Synthesis of 11-carbon terpenoids in yeast using protein and metabolic engineering

Nature Chemical Biology

Volumn 14, Issue 12, 2018, Pages 1090-1098

  Ignea, Codruta ^a,b   Pontini, Marianna ^b,c   Motawia, Mohammed S ^a   Maffei, Massimo E ^c   Makris, Antonios M ^d   Kampranis, Sotirios C ^a,b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b MEDITERRANEAN AGRONOMIC INSTITUTE OF CHANIA   (Greece)

^c UNIVERSITY OF TURIN   (Italy)

^d INFORMATION TECHNOLOGIES INSTITUTE   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHYLGERANYL PYROPHOSPHATE; CARBON 11; PYROPHOSPHORIC ACID DERIVATIVE; SYNTHETASE; TERPENE DERIVATIVE; TERPENE SYNTHASE; TERPENOID DERIVATIVE; UNCLASSIFIED DRUG; DITERPENE; GERANYL DIPHOSPHATE; RECOMBINANT PROTEIN; TERPENE; TRANSFERASE;

ARTICLE; ATOM; BIOLOGICAL ACTIVITY; BIOSYNTHESIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYCLIZATION; ENZYME SPECIFICITY; METABOLIC ENGINEERING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; PSEUDANABAENA LIMNETICA; SYNTHETIC BIOLOGY; YEAST; YEAST CELL; CYANOBACTERIUM; ENZYMOLOGY; GENETICS; METABOLISM; PROCEDURES; SACCHAROMYCES CEREVISIAE; SYNTHESIS;

ALKYL AND ARYL TRANSFERASES; CYANOBACTERIA; DIPHOSPHATES; DITERPENES; METABOLIC ENGINEERING; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SYNTHETIC BIOLOGY; TERPENES;

EID: 85056641180     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/s41589-018-0166-5     Document Type: Article

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