Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome

Cell

Volumn 167, Issue 2, 2016, Pages 444-456.e14

  Chudnovskiy, Aleksey ^a   Mortha, Arthur ^a,d   Kana, Veronika ^a   Kennard, Andrea ^c   Ramirez, Juan David ^b,c   Rahman, Adeeb ^a   Remark, Romain ^a   Mogno, Ilaria ^a   Ng, Ruby ^a   Gnjatic, Sasha ^a   Amir, El ad David ^a   Solovyov, Alexander ^a   Greenbaum, Benjamin ^a   Clemente, Jose ^a   Faith, Jeremiah ^a   Belkaid, Yasmine ^c   Grigg, Michael E ^c   Merad, Miriam ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b Universidad del Rosario   (Canada)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

colon cancer; commensal protist; gut dendritic cells; gut macrophages; IL 18; IL 1b; inflammasome; intestinal bacterial infection; microbiome; Tritrichomonas musculis

Indexed keywords

ALPHA TUBULIN; APC PROTEIN; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR ATF LIKE 3 PROTEIN; CD45 ANTIGEN; CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CXCR3; GAMMA INTERFERON; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HERMES ANTIGEN; INDUCIBLE NITRIC OXIDE SYNTHASE; INFLAMMASOME; INHIBITOR OF DIFFERENTIATION 2; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 18; INTERLEUKIN 18 RECEPTOR ALPHA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 22; INTERLEUKIN 4; INTERLEUKIN 5; KI 67 ANTIGEN; MALATE DEHYDROGENASE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; ADOLESCENT; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; CD4+ T LYMPHOCYTE; COLON MUCOSA; COLORECTAL TUMOR; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; DIENTAMOEBA; DISEASE EXACERBATION; ENTEROCOLITIS; HOST PARASITE INTERACTION; HUMAN; INFECTION PREVENTION; MICROBIAL COLONIZATION; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM; SALMONELLOSIS; TH1 CELL; TH17 CELL; TRITRICHOMONAS; TRITRICHOMONAS MUSCULIS; ANIMAL; C57BL MOUSE; COLITIS; IMMUNOLOGY; INTESTINE MUCOSA; MICROBIOLOGY; MICROFLORA; PARASITOLOGY; SYMBIOSIS; TRICHOMONAS; TRICHOMONIASIS;

ANIMALS; COLITIS; DIENTAMOEBA; HOST-PARASITE INTERACTIONS; IMMUNITY, MUCOSAL; INFLAMMASOMES; INTERLEUKIN-18; INTESTINAL MUCOSA; MICE; MICE, INBRED C57BL; MICROBIOTA; SALMONELLA INFECTIONS; SALMONELLA TYPHIMURIUM; SYMBIOSIS; TH1 CELLS; TH17 CELLS; TRICHOMONAS; TRICHOMONAS INFECTIONS;

EID: 84990846993     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2016.08.076     Document Type: Article

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