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Volumn 11, Issue 11, 2016, Pages

Effect of sodium-glucose co-transporter 2 inhibitor, dapagliflozin, on renal renin-angiotensin system in an animal model of type 2 diabetes

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; ANGIOTENSINOGEN; CATALASE; COLLAGEN TYPE 4; COPPER ZINC SUPEROXIDE DISMUTASE; DAPAGLIFLOZIN; HEMOGLOBIN A1C; MANGANESE SUPEROXIDE DISMUTASE; RAS PROTEIN; RENIN; SODIUM GLUCOSE COTRANSPORTER 2; VOGLIBOSE; 2-(3-(4-ETHOXYBENZYL)-4-CHLOROPHENYL)-6-HYDROXYMETHYLTETRAHYDRO-2H-PYRAN-3,4,5-TRIOL; ALDOSTERONE; BENZHYDRYL DERIVATIVE; CHYMOSIN; GLUCOSIDE;

EID: 84993929544     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0165703     Document Type: Article
Times cited : (160)

References (49)
  • 1
    • 84906923900 scopus 로고    scopus 로고
    • Diabetic kidney disease: From epidemiology to clinical perspectives
    • PMID: 25215271
    • Park CW. Diabetic Kidney Disease: From epidemiology to clinical perspectives. Diabetes Metab J. 2014; 38(4):252-60. doi: 10.4093/dmj.2014.38.4.252 PMID: 25215271
    • (2014) Diabetes Metab J. , vol.38 , Issue.4 , pp. 252-260
    • Park, C.W.1
  • 2
    • 84957112175 scopus 로고    scopus 로고
    • The chronic kidney disease epidemiology collaboration equation improves the detection of hyperfiltration in Chinese diabetic patients
    • PMID: 26885183
    • Zhao F, Zhang L, Lu J., Guo K, Wu M, Yu H., et al. The Chronic Kidney Disease Epidemiology Collaboration equation improves the detection of hyperfiltration in Chinese diabetic patients. Int J Clin Exp Med. 2015; 8(12):22084-97. PMID: 26885183
    • (2015) Int J Clin Exp Med. , vol.8 , Issue.12 , pp. 22084-22097
    • Zhao, F.1    Zhang, L.2    Lu, J.3    Guo, K.4    Wu, M.5    Yu, H.6
  • 3
    • 84907879841 scopus 로고    scopus 로고
    • Comprehensive approach to diabetic nephropathy
    • PMID: 26894033
    • Satirapoj B, Adler SG Comprehensive approach to diabetic nephropathy. Kidney Res Clin Pract. 2014; 33(3):121-31. doi: 10.1016/j.krcp.2014.08.001 PMID: 26894033
    • (2014) Kidney Res Clin Pract. , vol.33 , Issue.3 , pp. 121-131
    • Satirapoj, B.1    Adler, S.G.2
  • 4
    • 84898602820 scopus 로고    scopus 로고
    • Changes in diabetes-related complications in the United States, 1990-2010
    • PMID: 24738668
    • Gregg EW, Li Y, Wang J., Burrows NR, Ali MK, Rolka D, et al Changes in diabetes-related complications in the United States, 1990-2010. N Engl J Med. 2014; 370(16):1514-23. doi: 10.1056/NEJMoa1310799 PMID: 24738668
    • (2014) N Engl J Med. , vol.370 , Issue.16 , pp. 1514-1523
    • Gregg, E.W.1    Li, Y.2    Wang, J.3    Burrows, N.R.4    Ali, M.K.5    Rolka, D.6
  • 5
    • 0027525040 scopus 로고
    • Renal renin-angiotensin system in diabetes: Functional, immuno-histochemical, and molecular biological correlations
    • Anderson S, Jung FF, Ingelfinger JR Renal renin-angiotensin system in diabetes: functional, immuno-histochemical, and molecular biological correlations. Am J Physiol. 1993; 265(4 Pt 2):F477-86.
    • (1993) Am J Physiol. , vol.265 , Issue.4 , pp. F477-F486
    • Anderson, S.1    Jung, F.F.2    Ingelfinger, J.R.3
  • 6
    • 84939888126 scopus 로고    scopus 로고
    • Inflammation in diabetic nephropathy: Moving toward clinical biomarkers and targets for treatment
    • PMID: 25273317
    • Barutta F, Bruno G, Grimaldi S., Gruden G. Inflammation in diabetic nephropathy: moving toward clinical biomarkers and targets for treatment. Endocrine. 2015; 48(3):730-42. doi: 10.1007/s12020-014-0437-1 PMID: 25273317
    • (2015) Endocrine. , vol.48 , Issue.3 , pp. 730-742
    • Barutta, F.1    Bruno, G.2    Grimaldi, S.3    Gruden, G.4
  • 7
    • 33745845825 scopus 로고    scopus 로고
    • Physiology of local renin-angiotensin systems
    • PMID: 16816138
    • Paul M, Poyan Mehr A, Kreutz R. Physiology of local renin-angiotensin systems. Physiol Rev. 2006; 86(3):747-803 doi: 10.1152/physrev.00036.2005 PMID: 16816138
    • (2006) Physiol Rev. , vol.86 , Issue.3 , pp. 747-803
    • Paul, M.1    Poyan Mehr, A.2    Kreutz, R.3
  • 8
    • 56149096807 scopus 로고    scopus 로고
    • AT2 receptors: Functional relevance in cardiovascular disease
    • PMID: 18804122
    • Jones ES, Vinh A, McCarthy C.A., Gaspari TA, Widdop RE. AT2 receptors: functional relevance in cardiovascular disease. Pharmacol Ther. 2008; 120(3):292-316. doi: 10.1016/j.pharmthera.2008.08.009 PMID: 18804122
    • (2008) Pharmacol Ther. , vol.120 , Issue.3 , pp. 292-316
    • Jones, E.S.1    Vinh, A.2    McCarthy, C.A.3    Gaspari, T.A.4    Widdop, R.E.5
  • 9
    • 0032733920 scopus 로고    scopus 로고
    • AT(2) receptor stimulation enhances antihypertensive effect of AT(1) receptor antagonist in hypertensive rats
    • PMID: 10567191
    • Barber MN, Sampey DB, Widdop RE AT(2) receptor stimulation enhances antihypertensive effect of AT(1) receptor antagonist in hypertensive rats. Hypertension. 1999; 34(5):1112-6. PMID: 10567191
    • (1999) Hypertension. , vol.34 , Issue.5 , pp. 1112-1116
    • Barber, M.N.1    Sampey, D.B.2    Widdop, R.E.3
  • 10
    • 70349984006 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-alpha activator fenofibrate prevents high-fat diet-induced renal lipotoxicity in spontaneously hypertensive rats
    • PMID: 19644507
    • Shin SJ, Lim JH, Chung S, Youn D.Y., Chung HW, Kim HW, et al. Peroxisome proliferator-activated receptor-alpha activator fenofibrate prevents high-fat diet-induced renal lipotoxicity in spontaneously hypertensive rats. Hypertens Res. 2009; 32(10):835-45. doi: 10.1038/hr.2009.107 PMID: 19644507
    • (2009) Hypertens Res. , vol.32 , Issue.10 , pp. 835-845
    • Shin, S.J.1    Lim, J.H.2    Chung, S.3    Youn, D.Y.4    Chung, H.W.5    Kim, H.W.6
  • 11
    • 34047247353 scopus 로고    scopus 로고
    • The renin-angiotensin system and diabetic nephropathy
    • PMID: 17418683
    • Gurley SB, Coffman TM The renin-angiotensin system and diabetic nephropathy. Semin Nephrol. 2007; 27(2):144-52. doi: 10.1016/j.semnephrol.2007.01.009 PMID: 17418683
    • (2007) Semin Nephrol. , vol.27 , Issue.2 , pp. 144-152
    • Gurley, S.B.1    Coffman, T.M.2
  • 12
    • 44949105469 scopus 로고    scopus 로고
    • Activation of a local renin angiotensin system in podocytes by glucose
    • PMID: 18216149
    • Durvasula RV, Shankland SJ Activation of a local renin angiotensin system in podocytes by glucose. Am J Physiol Renal Physiol. 2008; 294(4):F830-9. doi: 10.1152/ajprenal.00266.2007 PMID: 18216149
    • (2008) Am J Physiol Renal Physiol. , vol.294 , Issue.4 , pp. F830-F839
    • Durvasula, R.V.1    Shankland, S.J.2
  • 13
    • 79958143772 scopus 로고    scopus 로고
    • Attenuating effect of angio-tensin-(1-7) on angiotensin II-mediated NAD(P)H oxidase activation in type 2 diabetic nephropathy of KK-A(y)/Ta mice
    • PMID: 21367916
    • Moon JY, Tanimoto M, Gohda T, Hagiwara S, Yamazaki T, Ohara I, et al. Attenuating effect of angio-tensin-(1-7) on angiotensin II-mediated NAD(P)H oxidase activation in type 2 diabetic nephropathy of KK-A(y)/Ta mice. Am J Physiol Renal Physiol. 2011; 300(6):F1271-82. doi: 10.1152/ajprenal.00065.2010 PMID: 21367916
    • (2011) Am J Physiol Renal Physiol. , vol.300 , Issue.6 , pp. F1271-F1282
    • Moon, J.Y.1    Tanimoto, M.2    Gohda, T.3    Hagiwara, S.4    Yamazaki, T.5    Ohara, I.6
  • 14
    • 70350211835 scopus 로고    scopus 로고
    • Mechanism of VEGF expression by high glucose in proximal tubule epithelial cells
    • PMID: 19765632
    • Feliers D, Kasinath BS Mechanism of VEGF expression by high glucose in proximal tubule epithelial cells. Mol Cell Endocrinol. 2010; 314(1):136-42. doi: 10.1016/j.mce.2009.09.009 PMID: 19765632
    • (2010) Mol Cell Endocrinol. , vol.314 , Issue.1 , pp. 136-142
    • Feliers, D.1    Kasinath, B.S.2
  • 15
    • 84877873824 scopus 로고    scopus 로고
    • Aberrant activation of the intrarenal renin-angiotensin system in the developing kidneys of type 2 diabetic rats
    • PMID: 23322513
    • Fan YY, Kobori H, Nakano D., Hitomi H, Mori H, Masaki T, et al. Aberrant activation of the intrarenal renin-angiotensin system in the developing kidneys of type 2 diabetic rats. Horm Metab Res. 2013; 45 (5):338-43. doi: 10.1055/s-0032-1331256 PMID: 23322513
    • (2013) Horm Metab Res. , vol.45 , Issue.5 , pp. 338-343
    • Fan, Y.Y.1    Kobori, H.2    Nakano, D.3    Hitomi, H.4    Mori, H.5    Masaki, T.6
  • 16
    • 77954242599 scopus 로고    scopus 로고
    • SGLT2 inhibition - A novel strategy for diabetes treatment
    • PMID: 20508640
    • Chao EC, Henry RR SGLT2 inhibition-a novel strategy for diabetes treatment. Nat Rev Drug Discov. 2010; 9(7):551-9. doi: 10.1038/nrd3180 PMID: 20508640
    • (2010) Nat Rev Drug Discov. , vol.9 , Issue.7 , pp. 551-559
    • Chao, E.C.1    Henry, R.R.2
  • 17
    • 84906923912 scopus 로고    scopus 로고
    • A novel therapeutic agent for type 2 diabetes mellitus: Sglt2 inhibitor
    • PMID: 25215272
    • Jung CH, Jang JE, Park JY A Novel Therapeutic Agent for Type 2 Diabetes Mellitus: SGLT2 Inhibitor. Diabetes Metab J. 2014; 38(4):261-73. doi: 10.4093/dmj.2014.38.4.261 PMID: 25215272
    • (2014) Diabetes Metab J. , vol.38 , Issue.4 , pp. 261-273
    • Jung, C.H.1    Jang, J.E.2    Park, J.Y.3
  • 18
    • 84880012343 scopus 로고    scopus 로고
    • Sodium-glucose cotransporter inhibition: Therapeutic potential for the treatment of type 2 diabetes mellitus
    • PMID: 23463735
    • Raskin P. Sodium-glucose cotransporter inhibition: therapeutic potential for the treatment of type 2 diabetes mellitus. Diabetes Metab Res Rev. 2013; 29(5):347-56. doi: 10.1002/dmrr.2403 PMID: 23463735
    • (2013) Diabetes Metab Res Rev. , vol.29 , Issue.5 , pp. 347-356
    • Raskin, P.1
  • 19
    • 84894358027 scopus 로고    scopus 로고
    • SGLT2 inhibitors enter crowded diabetes space
    • PMID: 23752410
    • Bouchie A. SGLT2 inhibitors enter crowded diabetes space. Nat Biotechnol. 2013; 31(6):469-70. doi: 10.1038/nbt0613-469 PMID: 23752410
    • (2013) Nat Biotechnol. , vol.31 , Issue.6 , pp. 469-470
    • Bouchie, A.1
  • 20
    • 84869998632 scopus 로고    scopus 로고
    • Dapagliflozin: A review of its use in type 2 diabetes mellitus
    • PMID: 23170914
    • Plosker GL. Dapagliflozin: a review of its use in type 2 diabetes mellitus. Drugs. 2012; 72(17):2289-312. doi: 10.2165/11209910-000000000-00000 PMID: 23170914
    • (2012) Drugs. , vol.72 , Issue.17 , pp. 2289-2312
    • Plosker, G.L.1
  • 21
    • 84891865819 scopus 로고    scopus 로고
    • Characterization of renal glucose reabsorption in response to dapagliflozin in healthy subjects and subjects with type 2 diabetes
    • PMID: 23735727
    • DeFronzo RA, Hompesch M, Kasichayanula S., Liu X, Hong Y, Pfister M., et al. Characterization of renal glucose reabsorption in response to dapagliflozin in healthy subjects and subjects with type 2 diabetes. Diabetes Care. 2013; 36(10):3169-76. doi: 10.2337/dc13-0387 PMID: 23735727
    • (2013) Diabetes Care. , vol.36 , Issue.10 , pp. 3169-3176
    • DeFronzo, R.A.1    Hompesch, M.2    Kasichayanula, S.3    Liu, X.4    Hong, Y.5    Pfister, M.6
  • 22
    • 84969915634 scopus 로고    scopus 로고
    • Efficacy and safety of sodium-glucose cotransporter 2 inhibitors in type 2 diabetes mellitus: Systematic review and network meta-analysis
    • Apr 5. [Epub ahead of print]
    • Zaccardi F, Webb DR, Htike Z.Z., Youssef D., Khunti K, Davies MJ. Efficacy and safety of sodium-glucose cotransporter 2 inhibitors in type 2 diabetes mellitus: Systematic review and network meta-analysis. Diabetes Obes Metab. 2016 Apr 5. [Epub ahead of print]
    • (2016) Diabetes Obes Metab.
    • Zaccardi, F.1    Webb, D.R.2    Htike, Z.Z.3    Youssef, D.4    Khunti, K.5    Davies, M.J.6
  • 23
    • 52649083832 scopus 로고    scopus 로고
    • Remogliflozin etabo-nate, in a novel category of selective low-affinity sodium glucose cotransporter (SGLT2) inhibitors, exhibits antidiabetic efficacy in rodent models
    • PMID: 18583547
    • Fujimori Y, Katsuno K, Nakashima I., Ishikawa-Takemura Y, Fujikura H, Isaji M. Remogliflozin etabo-nate, in a novel category of selective low-affinity sodium glucose cotransporter (SGLT2) inhibitors, exhibits antidiabetic efficacy in rodent models. J Pharmacol Exp Ther. 2008; 327(1):268-76. doi: 1124/jpet.108.140210 PMID: 18583547
    • (2008) J Pharmacol Exp Ther. , vol.327 , Issue.1 , pp. 268-276
    • Fujimori, Y.1    Katsuno, K.2    Nakashima, I.3    Ishikawa-Takemura, Y.4    Fujikura, H.5    Isaji, M.6
  • 24
    • 77957254503 scopus 로고    scopus 로고
    • The novel sodium glucose transporter 2 inhibitor dapagliflozin sustains pancreatic function and preserves islet morphology in obese, diabetic rats
    • PMID: 20880347
    • Macdonald FR, Peel JE, Jones H.B., Mayers RM, Westgate L, Whaley JM, et al The novel sodium glucose transporter 2 inhibitor dapagliflozin sustains pancreatic function and preserves islet morphology in obese, diabetic rats. Diabetes Obes Metab. 2010; 12(11):1004-12. doi: 10.1111/j.1463-1326.2010.01291.x PMID: 20880347
    • (2010) Diabetes Obes Metab. , vol.12 , Issue.11 , pp. 1004-1012
    • Macdonald, F.R.1    Peel, J.E.2    Jones, H.B.3    Mayers, R.M.4    Westgate, L.5    Whaley, J.M.6
  • 25
    • 84866540801 scopus 로고    scopus 로고
    • Effects of combining linagliptin treatment with BI-38335, a novel SGLT2 inhibitor, on pancreatic islet function and inflammation in db/db mice
    • PMID: 22804249
    • Chen L, Klein T, Leung PS Effects of combining linagliptin treatment with BI-38335, a novel SGLT2 inhibitor, on pancreatic islet function and inflammation in db/db mice. Curr Mol Med. 2012; 12(8):995-1004. PMID: 22804249
    • (2012) Curr Mol Med. , vol.12 , Issue.8 , pp. 995-1004
    • Chen, L.1    Klein, T.2    Leung, P.S.3
  • 26
    • 2442563673 scopus 로고    scopus 로고
    • Comparison of voglibose and nateglinide for their acute effects on insulin secretion and free fatty acid levels in OLETF rat portal blood after sucrose loading
    • PMID: 15034195
    • Mori Y, Kitahara Y, Miura K., Tajima N. Comparison of voglibose and nateglinide for their acute effects on insulin secretion and free fatty acid levels in OLETF rat portal blood after sucrose loading. Endocrine. 2004; 23(1):39-43. doi: 10.1385/ENDO:23:1:39 PMID: 15034195
    • (2004) Endocrine. , vol.23 , Issue.1 , pp. 39-43
    • Mori, Y.1    Kitahara, Y.2    Miura, K.3    Tajima, N.4
  • 27
    • 0029122656 scopus 로고
    • An alpha-glucosidase inhibitor, AO-128, retards carbohydrate absorption in rats and humans
    • PMID: 7587923
    • Goto Y, Yamada K, Ohyama T., Matsuo T, Odaka H, Ikeda H. An alpha-glucosidase inhibitor, AO-128, retards carbohydrate absorption in rats and humans. Diabetes Res Clin Pract. 1995; 28(2):81-7. PMID: 7587923
    • (1995) Diabetes Res Clin Pract. , vol.28 , Issue.2 , pp. 81-87
    • Goto, Y.1    Yamada, K.2    Ohyama, T.3    Matsuo, T.4    Odaka, H.5    Ikeda, H.6
  • 28
    • 84955602380 scopus 로고    scopus 로고
    • An atherogenic paigen-diet aggravates nephropathy in type 2 diabetic OLETF rats
    • PMID: 26606054
    • Nozako M, Koyama T, Nagano C., Sato M, Matsumoto S, Mitani K., et al. An Atherogenic Paigen-Diet Aggravates Nephropathy in Type 2 Diabetic OLETF Rats. PLOS ONE. 2015; 10(11):e0143979. doi: 10.1371/journal.pone.0143979 PMID: 26606054
    • (2015) PLOS ONE , vol.10 , Issue.11
    • Nozako, M.1    Koyama, T.2    Nagano, C.3    Sato, M.4    Matsumoto, S.5    Mitani, K.6
  • 29
    • 0026722931 scopus 로고
    • Spontaneous long-term hyperglycemic rat with diabetic complications. Otsuka long-evans tokushima fatty (OLETF) strain
    • PMID: 1397718
    • Kawano K, Hirashima T, Mori S., Saitoh Y, Kurosumi M, Natori T. Spontaneous long-term hyperglycemic rat with diabetic complications. Otsuka Long-Evans Tokushima Fatty (OLETF) strain. Diabetes. 1992; 41:1422-8. PMID: 1397718
    • (1992) Diabetes. , vol.41 , pp. 1422-1428
    • Kawano, K.1    Hirashima, T.2    Mori, S.3    Saitoh, Y.4    Kurosumi, M.5    Natori, T.6
  • 30
    • 33745313224 scopus 로고    scopus 로고
    • Accelerated diabetic nephropathy in mice lacking the peroxisome proliferator-activated receptor alpha
    • PMID: 16567507
    • Park CW, Kim HW, Ko S.H., Chung HW, Lim SW, Yang CW, et al Accelerated diabetic nephropathy in mice lacking the peroxisome proliferator-activated receptor alpha. Diabetes. 2006; 55(4):885-93. PMID: 16567507
    • (2006) Diabetes. , vol.55 , Issue.4 , pp. 885-893
    • Park, C.W.1    Kim, H.W.2    Ko, S.H.3    Chung, H.W.4    Lim, S.W.5    Yang, C.W.6
  • 31
    • 0000351855 scopus 로고
    • Practical methods for biological morphometry
    • London: Academic Press
    • Weibel ER. Practical methods for biological morphometry. Stereological Methods. London: Academic Press, 1979; 44-45
    • (1979) Stereological Methods , pp. 44-45
    • Weibel, E.R.1
  • 32
    • 33746018655 scopus 로고    scopus 로고
    • Orchiectomy attenuates post-ischemic oxidative stress and ischemia/reperfusion injury in mice. A role for manganese superoxide dismutase
    • PMID: 16682413
    • Kim J, Kil IS, Seok Y.M., Yang ES, Kim DK, Lim DG, et al Orchiectomy attenuates post-ischemic oxidative stress and ischemia/reperfusion injury in mice. A role for manganese superoxide dismutase. J Biol Chem. 2006; 281(29):20349-56. doi: 10.1074/jbc.M512740200 PMID: 16682413
    • (2006) J Biol Chem. , vol.281 , Issue.29 , pp. 20349-20356
    • Kim, J.1    Kil, I.S.2    Seok, Y.M.3    Yang, E.S.4    Kim, D.K.5    Lim, D.G.6
  • 33
    • 23044445962 scopus 로고    scopus 로고
    • Multifunctionality of PAI-1 in fibrogenesis: Evidence from obstructive nephropathy in PAI-1-overexpressing mice
    • PMID: 15882265
    • Matsuo S, López-Guisa JM, Cai X, Okamura DM, Alpers CE, Bumgarner RE, et al. Multifunctionality of PAI-1 in fibrogenesis: evidence from obstructive nephropathy in PAI-1-overexpressing mice. Kidney Int. 2005; 67(6):2221-38. doi: 10.1111/j.1523-1755.2005.00327.x PMID: 15882265
    • (2005) Kidney Int. , vol.67 , Issue.6 , pp. 2221-2238
    • Matsuo, S.1    López-Guisa, J.M.2    Cai, X.3    Okamura, D.M.4    Alpers, C.E.5    Bumgarner, R.E.6
  • 34
    • 0032892948 scopus 로고    scopus 로고
    • Angiotensin II: A pivotal factor in the progression of renal diseases
    • Wolf G. Angiotensin II: a pivotal factor in the progression of renal diseases. Nephrol Dial Transplant. 1999; 14 Suppl 1:42-4.
    • (1999) Nephrol Dial Transplant. , vol.14 , pp. 42-44
    • Wolf, G.1
  • 35
    • 59049099281 scopus 로고    scopus 로고
    • The importance of the intrarenal renin-angiotensin system
    • PMID: 19065132
    • Velez JC. The importance of the intrarenal renin-angiotensin system. Nat Clin Pract Nephrol. 2009; 5 (2):89-100. doi: 10.1038/ncpneph1015 PMID: 19065132
    • (2009) Nat Clin Pract Nephrol. , vol.5 , Issue.2 , pp. 89-100
    • Velez, J.C.1
  • 36
    • 84956926963 scopus 로고    scopus 로고
    • Reactive oxygen species and nuclear factor erythroid 2-related factor 2 activation in diabetic nephropathy: A hidden target
    • Abdo S, Zhang SL, Chan JS Reactive Oxygen Species and Nuclear Factor Erythroid 2-Related Factor 2 Activation in Diabetic Nephropathy: A Hidden Target. J Diabetes Metab. 2015; 6(6).
    • (2015) J Diabetes Metab. , vol.6 , Issue.6
    • Abdo, S.1    Zhang, S.L.2    Chan, J.S.3
  • 38
    • 0032835393 scopus 로고    scopus 로고
    • Role of angiotensin II in glucose-induced inhibition of mesan-gial matrix degradation
    • PMID: 10512375
    • Singh R, Alavi N, Singh A.K., Leehey DJ. Role of angiotensin II in glucose-induced inhibition of mesan-gial matrix degradation. Diabetes. 1999; 48(10):2066-73 PMID: 10512375
    • (1999) Diabetes. , vol.48 , Issue.10 , pp. 2066-2073
    • Singh, R.1    Alavi, N.2    Singh, A.K.3    Leehey, D.J.4
  • 39
    • 0034522676 scopus 로고    scopus 로고
    • High levels of glucose stimulate angio-tensinogen gene expression via the P38 mitogen-activated protein kinase pathway in rat kidney proximal tubular cells
    • PMID: 11108278
    • Zhang SL, Tang SS, Chen X, Filep J.G., Ingelfinger JR, Chan JS. High levels of glucose stimulate angio-tensinogen gene expression via the P38 mitogen-activated protein kinase pathway in rat kidney proximal tubular cells. Endocrinology. 2000; 141(12):4637-46. doi: 10.1210/endo.141.12.7844 PMID: 11108278
    • (2000) Endocrinology , vol.141 , Issue.12 , pp. 4637-4646
    • Zhang, S.L.1    Tang, S.S.2    Chen, X.3    Filep, J.G.4    Ingelfinger, J.R.5    Chan, J.S.6
  • 40
    • 0141785482 scopus 로고    scopus 로고
    • High glucose stimulates angio-tensinogen gene expression and cell hypertrophy via activation of the hexosamine biosynthesis pathway in rat kidney proximal tubular cells
    • PMID: 12960040
    • Hsieh TJ, Fustier P, Zhang S.L., Filep JG, Tang SS, Ingelfinger JR, et al High glucose stimulates angio-tensinogen gene expression and cell hypertrophy via activation of the hexosamine biosynthesis pathway in rat kidney proximal tubular cells. Endocrinology. 2003; 144(10):4338-49 doi: 10.1210/en.2003-0220 PMID: 12960040
    • (2003) Endocrinology , vol.144 , Issue.10 , pp. 4338-4349
    • Hsieh, T.J.1    Fustier, P.2    Zhang, S.L.3    Filep, J.G.4    Tang, S.S.5    Ingelfinger, J.R.6
  • 41
    • 0029767864 scopus 로고    scopus 로고
    • Phosphorylation of cAMP responsive element binding protein after treatment of mesangial cells with high glucose plus TGF beta or PMA
    • PMID: 8872954
    • Kreisberg JI, Radnik RA, Kreisberg SH Phosphorylation of cAMP responsive element binding protein after treatment of mesangial cells with high glucose plus TGF beta or PMA. Kidney Int. 1996; 50 (3):805-10. PMID: 8872954
    • (1996) Kidney Int. , vol.50 , Issue.3 , pp. 805-810
    • Kreisberg, J.I.1    Radnik, R.A.2    Kreisberg, S.H.3
  • 42
    • 0032007563 scopus 로고    scopus 로고
    • Identification of a novel mouse hepatic 52 kDa protein that interacts with the cAMP response element of the rat angiotensinogen gene
    • Wu J, Jiang Q, Chen X., Wu XH, Chan JS. Identification of a novel mouse hepatic 52 kDa protein that interacts with the cAMP response element of the rat angiotensinogen gene. Biochem J. 1998; 329(Pt 3):623-9.
    • (1998) Biochem J. , vol.329 , pp. 623-629
    • Wu, J.1    Jiang, Q.2    Chen, X.3    Wu, X.H.4    Chan, J.S.5
  • 43
    • 77956118841 scopus 로고    scopus 로고
    • High glucose upregulates upstream stimulatory factor 2 in human renal proximal tubular cells through angiotensin II-dependent activation of CREB
    • PMID: 20814220
    • Visavadiya NP, Li Y, Wang S. High glucose upregulates upstream stimulatory factor 2 in human renal proximal tubular cells through angiotensin II-dependent activation of CREB. Nephron Exp Nephrol. 2011; 117(3):e62-70. doi: 10.1159/000320594 PMID: 20814220
    • (2011) Nephron Exp Nephrol. , vol.117 , Issue.3 , pp. e62-e70
    • Visavadiya, N.P.1    Li, Y.2    Wang, S.3
  • 44
    • 84860783536 scopus 로고    scopus 로고
    • Dapagliflozin: A novel sodium-glucose cotransporter type 2 inhibitor for the treatment of type 2 diabetes mellitus
    • PMID: 22392830
    • Shah NK, Deeb WE, Choksi R, Epstein BJ Dapagliflozin: a novel sodium-glucose cotransporter type 2 inhibitor for the treatment of type 2 diabetes mellitus. Pharmacotherapy. 2012; 32(1):80-94. doi: 10. 1002/PHAR.1010 PMID: 22392830
    • (2012) Pharmacotherapy. , vol.32 , Issue.1 , pp. 80-94
    • Shah, N.K.1    Deeb, W.E.2    Choksi, R.3    Epstein, B.J.4
  • 45
    • 84871015248 scopus 로고    scopus 로고
    • Dapagliflozin: A review on efficacy, clinical effectiveness and safety
    • PMID: 23127205
    • Paisley AN, Yadav R, Younis N., Rao-Balakrishna P, Soran H. Dapagliflozin: a review on efficacy, clinical effectiveness and safety. Expert Opin Investig Drugs. 2013; 22(1):131-40. doi: 10.1517/13543784.2013.740009 PMID: 23127205
    • (2013) Expert Opin Investig Drugs. , vol.22 , Issue.1 , pp. 131-140
    • Paisley, A.N.1    Yadav, R.2    Younis, N.3    Rao-Balakrishna, P.4    Soran, H.5
  • 46
    • 84871804484 scopus 로고    scopus 로고
    • Sodium glucose cotransporter 2 and the diabetic kidney
    • PMID: 23042029
    • Komala MG, Panchapakesan U, Pollock C., Mather A. Sodium glucose cotransporter 2 and the diabetic kidney. Curr Opin Nephrol Hypertens. 2013; 22(1):113-9. doi: 10.1097/MNH.0b013e32835a17ae PMID: 23042029
    • (2013) Curr Opin Nephrol Hypertens. , vol.22 , Issue.1 , pp. 113-119
    • Komala, M.G.1    Panchapakesan, U.2    Pollock, C.3    Mather, A.4
  • 47
    • 84903528312 scopus 로고    scopus 로고
    • Long-term treatment with the sodium glucose cotransporter 2 inhibitor, dapagliflozin, ameliorates glucose homeostasis and diabetic nephropathy in db/db mice
    • 9 PMID: 24960177
    • Terami N, Ogawa D, Tachibana H., Hatanaka T, Wada J, Nakatsuka A., et al. Long-term treatment with the sodium glucose cotransporter 2 inhibitor, dapagliflozin, ameliorates glucose homeostasis and diabetic nephropathy in db/db mice. PLOS ONE. 2014; 24; 9(6):e100777. doi: 10.1371/journal.pone.0100777 PMID: 24960177
    • (2014) PLOS ONE , vol.24 , Issue.6
    • Terami, N.1    Ogawa, D.2    Tachibana, H.3    Hatanaka, T.4    Wada, J.5    Nakatsuka, A.6
  • 48
    • 84884554260 scopus 로고    scopus 로고
    • Tofogliflozin, a novel sodium-glucose co-transporter 2 inhibitor, improves renal and pancreatic function in db/db mice
    • PMID: 23751087
    • Nagata T, Fukuzawa T, Takeda M., Fukazawa M, Mori T, Nihei T et al. Tofogliflozin, a novel sodium-glucose co-transporter 2 inhibitor, improves renal and pancreatic function in db/db mice. Br J Pharmacol 2013; 170:519-31. doi: 10.1111/bph.12269 PMID: 23751087
    • (2013) Br J Pharmacol , vol.170 , pp. 519-531
    • Nagata, T.1    Fukuzawa, T.2    Takeda, M.3    Fukazawa, M.4    Mori, T.5    Nihei, T.6
  • 49
    • 84885476895 scopus 로고    scopus 로고
    • Effects of SGLT2 selective inhibitor ipragliflozin on hyperglycemia, hyperlipidemia, hepatic steatosis, oxidative stress, inflammation, and obesity in type 2 diabetic mice
    • PMID: 23707905
    • Tahara A, Kurosaki E, Yokono M., Yamajuku D, Kihara R, Hayashizaki Y., et al. Effects of SGLT2 selective inhibitor ipragliflozin on hyperglycemia, hyperlipidemia, hepatic steatosis, oxidative stress, inflammation, and obesity in type 2 diabetic mice. Eur J Pharmacol. 2013; 715(1-3):246-55 doi: 10.1016/j.ejphar.2013.05.014 PMID: 23707905
    • (2013) Eur J Pharmacol. , vol.715 , Issue.1-3 , pp. 246-255
    • Tahara, A.1    Kurosaki, E.2    Yokono, M.3    Yamajuku, D.4    Kihara, R.5    Hayashizaki, Y.6


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