Language delay and poorer school performance in children of mothers with inadequate iodine intake in pregnancy: results from follow-up at 8 years in the Norwegian Mother and Child Cohort Study

European Journal of Nutrition

Volumn 58, Issue 8, 2019, Pages 3047-3058

  Abel, Marianne H ^a,b,c   Brandlistuen, Ragnhild E ^a   Caspersen, Ida H ^a   Aase, Heidi ^a   Torheim, Liv E ^b   Meltzer, Helle Margrete ^a   Brantsaeter, Anne Lise ^a  

^a NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

^b OSLO METROPOLITAN UNIVERSITY   (Norway)

^c TINE SA   (Norway)

Author keywords

Dietary supplements; Iodine; MoBa; Neurodevelopment; Norwegian Mother and Child Cohort Study; Pregnancy

Indexed keywords

IODINE;

ADULT; ARTICLE; CHILD; COHORT ANALYSIS; DIETARY SUPPLEMENT; EDUCATION; FEMALE; FOLLOW UP; FOOD FREQUENCY QUESTIONNAIRE; HUMAN; LANGUAGE ABILITY; LANGUAGE DELAY; LEARNING DISORDER; LITERACY; MAJOR CLINICAL STUDY; MATERNAL NUTRITION; MINERAL SUPPLEMENTATION; MOTHER CHILD RELATION; NORWEGIAN (PEOPLE); PREGNANCY; SCHOOL CHILD; WRITING; ACADEMIC SUCCESS; ADVERSE EVENT; DEVELOPMENTAL LANGUAGE DISORDER; DIET; MOTHER; NORWAY; PREGNANCY COMPLICATION; QUESTIONNAIRE;

ACADEMIC SUCCESS; ADULT; CHILD; COHORT STUDIES; DIET; FEMALE; FOLLOW-UP STUDIES; HUMANS; IODINE; LANGUAGE DEVELOPMENT DISORDERS; MOTHERS; NORWAY; PREGNANCY; PREGNANCY COMPLICATIONS; SURVEYS AND QUESTIONNAIRES;

EID: 85056373369     PISSN: 14366207     EISSN: 14366215     Source Type: Journal    
DOI: 10.1007/s00394-018-1850-7     Document Type: Article

References (46)

1. Velasco I, Bath SC, Rayman MP (2018) Iodine as essential nutrient during the first 1000 days of life. Nutrients. 10.3390/nu10030290
2. Laurberg P, Cerqueira C, Ovesen L, Rasmussen LB, Perrild H, Andersen S, Pedersen IB, Carle A (2010) Iodine intake as a determinant of thyroid disorders in populations. Best Pract Res Clin Endocrinol Metab 24(1):13–27. 10.1016/j.beem.2009.08.013
3. Zimmermann MB, Boelaert K (2015) Iodine deficiency and thyroid disorders. Lancet Diabetes Endocrinol 3(4):286–295. 10.1016/S2213-8587(14)70225-6
4. Shi X, Han C, Li C, Mao J, Wang W, Xie X, Li C, Xu B, Meng T, Du J, Zhang S, Gao Z, Zhang X, Fan C, Shan Z, Teng W (2015) Optimal and safe upper limits of iodine intake for early pregnancy in iodine-sufficient regions: a cross-sectional study of 7190 pregnant women in China. J Clin Endocrinol Metab 100(4):1630–1638. 10.1210/jc.2014-3704
5. Obregon MJ, Escobar del Rey F, Morreale de Escobar G (2005) The effects of iodine deficiency on thyroid hormone deiodination. Thyroid 15(8):917–929. 10.1089/thy.2005.15.917
6. Zimmermann MB (2010) Iodine deficiency in industrialised countries. Proc Nutr Soc 69(1):133–143. 10.1017/S0029665109991819
7. Pearce EN, Andersson M, Zimmermann MB (2013) Global iodine nutrition: Where do we stand in 2013? Thyroid 23(5):523–528
8. Glinoer D (2007) The importance of iodine nutrition during pregnancy. Public Health Nutr 10(12A):1542–1546
9. McLeod DS, McIntyre HD (2010) Subclinical hypothyroidism and related biochemical entities in pregnancy: implications and management. Obstet Med 3(4):139–144. 10.1258/om.2010.100023
10. World Health Organization (2007) Iodine deficiency in Europe: a continuing public health problem. In: Andersson M, de Benoist B, Darnton-Hill I et al (eds) World Health Organization, Geneva
11. Abel MH, Korevaar TIM, Erlund I, Villanger GD, Caspersen IH, Arohonka P, Alexander J, Meltzer HM, Brantsaeter AL (2018) Iodine intake is associated with thyroid function in mild- to moderately iodine deficient pregnant women. Thyroid 28:1359–1371. 10.1089/thy.2018.0305
12. Abel MH, Caspersen IH, Meltzer HM, Haugen M, Brandlistuen RE, Aase H, Alexander J, Torheim LE, Brantsaeter AL (2017) Suboptimal maternal iodine intake is associated with impaired child neurodevelopment at 3 years of age in the Norwegian Mother and Child Cohort Study. J Nutr 147(7):1314–1324. 10.3945/jn.117.250456
13. Abel MH, Ystrom E, Caspersen IH, Meltzer HM, Aase H, Torheim LE, Askeland RB, Reichborn-Kjennerud T, Brantsaeter AL (2017) Maternal iodine intake and offspring attention-deficit/hyperactivity disorder: results from a large prospective cohort study. Nutrients. 10.3390/nu9111239
14. Bath SC, Steer CD, Golding J, Emmett P, Rayman MP (2013) Effect of inadequate iodine status in UK pregnant women on cognitive outcomes in their children: results from the Avon Longitudinal Study of Parents and Children (ALSPAC). Lancet 382(9889):331–337. 10.1016/S0140-6736(13)60436-5
15. Hynes KL, Otahal P, Hay I, Burgess JR (2013) Mild iodine deficiency during pregnancy is associated with reduced educational outcomes in the offspring: 9-year follow-up of the Gestational Iodine Cohort. J Clin Endocrinol Metab 98(5):1954–1962
16. Hynes KL, Otahal P, Burgess JR, Oddy WH, Hay I (2017) Reduced educational outcomes persist into adolescence following mild iodine deficiency in utero, despite adequacy in childhood: 15-year follow-up of the Gestational Iodine Cohort investigating auditory processing speed and working memory. Nutrients. 10.3390/nu9121354
17. Wei W, Wang Y, Dong J, Wang Y, Min H, Song B, Shan Z, Teng W, Xi Q, Chen J (2015) Hypothyroxinemia induced by maternal mild iodine deficiency impairs hippocampal myelinated growth in lactational rats. Environ Toxicol 30(11):1264–1274. 10.1002/tox.21997
18. Monahan M, Boelaert K, Jolly K, Chan S, Barton P, Roberts TE (2015) Costs and benefits of iodine supplementation for pregnant women in a mildly to moderately iodine-deficient population: a modelling analysis. Lancet Diabetes Endocrinol 3(9):715–722. 10.1016/S2213-8587(15)00212-0
19. NNR12 Project Group (2014) Iodine. In: in Nordic nutrition recommendations 2012, integrating nutrition and physical activity, 5th edn. Nordic Council of Ministers, Copenhagen, pp 583–590
20. EFSA NDA Panel (EFSA Panel on Dietetic Products Nutrition and Allergies) (2014) Scientific opinion on dietary reference values for iodine. EFSA J 12(5):3660. 10.2903/j.efsa.2014.3660 doi
21. World Health Organization, United Nations Children’s Fund, International Council for Control of Iodine Deficiency Disorders (2007) Assessment of iodine deficiency disorders and monitoring their elimination: a guide for programme managers, 3rd edn. World Health Organization, Geneva
22. Harding KB, Pena-Rosas JP, Webster AC, Yap CM, Payne BA, Ota E, De-Regil LM (2017) Iodine supplementation for women during the preconception, pregnancy and postpartum period. Cochrane Database Syst Rev 3:CD011761. 10.1002/14651858.CD011761.pub2
23. Rebagliato M, Murcia M, Espada M, Alvarez-Pedrerol M, Bolumar F, Vioque J, Basterrechea M, Blarduni E, Ramon R, Guxens M, Foradada CM, Ballester F, Ibarluzea J, Sunyer J (2010) Iodine intake and maternal thyroid function during pregnancy. Epidemiology 21(1):62–69. 10.1097/EDE.0b013e3181c1592b
24. Moleti M, Di Bella B, Giorgianni G, Mancuso A, De Vivo A, Alibrandi A, Trimarchi F, Vermiglio F (2011) Maternal thyroid function in different conditions of iodine nutrition in pregnant women exposed to mild-moderate iodine deficiency: an observational study. Clin Endocrinol (Oxf) 74(6):762–768. 10.1111/j.1365-2265.2011.04007.x
25. Magnus P, Birke C, Vejrup K, Haugan A, Alsaker E, Daltveit AK, Handal M, Haugen M, Hoiseth G, Knudsen GP, Paltiel L, Schreuder P, Tambs K, Vold L, Stoltenberg C (2016) Cohort profile update: The Norwegian Mother and Child Cohort Study (MoBa). Int J Epidemiol 45(2):382–388. 10.1093/ije/dyw029
26. Irgens LM (2000) The Medical Birth Registry of Norway. Epidemiological research and surveillance throughout 30 years. Acta Obstet Gynecol Scand 79(6):435–439
27. Vrijheid M, Slama R, Robinson O, Chatzi L, Coen M, van den Hazel P, Thomsen C, Wright J, Athersuch TJ, Avellana N, Basagana X, Brochot C, Bucchini L, Bustamante M, Carracedo A, Casas M, Estivill X, Fairley L, van Gent D, Gonzalez JR, Granum B, Grazuleviciene R, Gutzkow KB, Julvez J, Keun HC, Kogevinas M, McEachan RR, Meltzer HM, Sabido E, Schwarze PE, Siroux V, Sunyer J, Want EJ, Zeman F, Nieuwenhuijsen MJ (2014) The human early-life exposome (HELIX): project rationale and design. Environ Health Perspect 122(6):535–544. 10.1289/ehp.1307204
28. Norwegian Institute of Public Health Website (2017) MoBa Food Frequency Questionnaire (English translation). http://www.webcitation.org/6u5JMPcZg. Accessed 9 Oct 2017
29. Meltzer HM, Brantsaeter AL, Ydersbond TA, Alexander J, Haugen M (2008) Methodological challenges when monitoring the diet of pregnant women in a large study: experiences from the Norwegian Mother and Child Cohort Study (MoBa). Matern Child Nutr 4(1):14–27. 10.1111/j.1740-8709.2007.00104.x
30. Dahl L, Johansson L, Julshamn K, Meltzer HM (2004) The iodine content of Norwegian foods and diets. Public Health Nutr 7(4):569–576. 10.1079/PHN2003554
31. Dahl L, Opsahl JA, Meltzer HM, Julshamn K (2003) Iodine concentration in Norwegian milk and dairy products. Br J Nutr 90(3):679–685
32. Haugen M, Brantsaeter AL, Alexander J, Meltzer HM (2008) Dietary supplements contribute substantially to the total nutrient intake in pregnant Norwegian women. Ann Nutr Metab 52(4):272–280. 10.1159/000146274
33. Brantsaeter AL, Haugen M, Alexander J, Meltzer HM (2008) Validity of a new food frequency questionnaire for pregnant women in the Norwegian Mother and Child Cohort Study (MoBa). Matern Child Nutr 4(1):28–43. 10.1111/j.1740-8709.2007.00103.x
34. Brantsaeter AL, Haugen M, Hagve TA, Aksnes L, Rasmussen SE, Julshamn K, Alexander J, Meltzer HM (2007) Self-reported dietary supplement use is confirmed by biological markers in the Norwegian Mother and Child Cohort Study (MoBa). Ann Nutr Metab 51(2):146–154. 10.1159/000103275
35. Brantsaeter AL, Haugen M, Julshamn K, Alexander J, Meltzer HM (2009) Evaluation of urinary iodine excretion as a biomarker for intake of milk and dairy products in pregnant women in the Norwegian Mother and Child Cohort Study (MoBa). Eur J Clin Nutr 63(3):347–354. 10.1038/sj.ejcn.1602952
36. Bishop DVM (2003) Children’s communication checklist, 2nd edn. Pearson Assessments, London
37. Bishop DV, Laws G, Adams C, Norbury CF (2006) High heritability of speech and language impairments in 6-year-old twins demonstrated using parent and teacher report. Behav Genet 36(2):173–184. 10.1007/s10519-005-9020-0
38. Norbury CF, Nash M, Baird G, Bishop D (2004) Using a parental checklist to identify diagnostic groups in children with communication impairment: a validation of the Children’s Communication Checklist-2. Int J Lang Commun Disord 39(3):345–364. 10.1080/13682820410001654883
39. Sparrow SS, Cicchetti DV, Balla DA (2005) Vineland Adaptive Behaviour Scale-II. American Guidance Service, Minnesota
40. Pearce EN, Caldwell KL (2016) Urinary iodine, thyroid function, and thyroglobulin as biomarkers of iodine status. Am J Clin Nutr 104(Suppl 3):898S–901S. 10.3945/ajcn.115.110395
41. Konig F, Andersson M, Hotz K, Aeberli I, Zimmermann MB (2011) Ten repeat collections for urinary iodine from spot samples or 24-hour samples are needed to reliably estimate individual iodine status in women. J Nutr 141(11):2049–2054. 10.3945/jn.111.144071
42. Aburto N, Abudou M, Candeias V, Wu T (2014) Effect and safety of salt iodization to prevent iodine deficiency disorders: a systematic review with meta-analyses. World Health Organization, Geneva
43. Brantsaeter AL, Abel MH, Haugen M, Meltzer HM (2013) Risk of suboptimal iodine intake in pregnant Norwegian women. Nutrients 5(2):424–440. 10.3390/nu5020424
44. Nilsen RM, Vollset SE, Gjessing HK, Skjaerven R, Melve KK, Schreuder P, Alsaker ER, Haug K, Daltveit AK, Magnus P (2009) Self-selection and bias in a large prospective pregnancy cohort in Norway. Paediatr Perinat Epidemiol 23(6):597–608. 10.1111/j.1365-3016.2009.01062.x
45. Mann CJ (2003) Observational research methods. Research design II: cohort, cross sectional, and case–control studies. Emerg Med J 20(1):54–60
46. Zimmermann MB, Gizak M, Abbott K, Andersson M, Lazarus JH (2015) Iodine deficiency in pregnant women in Europe. Lancet Diabetes Endocrinol. 10.1016/S2213-8587(15)00263-6