Cyclosporine biosynthesis in Tolypocladium inflatum benefits fungal adaptation to the environment

mBio

Volumn 9, Issue 5, 2018, Pages

  Yang, Xiuqing ^a,b   Feng, Peng ^a   Yin, Ying ^a   Bushley, Kathryn ^c   Spatafora, Joseph W ^d   Wang, Chengshu ^a,e  

^a INSTITUTE OF PLANT PHYSIOLOGY AND ECOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c UNIVERSITY OF MINNESOTA   (United States)

^d OREGON STATE UNIVERSITY   (United States)

^e SHANGHAITECH UNIVERSITY   (China)

Author keywords

Antifungal activity; Biosynthetic pathway; Cyclosporine; Tolypocladium inflatum; Virulence

Indexed keywords

ABC TRANSPORTER; ALANINE; ALANINE RACEMASE; AMINOTRANSFERASE; CYCLOPHILIN; CYCLOSPORIN B; CYCLOSPORIN C; CYCLOSPORINE; CYTOCHROME P450; NONRIBOSOMAL PEPTIDE SYNTHETASE; POLYKETIDE SYNTHASE; TRANSCRIPTION FACTOR; ANTIFUNGAL AGENT; ENZYME; FUNGAL PROTEIN;

ARTICLE; ASPERGILLUS FLAVUS; CATALYSIS; CONTROLLED STUDY; DRUG SYNTHESIS; EVOLUTIONARY ADAPTATION; FILAMENTOUS FUNGUS; FUNGAL GENE; FUNGAL GENOME; FUNGAL VIRULENCE; GENE CLUSTER; GENE DELETION; GENE LOCATION; HOMOLOGOUS RECOMBINATION; INSECT; MUTANT; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; RNA SEQUENCE; SEQUENCE HOMOLOGY; SIMA GENE; SIMB GENE; SIMC GENE; SIMD GENE; SIMG GENE; SIMI GENE; SIMJ GENE; SIML GENE; TINF06009 GENE; TOLYPOCLADIUM INFLATUM; TRANSCRIPTION REGULATION; WILD TYPE; ADAPTATION; ANIMAL; ANTIBIOSIS; BIOSYNTHESIS; DRUG TOLERANCE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HYPOCREALES; METABOLISM; MICROBIOLOGY; MULTIGENE FAMILY; PHYSIOLOGY;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; ANTIBIOSIS; ANTIFUNGAL AGENTS; BIOSYNTHETIC PATHWAYS; CYCLOSPORINE; DRUG TOLERANCE; ENZYMES; FUNGAL PROTEINS; GENE DELETION; GENE EXPRESSION REGULATION, FUNGAL; HYPOCREALES; INSECTA; MULTIGENE FAMILY; TRANSCRIPTION, GENETIC;

EID: 85054397304     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.01211-18     Document Type: Article

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