메뉴 건너뛰기




Volumn 145, Issue 19, 2018, Pages

Deriving functional human enteroendocrine cells from pluripotent stem cells

Author keywords

Hormones; Incretin; Neurogenin 3; Organoids; Satiety; Stem cell

Indexed keywords

GASTRIC INHIBITORY POLYPEPTIDE; GHRELIN; GLUCAGON LIKE PEPTIDE 1; MESSENGER RNA; MOTILIN; NEUROGENIN 3; NEUROTENSIN; OXYNTOMODULIN; SECRETIN; SEROTONIN; SOMATOSTATIN; SUBSTANCE P; VASOACTIVE INTESTINAL POLYPEPTIDE; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; HORMONE; NERVE PROTEIN; NEUROG3 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

EID: 85054097973     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.165795     Document Type: Article
Times cited : (33)

References (58)
  • 1
    • 85008153076 scopus 로고    scopus 로고
    • Induced quiescence of Lgr5+ stem cells in intestinal organoids enables differentiation of hormone-producing enteroendocrine cells
    • Basak, O., Beumer, J., Wiebrands, K., Seno, H., van Oudenaarden, A. and Clevers, H. (2017). Induced quiescence of Lgr5+ stem cells in intestinal organoids enables differentiation of hormone-producing enteroendocrine cells. Cell Stem Cell 20, 177-190.e4.
    • (2017) Cell Stem Cell , vol.20 , pp. 177-190
    • Basak, O.1    Beumer, J.2    Wiebrands, K.3    Seno, H.4    van Oudenaarden, A.5    Clevers, H.6
  • 2
    • 84860536527 scopus 로고    scopus 로고
    • The homeodomain-containing transcription factors Arx and Pax4 control enteroendocrine subtype specification in mice
    • Beucher, A., Gjernes, E., Collin, C., Courtney, M., Meunier, A., Collombat, P. and Gradwohl, G. (2012). The homeodomain-containing transcription factors Arx and Pax4 control enteroendocrine subtype specification in mice. PLoS ONE 7, e36449.
    • (2012) Plos ONE , vol.7
    • Beucher, A.1    Gjernes, E.2    Collin, C.3    Courtney, M.4    Meunier, A.5    Collombat, P.6    Gradwohl, G.7
  • 3
    • 0037510003 scopus 로고    scopus 로고
    • Aberrant regulation of human intestinal proglucagon gene expression in the NCI-H716 cell line
    • Cao, X., Flock, G., Choi, C., Irwin, D. M. and Drucker, D. J. (2003). Aberrant regulation of human intestinal proglucagon gene expression in the NCI-H716 cell line. Endocrinology 144, 2025-2033.
    • (2003) Endocrinology , vol.144 , pp. 2025-2033
    • Cao, X.1    Flock, G.2    Choi, C.3    Irwin, D.M.4    Drucker, D.J.5
  • 4
    • 72749102467 scopus 로고    scopus 로고
    • Pdx1 inactivation restricted to the intestinal epithelium in mice alters duodenal gene expression in enterocytes and enteroendocrine cells
    • Chen, C., Fang, R., Davis, C., Maravelias, C. and Sibley, E. (2009). Pdx1 inactivation restricted to the intestinal epithelium in mice alters duodenal gene expression in enterocytes and enteroendocrine cells. Am. J. Physiol. Gastrointest. Liver Physiol. 297, G1126-G1137.
    • (2009) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.297 , pp. G1126-G1137
    • Chen, C.1    Fang, R.2    Davis, C.3    Maravelias, C.4    Sibley, E.5
  • 6
    • 0028575660 scopus 로고
    • Activation of proglucagon gene transcription by protein kinase-A in a novel mouse enteroendocrine cell line
    • Drucker, D. J., Jin, T., Asa, S. L., Young, T. A. and Brubaker, P. L. (1994). Activation of proglucagon gene transcription by protein kinase-A in a novel mouse enteroendocrine cell line. Mol. Endocrinol. 8, 1646-1655.
    • (1994) Mol. Endocrinol. , vol.8 , pp. 1646-1655
    • Drucker, D.J.1    Jin, T.2    Asa, S.L.3    Young, T.A.4    Brubaker, P.L.5
  • 11
    • 85021745441 scopus 로고    scopus 로고
    • Costorage of enteroendocrine hormones evaluated at the cell and subcellular levels in male mice
    • Fothergill, L. J., Callaghan, B., Hunne, B., Bravo, D. M. and Furness, J. B. (2017). Costorage of enteroendocrine hormones evaluated at the cell and subcellular levels in male mice. Endocrinology 158, 2113-2123.
    • (2017) Endocrinology , vol.158 , pp. 2113-2123
    • Fothergill, L.J.1    Callaghan, B.2    Hunne, B.3    Bravo, D.M.4    Furness, J.B.5
  • 12
  • 13
    • 79951590737 scopus 로고    scopus 로고
    • Neurogenin3 initiates stepwise delamination of differentiating endocrine cells during pancreas development
    • Gouzi, M., Kim, Y. H., Katsumoto, K., Johansson, K. and Grapin-Botton, A. (2011). Neurogenin3 initiates stepwise delamination of differentiating endocrine cells during pancreas development. Dev. Dyn. 240, 589-604.
    • (2011) Dev. Dyn. , vol.240 , pp. 589-604
    • Gouzi, M.1    Kim, Y.H.2    Katsumoto, K.3    Johansson, K.4    Grapin-Botton, A.5
  • 14
    • 0034652287 scopus 로고    scopus 로고
    • Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas
    • Gradwohl, G., Dierich, A., LeMeur, M. and Guillemot, F. (2000). neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc. Natl. Acad. Sci. USA 97, 1607-1611.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 1607-1611
    • Gradwohl, G.1    Dierich, A.2    Lemeur, M.3    Guillemot, F.4
  • 15
    • 0035112448 scopus 로고    scopus 로고
    • Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genes
    • Grapin-Botton, A., Majithia, A. R. and Melton, D. A. (2001). Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genes. Genes Dev. 15, 444-454.
    • (2001) Genes Dev , vol.15 , pp. 444-454
    • Grapin-Botton, A.1    Majithia, A.R.2    Melton, D.A.3
  • 16
    • 79959911030 scopus 로고    scopus 로고
    • Classification and functions of enteroendocrine cells of the lower gastrointestinal tract
    • Gunawardene, A. R., Corfe, B. M. and Staton, C. A. (2011). Classification and functions of enteroendocrine cells of the lower gastrointestinal tract. Int. J. Exp. Pathol. 92, 219-231.
    • (2011) Int. J. Exp. Pathol. , vol.92 , pp. 219-231
    • Gunawardene, A.R.1    Corfe, B.M.2    Staton, C.A.3
  • 17
    • 74749106445 scopus 로고    scopus 로고
    • Stepwise loss of motilin and its specific receptor genes in rodents
    • He, J., Irwin, D. M., Chen, R. and Zhang, Y.-P. (2010). Stepwise loss of motilin and its specific receptor genes in rodents. J. Mol. Endocrinol. 44, 37-44.
    • (2010) J. Mol. Endocrinol. , vol.44 , pp. 37-44
    • He, J.1    Irwin, D.M.2    Chen, R.3    Zhang, Y.-P.4
  • 18
    • 0033996527 scopus 로고    scopus 로고
    • Regulation of the pancreatic islet-specific gene BETA2 (NeuroD) by neurogenin 3
    • Huang, H.-P., Liu, M., El-Hodiri, H. M., Chu, K., Jamrich, M. and Tsai, M.-J. (2000). Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3. Mol. Cell. Biol. 20, 3292-3307.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 3292-3307
    • Huang, H.-P.1    Liu, M.2    El-Hodiri, H.M.3    Chu, K.4    Jamrich, M.5    Tsai, M.-J.6
  • 19
    • 0037011171 scopus 로고    scopus 로고
    • Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium
    • Jenny, M., Uhl, C., Roche, C., Duluc, I., Guillermin, V., Guillemot, F., Jensen, J., Kedinger, M. and Gradwohl, G. (2002). Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium. EMBO J. 21, 6338-6347.
    • (2002) EMBO J , vol.21 , pp. 6338-6347
    • Jenny, M.1    Uhl, C.2    Roche, C.3    Duluc, I.4    Guillermin, V.5    Guillemot, F.6    Jensen, J.7    Kedinger, M.8    Gradwohl, G.9
  • 21
    • 84959108917 scopus 로고    scopus 로고
    • GATA4 regulates epithelial cell proliferation to control intestinal growth and development in mice
    • Kohlnhofer, B. M., Thompson, C. A., Walker, E. M. and Battle, M. A. (2016). GATA4 regulates epithelial cell proliferation to control intestinal growth and development in mice. Cell. Mol. Gastroenterol. Hepatol. 2, 189-209.
    • (2016) Cell. Mol. Gastroenterol. Hepatol. , vol.2 , pp. 189-209
    • Kohlnhofer, B.M.1    Thompson, C.A.2    Walker, E.M.3    Battle, M.A.4
  • 24
    • 79951675071 scopus 로고    scopus 로고
    • Selected tetrapeptides lead to a GLP-1 release from the human enteroendocrine cell line NCI-H716
    • Le Neve, B. and Daniel, H. (2011). Selected tetrapeptides lead to a GLP-1 release from the human enteroendocrine cell line NCI-H716. Regul. Pept. 167, 14-20.
    • (2011) Regul. Pept. , vol.167 , pp. 14-20
    • Le Neve, B.1    Daniel, H.2
  • 25
    • 34548389338 scopus 로고    scopus 로고
    • Intestinal Neurogenin 3 directs differentiation of a bipotential secretory progenitor to endocrine cell rather than goblet cell fate
    • Loṕez-Dıáz, L., Jain, R. N., Keeley, T. M., VanDussen, K. L., Brunkan, C. S., Gumucio, D. L. and Samuelson, L. C. (2007). Intestinal Neurogenin 3 directs differentiation of a bipotential secretory progenitor to endocrine cell rather than goblet cell fate. Dev. Biol. 309, 298-305.
    • (2007) Dev. Biol. , vol.309 , pp. 298-305
    • Loṕez-Dıáz, L.1    Jain, R.N.2    Keeley, T.M.3    Vandussen, K.L.4    Brunkan, C.S.5    Gumucio, D.L.6    Samuelson, L.C.7
  • 26
    • 84941242479 scopus 로고    scopus 로고
    • Establishment of human epithelial enteroids and colonoids from whole tissue and biopsy
    • Mahe, M. M., Sundaram, N., Watson, C. L., Shroyer, N. F. and Helmrath, M. A. (2015). Establishment of human epithelial enteroids and colonoids from whole tissue and biopsy. J. Vis. Exp. 97, e52483.
    • (2015) J. Vis. Exp. , Issue.97
    • Mahe, M.M.1    Sundaram, N.2    Watson, C.L.3    Shroyer, N.F.4    Helmrath, M.A.5
  • 27
    • 84865609719 scopus 로고    scopus 로고
    • Nutrient-mediated modulation of incretin gene expression: A systematic review
    • Martıńez-Rodrıǵuez, R. and Gil, A. (2012). Nutrient-mediated modulation of incretin gene expression: a systematic review. Nutr. Hosp. 27, 46-53.
    • (2012) Nutr. Hosp. , vol.27 , pp. 46-53
    • Martıńez-Rodrıǵuez, R.1    Gil, A.2
  • 29
    • 84942150192 scopus 로고    scopus 로고
    • The basic helix-loop-helix transcription factor NEUROG3 is required for development of the human endocrine pancreas
    • McGrath, P. S., Watson, C. L., Ingram, C., Helmrath, M. A. and Wells, J. M. (2015). The basic helix-loop-helix transcription factor NEUROG3 is required for development of the human endocrine pancreas. Diabetes 64, 2497-2505.
    • (2015) Diabetes , vol.64 , pp. 2497-2505
    • McGrath, P.S.1    Watson, C.L.2    Ingram, C.3    Helmrath, M.A.4    Wells, J.M.5
  • 30
    • 0032533994 scopus 로고    scopus 로고
    • Fatty acids stimulate cholecystokinin secretion via an acyl chain length-specific, Ca2+-dependent mechanism in the enteroendocrine cell line STC-1
    • McLaughlin, J. T., Lomax, R. B., Hall, L., Dockray, G. J., Thompson, D. G. and Warhurst, G. (1998). Fatty acids stimulate cholecystokinin secretion via an acyl chain length-specific, Ca2+-dependent mechanism in the enteroendocrine cell line STC-1. J. Physiol. 513, 11-18.
    • (1998) J. Physiol. , vol.513 , pp. 11-18
    • McLaughlin, J.T.1    Lomax, R.B.2    Hall, L.3    Dockray, G.J.4    Thompson, D.G.5    Warhurst, G.6
  • 31
    • 84862262750 scopus 로고    scopus 로고
    • Diet: Friend or foe of enteroendocrine cells: How it interacts with enteroendocrine cells
    • Moran-Ramos, S., Tovar, A. R. and Torres, N. (2012). Diet: friend or foe of enteroendocrine cells: how it interacts with enteroendocrine cells. Adv. Nutr. 3, 8-20.
    • (2012) Adv. Nutr. , vol.3 , pp. 8-20
    • Moran-Ramos, S.1    Tovar, A.R.2    Torres, N.3
  • 32
    • 0037784011 scopus 로고    scopus 로고
    • GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine
    • Mortensen, K., Christensen, L. L., Holst, J. J. and Orskov, C. (2003). GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine. Regul. Pept. 114, 189-196.
    • (2003) Regul. Pept. , vol.114 , pp. 189-196
    • Mortensen, K.1    Christensen, L.L.2    Holst, J.J.3    Orskov, C.4
  • 35
    • 80455176842 scopus 로고    scopus 로고
    • Intestinal development and differentiation
    • Noah, T. K., Donahue, B. and Shroyer, N. F. (2011). Intestinal development and differentiation. Exp. Cell Res. 317, 2702-2710.
    • (2011) Exp. Cell Res. , vol.317 , pp. 2702-2710
    • Noah, T.K.1    Donahue, B.2    Shroyer, N.F.3
  • 36
    • 77953726006 scopus 로고    scopus 로고
    • The neurohormonal regulation of energy intake in relation to bariatric surgery for obesity
    • Ochner, C. N., Gibson, C., Carnell, S., Dambkowski, C. and Geliebter, A. (2010). The neurohormonal regulation of energy intake in relation to bariatric surgery for obesity. Physiol. Behav. 100, 549-559.
    • (2010) Physiol. Behav. , vol.100 , pp. 549-559
    • Ochner, C.N.1    Gibson, C.2    Carnell, S.3    Dambkowski, C.4    Geliebter, A.5
  • 39
    • 79951648873 scopus 로고    scopus 로고
    • Pancreas organogenesis: From bud to plexus to gland
    • Pan, F. C. and Wright, C. (2011). Pancreas organogenesis: from bud to plexus to gland. Dev. Dyn. 240, 530-565.
    • (2011) Dev. Dyn. , vol.240 , pp. 530-565
    • Pan, F.C.1    Wright, C.2
  • 40
    • 84924250999 scopus 로고    scopus 로고
    • Regulation of appetite, satiation, and body weight by enteroendocrine cells. Part 1: Characteristics of enteroendocrine cells and their capability of weight regulation
    • Posovszky, C. and Wabitsch, M. (2015). Regulation of appetite, satiation, and body weight by enteroendocrine cells. Part 1: characteristics of enteroendocrine cells and their capability of weight regulation. Horm. Res. Paediatr. 83, 1-10.
    • (2015) Horm. Res. Paediatr. , vol.83 , pp. 1-10
    • Posovszky, C.1    Wabitsch, M.2
  • 43
    • 0032841609 scopus 로고    scopus 로고
    • Targeted ablation of secretin-producing cells in transgenic mice reveals a common differentiation pathway with multiple enteroendocrine cell lineages in the small intestine
    • Rindi, G., Ratineau, C., Ronco, A., Candusso, M. E., Tsai, M. and Leiter, A. B. (1999). Targeted ablation of secretin-producing cells in transgenic mice reveals a common differentiation pathway with multiple enteroendocrine cell lineages in the small intestine. Development 126, 4149-4156.
    • (1999) Development , vol.126 , pp. 4149-4156
    • Rindi, G.1    Ratineau, C.2    Ronco, A.3    Candusso, M.E.4    Tsai, M.5    Leiter, A.B.6
  • 45
    • 79959778996 scopus 로고    scopus 로고
    • The translational value of rodent gastrointestinal functions: A cautionary tale
    • Sanger, G. J., Holbrook, J. D. and Andrews, P. L. R. (2011). The translational value of rodent gastrointestinal functions: a cautionary tale. Trends Pharmacol. Sci. 32, 402-409.
    • (2011) Trends Pharmacol. Sci. , vol.32 , pp. 402-409
    • Sanger, G.J.1    Holbrook, J.D.2    Andrews, P.L.R.3
  • 47
    • 34249987090 scopus 로고    scopus 로고
    • Intestine-specific ablation of mouse atonal homolog 1 (Math1) reveals a role in cellular homeostasis
    • Shroyer, N. F., Helmrath, M. A., Wang, V. Y.-C., Antalffy, B., Henning, S. J. and Zoghbi, H. Y. (2007). Intestine-specific ablation of mouse atonal homolog 1 (Math1) reveals a role in cellular homeostasis. Gastroenterology 132, 2478-2488.
    • (2007) Gastroenterology , vol.132 , pp. 2478-2488
    • Shroyer, N.F.1    Helmrath, M.A.2    Wang, V.Y.-C.3    Antalffy, B.4    Henning, S.J.5    Zoghbi, H.Y.6
  • 48
    • 0020501561 scopus 로고
    • Endocrine cells in human intestine: An immunocytochemical study
    • Sjolund, K., Sanden, G., Hakanson, R. and Sundler, F. (1983). Endocrine cells in human intestine: an immunocytochemical study. Gastroenterology 85, 1120-1130.
    • (1983) Gastroenterology , vol.85 , pp. 1120-1130
    • Sjolund, K.1    Sanden, G.2    Hakanson, R.3    Sundler, F.4
  • 49
    • 0141643340 scopus 로고    scopus 로고
    • Neurogenin3 and hepatic nuclear factor 1 cooperate in activating pancreatic expression of Pax4
    • Smith, S. B., Gasa, R., Watada, H., Wang, J., Griffen, S. C. and German, M. S. (2003). Neurogenin3 and hepatic nuclear factor 1 cooperate in activating pancreatic expression of Pax4. J. Biol. Chem. 278, 38254-38259.
    • (2003) J. Biol. Chem. , vol.278 , pp. 38254-38259
    • Smith, S.B.1    Gasa, R.2    Watada, H.3    Wang, J.4    Griffen, S.C.5    German, M.S.6
  • 50
    • 0346024328 scopus 로고    scopus 로고
    • Neurogenin3 activates the islet differentiation program while repressing its own expression
    • Smith, S. B., Watada, H. and German, M. S. (2004). Neurogenin3 activates the islet differentiation program while repressing its own expression. Mol. Endocrinol. 18, 142-149.
    • (2004) Mol. Endocrinol. , vol.18 , pp. 142-149
    • Smith, S.B.1    Watada, H.2    German, M.S.3
  • 53
    • 85007298368 scopus 로고    scopus 로고
    • Ghrelin, CCK, GLP-1, and PYY(3–36): Secretory controls and physiological roles in eating and glycemia in health, obesity, and after RYGB
    • Steinert, R. E., Feinle-Bisset, C., Asarian, L., Horowitz, M., Beglinger, C. and Geary, N. (2017). Ghrelin, CCK, GLP-1, and PYY(3–36): secretory controls and physiological roles in eating and glycemia in health, obesity, and after RYGB. Physiol. Rev. 97, 411-463.
    • (2017) Physiol. Rev. , vol.97 , pp. 411-463
    • Steinert, R.E.1    Feinle-Bisset, C.2    Asarian, L.3    Horowitz, M.4    Beglinger, C.5    Geary, N.6
  • 55
    • 79957780140 scopus 로고    scopus 로고
    • Dual-monoclonal, sandwich immunoassay specific for glucose-dependent insulinotropic peptide1-42, the active form of the incretin hormone
    • Troutt, J. S., Siegel, R. W., Chen, J., Sloan, J. H., Deeg, M. A., Cao, G. and Konrad, R. J. (2011). Dual-monoclonal, sandwich immunoassay specific for glucose-dependent insulinotropic peptide1-42, the active form of the incretin hormone. Clin. Chem. 57, 849-855.
    • (2011) Clin. Chem. , vol.57 , pp. 849-855
    • Troutt, J.S.1    Siegel, R.W.2    Chen, J.3    Sloan, J.H.4    Deeg, M.A.5    Cao, G.6    Konrad, R.J.7
  • 56
    • 0037931806 scopus 로고    scopus 로고
    • Distinct gene expression programs function in progenitor and mature islet cells
    • Watada, H., Scheel, D. W., Leung, J. and German, M. S. (2003). Distinct gene expression programs function in progenitor and mature islet cells. J. Biol. Chem. 278, 17130-17140.
    • (2003) J. Biol. Chem. , vol.278 , pp. 17130-17140
    • Watada, H.1    Scheel, D.W.2    Leung, J.3    German, M.S.4
  • 58
    • 0035824487 scopus 로고    scopus 로고
    • Requirement of Math1 for secretory cell lineage commitment in the mouse intestine
    • Yang, Q., Bermingham, N. A., Finegold, M. J. and Zoghbi, H. Y. (2001). Requirement of Math1 for secretory cell lineage commitment in the mouse intestine. Science 294, 2155-2158.
    • (2001) Science , vol.294 , pp. 2155-2158
    • Yang, Q.1    Bermingham, N.A.2    Finegold, M.J.3    Zoghbi, H.Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.