Microbiotas from Humans with Inflammatory Bowel Disease Alter the Balance of Gut Th17 and RORγt+ Regulatory T Cells and Exacerbate Colitis in Mice

Immunity

Volumn 50, Issue 1, 2019, Pages 212-224.e4

  Britton, Graham J ^a   Contijoch, Eduardo J ^a   Mogno, Ilaria ^a   Vennaro, Olivia H ^a   Llewellyn, Sean R ^a   Ng, Ruby ^a   Li, Zhihua ^a   Mortha, Arthur ^a,b   Merad, Miriam ^a   Das, Anuk ^c   Gevers, Dirk ^c   McGovern, Dermot P B ^d   Singh, Namita ^d   Braun, Jonathan ^e   Jacobs, Jonathan P ^f   Clemente, Jose C ^a   Grinspan, Ari ^a   Sands, Bruce E ^a   Colombel, Jean Frederic ^a   Dubinsky, Marla C ^a   Faith, Jeremiah J ^a   more..

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^d CEDARS SINAI MEDICAL CENTER   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RETINOID RELATED ORPHAN RECEPTOR GAMMA; RNA 16S;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLITIS; CONTROLLED STUDY; DISEASE EXACERBATION; HUMAN; INFLAMMATORY BOWEL DISEASE; INTESTINE CELL; MICROBIAL COLONIZATION; MICROFLORA; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; TH17 CELL; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; CHEMICALLY INDUCED; DISEASE MODEL; GENETICS; HOMEOSTASIS; IMMUNOLOGY; INTESTINE FLORA; METABOLISM; MICROBIOLOGY;

ANIMALS; CELL DIFFERENTIATION; COLITIS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; GASTROINTESTINAL MICROBIOME; HOMEOSTASIS; HUMANS; INFLAMMATORY BOWEL DISEASES; MICE; MICE, INBRED C57BL; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 3; RNA, RIBOSOMAL, 16S; T-LYMPHOCYTES, REGULATORY; TH17 CELLS;

EID: 85059329854     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2018.12.015     Document Type: Article

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