-
1
-
-
0029584593
-
Nonsteroid nuclear receptors: What are genetic studies telling us about their role in real life?
-
Kastner P, Mark M, Chambon P (1995) Nonsteroid nuclear receptors: What are genetic studies telling us about their role in real life? Cell 83:859-869.
-
(1995)
Cell
, vol.83
, pp. 859-869
-
-
Kastner, P.1
Mark, M.2
Chambon, P.3
-
2
-
-
1642457242
-
Nuclear receptor signaling in macrophages
-
Valledor AF, Ricote M (2004) Nuclear receptor signaling in macrophages. Biochem Pharmacol 67:201-212.
-
(2004)
Biochem Pharmacol
, vol.67
, pp. 201-212
-
-
Valledor, A.F.1
Ricote, M.2
-
3
-
-
0036779687
-
Emerging roles of PPARs in inflammation and immunity
-
Daynes RA, Jones DC (2002) Emerging roles of PPARs in inflammation and immunity. Nat Rev Immunol 2:748-759.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 748-759
-
-
Daynes, R.A.1
Jones, D.C.2
-
4
-
-
0029562554
-
The RXR heterodimers and orphan receptors
-
Mangelsdorf DJ, Evans RM (1995) The RXR heterodimers and orphan receptors. Cell 83:841-850.
-
(1995)
Cell
, vol.83
, pp. 841-850
-
-
Mangelsdorf, D.J.1
Evans, R.M.2
-
6
-
-
0026760460
-
Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid
-
Zhang X-K, et al. (1992) Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid. Nature 358:587-591.
-
(1992)
Nature
, vol.358
, pp. 587-591
-
-
Zhang, X.-K.1
-
7
-
-
2942621879
-
In vivo activation of PPAR target genes by RXR homodimers
-
IJpenberg A, et al. (2004) In vivo activation of PPAR target genes by RXR homodimers. EMBO J 23:2083-2091.
-
(2004)
EMBO J
, vol.23
, pp. 2083-2091
-
-
IJpenberg, A.1
-
8
-
-
0026597950
-
Characterization of three RXR genes that mediate the action of 9-cis retinoic acid
-
Mangelsdorf DJ, et al. (1992) Characterization of three RXR genes that mediate the action of 9-cis retinoic acid. Genes Dev 6:329-344.
-
(1992)
Genes Dev
, vol.6
, pp. 329-344
-
-
Mangelsdorf, D.J.1
-
9
-
-
33751531527
-
Normal hematopoiesis after conditional targeting of RXRalpha in murine hematopoietic stem/progenitor cells
-
DOI 10.1189/jlb.0206097
-
Ricote M, et al. (2006) Normal hematopoiesis after conditional targeting of RXRalpha in murine hematopoietic stem/progenitor cells. J Leukoc Biol 80:850-861. (Pubitemid 44835903)
-
(2006)
Journal of Leukocyte Biology
, vol.80
, Issue.4
, pp. 850-861
-
-
Ricote, M.1
Snyder, C.S.2
Leung, H.-Y.3
Chen, J.4
Chien, K.R.5
Glass, C.K.6
-
10
-
-
0026570218
-
9-cis retinoic acid is a high affinity ligand for the retinoid X receptor
-
Heyman RA, et al. (1992) 9-cis retinoic acid is a high affinity ligand for the retinoid X receptor. Cell 68:397-406.
-
(1992)
Cell
, vol.68
, pp. 397-406
-
-
Heyman, R.A.1
-
11
-
-
4043140077
-
Polyunsaturated fatty acids including docosahexaenoic and arachidonic acid bind to the retinoid X receptor alpha ligand-binding domain
-
DOI 10.1074/mcp.M400003-MCP200
-
Lengqvist J, et al. (2004) Polyunsaturated fatty acids including docosahexaenoic and arachidonic acid bind to the retinoid X receptor alpha ligand-binding domain. Mol Cell Proteomics 3:692-703. (Pubitemid 39077000)
-
(2004)
Molecular and Cellular Proteomics
, vol.3
, Issue.7
, pp. 692-703
-
-
Lengqvist, J.1
Mata De Urquiza, A.2
Bergman, A.-C.3
Willson, T.M.4
Sjovall, J.5
Perlmann, T.6
Griffiths, W.J.7
-
12
-
-
0029740183
-
Activation of specific RXR heterodimers by an antagonist of RXR homodimers
-
Lala DS, et al. (1996) Activation of specific RXR heterodimers by an antagonist of RXR homodimers. Nature 383:450-453.
-
(1996)
Nature
, vol.383
, pp. 450-453
-
-
Lala, D.S.1
-
13
-
-
34848834842
-
RAR and RXR modulation in cancer and metabolic disease
-
DOI 10.1038/nrd2397, PII NRD2397
-
Altucci L, Leibowitz MD, Ogilvie KM, de Lera AR, Gronemeyer H (2007) RAR and RXR modulation in cancer and metabolic disease. Nat Rev Drug Discov 6:793-810. (Pubitemid 47504871)
-
(2007)
Nature Reviews Drug Discovery
, vol.6
, Issue.10
, pp. 793-810
-
-
Altucci, L.1
Leibowitz, M.D.2
Ogilvie, K.M.3
De Lera, A.R.4
Gronemeyer, H.5
-
14
-
-
35349016235
-
Recognition of microorganisms and activation of the immune response
-
DOI 10.1038/nature06246, PII NATURE06246
-
Medzhitov R (2007) Recognition of microorganisms and activation of the immune response. Nature 449:819-826. (Pubitemid 47598622)
-
(2007)
Nature
, vol.449
, Issue.7164
, pp. 819-826
-
-
Medzhitov, R.1
-
15
-
-
47949099098
-
Origin and physiological roles of inflammation
-
Medzhitov R (2008) Origin and physiological roles of inflammation. Nature 454:428-435.
-
(2008)
Nature
, vol.454
, pp. 428-435
-
-
Medzhitov, R.1
-
16
-
-
30044438392
-
Dampening inflammation
-
Henson PM (2005) Dampening inflammation. Nat Immunol 6:1179-1181.
-
(2005)
Nat Immunol
, vol.6
, pp. 1179-1181
-
-
Henson, P.M.1
-
17
-
-
0037426726
-
The pathophysiology and treatment of sepsis
-
Hotchkiss RS, Karl IE (2003) The pathophysiology and treatment of sepsis. N Engl J Med 348:138-150.
-
(2003)
N Engl J Med
, vol.348
, pp. 138-150
-
-
Hotchkiss, R.S.1
Karl, I.E.2
-
19
-
-
32144454172
-
The many roles of chemokines and chemokine receptors in inflammation
-
Charo IF, Ransohoff RM (2006) The many roles of chemokines and chemokine receptors in inflammation. N Engl J Med 354:610-621.
-
(2006)
N Engl J Med
, vol.354
, pp. 610-621
-
-
Charo, I.F.1
Ransohoff, R.M.2
-
20
-
-
27144512697
-
Chemokines provide the sustained inflammatory bridge between innate and acquired immunity
-
Coelho AL, Hogaboam CM, Kunkel SL (2005) Chemokines provide the sustained inflammatory bridge between innate and acquired immunity. Cytokine Growth Factor Rev 16:553-560.
-
(2005)
Cytokine Growth Factor Rev
, vol.16
, pp. 553-560
-
-
Coelho, A.L.1
Hogaboam, C.M.2
Kunkel, S.L.3
-
21
-
-
25444448223
-
A Nuclear Receptor Atlas: Macrophage activation
-
Barish GD, et al. (2005) A Nuclear Receptor Atlas: Macrophage activation. Mol Endocrinol 19:2466-2477.
-
(2005)
Mol Endocrinol
, vol.19
, pp. 2466-2477
-
-
Barish, G.D.1
-
22
-
-
33644651160
-
Liver X receptors as integrators of metabolic and inflammatory signaling
-
DOI 10.1172/JCI27883
-
Zelcer N, Tontonoz P (2006) Liver X receptors as integrators of metabolic and inflammatory signaling. J Clin Invest 116:607-614. (Pubitemid 43326865)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.3
, pp. 607-614
-
-
Zelcer, N.1
Tontonoz, P.2
-
23
-
-
29744432867
-
An essential role for Rxralpha in the development of Th2 responses
-
DOI 10.1002/eji.200535366
-
Du X, et al. (2005) An essential role for Rxr alpha in the development of Th2 responses. Eur J Immunol 35:3414-3423. (Pubitemid 43025522)
-
(2005)
European Journal of Immunology
, vol.35
, Issue.12
, pp. 3414-3423
-
-
Du, X.1
Tabeta, K.2
Mann, N.3
Crozat, K.4
Mudd, S.5
Beutler, B.6
-
24
-
-
0034717067
-
The acute phase response is associated with retinoid X receptor repression in rodent liver
-
DOI 10.1074/jbc.M000953200
-
Beigneux AP, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR (2000) The acute phase response is associated with retinoid X receptor repression in rodent liver. J Biol Chem 275:16390-16399. (Pubitemid 30366957)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.21
, pp. 16390-16399
-
-
Beigneux, A.P.1
Moser, A.H.2
Shigenaga, J.K.3
Grunfeld, C.4
Feingold, K.R.5
-
25
-
-
33751531470
-
A role for IRF3-dependent RXRalpha repression in hepatotoxicity associated with viral infections
-
Chow EK, et al. (2006) A role for IRF3-dependent RXRalpha repression in hepatotoxicity associated with viral infections. J Exp Med 203:2589-2602.
-
(2006)
J Exp Med
, vol.203
, pp. 2589-2602
-
-
Chow, E.K.1
-
26
-
-
33744957050
-
Nuclear export of retinoid X receptor alpha in response to interleukin-1beta-mediated cell signaling: Roles for JNK and SER260
-
Zimmerman TL, Thevananther S, Ghose R, Burns AR, Karpen SJ (2006) Nuclear export of retinoid X receptor alpha in response to interleukin-1beta-mediated cell signaling: Roles for JNK and SER260. J Biol Chem 281:15434-15440.
-
(2006)
J Biol Chem
, vol.281
, pp. 15434-15440
-
-
Zimmerman, T.L.1
Thevananther, S.2
Ghose, R.3
Burns, A.R.4
Karpen, S.J.5
-
27
-
-
26844449311
-
Retinoid X receptor ablation in adult mouse keratinocytes generates an atopic dermatitis triggered by thymic stromal lymphopoietin
-
Li M, et al. (2005) Retinoid X receptor ablation in adult mouse keratinocytes generates an atopic dermatitis triggered by thymic stromal lymphopoietin. Proc Natl Acad Sci USA 102:14795-14800.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 14795-14800
-
-
Li, M.1
-
28
-
-
0028784508
-
Molecular cloning and functional characterization of a novel member of the C-C chemokine family
-
Hara T, et al. (1995) Molecular cloning and functional characterization of a novel member of the C-C chemokine family. J Immunol 155:5352-5358.
-
(1995)
J Immunol
, vol.155
, pp. 5352-5358
-
-
Hara, T.1
-
29
-
-
0033563003
-
Immunomodulatory role of C10 chemokine in a murine model of allergic bronchopulmonary aspergillosis
-
Hogaboam CM, et al. (1999) Immunomodulatory role of C10 chemokine in a murine model of allergic bronchopulmonary aspergillosis. J Immunol 162:6071-6079.
-
(1999)
J Immunol
, vol.162
, pp. 6071-6079
-
-
Hogaboam, C.M.1
-
30
-
-
0042834355
-
CCL9 is secreted by the follicle-associated epithelium and recruits dome region Peyer's patch CD11b+ dendritic cells
-
Zhao X, et al. (2003) CCL9 is secreted by the follicle-associated epithelium and recruits dome region Peyer's patch CD11b+ dendritic cells. J Immunol 171:2797-2803.
-
(2003)
J Immunol
, vol.171
, pp. 2797-2803
-
-
Zhao, X.1
-
31
-
-
0033784259
-
Chemokine C10 promotes disease resolution and survival in an experimental model of bacterial sepsis
-
Steinhauser ML, et al. (2000) Chemokine C10 promotes disease resolution and survival in an experimental model of bacterial sepsis. Infect Immun 68:6108-6114.
-
(2000)
Infect Immun
, vol.68
, pp. 6108-6114
-
-
Steinhauser, M.L.1
-
32
-
-
10944258839
-
Role of CC chemokine CCL6/C10 as a monocyte chemoattractant in a murine acute peritonitis
-
LaFleur AM, Lukacs NW, Kunkel SL, Matsukawa A (2004) Role of CC chemokine CCL6/C10 as a monocyte chemoattractant in a murine acute peritonitis. Mediators Inflamm 13:349-355.
-
(2004)
Mediators Inflamm
, vol.13
, pp. 349-355
-
-
LaFleur, A.M.1
Lukacs, N.W.2
Kunkel, S.L.3
Matsukawa, A.4
-
33
-
-
0032827327
-
9-cis retinoic acid induces monocyte chemoattractant protein-1 secretion in human monocytic THP-1 cells
-
Zhu L, Bisgaier CL, Aviram M, Newton RS (1999) 9-cis retinoic acid induces monocyte chemoattractant protein-1 secretion in human monocytic THP-1 cells. Arterioscler Thromb Vasc Biol 19:2105-2111.
-
(1999)
Arterioscler Thromb Vasc Biol
, vol.19
, pp. 2105-2111
-
-
Zhu, L.1
Bisgaier, C.L.2
Aviram, M.3
Newton, R.S.4
-
34
-
-
33947103526
-
RXR: From partnership to leadership in metabolic regulations
-
Desvergne B (2007) RXR: From partnership to leadership in metabolic regulations. Vitam Horm 75:1-32.
-
(2007)
Vitam Horm
, vol.75
, pp. 1-32
-
-
Desvergne, B.1
-
35
-
-
0028096213
-
The directly repeated RG(G/T)TCA motifs of the rat and mouse cellular retinol-binding protein II genes are promiscuous binding sites for RAR, RXR, HNF-4, and ARP-1 homo- and heterodimers
-
Nakshatri H, Chambon P (1994) The directly repeated RG(G/T)TCA motifs of the rat and mouse cellular retinol-binding protein II genes are promiscuous binding sites for RAR, RXR, HNF-4, and ARP-1 homo- and heterodimers. J Biol Chem 269:890-902.
-
(1994)
J Biol Chem
, vol.269
, pp. 890-902
-
-
Nakshatri, H.1
Chambon, P.2
-
36
-
-
0031886864
-
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
-
Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK (1998) The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation. Nature 391:79-82.
-
(1998)
Nature
, vol.391
, pp. 79-82
-
-
Ricote, M.1
Li, A.C.2
Willson, T.M.3
Kelly, C.J.4
Glass, C.K.5
-
37
-
-
0033595261
-
Interleukin-4-dependent production of PPAR-γ ligands in macrophages by 12/15-lipoxygenase
-
Huang JT, et al. (1999) Interleukin-4-dependent production of PPAR-γ ligands in macrophages by 12/15-lipoxygenase. Nature 400:378-382.
-
(1999)
Nature
, vol.400
, pp. 378-382
-
-
Huang, J.T.1
-
39
-
-
9144265739
-
CCR1 and CC chemokine ligand 5 interactions exacerbate innate immune responses during sepsis
-
Ness TL, et al. (2004) CCR1 and CC chemokine ligand 5 interactions exacerbate innate immune responses during sepsis. J Immunol 173:6938-6948.
-
(2004)
J Immunol
, vol.173
, pp. 6938-6948
-
-
Ness, T.L.1
-
40
-
-
0028920237
-
Endogenous distribution of retinoids during normal development and teratogenesis in the mouse embryo
-
Horton C, Maden M (1995) Endogenous distribution of retinoids during normal development and teratogenesis in the mouse embryo. Dev Dyn 202:312-323.
-
(1995)
Dev Dyn
, vol.202
, pp. 312-323
-
-
Horton, C.1
Maden, M.2
-
42
-
-
18544367029
-
Membrane type 1-matrix metalloproteinase is involved in migration of human monocytes and is regulated through their interaction with fibronectin or endothelium
-
Matías-Román S, et al. (2005) Membrane type 1-matrix metalloproteinase is involved in migration of human monocytes and is regulated through their interaction with fibronectin or endothelium. Blood 105:3956-3964.
-
(2005)
Blood
, vol.105
, pp. 3956-3964
-
-
Matías-Román, S.1
|