
    • Grubb, C.D., Zipp, B.J., Kopycki, J., Schubert, M., Quint, M., Lim, E.K., Bowles, D.J., Pedras, M.S.C., Abel, S., Comparative analysis of Arabidopsis UGT74 glucosyltransferases reveals a special role of UGT74C1 in glucosinolate biosynthesis. Plant J. 79 (2014), 92–105.
    • (2014) Plant J. , vol.79 , pp. 92-105
    • Grubb, C.D.1    Zipp, B.J.2    Kopycki, J.3    Schubert, M.4    Quint, M.5    Lim, E.K.6    Bowles, D.J.7    Pedras, M.S.C.8    Abel, S.9
  • 8
    • 3843126366 scopus 로고    scopus 로고
    • Site-directed mutagenesis and protein 3D-homology modelling suggest a catalytic mechanism for UDP-glucose-dependent betanidin 5-O-glucosyltransferase from Dorotheanthus bellidiformis
    • Hans, J., Brandt, W., Vogt, T., Site-directed mutagenesis and protein 3D-homology modelling suggest a catalytic mechanism for UDP-glucose-dependent betanidin 5-O-glucosyltransferase from Dorotheanthus bellidiformis. Plant J.: Cell Cult. Methods Mol. Cell Biol. 39 (2004), 319–333.
    • (2004) Plant J.: Cell Cult. Methods Mol. Cell Biol. , vol.39 , pp. 319-333
    • Hans, J.1    Brandt, W.2    Vogt, T.3
  • 9
    • 33845928213 scopus 로고    scopus 로고
    • Mutational analysis of the Medicago glycosyltransferase UGT71G1 reveals residues that control regioselectivity for (iso)flavonoid glycosylation
    • He, X.Z., Wang, X., Dixon, R.A., Mutational analysis of the Medicago glycosyltransferase UGT71G1 reveals residues that control regioselectivity for (iso)flavonoid glycosylation. J. Biol. Chem. 281 (2006), 34441–34447.
    • (2006) J. Biol. Chem. , vol.281 , pp. 34441-34447
    • He, X.Z.1    Wang, X.2    Dixon, R.A.3
  • 10
    • 85020194224 scopus 로고    scopus 로고
    • Flavones: food sources, bioavailability, metabolism, and bioactivity
    • Hostetler, G.L., Ralston, R.A., Schwartz, S.J., Flavones: food sources, bioavailability, metabolism, and bioactivity. Adv. Nutr. 8 (2017), 423–435.
    • (2017) Adv. Nutr. , vol.8 , pp. 423-435
    • Hostetler, G.L.1    Ralston, R.A.2    Schwartz, S.J.3
  • 12
    • 85010952315 scopus 로고    scopus 로고
    • Functional foods and dietary supplements for the management of dyslipidaemia
    • Hunter, P.M., Hegele, R.A., Functional foods and dietary supplements for the management of dyslipidaemia. Nat. Rev. Endocrinol. 13 (2017), 278–288.
    • (2017) Nat. Rev. Endocrinol. , vol.13 , pp. 278-288
    • Hunter, P.M.1    Hegele, R.A.2
  • 13
    • 85033404752 scopus 로고    scopus 로고
    • Mechanisms of dietary flavonoid action in neuronal function and neuroinflammation
    • Jaeger, B.N., Parylak, S.L., Gage, F.H., Mechanisms of dietary flavonoid action in neuronal function and neuroinflammation. Mol. Aspect. Med. 61 (2018), 50–62.
    • (2018) Mol. Aspect. Med. , vol.61 , pp. 50-62
    • Jaeger, B.N.1    Parylak, S.L.2    Gage, F.H.3
  • 14
    • 85024404703 scopus 로고    scopus 로고
    • Isolation, structure, and bioactivities of polysaccharides from Cyclocarya paliurus (Batal.)Iljinskaja
    • Li, Q.Q., Hu, J.L., Xie, J.H., Nie, S.P., Xie, M.Y., Isolation, structure, and bioactivities of polysaccharides from Cyclocarya paliurus (Batal.)Iljinskaja. Ann. Ny. Acad. Sci. 1398 (2017), 20–29.
    • (2017) Ann. Ny. Acad. Sci. , vol.1398 , pp. 20-29
    • Li, Q.Q.1    Hu, J.L.2    Xie, J.H.3    Nie, S.P.4    Xie, M.Y.5
  • 15
    • 85053769378 scopus 로고    scopus 로고
    • Geographic variation in the chemical composition and antioxidant properties of phenolic compounds from Cyclocarya paliurus (batal)iljinskaja leaves
    • Liu, Y., Chen, P., Zhou, M., Wang, T., Fang, S., Shang, X., Fu, X., Geographic variation in the chemical composition and antioxidant properties of phenolic compounds from Cyclocarya paliurus (batal)iljinskaja leaves. Molecules, 23, 2018.
    • (2018) Molecules , vol.23
    • Liu, Y.1    Chen, P.2    Zhou, M.3    Wang, T.4    Fang, S.5    Shang, X.6    Fu, X.7
  • 16
    • 85052331071 scopus 로고    scopus 로고
    • Characterization of UDP-glycosyltransferase involved in biosynthesis of ginsenosides Rg1 and Rb1 and identification of critical conserved amino acid residues for its function
    • Lu, J., Yao, L., Li, J.X., Liu, S.J., Hu, Y.Y., Wang, S.H., Liang, W.X., Huang, L.Q., Dai, Y.J., Wang, J., Gao, W.Y., Characterization of UDP-glycosyltransferase involved in biosynthesis of ginsenosides Rg1 and Rb1 and identification of critical conserved amino acid residues for its function. J. Agric. Food Chem. 66 (2018), 9446–9455.
    • (2018) J. Agric. Food Chem. , vol.66 , pp. 9446-9455
    • Lu, J.1    Yao, L.2    Li, J.X.3    Liu, S.J.4    Hu, Y.Y.5    Wang, S.H.6    Liang, W.X.7    Huang, L.Q.8    Dai, Y.J.9    Wang, J.10    Gao, W.Y.11
  • 17
    • 67349243007 scopus 로고    scopus 로고
    • Single amino acid mutations of Medicago glycosyltransferase UGT85H2 enhance activity and impart reversibility
    • Modolo, L.V., Escamilla-Trevino, L.L., Dixon, R.A., Wang, X., Single amino acid mutations of Medicago glycosyltransferase UGT85H2 enhance activity and impart reversibility. FEBS Lett. 583 (2009), 2131–2135.
    • (2009) FEBS Lett. , vol.583 , pp. 2131-2135
    • Modolo, L.V.1    Escamilla-Trevino, L.L.2    Dixon, R.A.3    Wang, X.4
  • 18
    • 70149104455 scopus 로고    scopus 로고
    • Crystal structures of glycosyltransferase UGT78G1 reveal the molecular basis for glycosylation and deglycosylation of (iso)flavonoids
    • Modolo, L.V., Li, L., Pan, H., Blount, J.W., Dixon, R.A., Wang, X., Crystal structures of glycosyltransferase UGT78G1 reveal the molecular basis for glycosylation and deglycosylation of (iso)flavonoids. J. Mol. Biol. 392 (2009), 1292–1302.
    • (2009) J. Mol. Biol. , vol.392 , pp. 1292-1302
    • Modolo, L.V.1    Li, L.2    Pan, H.3    Blount, J.W.4    Dixon, R.A.5    Wang, X.6
  • 21
    • 84904982281 scopus 로고    scopus 로고
    • Plant biology informs drug discovery
    • Rape, M., Plant biology informs drug discovery. Nat. Rev. Mol. Cell Biol., 15, 2014, 501.
    • (2014) Nat. Rev. Mol. Cell Biol. , vol.15 , pp. 501
    • Rape, M.1
  • 22
    • 84904790793 scopus 로고    scopus 로고
    • Deciphering key features in protein structures with the new ENDscript server
    • Robert, X., Gouet, P., Deciphering key features in protein structures with the new ENDscript server. Nucleic Acids Res. 42 (2014), W320–W324.
    • (2014) Nucleic Acids Res. , vol.42 , pp. W320-W324
    • Robert, X.1    Gouet, P.2
  • 23
    • 33645281589 scopus 로고    scopus 로고
    • Crystal structures of a multifunctional triterpene/flavonoid glycosyltransferase from Medicago truncatula
    • Shao, H., He, X., Achnine, L., Blount, J.W., Dixon, R.A., Wang, X., Crystal structures of a multifunctional triterpene/flavonoid glycosyltransferase from Medicago truncatula. Plant Cell 17 (2005), 3141–3154.
    • (2005) Plant Cell , vol.17 , pp. 3141-3154
    • Shao, H.1    He, X.2    Achnine, L.3    Blount, J.W.4    Dixon, R.A.5    Wang, X.6
  • 24
    • 84975450279 scopus 로고    scopus 로고
    • Exploring the molecular targets of dietary flavonoid fisetin in cancer
    • Syed, D.N., Adhami, V.M., Khan, N., Khan, M.I., Mukhtar, H., Exploring the molecular targets of dietary flavonoid fisetin in cancer. Semin. Canc. Biol. 40–41 (2016), 130–140.
    • (2016) Semin. Canc. Biol. , vol.40-41 , pp. 130-140
    • Syed, D.N.1    Adhami, V.M.2    Khan, N.3    Khan, M.I.4    Mukhtar, H.5
  • 25
    • 84964671781 scopus 로고    scopus 로고
    • Plant secondary metabolism linked glycosyltransferases: an update on expanding knowledge and scopes
    • Tiwari, P., Sangwan, R.S., Sangwan, N.S., Plant secondary metabolism linked glycosyltransferases: an update on expanding knowledge and scopes. Biotechnol. Adv. 34 (2016), 714–739.
    • (2016) Biotechnol. Adv. , vol.34 , pp. 714-739
    • Tiwari, P.1    Sangwan, R.S.2    Sangwan, N.S.3
  • 26
    • 76149120388 scopus 로고    scopus 로고
    • AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
    • Trott, O., Olson, A.J., AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. J. Comput. Chem. 31 (2010), 455–461.
    • (2010) J. Comput. Chem. , vol.31 , pp. 455-461
    • Trott, O.1    Olson, A.J.2
  • 28
    • 84886867848 scopus 로고    scopus 로고
    • Realizing the promise of chemical glycobiology
    • Wang, L.X., Davis, B.G., Realizing the promise of chemical glycobiology. Chem. Sci. 4 (2013), 3381–3394.
    • (2013) Chem. Sci. , vol.4 , pp. 3381-3394
    • Wang, L.X.1    Davis, B.G.2
  • 29
    • 70349850632 scopus 로고    scopus 로고
    • Structure, mechanism and engineering of plant natural product glycosyltransferases
    • Wang, X., Structure, mechanism and engineering of plant natural product glycosyltransferases. FEBS Lett. 583 (2009), 3303–3309.
    • (2009) FEBS Lett. , vol.583 , pp. 3303-3309
    • Wang, X.1
  • 30
    • 79952987606 scopus 로고    scopus 로고
    • Structure, function, and engineering of enzymes in isoflavonoid biosynthesis
    • Wang, X., Structure, function, and engineering of enzymes in isoflavonoid biosynthesis. Funct. Integr. Genom. 11 (2011), 13–22.
    • (2011) Funct. Integr. Genom. , vol.11 , pp. 13-22
    • Wang, X.1
  • 31
    • 85016474340 scopus 로고    scopus 로고
    • Molecular characterization of the C-glucosylation for puerarin biosynthesis in Pueraria lobata
    • Wang, X., Li, C., Zhou, C., Li, J., Zhang, Y., Molecular characterization of the C-glucosylation for puerarin biosynthesis in Pueraria lobata. Plant J.: Cell Cult. Methods Mol. Cell Biol. 90 (2017), 535–546.
    • (2017) Plant J.: Cell Cult. Methods Mol. Cell Biol. , vol.90 , pp. 535-546
    • Wang, X.1    Li, C.2    Zhou, C.3    Li, J.4    Zhang, Y.5
  • 32
    • 85057206768 scopus 로고    scopus 로고
    • PgUGT95B2 preferentially metabolizes flavones/flavonols and has evolved independently from flavone/flavonol UGTs identified in Arabidopsis thaliana
    • Wilson, A.E., Wu, S., Tian, L., PgUGT95B2 preferentially metabolizes flavones/flavonols and has evolved independently from flavone/flavonol UGTs identified in Arabidopsis thaliana. Phytochemistry 157 (2018), 184–193.
    • (2018) Phytochemistry , vol.157 , pp. 184-193
    • Wilson, A.E.1    Wu, S.2    Tian, L.3
  • 33
    • 85027995532 scopus 로고    scopus 로고
    • Cyclocarya paliurus tea leaves enhances pancreatic beta cell preservation through inhibition of apoptosis
    • Xiao, H.T., Wen, B., Ning, Z.W., Zhai, L.X., Liao, C.H., Lin, C.Y., Mu, H.X., Bian, Z.X., Cyclocarya paliurus tea leaves enhances pancreatic beta cell preservation through inhibition of apoptosis. Sci. Rep., 7, 2017, 9155.
    • (2017) Sci. Rep. , vol.7 , pp. 9155
    • Xiao, H.T.1    Wen, B.2    Ning, Z.W.3    Zhai, L.X.4    Liao, C.H.5    Lin, C.Y.6    Mu, H.X.7    Bian, Z.X.8
  • 34
    • 84929522948 scopus 로고    scopus 로고
    • Extraction, chemical composition and antioxidant activity of flavonoids from Cyclocarya paliurus (Batal.)Iljinskaja leaves
    • Xie, J.H., Dong, C.J., Nie, S.P., Li, F., Wang, Z.J., Shen, M.Y., Xie, M.Y., Extraction, chemical composition and antioxidant activity of flavonoids from Cyclocarya paliurus (Batal.)Iljinskaja leaves. Food Chem. 186 (2015), 97–105.
    • (2015) Food Chem. , vol.186 , pp. 97-105
    • Xie, J.H.1    Dong, C.J.2    Nie, S.P.3    Li, F.4    Wang, Z.J.5    Shen, M.Y.6    Xie, M.Y.7
  • 35
    • 84982102829 scopus 로고    scopus 로고
    • De novo transcriptome assembly and annotation of the leaves and callus of Cyclocarya paliurus (Bata1)iljinskaja
    • Xu, X., Yin, Z., Chen, J., Wang, X., Peng, D., Shangguan, X., De novo transcriptome assembly and annotation of the leaves and callus of Cyclocarya paliurus (Bata1)iljinskaja. PLoS One, 11, 2016, e0160279.
    • (2016) PLoS One , vol.11
    • Xu, X.1    Yin, Z.2    Chen, J.3    Wang, X.4    Peng, D.5    Shangguan, X.6
  • 36
    • 85017528852 scopus 로고    scopus 로고
    • Chemical fingerprint and determination of triterpenoids in cultured Cyclocarya paliurus cells by high-performance liquid chromatography
    • Yin, Z.P., Xiong, Q.Q., Shang-Guan, X.C., Chen, J.G., Chemical fingerprint and determination of triterpenoids in cultured Cyclocarya paliurus cells by high-performance liquid chromatography. Anal. Lett. 50 (2017), 748–760.
    • (2017) Anal. Lett. , vol.50 , pp. 748-760
    • Yin, Z.P.1    Xiong, Q.Q.2    Shang-Guan, X.C.3    Chen, J.G.4
  • 37
    • 85052818119 scopus 로고    scopus 로고
    • Cyclocarya paliurus leaves tea improves dyslipidemia in diabetic mice: a lipidomics-based network pharmacology study
    • Zhai, L., Ning, Z.W., Huang, T., Wen, B., Liao, C.H., Lin, C.Y., Zhao, L., Xiao, H.T., Bian, Z.X., Cyclocarya paliurus leaves tea improves dyslipidemia in diabetic mice: a lipidomics-based network pharmacology study. Front. Pharmacol., 9, 2018, 973.
    • (2018) Front. Pharmacol. , vol.9 , pp. 973
    • Zhai, L.1    Ning, Z.W.2    Huang, T.3    Wen, B.4    Liao, C.H.5    Lin, C.Y.6    Zhao, L.7    Xiao, H.T.8    Bian, Z.X.9
  • 38
    • 85056159108 scopus 로고    scopus 로고
    • The influence of C2C3 double bond on the antiradical activity of flavonoid: different mechanisms analysis
    • Zheng, Y.Z., Deng, G., Chen, D.F., Guo, R., Lai, R.C., The influence of C2C3 double bond on the antiradical activity of flavonoid: different mechanisms analysis. Phytochemistry 157 (2018), 1–7.
    • (2018) Phytochemistry , vol.157 , pp. 1-7
    • Zheng, Y.Z.1    Deng, G.2    Chen, D.F.3    Guo, R.4    Lai, R.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.