The IL-4/STAT6/PPARγ signaling axis is driving the expansion of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages

Nucleic Acids Research

Volumn 46, Issue 9, 2018, Pages 4425-4439

  Daniel, Bence ^a,b   Nagy, Gergely ^b   Horvath, Attila ^b   Czimmerer, Zsolt ^b   Cuaranta Monroy, Ixchelt ^b   Poliska, Szilard ^b   Hays, Tristan T ^a   Sauer, Sascha ^c,d,e   Francois Deleuze, Jean ^f   Nagy, Laszlo ^a,b  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF DEBRECEN   (Hungary)

^c MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^d UNIVERSITY OF WÜRZBURG   (Germany)

^e MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^f DIF   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HETERODIMER; INTERLEUKIN 4; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RETINOID X RECEPTOR; STAT6 PROTEIN; TRANSCRIPTION FACTOR; LIGAND; RNA POLYMERASE II; STAT6 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CELL PLASTICITY; CHROMATIN ASSEMBLY AND DISASSEMBLY; COMPLEX FORMATION; CONTROLLED STUDY; GENOMICS; MACROPHAGE; MOUSE; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; CELL CULTURE; CHROMATIN; ENHANCER REGION; ENZYMOLOGY; GENE REGULATORY NETWORK; GENETICS; KNOCKOUT MOUSE; MALE; METABOLISM; PHYSIOLOGY;

ANIMALS; CELLS, CULTURED; CHROMATIN; CHROMATIN ASSEMBLY AND DISASSEMBLY; ENHANCER ELEMENTS, GENETIC; GENE REGULATORY NETWORKS; INTERLEUKIN-4; LIGANDS; MACROPHAGES; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; PPAR GAMMA; RETINOID X RECEPTORS; RNA POLYMERASE II; SIGNAL TRANSDUCTION; STAT6 TRANSCRIPTION FACTOR;

EID: 85054167767     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gky157     Document Type: Article

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