Hypothyroxinemia induced by maternal mild iodine deficiency impairs hippocampal myelinated growth in lactational rats

Environmental Toxicology

Volumn 30, Issue 11, 2015, Pages 1264-1274

  Wei, Wei ^a   Wang, Yi ^a   Dong, Jing ^a   Wang, Yuan ^a   Min, Hui ^a   Song, Binbin ^a   Shan, Zhongyan ^a   Teng, Weiping ^a   Xi, Qi ^b   Chen, Jie ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Hippocampus; Hypothyroxinemia; Iodine deficiency; Myelinated growth

Indexed keywords

BRAIN; IODINE; PHYSIOLOGY; PROTEINS; RATS;

DEVELOPED COUNTRIES; EXPERIMENTAL GROUPS; FEMALE WISTAR RATS; HIPPOCAMPUS; HYPOTHYROXINEMIA; LEARNING AND MEMORY FUNCTIONS; MYELIN BASIC PROTEIN; NEUROLOGICAL DEFICIT;

CHEMICAL CONTAMINATION;

MYELIN; MYELIN BASIC PROTEIN; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2; IODIDE; IODINE;

ABNORMALLY LOW SUBSTRATE CONCENTRATION IN BLOOD; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; CONTROLLED STUDY; DISORDERS OF HORMONE METABOLISM; FEMALE; HIPPOCAMPUS; HYPOTHYROIDISM; HYPOTHYROXINEMIA; IODINE DEFICIENCY; LACTATION; MALE; MYELIN SHEATH; MYELINATION; NERVE CELL DIFFERENTIATION; NEUROLOGIC DISEASE; NEWBORN; NONHUMAN; OLIGODENDROCYTE PRECURSOR CELL; OLIGODENDROGLIA; PERINATAL PERIOD; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION; RAT; THYROID DISEASE; THYROXINE BLOOD LEVEL; ANIMAL; COMPLICATION; DEFICIENCY; EMBRYOLOGY; ETIOLOGY; FETOMATERNAL TRANSFUSION; GROWTH, DEVELOPMENT AND AGING; HUMAN; MATERNAL EXPOSURE; METABOLISM; PREGNANCY; PRENATAL EXPOSURE; WISTAR RAT;

RATTUS; RATTUS NORVEGICUS;

ANIMALS; FEMALE; HIPPOCAMPUS; HUMANS; HYPOTHYROIDISM; IODIDES; IODINE; LACTATION; MATERNAL EXPOSURE; MATERNAL-FETAL EXCHANGE; MYELIN SHEATH; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, WISTAR;

EID: 84944276409     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.21997     Document Type: Article

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