Instant coffee with high chlorogenic acid levels protects humans against oxidative damage of macromolecules

Molecular Nutrition and Food Research

Volumn 54, Issue 12, 2010, Pages 1722-1733

  Hoelzl, Christine ^a   Knasmüller, Siegfried ^a   Wagner, Karl Heinz ^b   Elbling, Leonilla ^a   Huber, Wolfgang ^a   Kager, Nina ^a   Ferk, Franziska ^a   Ehrlich, Veronika ^a   Nersesyan, Armen ^a   Neubauer, Oliver ^b   Desmarchelier, Aurélien ^c   Marin Kuan, Maricel ^c   Delatour, Thierry ^c   Verguet, Clotilde ^c   Bezençon, Claudine ^c   Besson, Amélie ^c   Grathwohl, Dominik ^c   Simic, Tatjana ^d   Kundi, Michael ^e   Schilter, Benoît ^c   Cavin, Christophe ^c   more..

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF VIENNA   (Austria)

^c NESTLÉ RESEARCH CENTER   (Switzerland)

^d UNIVERSITY OF BELGRADE   (Serbia)

^e MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Antioxidants; Chlorogenic acids; Instant coffee; Intervention trial

Indexed keywords

3 NITROTYROSINE; 3-NITROTYROSINE; 8 EPI PROSTAGLANDIN F2ALPHA; 8-EPI-PROSTAGLANDIN F2ALPHA; ANTIOXIDANT; CHLOROGENIC ACID; DRUG DERIVATIVE; MALONALDEHYDE; PROSTAGLANDIN F2 ALPHA; REACTIVE OXYGEN METABOLITE; TYROSINE;

ADULT; ARTICLE; CHEMISTRY; COFFEE; COMET ASSAY; DNA DAMAGE; FEMALE; HUMAN; INTERVENTION STUDY; LIPID PEROXIDATION; LYMPHOCYTE; MACROMOLECULE; MALE; METABOLISM; MIDDLE AGED; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; URINE;

ADULT; ANTIOXIDANTS; CHLOROGENIC ACID; COFFEE; COMET ASSAY; DINOPROST; DNA DAMAGE; FEMALE; HUMANS; INTERVENTION STUDIES; LIPID PEROXIDATION; LYMPHOCYTES; MACROMOLECULAR SUBSTANCES; MALE; MALONDIALDEHYDE; MIDDLE AGED; OXIDATION-REDUCTION; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; TYROSINE; YOUNG ADULT;

EID: 78449270685     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201000048     Document Type: Article

References (63)

1. Valko, M., Leibfritz, D., Moncol, J., Cronin, M. T., et al., Free radicals and antioxidants in normal physiological functions and human disease. Int. J. Biochem. Cell. Biol. 2007, 39, 44-84.
2. Ames, B. N., Shigenaga, M. K., Hagen, T. M., Oxidants, antioxidants, and the degenerative diseases of aging. Proc. Natl. Acad. Sci. USA 1993, 90, 7915-7922.
3. Hussain, S. P., Hofseth, L. J., Harris, C. C., Radical causes of cancer. Nat. Rev. Cancer 2003, 3, 276-285.
4. Knasmuller, S., Nersesyan, A., Misik, M., Gerner, C., et al., Use of conventional and -omics based methods for health claims of dietary antioxidants: a critical overview. Br. J. Nutr. 2008, 99, 3-52.
5. Bichler, J., Cavin, C., Simic, T., Chakraborty, A., et al., Coffee consumption protects human lymphocytes against oxidative and 3-amino-1-methyl-5H-pyrido[4, 3-b]indole acetate (Trp-P-2) induced DNA-damage: results of an experimental study with human volunteers. Food Chem. Toxicol. 2007, 45, 1428-1436.
6. Faustmann, G., Cavin, C., Nersesyan, A., Knasmüller, S., in: Knasmüller, S., DeMarini, D. M., Johnson, I. T., Gerhäuser, C. (Eds.), Chemoprevention of Cancer and DNA Damage by Dietary Factors, Wiley-VCH, Weinheim 2009, pp. 579-594.
7. Cavin, C., Marin-Kuan, M., Langouet, S., Bezencon, C., et al., Induction of Nrf2-mediated cellular defenses and alteration of phase I activities as mechanisms of chemoprotective effects of coffee in the liver. Food Chem. Toxicol. 2008, 46, 1239-1248.
8. Higgins, L. G., Cavin, C., Itoh, K., Yamamoto, M., Hayes, J. D., Induction of cancer chemopreventive enzymes by coffee is mediated by transcription factor Nrf2. Evidence that the coffee-specific diterpenes cafestol and kahweol confer protection against acrolein. Toxicol. Appl. Pharmacol. 2008, 226, 328-337.
9. Pellegrini, N., Serafini, M., Colombi, B., Del Rio, D., et al., Total antioxidant capacity of plant foods, beverages and oils consumed in Italy assessed by three different in vitro assays. J. Nutr. 2003, 133, 2812-2819.
10. Svilaas, A., Sakhi, A. K., Andersen, L. F., Svilaas, T., et al., Intakes of antioxidants in coffee, wine, and vegetables are correlated with plasma carotenoids in humans. J. Nutr. 2004, 134, 562-567.
11. Lindsay, J., Laurin, D., Verreault, R., Hebert, R., et al., Risk factors for Alzheimer's disease: a prospective analysis from the Canadian Study of Health and Aging. Am. J. Epidemiol. 2002, 156, 445-453.
12. Salazar-Martinez, E., Willett, W. C., Ascherio, A., Manson, J. E., et al., Coffee consumption and risk for type 2 diabetes mellitus. Ann. Intern. Med. 2004, 140, 1-8.
13. Higdon, J. V., Frei, B., Coffee and health: a review of recent human research. Crit. Rev. Food Sci. Nutr. 2006, 46, 101-123.
14. Moreira, D. P., Monteiro, M. C., Ribeiro-Alves, M., Donangelo, C. M., Trugo, L. C., Contribution of chlorogenic acids to the iron-reducing activity of coffee beverages. J. Agric. Food Chem. 2005, 53, 1399-1402.
15. Bonita, J. S., Mandarano, M., Shuta, D., Vinson, J., Coffee and cardiovascular disease: in vitro, cellular, animal, and human studies. Pharmacol. Res. 2007, 55, 187-198.
16. Yen, W. J., Wang, B. S., Chang, L. W., Duh, P. D., Antioxidant properties of roasted coffee residues. J. Agric. Food Chem. 2005, 53, 2658-2663.
17. Young, I. S., Oxidative stress and vascular disease: insights from isoprostane measurement. Clin. Chem. 2005, 51, 14-15.
18. Souza, J. M., Peluffo, G., Radi, R., Protein tyrosine nitration - functional alteration or just a biomarker? Free Radic. Biol. Med. 2008, 45, 357-366.
19. Hoelzl, C., Knasmuller, S., Misik, M., Collins, A., et al., Use of single cell gel electrophoresis assays for the detection of DNA-protective effects of dietary factors in humans: recent results and trends. Mutat. Res. 2009, 681, 68-79.
20. Neubauer, O., Reichhold, S., Nersesyan, A., Konig, D., Wagner, K. H., Exercise-induced DNA damage: is there a relationship with inflammatory responses? Exerc. Immunol. Rev. 2008, 14, 51-72.
21. Bekedam, E. K., Loots, M. J., Schols, H. A., Van Boekel, M. A., Smit, G., Roasting effects on formation mechanisms of coffee brew melanoidins. J. Agric. Food Chem. 2008, 56, 7138-7145.
22. Collins, A. R., Dobson, V. L., Dusinska, M., Kennedy, G., Stetina, R., The comet assay: what can it really tell us? Mutat. Res. 1997, 375, 183-193.
23. Collins, A. R., Duthie, S. J., Dobson, V. L., Direct enzymic detection of endogenous oxidative base damage in human lymphocyte DNA. Carcinogenesis 1993, 14, 1733-1735.
24. Collins, A., Dusinska, M., Franklin, M., Somorovska, M., et al., Comet assay in human biomonitoring studies: reliability, validation, and applications. Environ. Mol. Mutagen. 1997, 30, 139-146.
25. Collins, A. R., The comet assay for DNA damage and repair: principles, applications, and limitations. Mol. Biotechnol. 2004, 26, 249-261.
26. Collins, A. R., Oscoz, A. A., Brunborg, G., Gaivao, I. et al., The comet assay: topical issues. Mutagenesis 2008, 23, 143-151.
27. Lindl, T., Bauer, J., Zell- und Gewebekultur, Stuttgart, Jena, New York 1994.
28. Hartmann, A., Agurell, E., Beevers, C., Brendler-Schwaab, S., et al., Recommendations for conducting the in vivo alkaline Comet assay. 4th International Comet Assay Workshop. Mutagenesis 2003, 18, 45-51.
29. Singh, N. P., McCoy, M. T., Tice, R. R., Schneider, E. L., A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell. Res. 1988, 175, 184-191.
30. Richelle, M., Turini, M. E., Guidoux, R., Tavazzi, I., et al., Urinary isoprostane excretion is not confounded by the lipid content of the diet. FEBS Lett. 1999, 459, 259-262.
31. Ramel, A., Wagner, K. H., Elmadfa, I., Plasma antioxidants and lipid oxidation after submaximal resistance exercise in men. Eur. J. Nutr. 2004, 43, 2-6.
32. Delatour, T., Richoz, J., Vuichoud, J., Stadler, R. H., Artifactual nitration controlled measurement of protein-bound 3-nitro-L-tyrosine in biological fluids and tissues by isotope dilution liquid chromatography electrospray ionization tandem mass spectrometry. Chem. Res. Toxicol. 2002, 15, 1209-1217.
33. Misra, H. P., Fridovich, I., The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. J. Biol. Chem. 1972, 247, 3170-3175.
34. Gunzler, W. A., Kremers, H., Flohe, L., An improved coupled test procedure for glutathione peroxidase (EC 1-11-1-9-) in blood. Z Klin Chem Klin Biochem 1974, 12, 444-448.
35. Bradford, M. M., A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72, 248-254.
36. Rothe, G., Valet, G., Flow cytometric assays of oxidative burst activity in phagocytes. Methods Enzymol. 1994, 233, 539-548.
37. Miller, N. J., Rice-Evans, C., Davies, M. J., Gopinathan, V., Milner, A., A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates. Clin. Sci. (Lond.) 1993, 84, 407-412.
38. Beutler, E., Duron, O., Kelly, B. M., Improved method for the determination of blood glutathione. J. Lab. Clin. Med. 1963, 61, 882-888.
39. Habig, W. H., Pabst, M. J., Jakoby, W. B., Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 1974, 249, 7130-7139.
40. Dillon, S. A., Lowe, G. M., Billington, D., Rahman, K., Dietary supplementation with aged garlic extract reduces plasma and urine concentrations of 8-iso-prostaglandin F(2 alpha) in smoking and nonsmoking men and women. J. Nutr. 2002, 132, 168-171.
41. O'Brien, P., Procedures for comparing samples with multiple endpoints. Biometrics 1984, 40, 1079-1087.
42. Tang, D.-I., Geller, N. L., Pocock, S. J., On the design and analysis of randomized clinical trials with multiple endpoints. Biometrics 1993, 49, 23-30.
43. Hodges, J. L., Lehmann, E. L., Estimates of Location Based on Rank Tests. Ann. Math. Stat. 1963, 34, 598-611.
44. Huber, W. W., Parzefall, W., Modification of N-acetyltransferases and glutathione S-transferases by coffee components: possible relevance for cancer risk. Methods Enzymol. 2005, 401, 307-341.
45. van Zeeland, A. A., de Groot, A. J., Hall, J., Donato, F., 8-Hydroxydeoxyguanosine in DNA from leukocytes of healthy adults: relationship with cigarette smoking, environmental tobacco smoke, alcohol and coffee consumption. Mutat. Res. 1999, 439, 249-257.
46. Montuschi, P., Barnes, P. J., Roberts, L. J., 2nd, Isoprostanes: markers and mediators of oxidative stress. FASEB J. 2004, 18, 1791-1800.
47. Richelle, M., Tavazzi, I., Offord, E., Comparison of the antioxidant activity of commonly consumed polyphenolic beverages (coffee, cocoa, and tea) prepared per cup serving. J. Agric. Food Chem. 2001, 49, 3438-3442.
48. Gomez-Ruiz, J. A., Leake, D. S., Ames, J. M., In vitro antioxidant activity of coffee compounds and their metabolites. J. Agric. Food Chem. 2007, 55, 6962-6969.
49. Mursu, J., Voutilainen, S., Nurmi, T., Alfthan, G., et al., The effects of coffee consumption on lipid peroxidation and plasma total homocysteine concentrations: a clinical trial. Free Radic. Biol. Med. 2005, 38, 527-534.
50. Kono, Y., Shibata, H., Kodama, Y., Sawa, Y., The suppression of the N-nitrosating reaction by chlorogenic acid. Biochem. J. 1995, 312, 947-953.
51. Pacher, P., Beckman, J. S., Liaudet, L., Nitric oxide and peroxynitrite in health and disease. Physiol. Rev. 2007, 87, 315-424.
52. Suzuki, A., Yamamoto, N., Jokura, H., Yamamoto, M., et al., Chlorogenic acid attenuates hypertension and improves endothelial function in spontaneously hypertensive rats. J. Hypertens. 2006, 24, 1065-1073.
53. Esposito, F., Morisco, F., Verde, V., Ritieni, A., et al., Moderate coffee consumption increases plasma glutathione but not homocysteine in healthy subjects. Aliment. Pharmacol. Ther. 2003, 17, 595-601.
54. Steinkellner, H., Hoelzl, C., Uhl, M., Cavin, C., et al., Coffee consumption induces GSTP in plasma and protects lymphocytes against (+/-)-anti-benzo[a]pyrene-7, 8-dihydrodiol-9, 10-epoxide induced DNA-damage: Results of controlled human intervention trials. Mutat. Res. 2005, 591, 264-275.
55. Nardini, M., Cirillo, E., Natella, F., Scaccini, C., Absorption of phenolic acids in humans after coffee consumption. J. Agric. Food Chem. 2002, 50, 5735-5741.
56. Renouf, M., Guy, P. A., Marmet, C., Fraering, A.-L., et al., Measurements of caffeic and ferulic acid equivalents in plasma after coffee consumption: small intestine and colon are key sites for coffee metabolism. Mol. Nutr. Food Res. 2010, 54, 760-766.
57. Stalmach, A., Mullen, W., Barron, D., Uchida, K., et al., Metabolite profiling of hydroxycinnamate derivatives in plasma and urine following the ingestion of coffee by humans: identification of biomarkers of coffee consumption. Drug Met. Disp. 2009, 37, 1-10.
58. Wittemer, S. M., Ploch, M., Windeck, T., Muller, S. C., et al., Bioavailability and pharmacokinetics of caffeoylquinic acids and flavonoids after oral administration of Artichoke leaf extracts in humans. Phytomedicine 2005, 12, 28-38.
59. Bakuradze, T., Baum, M., Eisenbrand, G., Janzowksi, C., in: Williamson, G., Day, A. (Eds.), 4th International Conference on Polyphenols and Health, University of Leeds, Leeds 2009, p. 266.
60. Johnston, K. L., Clifford, M. N., Morgan, L. M., Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeine. Am. J. Clin. Nutr. 2003, 78, 728-733.
61. Serrano, J., Boada, J., Ayala, V., Gonzalo, H., et al., COST B35 conference, lipid peroxidation associated disorders, development and validation of novel antioxidant substances for the prevention of lipid peroxidation, Kaunas, Lithuania 2008.
62. Dotan, Y., Lichtenberg, D., Pinchuk, I., Lipid peroxidation cannot be used as a universal criterion of oxidative stress. Prog. Lipid Res. 2004, 43, 200-227.
63. Nersesyan, A., Hoelzl, C., Ferk, F., Misik, M., Knasmüller, S., in: Dhawan, A., Anderson D. (Eds.), The Comet Assay in Toxicology, Royal Society of Chemistry, Cambridge, UK 2009, pp. 267-296.