Canagliflozin Prevents Intrarenal Angiotensinogen Augmentation and Mitigates Kidney Injury and Hypertension in Mouse Model of Type 2 Diabetes Mellitus

American Journal of Nephrology

Volumn 49, Issue 4, 2019, Pages 331-341

  Woods, T Cooper ^a   Satou, Ryousuke ^a   Miyata, Kayoko ^a   Katsurada, Akemi ^a   Dugas, Courtney M ^a   Klingenberg, Natasha C ^a   Fonseca, Vivian A ^a   Navar, L Gabriel ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Angiotensinogen; Blood pressure; Diabetes mellitus; Kidney; Sodium glucose cotransporter 2 inhibition

Indexed keywords

8 ISOPROSTANE; ANGIOTENSINOGEN; CANAGLIFLOZIN; POTASSIUM; SODIUM; SODIUM GLUCOSE COTRANSPORTER 2; AGT PROTEIN, MOUSE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL INFILTRATION; CELL PROLIFERATION; CONTROLLED STUDY; DIABETIC NEPHROPATHY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; HYPERTENSION; IMMUNOHISTOCHEMISTRY; KIDNEY INJURY; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; URINARY EXCRETION; WESTERN BLOTTING; ADMINISTRATION AND DOSAGE; ADVERSE EVENT; ANIMAL; BLOOD; BLOOD PRESSURE; COMPLICATION; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; FIBROSIS; HUMAN; IMMUNOLOGY; KIDNEY PROXIMAL TUBULE; LIPID DIET; METABOLISM; PATHOLOGY; UPREGULATION;

ANGIOTENSINOGEN; ANIMALS; BLOOD GLUCOSE; BLOOD PRESSURE; CANAGLIFLOZIN; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; DIET, HIGH-FAT; FIBROSIS; HUMANS; HYPERTENSION; KIDNEY TUBULES, PROXIMAL; MICE; OXIDATIVE STRESS; SODIUM-GLUCOSE TRANSPORTER 2 INHIBITORS; UP-REGULATION;

EID: 85063592622     PISSN: 02508095     EISSN: 14219670     Source Type: Journal    
DOI: 10.1159/000499597     Document Type: Article

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