Mitochondria-mediated apoptosis was induced by oleuropein in H1299 cells involving activation of p38 MAP kinase

Journal of Cellular Biochemistry

Volumn 120, Issue 4, 2019, Pages 5480-5494

  Wang, Wang ^a   Wu, Jibing ^a   Zhang, Qingyan ^a   Li, Xue ^a   Zhu, Xixi ^a   Wang, Qiuying ^a   Cao, Shasha ^a   Du, Linfang ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

apoptosis; H1299 cells; mitochondria pathway; oleuropein; p38 MAPK

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CASPASE 3; CYTOCHROME C; MITOGEN ACTIVATED PROTEIN KINASE P38; NEUROPSIN; OLEUROPEIN; PROTEIN BCL 2; PROTEIN C JUN; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTOME; IRIDOID; TUMOR PROTEIN;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL SURVIVAL; DENSITOMETRY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION ASSAY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; G2 PHASE CELL CYCLE CHECKPOINT; GADD45A GENE; GENE; GENE EXPRESSION; GENE MAPPING; GENE ONTOLOGY; HUMAN; HUMAN CELL; LARGE CELL LUNG CARCINOMA; MAPK SIGNALING; NCI-H1299 CELL LINE; NEXT GENERATION SEQUENCING; POLYMERASE CHAIN REACTION; PROTEIN PHOSPHORYLATION; QUALITY CONTROL; RNA SEQUENCE; RPS6A5 GENE; UPREGULATION; WESTERN BLOTTING; DRUG EFFECT; GENE EXPRESSION REGULATION; LUNG TUMOR; METABOLISM; MITOCHONDRION; PATHOLOGY; TUMOR CELL LINE;

APOPTOSIS; CELL LINE, TUMOR; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IRIDOIDS; LUNG NEOPLASMS; MAP KINASE SIGNALING SYSTEM; MITOCHONDRIA; NEOPLASM PROTEINS; P38 MITOGEN-ACTIVATED PROTEIN KINASES;

EID: 85060988657     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.27827     Document Type: Article

References (48)

1. Nagler R, Cohen S, Gavish M. The effect of cigarette smoke on the translocator protein (TSPO) in cultured lung cancer cells. J Cell Biochem. 2015;116:2786-2792.
2. Schütz A, Röser K, Klitzsch J, et al. Lung adenocarcinomas and lung cancer cell lines show association of MMP-1 expression with STAT3 activation 1. Transl Oncol. 2015;8:97-105.
3. Hsieh YS, Liao CH, Chen WS, Pai JT, Weng MS. Shikonin inhibited migration and invasion of human lung cancer cells via suppression of c-Met-mediated epithelial-to-mesenchymal transition. J Cell Biochem. 2017;118:4639-4651.
4. Cao S, Zhu X, Du L. P38 MAP kinase is involved in oleuropein-induced apoptosis in A549 cells by a mitochondrial apoptotic cascade. Biomed Pharmacother. 2017;95:1425-1435.
5. Fabiani R, De bartolomeo A, Rosignoli P, et al. Virgin olive oil phenols inhibit proliferation of human promyelocytic leukemia cells (HL60) by inducing apoptosis and differentiation. J Nutr. 2006;136:614-619.
6. Jemai H, El Feki A, Sayadi S. Antidiabetic and antioxidant effects of hydroxytyrosol and oleuropein from olive leaves in alloxan-diabetic rats. J Agric Food Chem. 2009;57:8798-8804.
7. Bogani P, Galli C, Villa M, Visioli F. Postprandial anti-inflammatory and antioxidant effects of extra virgin olive oil. Atherosclerosis. 2007;190:181-186.
8. Warleta F, Quesada CS, Campos M, Allouche Y, Beltrán G, Gaforio JJ. Hydroxytyrosol protects against oxidative DNA damage in human breast cells. Nutrients. 2011;3:839-857.
9. Yao J, Wu J, Yang X, Yang J, Zhang Y, Du L. Oleuropein induced apoptosis in HeLa cells via a mitochondrial apoptotic cascade associated with activation of the c-Jun NH2-terminal kinase. J Pharmacol Sci. 2014;125:300-11.
10. Chang L, Karin M. Mammalian MAP kinase signalling cascades. Nature. 2001;410:37-40.
11. Ono K, Han J. The p38 signal transduction pathway: activation and function. Cell Signal. 2000;12:1-13.
12. Kim BJ, Ryu SW, Song BJ. JNK- and p38 kinase-mediated phosphorylation of bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells. J Biol Chem. 2006;281:21256-21265.
13. Ansorge WJ. Next-generation DNA sequencing techniques. New Biotechnol. 2009;25:195-203.
14. Mao W, Shi H, Chen X, et al. Anti-proliferation and migration effects of oleuropein on human A549 lung carcinoma cells. Lat Am J Pharm. 2012;31:1217-1221.
15. Walker JM, Kruger NJ. Basic Protein and Peptide Protocols, Totowa, NJ: Humana Press. 1994:9-15. (The Bradford method for protein quantitation).
16. Andrews S 2010. FastQC: a quality control tool for high throughput sequence data.
17. Bolger AM, Lohse M, Usadel B. Trimmomatic: a flexible trimmer for Illumina sequence data. Bioinformatics. 2014;30:2114-2120.
18. Flicek P, Amode MR, Barrell D, et al. Ensembl 2012. Nucleic Acids Res. 2011;40:D84-D90.
19. Langmead B, Salzberg SL. Fast gapped-read alignment with Bowtie 2. Nat Methods. 2012;9:357-359.
20. Kim D, Pertea G, Trapnell C, Pimentel H, Kelley R, Salzberg SL. TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biol. 2013;14:R36.
21. Li B, Dewey CN. RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. BMC Bioinformatics. 2011;12:323.
22. Robinson MD, McCarthy DJ, Smyth GK. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics. 2010;26:139-140.
23. Yu G, Wang L-G, Han Y, He Q-Y. clusterProfiler: an R package for comparing biological themes among gene clusters. OMICA. 2012;16:284-287.
24. Green DR, Reed JC. Mitochondria and apoptosis. Science. 1998;281:1309-1312.
25. Ghasemi A, Hashemy SI, Aghaei M, Panjehpour M. Leptin induces matrix metalloproteinase 7 expression to promote ovarian cancer cell invasion by activating ERK and JNK pathways. J Cell Biochem. 2017;119:2333-2344.
26. Wang G, Sun J, Liu G, Fu Y, Zhang X. Bradykinin promotes cell proliferation, migration, invasion and tumor growth of gastric cancer through ERK signaling pathway. J Cell Biochem. 2017;118:4444-4453.
27. Shannon P, Markiel A, Ozier O, et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res. 2003;13:2498-2504.
28. Salvador JM, Brownclay JD, Fornace AJ Jr. Gadd45 in stress signaling, cell cycle control, and apoptosis. Adv Exp Med Biol. 2013;793:1-19.
29. Deak M, Clifton AD, Lucocq JM, Alessi DR. Mitogen-and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB. EMBO J. 1998;17:4426-4441.
30. Liu F, Gore AJ, Wilson JL, Korc M. DUSP1 is a novel target for enhancing pancreatic cancer cell sensitivity to gemcitabine. PLoS One. 2014;9:e84982.
31. Serini S, Trombino S, Oliva F, et al. Docosahexaenoic acid induces apoptosis in lung cancer cells by increasing MKP-1 and down-regulating p-ERK1/2 and p-p38 expression. Apoptosis. 2008;13:1172-1183.
32. Fabiani R, Rosignoli P, De bartolomeo A, et al. Oxidative DNA damage is prevented by extracts of olive oil, hydroxytyrosol, and other olive phenolic compounds in human blood mononuclear cells and HL60 cells. J Nutr. 2008;138:1411-1416.
33. Hashim YZHY, Rowland IR, Mcglynn H, et al. Inhibitory effects of olive oil phenolics on invasion in human colon adenocarcinoma cells in vitro. Int J Cancer. 2008;122:495-500.
34. Mijatovic SA, Timotijevic GS, Miljkovic DM, et al. Multiple antimelanoma potential of dry olive leaf extract. Int J Cancer. 2011;128:1955-1965.
35. Bulotta S, Corradino R, Celano M, et al. Antiproliferative and antioxidant effects on breast cancer cells of oleuropein and its semisynthetic peracetylated derivatives. Food Chem. 2011;127:1609-1614.
36. Green DR. Means to an End: Apoptosis and Other Cell Death Mechanisms. New York: Cold Spring Harbor Laboratory; 2011.
37. Elmore S. Apoptosis: a review of programmed cell death. Toxicol Pathol. 2007;35:495-516.
38. Gross A, Jockel J, Wei MC, Korsmeyer SJ. Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis. EMBO J. 1998;17:3878-85.
39. Elamin MH, Daghestani MH, Omer SA, et al. Olive oil oleuropein has anti-breast cancer properties with higher efficiency on ER-negative cells. Food Chem Toxicol. 2013;53:310-316.
40. Chatterjee A, Chatterji U. All-trans retinoic acid ameliorates arsenic-induced oxidative stress and apoptosis in the rat uterus by modulating MAPK signaling proteins. J Cell Biochem. 2017;118:3796-3809.
41. Raingeaud J, Gupta S, Rogers JS, et al. Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J Biol Chem. 1995;270:7420-7426.
42. Bulotta S, Corradino R, Celano M, et al. Antioxidant and antigrowth action of peracetylated oleuropein in thyroid cancer cells. J Mol Endocrinol. 2013;51:181-189.
43. Cárdeno A, Sánchezhidalgo M, Rosillo MA, Alarcón de la Lastra C. Oleuropein, a secoiridoid derived from olive tree, inhibits the proliferation of human colorectal cancer cell through downregulation of HIF-1α. Nutr Cancer. 2013;65:147-156.
44. Corona G, Deiana M, Incani A, Vauzour D, Dessì MA, Spencer JP. Inhibition of p38/CREB phosphorylation and COX-2 expression by olive oil polyphenols underlies their anti-proliferative effects. Biochem Biophys Res Commun. 2007;362:606-611.
45. Han J, Talorete TPN, Yamada P, Isoda H. Anti-proliferative and apoptotic effects of oleuropein and hydroxytyrosol on human breast cancer MCF-7 cells. Cytotechnology. 2009;59:45-53.
46. Fang S, Jin X, Wang R, et al. Polymorphisms in the MMP1 and MMP3 promoter and non-small cell lung carcinoma in North China. Carcinogenesis. 2005;26:481-486.
47. Li S, Zhou W, Park S, et al. Matrix metalloproteinase-1 promoter polymorphism and lung cancer risk. Cancer Epidemiol Biomarkers Prev. 2005;14:567.
48. Samuels Y, Velculescu VE. Oncogenic mutations of PIK3CA in human cancers. Cell Cycle. 2004;3:1221-1224.