메뉴 건너뛰기




Volumn 68, Issue 6, 2016, Pages 1355-1364

Impact of Empagliflozin on Blood Pressure in Patients with Type 2 Diabetes Mellitus and Hypertension by Background Antihypertensive Medication

Author keywords

antihypertensive; blood pressure; diuretic; empagliflozin; hypertension; SGLT2 inhibitor; type 2 diabetes mellitus

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; EMPAGLIFLOZIN; PLACEBO; ANTIDIABETIC AGENT; ANTIHYPERTENSIVE AGENT; BENZHYDRYL DERIVATIVE; GLUCOSE BLOOD LEVEL; GLUCOSIDE;

EID: 84994853573     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.116.07703     Document Type: Article
Times cited : (99)

References (28)
  • 1
    • 84901467782 scopus 로고    scopus 로고
    • Importance of cardiovascular disease risk management in patients with type 2 diabetes mellitus
    • Lorber D. Importance of cardiovascular disease risk management in patients with type 2 diabetes mellitus. Diabetes Metab Syndr Obes. 2014;7:169-183. doi: 10.2147/DMSO.S61438.
    • (2014) Diabetes Metab Syndr Obes. , vol.7 , pp. 169-183
    • Lorber, D.1
  • 2
    • 84884547666 scopus 로고    scopus 로고
    • Prevalence of hypertension and obesity in patients with type 2 diabetes mellitus in observational studies: A systematic literature review
    • Colosia AD, Palencia R, Khan S. Prevalence of hypertension and obesity in patients with type 2 diabetes mellitus in observational studies: a systematic literature review. Diabetes Metab Syndr Obes. 2013;6:327-338. doi: 10.2147/DMSO.S51325.
    • (2013) Diabetes Metab Syndr Obes. , vol.6 , pp. 327-338
    • Colosia, A.D.1    Palencia, R.2    Khan, S.3
  • 3
    • 65249111029 scopus 로고    scopus 로고
    • Lowering blood pressure reduces renal events in type 2 diabetes
    • de Galan BE, Perkovic V, Ninomiya T, et al.; ADVANCE Collaborative Group. Lowering blood pressure reduces renal events in type 2 diabetes. J Am Soc Nephrol. 2009;20:883-892. doi: 10.1681/ASN.2008070667.
    • (2009) J Am Soc Nephrol. , vol.20 , pp. 883-892
    • De Galan, B.E.1    Perkovic, V.2    Ninomiya, T.3
  • 4
    • 84880930315 scopus 로고    scopus 로고
    • 2013 ESH/ESC guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)
    • Mancia G, Fagard R, Narkiewicz K, et al. 2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J. 2013;34:2159-2219. doi: 10.1093/eurheartj/eht151.
    • (2013) Eur Heart J. , vol.34 , pp. 2159-2219
    • Mancia, G.1    Fagard, R.2    Narkiewicz, K.3
  • 5
    • 84855539606 scopus 로고    scopus 로고
    • American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for developing a diabetes mellitus comprehensive care plan
    • Handelsman Y, Mechanick JI, Blonde L, et al.; AACE Task Force for Developing Diabetes Comprehensive Care Plan. American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for developing a diabetes mellitus comprehensive care plan. Endocr Pract. 2011;17(suppl 2):1-53.
    • (2011) Endocr Pract. , vol.17 , pp. 1-53
    • AACE Task Force for Developing Diabetes Comprehensive Care Plan1    Handelsman, Y.2    Mechanick, J.I.3    Blonde, L.4
  • 7
    • 84892649479 scopus 로고    scopus 로고
    • Standards of medical care in diabetes - 2014
    • American Diabetes Association. Standards of medical care in diabetes - 2014. Diabetes Care. 2014;37(suppl 1):S14-S80. doi: 10.2337/dc14-S014.
    • (2014) Diabetes Care. , vol.37 , pp. S14-S80
    • American Diabetes Association1
  • 8
    • 84893549987 scopus 로고    scopus 로고
    • 2014 evidence-based guideline for the management of high blood pressure in adults: Report from the panel members appointed to the Eighth Joint National Committee (JNC 8)
    • James PA, Oparil S, Carter BL, et al. 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA. 2014;311:507-520. doi: 10.1001/jama.2013.284427.
    • (2014) JAMA , vol.311 , pp. 507-520
    • James, P.A.1    Oparil, S.2    Carter, B.L.3
  • 9
    • 84882254968 scopus 로고    scopus 로고
    • The prevalence of meeting A1C, blood pressure, and LDL goals among people with diabetes, 1988-2010
    • Stark Casagrande S, Fradkin JE, Saydah SH, Rust KF, Cowie CC. The prevalence of meeting A1C, blood pressure, and LDL goals among people with diabetes, 1988-2010. Diabetes Care. 2013;36:2271-2279. doi: 10.2337/dc12-2258.
    • (2013) Diabetes Care. , vol.36 , pp. 2271-2279
    • Stark Casagrande, S.1    Fradkin, J.E.2    Saydah, S.H.3    Rust, K.F.4    Cowie, C.C.5
  • 11
    • 0036668188 scopus 로고    scopus 로고
    • Systolic and diastolic blood pressure control in antihypertensive drug trials
    • Mancia G, Grassi G. Systolic and diastolic blood pressure control in antihypertensive drug trials. J Hypertens. 2002;20:1461-1464.
    • (2002) J Hypertens. , vol.20 , pp. 1461-1464
    • Mancia, G.1    Grassi, G.2
  • 12
    • 80054959783 scopus 로고    scopus 로고
    • Blood pressure targets recommended by guidelines and incidence of cardiovascular and renal events in the Ongoing Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial (ONTARGET)
    • Mancia G, Schumacher H, Redon J, Verdecchia P, Schmieder R, Jennings G, Yusoff K, Ryden L, Liu GL, Teo K, Sleight P, Yusuf S. Blood pressure targets recommended by guidelines and incidence of cardiovascular and renal events in the Ongoing Telmisartan Alone and in Combination With Ramipril Global Endpoint Trial (ONTARGET). Circulation. 2011;124:1727-1736. doi: 10.1161/CIRCULATIONAHA.110.008870.
    • (2011) Circulation. , vol.124 , pp. 1727-1736
    • Mancia, G.1    Schumacher, H.2    Redon, J.3    Verdecchia, P.4    Schmieder, R.5    Jennings, G.6    Yusoff, K.7    Ryden, L.8    Liu, G.L.9    Teo, K.10    Sleight, P.11    Yusuf, S.12
  • 13
    • 84878947970 scopus 로고    scopus 로고
    • Safety, tolerability, pharmacokinetics and pharmacodynamics following 4 weeks' treatment with empagliflozin once daily in patients with type 2 diabetes
    • Heise T, Seewaldt-Becker E, Macha S, Hantel S, Pinnetti S, Seman L, Woerle HJ. Safety, tolerability, pharmacokinetics and pharmacodynamics following 4 weeks' treatment with empagliflozin once daily in patients with type 2 diabetes. Diabetes Obes Metab. 2013;15:613-621. doi: 10.1111/dom.12073.
    • (2013) Diabetes Obes Metab. , vol.15 , pp. 613-621
    • Heise, T.1    Seewaldt-Becker, E.2    Macha, S.3    Hantel, S.4    Pinnetti, S.5    Seman, L.6    Woerle, H.J.7
  • 14
    • 84899961819 scopus 로고    scopus 로고
    • Efficacy and safety of empagliflozin added to existing antidiabetes treatment in patients with type 2 diabetes and chronic kidney disease: A randomised, double-blind, placebo-controlled trial
    • Barnett AH, Mithal A, Manassie J, Jones R, Rattunde H, Woerle HJ, Broedl UC; EMPA-REG RENAL trial investigators. Efficacy and safety of empagliflozin added to existing antidiabetes treatment in patients with type 2 diabetes and chronic kidney disease: a randomised, double-blind, placebo-controlled trial. Lancet Diabetes Endocrinol. 2014;2:369-384. doi: 10.1016/S2213-8587(13)70208-0.
    • (2014) Lancet Diabetes Endocrinol. , vol.2 , pp. 369-384
    • Barnett, A.H.1    Mithal, A.2    Manassie, J.3    Jones, R.4    Rattunde, H.5    Woerle, H.J.6    Broedl, U.C.7
  • 15
    • 84885952950 scopus 로고    scopus 로고
    • Empagliflozin as add-on to metformin plus sulfonylurea in patients with type 2 diabetes: A 24-week, randomized, double-blind, placebo-controlled trial
    • Häring HU, Merker L, Seewaldt-Becker E, Weimer M, Meinicke T, Woerle HJ, Broedl UC; EMPA-REG METSU Trial Investigators. Empagliflozin as add-on to metformin plus sulfonylurea in patients with type 2 diabetes: a 24-week, randomized, double-blind, placebo-controlled trial. Diabetes Care. 2013;36:3396-3404. doi: 10.2337/dc12-2673.
    • (2013) Diabetes Care. , vol.36 , pp. 3396-3404
    • Häring, H.U.1    Merker, L.2    Seewaldt-Becker, E.3    Weimer, M.4    Meinicke, T.5    Woerle, H.J.6    Broedl, U.C.7
  • 16
    • 84901455931 scopus 로고    scopus 로고
    • Empagliflozin as add-on to metformin in patients with type 2 diabetes: A 24-week, randomized, double-blind, placebo-controlled trial
    • Häring HU, Merker L, Seewaldt-Becker E, Weimer M, Meinicke T, Broedl UC, Woerle HJ; EMPA-REG MET Trial Investigators. Empagliflozin as add-on to metformin in patients with type 2 diabetes: a 24-week, randomized, double-blind, placebo-controlled trial. Diabetes Care. 2014;37:1650-1659. doi: 10.2337/dc13-2105.
    • (2014) Diabetes Care. , vol.37 , pp. 1650-1659
    • Häring, H.U.1    Merker, L.2    Seewaldt-Becker, E.3    Weimer, M.4    Meinicke, T.5    Broedl, U.C.6    Woerle, H.J.7
  • 17
    • 84892477577 scopus 로고    scopus 로고
    • Empagliflozin improves glycaemic and weight control as add-on therapy to pioglitazone or pioglitazone plus metformin in patients with type 2 diabetes: A 24-week, randomized, placebo-controlled trial
    • Kovacs CS, Seshiah V, Swallow R, Jones R, Rattunde H, Woerle HJ, Broedl UC; EMPA-REG PIO™ trial investigators. Empagliflozin improves glycaemic and weight control as add-on therapy to pioglitazone or pioglitazone plus metformin in patients with type 2 diabetes: a 24-week, randomized, placebo-controlled trial. Diabetes Obes Metab. 2014;16:147-158. doi: 10.1111/dom.12188.
    • (2014) Diabetes Obes Metab. , vol.16 , pp. 147-158
    • Kovacs, C.S.1    Seshiah, V.2    Swallow, R.3    Jones, R.4    Rattunde, H.5    Woerle, H.J.6    Broedl, U.C.7
  • 18
    • 84885954870 scopus 로고    scopus 로고
    • Empagliflozin monotherapy with sitagliptin as an active comparator in patients with type 2 diabetes: A randomised, double-blind, placebo-controlled, phase 3 trial
    • Roden M, Weng J, Eilbracht J, Delafont B, Kim G, Woerle HJ, Broedl UC; EMPA-REG MONO trial investigators. Empagliflozin monotherapy with sitagliptin as an active comparator in patients with type 2 diabetes: a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Diabetes Endocrinol. 2013;1:208-219. doi: 10.1016/S2213-8587(13)70084-6.
    • (2013) Lancet Diabetes Endocrinol. , vol.1 , pp. 208-219
    • Roden, M.1    Weng, J.2    Eilbracht, J.3    Delafont, B.4    Kim, G.5    Woerle, H.J.6    Broedl, U.C.7
  • 20
    • 84928196614 scopus 로고    scopus 로고
    • Empagliflozin reduces blood pressure in patients with type 2 diabetes and hypertension
    • Tikkanen I, Narko K, Zeller C, Green A, Salsali A, Broedl UC, Woerle HJ; EMPA-REG BP Investigators. Empagliflozin reduces blood pressure in patients with type 2 diabetes and hypertension. Diabetes Care. 2015;38:420-428. doi: 10.2337/dc14-1096.
    • (2015) Diabetes Care. , vol.38 , pp. 420-428
    • Tikkanen, I.1    Narko, K.2    Zeller, C.3    Green, A.4    Salsali, A.5    Broedl, U.C.6    Woerle, H.J.7
  • 21
    • 84958125420 scopus 로고    scopus 로고
    • Effects of dapagliflozin on blood pressure in hypertensive diabetic patients on renin-angiotensin system blockade
    • Weber MA, Mansfield TA, Alessi F, Iqbal N, Parikh S, Ptaszynska A. Effects of dapagliflozin on blood pressure in hypertensive diabetic patients on renin-angiotensin system blockade. Blood Press. 2016;25:93-103. doi: 10.3109/08037051.2015.1116258.
    • (2016) Blood Press. , vol.25 , pp. 93-103
    • Weber, M.A.1    Mansfield, T.A.2    Alessi, F.3    Iqbal, N.4    Parikh, S.5    Ptaszynska, A.6
  • 23
    • 84945455839 scopus 로고    scopus 로고
    • Effects of empagliflozin on blood pressure and markers of arterial stiffness and vascular resistance in patients with type 2 diabetes
    • Chilton R, Tikkanen I, Cannon CP, Crowe S, Woerle HJ, Broedl UC, Johansen OE. Effects of empagliflozin on blood pressure and markers of arterial stiffness and vascular resistance in patients with type 2 diabetes. Diabetes Obes Metab. 2015;17:1180-1193. doi: 10.1111/dom.12572.
    • (2015) Diabetes Obes Metab. , vol.17 , pp. 1180-1193
    • Chilton, R.1    Tikkanen, I.2    Cannon, C.P.3    Crowe, S.4    Woerle, H.J.5    Broedl, U.C.6    Johansen, O.E.7
  • 24
    • 84930157148 scopus 로고    scopus 로고
    • Clinical value of ambulatory blood pressure: Evidence and limits
    • Mancia G, Verdecchia P. Clinical value of ambulatory blood pressure: evidence and limits. Circ Res. 2015;116:1034-1045. doi: 10.1161/CIRCRESAHA.116.303755.
    • (2015) Circ Res. , vol.116 , pp. 1034-1045
    • Mancia, G.1    Verdecchia, P.2
  • 25
    • 85027487177 scopus 로고    scopus 로고
    • Contrasting influences of renal function on blood pressure and HbA1c reductions with empagliflozin in patients with type 2 diabetes and hypertension
    • Cherney D, Cooper M, Tikkanen I, Crowe S, Johansen OE, Lund SS, Woerle HJ4, Broedl UC, Hach T. Contrasting influences of renal function on blood pressure and HbA1c reductions with empagliflozin in patients with type 2 diabetes and hypertension. Circulation. 2014;130:A16709.
    • (2014) Circulation. , vol.130 , pp. A16709
    • Cherney, D.1    Cooper, M.2    Tikkanen, I.3    Crowe, S.4    Johansen, O.E.5    Lund, S.S.6    Woerle, H.J.7    Broedl, U.C.8    Hach, T.9
  • 26
    • 84923108094 scopus 로고    scopus 로고
    • SGLT2 inhibitors: Their potential reduction in blood pressure
    • Maliha G, Townsend RR. SGLT2 inhibitors: their potential reduction in blood pressure. J Am Soc Hypertens. 2015;9:48-53. doi: 10.1016/j. jash.2014.11.001.
    • (2015) J Am Soc Hypertens. , vol.9 , pp. 48-53
    • Maliha, G.1    Townsend, R.R.2
  • 28
    • 84957441669 scopus 로고    scopus 로고
    • Potential role of sodium glucose cotransporter 2 inhibitors in the treatment of hypertension
    • Tikkanen I, Chilton R, Johansen OE. Potential role of sodium glucose cotransporter 2 inhibitors in the treatment of hypertension. Curr Opin Nephrol Hypertens. 2016;25:81-86. doi: 10.1097/MNH.0000000000000199.
    • (2016) Curr Opin Nephrol Hypertens. , vol.25 , pp. 81-86
    • Tikkanen, I.1    Chilton, R.2    Johansen, O.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.