Microbiota-Induced TNF-like Ligand 1A Drives Group 3 Innate Lymphoid Cell-Mediated Barrier Protection and Intestinal T Cell Activation during Colitis

Immunity

Volumn 49, Issue 6, 2018, Pages 1077-1089.e5

  Castellanos, Jim G ^a   Woo, Viola ^a   Viladomiu, Monica ^a   Putzel, Gregory ^a   Lima, Svetlana ^a   Diehl, Gretchen E ^b   Marderstein, Andrew R ^a   Gandara, Jorge ^a   Perez, Alexendar R ^a   Withers, David R ^c   Targan, Stephan R ^d   Shih, David Q ^d   Scherl, Ellen J ^a   Longman, Randy S ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^d CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

Crohn's disease; CX 3 CR1 + mononuclear phagocytes; Inflammatory bowel disease; innate lymphoid cell; TL1A

Indexed keywords

CD11B ANTIGEN; CD14 ANTIGEN; CD19 ANTIGEN; CHEMOKINE RECEPTOR CCR6; CHEMOKINE RECEPTOR CX3CR1; GAMMA INTERFERON; GLYCOPROTEIN P 15095; I KAPPA B KINASE ALPHA; INTERLEUKIN 17; INTERLEUKIN 22; INTERLEUKIN 23; INTERLEUKIN 7 RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; OX40 LIGAND; RETINOID RELATED ORPHAN RECEPTOR GAMMA; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR T BET; TUMO NECROSIS FACTOR LIKE LIGAND 1A; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL GROWTH INHIBITOR; INTERLEUKIN DERIVATIVE; INTERLEUKIN-22;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; COLITIS; CONTROLLED STUDY; CROHN DISEASE; CYTOKINE PRODUCTION; DEXTRAN SULFATE SODIUM-INDUCED COLITIS; FEMALE; GNOTOBIOTICS; HUMAN; HUMAN TISSUE; INTESTINE BIOPSY; LAMINA PROPRIA; LYMPHOID CELL; MALE; MIDDLE AGED; MONONUCLEAR CELL; MONONUCLEAR PHAGOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION; ANIMAL; C57BL MOUSE; CYTOLOGY; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; INTESTINE MUCOSA; KNOCKOUT MOUSE; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; METABOLISM; MICROBIOLOGY; MICROFLORA; PHAGOCYTE; PHYSIOLOGY; T LYMPHOCYTE; TRANSGENIC MOUSE; YOUNG ADULT;

ADULT; AGED; ANIMALS; COLITIS; FEMALE; HUMANS; IMMUNITY, INNATE; INTERLEUKINS; INTESTINAL MUCOSA; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MICROBIOTA; MIDDLE AGED; PHAGOCYTES; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 15; YOUNG ADULT;

EID: 85058883245     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2018.10.014     Document Type: Article

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