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Volumn 13, Issue 5, 2015, Pages

Scientific Opinion on the substantiation of a health claim related to coffee C21, a coffee standardised by its content of caffeoylquinic acids, trigonelline and N-methylpyridinium, and reduction of DNA damage by decreasing spontaneous DNA strand breaks pursuant to Article 13(5) of Regulation (EC) No 1924/2006
[No Author Info available]

Author keywords

C21; coffee; DNA damage; DNA strand break; health claims

Indexed keywords


EID: 85062069756     PISSN: None     EISSN: 18314732     Source Type: Journal    
DOI: 10.2903/j.efsa.2015.4099     Document Type: Article
Times cited : (2)

References (12)
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    • Coffee consumption protects human lymphocytes against oxidative and 3-amino-1-methyl-5H-pyrido[4,3-b]indole acetate (Trp-P-2) induced DNA-damage: results of an experimental study with human volunteers
    • Bichler J, Cavin C, Simic T, Chakraborty A, Ferk F, Hoelzl C, Schulte-Hermann R, Kundi M, Haidinger G, Angelis K and Knasmüller S, 2007. Coffee consumption protects human lymphocytes against oxidative and 3-amino-1-methyl-5H-pyrido[4,3-b]indole acetate (Trp-P-2) induced DNA-damage: results of an experimental study with human volunteers. Food and Chemical Toxicology, 45, 1428–1436.
    • (2007) Food and Chemical Toxicology , vol.45 , pp. 1428-1436
    • Bichler, J.1    Cavin, C.2    Simic, T.3    Chakraborty, A.4    Ferk, F.5    Hoelzl, C.6    Schulte-Hermann, R.7    Kundi, M.8    Haidinger, G.9    Angelis, K.10    Knasmüller, S.11
  • 6
    • 84928239194 scopus 로고    scopus 로고
    • Guidance on the scientific requirements for health claims related to antioxidants, oxidative damage and cardiovascular health
    • 2011
    • EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2011. Guidance on the scientific requirements for health claims related to antioxidants, oxidative damage and cardiovascular health. EFSA Journal 2011;9(12):2474, 13 pp. doi:10.2903/j.efsa.2011.2474.
    • (2011) EFSA Journal , vol.9 , Issue.12 , pp. 2474-2413
  • 8
    • 58949096676 scopus 로고    scopus 로고
    • Quantitative investigation of trigonelline, nicotinic acid, and nicotinamide in foods, urine, and plasma by means of LC-MS/MS and stable isotope dilution analysis
    • Lang R, Yagar EF, Eggers R and Hofmann T, 2008. Quantitative investigation of trigonelline, nicotinic acid, and nicotinamide in foods, urine, and plasma by means of LC-MS/MS and stable isotope dilution analysis. Journal of Agricultural and Food Chemistry, 56, 11114–11121.
    • (2008) Journal of Agricultural and Food Chemistry , vol.56 , pp. 11114-11121
    • Lang, R.1    Yagar, E.F.2    Eggers, R.3    Hofmann, T.4
  • 10
    • 77950339912 scopus 로고    scopus 로고
    • Degree of roasting is the main determinant of the effects of coffee on NF-kappaB and EpRE
    • Paur I, Balstad TR and Blomhoff R, 2010. Degree of roasting is the main determinant of the effects of coffee on NF-kappaB and EpRE. Free Radical Biology and Medicine, 48, 1218–1227.
    • (2010) Free Radical Biology and Medicine , vol.48 , pp. 1218-1227
    • Paur, I.1    Balstad, T.R.2    Blomhoff, R.3
  • 11
    • 27844535342 scopus 로고    scopus 로고
    • Coffee consumption induces GSTP in plasma and protects lymphocytes against (±)-anti-benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide induced DNA-damage: results of controlled human intervention trials
    • Steinkellner H, Hoelzl C, Uhl M, Cavin C, Haidinger G, Gsur A, Schmid R, Kundi M, Bichler J and Knasmüller S, 2005. Coffee consumption induces GSTP in plasma and protects lymphocytes against (±)-anti-benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide induced DNA-damage: results of controlled human intervention trials. Mutation Research, 591, 264–275.
    • (2005) Mutation Research , vol.591 , pp. 264-275
    • Steinkellner, H.1    Hoelzl, C.2    Uhl, M.3    Cavin, C.4    Haidinger, G.5    Gsur, A.6    Schmid, R.7    Kundi, M.8    Bichler, J.9    Knasmüller, S.10
  • 12
    • 84892172397 scopus 로고    scopus 로고
    • Coffee modulates transcription factor Nrf2 and highly increases the activity of antioxidant enzymes in rats
    • Vicente SJ, Ishimoto EY and Torres EA, 2014. Coffee modulates transcription factor Nrf2 and highly increases the activity of antioxidant enzymes in rats. Journal of Agricultural and Food Chemistry, 62, 116–122.
    • (2014) Journal of Agricultural and Food Chemistry , vol.62 , pp. 116-122
    • Vicente, S.J.1    Ishimoto, E.Y.2    Torres, E.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.