메뉴 건너뛰기




Volumn 297, Issue 6, 2009, Pages

Pdx1 inactivation restricted to the intestinal epithelium in mice alters duodenal gene expression in enterocytes and enteroendocrine cells

Author keywords

Anterior posterior patterning; Conditional knockout; Proximal small intestine; Tissue specific

Indexed keywords

ALKALINE PHOSPHATASE; CHROMOGRANIN A; CHROMOGRANIN B; CRE RECOMBINASE; GASTRIC INHIBITORY POLYPEPTIDE; MATRILYSIN; MESSENGER RNA; MUCIN 3; SOMATOSTATIN; TRANSCRIPTION FACTOR PDX 1; VILLIN;

EID: 72749102467     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.90586.2008     Document Type: Article
Times cited : (35)

References (64)
  • 1
    • 0032525981 scopus 로고    scopus 로고
    • Beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes
    • Ahlgren U, Jonsson J, Jonsson L, Simu K, Edlund H. Beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes. Genes Dev 12: 1763-1768, 1998. (Pubitemid 28304328)
    • (1998) Genes and Development , vol.12 , Issue.12 , pp. 1763-1768
    • Ahlgren, U.1    Jonsson, J.2    Jonsson, L.3    Simu, K.4    Edlund, H.5
  • 2
    • 0032982022 scopus 로고    scopus 로고
    • Pax6 and Pdx1 form a functional complex on the rat somatostatin gene upstream enhancer
    • DOI 10.1016/S0014-5793(99)00144-1, PII S0014579399001441
    • Andersen FG, Jensen J, Heller RS, Petersen HV, Larsson LI, Madsen OD, Serup P. Pax6 and Pdx1 form a functional complex on the rat somatostatin gene upstream enhancer. FEBS Lett 445: 315-320, 1999. (Pubitemid 29117235)
    • (1999) FEBS Letters , vol.445 , Issue.2-3 , pp. 315-320
    • Andersen, F.G.1    Jensen, J.2    Heller, R.S.3    Petersen, H.V.4    Larsson, L.-I.5    Madsen, O.D.6    Serup, P.7
  • 3
    • 0033506651 scopus 로고    scopus 로고
    • Pbx-Hox heterodimers recruit coactivator-corepressor complexes in an isoform-specific manner
    • Asahara H, Dutta S, Kao HY, Evans RM, Montminy M. Pbx-Hox heterodimers recruit coactivator-corepressor complexes in an isoform-specific manner. Mol Cell Biol 19: 8219-8225, 1999.
    • (1999) Mol Cell Biol , vol.19 , pp. 8219-8225
    • Asahara, H.1    Dutta, S.2    Kao, H.Y.3    Evans, R.M.4    Montminy, M.5
  • 4
    • 34548418914 scopus 로고    scopus 로고
    • A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis
    • Babu DA, Deering TG, Mirmira RG. A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis. Mol Genet Metab 92: 43-55, 2007.
    • (2007) Mol Genet Metab , vol.92 , pp. 43-55
    • Babu, D.A.1    Deering, T.G.2    Mirmira, R.G.3
  • 5
    • 33748983189 scopus 로고    scopus 로고
    • Complementation rescue of Pdx1 null phenotype demonstrates distinct roles of proximal and distal cis-regulatory sequences in pancreatic and duodenal expression
    • Boyer DF, Fujitani Y, Gannon M, Powers AC, Stein RW, Wright CV. Complementation rescue of Pdx1 null phenotype demonstrates distinct roles of proximal and distal cis-regulatory sequences in pancreatic and duodenal expression. Dev Biol 298: 616-631, 2006.
    • (2006) Dev Biol , vol.298 , pp. 616-631
    • Boyer, D.F.1    Fujitani, Y.2    Gannon, M.3    Powers, A.C.4    Stein, R.W.5    Wright, C.V.6
  • 6
    • 0030065520 scopus 로고    scopus 로고
    • Insulin upstream factor 1 and a novel ubiquitous factor bind to the human islet amyloid polypeptide/amylin gene promoter
    • Bretherton-Watt D, Gore N, Boam DS. Insulin upstream factor 1 and a novel ubiquitous factor bind to the human islet amyloid polypeptide/amylin gene promoter. Biochem J 313: 495-502, 1996.
    • (1996) Biochem J , vol.313 , pp. 495-502
    • Bretherton-Watt, D.1    Gore, N.2    Boam, D.S.3
  • 7
    • 2642713364 scopus 로고    scopus 로고
    • The ParaHox gene cluster is an evolutionary sister of the Hox gene cluster
    • Brooke NM, Garcia-Fernandez J, Holland PW. The ParaHox gene cluster is an evolutionary sister of the Hox gene cluster. Nature 392: 920-922, 1998.
    • (1998) Nature , vol.392 , pp. 920-922
    • Brooke, N.M.1    Garcia-Fernandez, J.2    Holland, P.W.3
  • 8
    • 0018193765 scopus 로고
    • Electronimmunocytochemical evidence for the K cell localization of gastric inhibitory polypeptide (GIP) in man
    • Buchan AM, Polak JM, Capella C, Solcia E, Pearse AG. Electron immunocytochemical evidence for the K cell localization of gastric inhibitory polypeptide (GIP) in man. Histochemistry 56: 37-44, 1978. (Pubitemid 8356098)
    • (1978) Histochemistry , vol.56 , Issue.1 , pp. 37-44
    • Buchan, A.M.J.1    Polak, J.M.2    Capella, C.3
  • 9
    • 0031007661 scopus 로고    scopus 로고
    • Identification of cis- and trans-active factors regulating human islet amyloid polypeptide gene expression in pancreatic beta-cells
    • Carty MD, Lillquist JS, Peshavaria M, Stein R, Soeller WC. Identification of cis- and trans-active factors regulating human islet amyloid polypeptide gene expression in pancreatic beta-cells. J Biol Chem 272: 11986-11993, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 11986-11993
    • Carty, M.D.1    Lillquist, J.S.2    Peshavaria, M.3    Stein, R.4    Soeller, W.C.5
  • 10
    • 1942469471 scopus 로고    scopus 로고
    • PDX1, a cellular homeoprotein, binds to and regulates the activity of human cytomegalovirus immediate early promoter
    • Chao SH, Harada JN, Hyndman F, Gao X, Nelson CG, Chanda SK, Caldwell JS. PDX1, a cellular homeoprotein, binds to and regulates the activity of human cytomegalovirus immediate early promoter. J Biol Chem 279: 16111-16120, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 16111-16120
    • Chao, S.H.1    Harada, J.N.2    Hyndman, F.3    Gao, X.4    Nelson, C.G.5    Chanda, S.K.6    Caldwell, J.S.7
  • 12
    • 0035957940 scopus 로고    scopus 로고
    • Pdx-1 is required for activation in vivo from a duodenum-specific enhancer
    • Dusing MR, Florence EA, Wiginton DA. Pdx-1 is required for activation in vivo from a duodenum-specific enhancer. J Biol Chem 276: 14434-14442, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 14434-14442
    • Dusing, M.R.1    Florence, E.A.2    Wiginton, D.A.3
  • 13
    • 0027507568 scopus 로고
    • Murine Cdx-4 bears striking similarities to the Drosophila caudal gene in its homeodomain sequence and early expression pattern
    • Gamer LW, Wright CV. Murine Cdx-4 bears striking similarities to the Drosophila caudal gene in its homeodomain sequence and early expression pattern. Mech Dev 43: 71-81, 1993.
    • (1993) Mech Dev , vol.43 , pp. 71-81
    • Gamer, L.W.1    Wright, C.V.2
  • 14
    • 38949149704 scopus 로고    scopus 로고
    • Pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis
    • Gannon M, Ables ET, Crawford L, Lowe D, Offield MF, Magnuson MA, Wright CV. Pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis. Dev Biol 314: 406-417, 2008.
    • (2008) Dev Biol , vol.314 , pp. 406-417
    • Gannon, M.1    Ables, E.T.2    Crawford, L.3    Lowe, D.4    Offield, M.F.5    Magnuson, M.A.6    Wright, C.V.7
  • 15
    • 0014960299 scopus 로고
    • Increased lymph alkaline phosphatase after fat feeding: Effects of medium chain triglycerides and inhibition of protein synthesis
    • Glickman RM, Alpers DH, Drummey GD, Isselbacher KJ. Increased lymph alkaline phosphatase after fat feeding: effects of medium chain triglycerides and inhibition of protein synthesis. Biochim Biophys Acta 201: 226-235, 1970.
    • (1970) Biochim Biophys Acta , vol.201 , pp. 226-235
    • Glickman, R.M.1    Alpers, D.H.2    Drummey, G.D.3    Isselbacher, K.J.4
  • 17
    • 0033548195 scopus 로고    scopus 로고
    • Functional and cooperative interactions between the homeodomain PDX1, Pbx, and Prep1 factors on the somatostatin promoter
    • Goudet G, Delhalle S, Biemar F, Martial JA, Peers B. Functional and cooperative interactions between the homeodomain PDX1, Pbx, and Prep1 factors on the somatostatin promoter. J Biol Chem 274: 4067-4073, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 4067-4073
    • Goudet, G.1    Delhalle, S.2    Biemar, F.3    Martial, J.A.4    Peers, B.5
  • 18
    • 0028869514 scopus 로고
    • Expression of murine STF-1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny
    • Guz Y, Montminy MR, Stein R, Leonard J, Gamer LW, Wright CV, Teitelman G. Expression of murine STF-1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny. Development 121: 11-18, 1995.
    • (1995) Development , vol.121 , pp. 11-18
    • Guz, Y.1    Montminy, M.R.2    Stein, R.3    Leonard, J.4    Gamer, L.W.5    Wright, C.V.6    Teitelman, G.7
  • 19
    • 0031904172 scopus 로고    scopus 로고
    • Misexpression of the pancreatic homeodomain protein IDX-1 by the Hoxa-4 promoter associated with agenesis of the cecum
    • Heller RS, Stoffers DA, Hussain MA, Miller CP, Habener JF. Misexpression of the pancreatic homeodomain protein IDX-1 by the Hoxa-4 promoter associated with agenesis of the cecum. Gastroenterology 115: 381-387, 1998.
    • (1998) Gastroenterology , vol.115 , pp. 381-387
    • Heller, R.S.1    Stoffers, D.A.2    Hussain, M.A.3    Miller, C.P.4    Habener, J.F.5
  • 20
    • 0015676776 scopus 로고
    • Interspecific variation in the levels of intestinal alkaline phosphatase, adenosine triphosphatase and disaccharidases
    • Hietanen E. Interspecific variation in the levels of intestinal alkaline phosphatase, adenosine triphosphatase and disaccharidases. Comp Biochem Physiol A 46: 359-369, 1973.
    • (1973) Comp Biochem Physiol A , vol.46 , pp. 359-369
    • Hietanen, E.1
  • 21
    • 0037011171 scopus 로고    scopus 로고
    • Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium
    • Jenny M, Uhl C, Roche C, Duluc I, Guillermin V, Guillemot F, Jensen J, Kedinger M, Gradwohl G. Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium. EMBO J 21: 6338-6347, 2002.
    • (2002) EMBO J , vol.21 , pp. 6338-6347
    • Jenny, M.1    Uhl, C.2    Roche, C.3    Duluc, I.4    Guillermin, V.5    Guillemot, F.6    Jensen, J.7    Kedinger, M.8    Gradwohl, G.9
  • 22
    • 11144230786 scopus 로고    scopus 로고
    • Cell-specific expression of glucose-dependent-insulinotropic polypeptide is regulated by the transcription factor PDX-1
    • DOI 10.1210/en.2004-0223
    • Jepeal LI, Fujitani Y, Boylan MO, Wilson CN, Wright CV, Wolfe MM. Cell-specific expression of glucose-dependent-insulinotropic polypeptide is regulated by the transcription factor PDX-1. Endocrinology 146: 383-391, 2005. (Pubitemid 40051762)
    • (2005) Endocrinology , vol.146 , Issue.1 , pp. 383-391
    • Jepeal, L.I.1    Fujitani, Y.2    Boylan, M.O.3    Wilson, C.N.4    Wright, C.V.5    Wolfe, M.M.6
  • 23
    • 0028149890 scopus 로고
    • Insulin-promoter-factor 1 is required for pancreas development in mice
    • Jonsson J, Carlsson L, Edlund T, Edlund H. Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 371: 606-609, 1994.
    • (1994) Nature , vol.371 , pp. 606-609
    • Jonsson, J.1    Carlsson, L.2    Edlund, T.3    Edlund, H.4
  • 24
    • 0030448129 scopus 로고    scopus 로고
    • Pancreatic-duodenal homeobox 1 -role in gastric endocrine patterning
    • Larsson LI, Madsen OD, Serup P, Jonsson J, Edlund H. Pancreatic-duodenal homeobox 1 -role in gastric endocrine patterning. Mech Dev 60: 175-184, 1996.
    • (1996) Mech Dev , vol.60 , pp. 175-184
    • Larsson, L.I.1    Madsen, O.D.2    Serup, P.3    Jonsson, J.4    Edlund, H.5
  • 25
    • 0037066758 scopus 로고    scopus 로고
    • Regulation of intestine-specific spatiotemporal expression by the rat lactase promoter
    • Lee SY, Wang Z, Lin CK, Contag CH, Olds LC, Cooper AD, Sibley E. Regulation of intestine-specific spatiotemporal expression by the rat lactase promoter. J Biol Chem 277: 13099-13105, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 13099-13105
    • Lee, S.Y.1    Wang, Z.2    Lin, C.K.3    Contag, C.H.4    Olds, L.C.5    Cooper, A.D.6    Sibley, E.7
  • 26
    • 0027373441 scopus 로고
    • Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells
    • Leonard J, Peers B, Johnson T, Ferreri K, Lee S, Montminy MR. Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells. Mol Endocrinol 7: 1275-1283, 1993.
    • (1993) Mol Endocrinol , vol.7 , pp. 1275-1283
    • Leonard, J.1    Peers, B.2    Johnson, T.3    Ferreri, K.4    Lee, S.5    Montminy, M.R.6
  • 27
    • 0026628841 scopus 로고
    • The LIM family transcription factor Isl-1 requires cAMP response element binding protein to promote somatostatin expression in pancreatic islet cells
    • Leonard J, Serup P, Gonzalez G, Edlund T, Montminy M. The LIM family transcription factor Isl-1 requires cAMP response element binding protein to promote somatostatin expression in pancreatic islet cells. Proc Natl Acad Sci USA 89: 6247-6251, 1992.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 6247-6251
    • Leonard, J.1    Serup, P.2    Gonzalez, G.3    Edlund, T.4    Montminy, M.5
  • 28
    • 0026481214 scopus 로고
    • The defensin-related murine CRS1C gene: Expression in Paneth cells and linkage to Defcr, the cryptdin locus
    • Lin MY, Munshi IA, Ouellette AJ. The defensin-related murine CRS1C gene: expression in Paneth cells and linkage to Defcr, the cryptdin locus. Genomics 14: 363-368, 1992.
    • (1992) Genomics , vol.14 , pp. 363-368
    • Lin, M.Y.1    Munshi, I.A.2    Ouellette, A.J.3
  • 29
    • 0035947656 scopus 로고    scopus 로고
    • DNA Binding and Transcriptional Activation by a PDX1. PBX1b MEIS2b Trimer and Cooperation with a Pancreas-specific Basic Helix-Loop-Helix Complex
    • DOI 10.1074/jbc.M100678200
    • Liu Y, MacDonald RJ, Swift GH. DNA binding and transcriptional activation by a PDX1. PBX1b MEIS2b trimer and cooperation with a pancreas-specific basic helix-loop-helix complex. J Biol Chem 276: 17985-17993, 2001. (Pubitemid 37411360)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.21 , pp. 17985-17993
    • Liu, Y.1    MacDonald, R.J.2    Swift, G.H.3
  • 31
    • 0037031856 scopus 로고    scopus 로고
    • Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine
    • DOI 10.1074/jbc.M204935200
    • Madison BB, Dunbar L, Qiao XT, Braunstein K, Braunstein E, Gumucio DL. Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine. J Biol Chem 277: 33275-33283, 2002. (Pubitemid 34984848)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.36 , pp. 33275-33283
    • Madison, B.B.1    Dunbar, L.2    Qiao, X.T.3    Braunstein, K.4    Braunstein, E.5    Gumucio, D.L.6
  • 35
    • 0020490742 scopus 로고
    • The role of the liver in clearance of glycoproteins from the general circulation, with special reference to intestinal alkaline phosphatase
    • Meijer DK, Scholtens HB, Hardonk MJ. The role of the liver in clearance of glycoproteins from the general circulation, with special reference to intestinal alkaline phosphatase. Pharm Weekbl Sci 4: 57-70, 1982.
    • (1982) Pharm Weekbl Sci , vol.4 , pp. 57-70
    • Meijer, D.K.1    Scholtens, H.B.2    Hardonk, M.J.3
  • 36
    • 0028314969 scopus 로고
    • IDX-1: A new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene
    • Miller CP, McGehee RE Jr, Habener JF. IDX-1: a new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene. EMBO J 13: 1145-1156, 1994.
    • (1994) EMBO J , vol.13 , pp. 1145-1156
    • Miller, C.P.1    McGehee Jr., R.E.2    Habener, J.F.3
  • 42
    • 0027384997 scopus 로고
    • IPF1, a homeodomain-containing transactivator of the insulin gene
    • Ohlsson H, Karlsson K, Edlund T. IPF1, a homeodomain-containing transactivator of the insulin gene. EMBO J 12: 4251-4259, 1993. (Pubitemid 23302039)
    • (1993) EMBO Journal , vol.12 , Issue.11 , pp. 4251-4259
    • Ohlsson, H.1    Karlsson, K.2    Edlund, T.3
  • 43
    • 0028868441 scopus 로고
    • The pancreatic islet factor STF-1 binds cooperatively with Pbx to a regulatory element in the somatostatin promoter: Importance of the FPWMK motif and of the homeodomain
    • Peers B, Sharma S, Johnson T, Kamps M, Montminy M. The pancreatic islet factor STF-1 binds cooperatively with Pbx to a regulatory element in the somatostatin promoter: importance of the FPWMK motif and of the homeodomain. Mol Cell Biol 15: 7091-7097, 1995.
    • (1995) Mol Cell Biol , vol.15 , pp. 7091-7097
    • Peers, B.1    Sharma, S.2    Johnson, T.3    Kamps, M.4    Montminy, M.5
  • 44
    • 0020566632 scopus 로고
    • Distribution and characterisation of immunoreactive somatostatin in human gastrointestinal tract
    • Penman E, Wass JA, Butler MG, Penny ES, Price J, Wu P, Rees LH. Distribution and characterisation of immunoreactive somatostatin in human gastrointestinal tract. Regul Pept 7: 53-65, 1983.
    • (1983) Regul Pept , vol.7 , pp. 53-65
    • Penman, E.1    Wass, J.A.2    Butler, M.G.3    Penny, E.S.4    Price, J.5    Wu, P.6    Rees, L.H.7
  • 45
    • 0034530947 scopus 로고    scopus 로고
    • The PDX-1 activation domain provides specific functions necessary for transcriptional stimulation in pancreatic beta-cells
    • Peshavaria M, Cissell MA, Henderson E, Petersen HV, Stein R. The PDX-1 activation domain provides specific functions necessary for transcriptional stimulation in pancreatic beta-cells. Mol Endocrinol 14: 1907-1917, 2000.
    • (2000) Mol Endocrinol , vol.14 , pp. 1907-1917
    • Peshavaria, M.1    Cissell, M.A.2    Henderson, E.3    Petersen, H.V.4    Stein, R.5
  • 46
    • 0016805689 scopus 로고
    • Growth-hormone release-inhibiting hormone in gastrointestinal and pancreatic D cells
    • Polak JM, Pearse AG, Grimelius L, Bloom SR. Growth-hormone release-inhibiting hormone in gastrointestinal and pancreatic D cells. Lancet 1: 1220-1222, 1975.
    • (1975) Lancet , vol.1 , pp. 1220-1222
    • Polak, J.M.1    Pearse, A.G.2    Grimelius, L.3    Bloom, S.R.4
  • 47
    • 0021105680 scopus 로고
    • Somatostatin
    • Reichlin S. Somatostatin. N Engl J Med 309: 1495-1501, 1983.
    • (1983) N Engl J Med , vol.309 , pp. 1495-1501
    • Reichlin, S.1
  • 49
    • 0027455043 scopus 로고
    • Differential control of somatostatin messenger RNA in rat gastric corpus and antrum. Role of acid, food, and capsaicin-sensitive afferent neurons
    • Sandvik AK, Dimaline R, Forster ER, Evans D, Dockray GJ. Differential control of somatostatin messenger RNA in rat gastric corpus and antrum. Role of acid, food, and capsaicin-sensitive afferent neurons. J Clin Invest 91: 244-250, 1993. (Pubitemid 23037278)
    • (1993) Journal of Clinical Investigation , vol.91 , Issue.1 , pp. 244-250
    • Sandvik, A.K.1    Dimaline, R.2    Forster, E.R.3    Evans, D.4    Dockray, G.J.5
  • 50
    • 0023780022 scopus 로고
    • Development of the pattern of cell renewal in the crypt-villus unit of chimaeric mouse small intestine
    • Schmidt GH, Winton DJ, Ponder BA. Development of the pattern of cell renewal in the crypt-villus unit of chimaeric mouse small intestine. Development 103: 785-790, 1988.
    • (1988) Development , vol.103 , pp. 785-790
    • Schmidt, G.H.1    Winton, D.J.2    Ponder, B.A.3
  • 52
    • 20644462344 scopus 로고    scopus 로고
    • Mammalian defensins in the antimicrobial immune response
    • Selsted ME, Ouellette AJ. Mammalian defensins in the antimicrobial immune response. Nat Immunol 6: 551-557, 2005.
    • (2005) Nat Immunol , vol.6 , pp. 551-557
    • Selsted, M.E.1    Ouellette, A.J.2
  • 54
    • 0026687778 scopus 로고
    • Multiple elements in the upstream glucokinase promoter contribute to transcription in insulinoma cells
    • Shelton KD, Franklin AJ, Khoor A, Beechem J, Magnuson MA. Multiple elements in the upstream glucokinase promoter contribute to transcription in insulinoma cells. Mol Cell Biol 12: 4578-4589, 1992.
    • (1992) Mol Cell Biol , vol.12 , pp. 4578-4589
    • Shelton, K.D.1    Franklin, A.J.2    Khoor, A.3    Beechem, J.4    Magnuson, M.A.5
  • 55
    • 0031813431 scopus 로고    scopus 로고
    • An endocrine-exocrine switch in the activity of the pancreatic homeodomain protein PDX1 through formation of a trimeric complex with PBX1b and MRG1 (MEIS2)
    • Swift GH, Liu Y, Rose SD, Bischof LJ, Steelman S, Buchberg AM, Wright CV, MacDonald RJ. An endocrine-exocrine switch in the activity of the pancreatic homeodomain protein PDX1 through formation of a trimeric complex with PBX1b and MRG1 (MEIS2). Mol Cell Biol 18:5109-5120, 1998. (Pubitemid 28388094)
    • (1998) Molecular and Cellular Biology , vol.18 , Issue.9 , pp. 5109-5120
    • Swift, G.H.1    Liu, Y.2    Rose, S.D.3    Bischof, L.J.4    Steelman, S.5    Buchberg, A.M.6    Wright, C.V.E.7    Macdonald, R.J.8
  • 56
    • 1442284345 scopus 로고    scopus 로고
    • Transcriptional regulation of human SREBP-1c (sterol-regulatory-element- Binding protein-1c): A key regulator of lipogenesis
    • DOI 10.1042/BST0320107
    • Tarling E, Salter A, Bennett A. Transcriptional regulation of human SREBP-1c (sterol-regulatory-element-binding protein-1c): a key regulator of lipogenesis. Biochem Soc Trans 32: 107-109, 2004. (Pubitemid 38283025)
    • (2004) Biochemical Society Transactions , vol.32 , Issue.1 , pp. 107-109
    • Tarling, E.1    Salter, A.2    Bennett, A.3
  • 57
    • 0026723466 scopus 로고
    • Somatostatin gene transcription regulated by a bipartite pancreatic islet D-cell-specific enhancer coupled synergetically to a cAMP response element
    • Vallejo M, Miller CP, Habener JF. Somatostatin gene transcription regulated by a bipartite pancreatic islet D-cell-specific enhancer coupled synergetically to a cAMP response element. J Biol Chem 267: 12868-12875, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 12868-12875
    • Vallejo, M.1    Miller, C.P.2    Habener, J.F.3
  • 58
    • 0030457705 scopus 로고    scopus 로고
    • Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor
    • DOI 10.1210/me.10.11.1327
    • Waeber G, Thompson N, Nicod P, Bonny C. Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor. Mol Endocrinol 10: 1327-1334, 1996. (Pubitemid 26423223)
    • (1996) Molecular Endocrinology , vol.10 , Issue.11 , pp. 1327-1334
    • Waeber, G.1    Thompson, N.2    Nicod, P.3    Bonny, C.4
  • 60
    • 0029909387 scopus 로고    scopus 로고
    • The human glucokinase gene beta-cell-type promoter: An essential role of insulin promoter factor 1/PDX-1 in its activation in HIT-T15 cells
    • Watada H, Kajimoto Y, Umayahara Y, Matsuoka T, Kaneto H, Fujitani Y, Kamada T, Kawamori R, Yamasaki Y. The human glucokinase gene beta-cell-type promoter: an essential role of insulin promoter factor 1/PDX-1 in its activation in HIT-T15 cells. Diabetes 45: 1478-1488, 1996. (Pubitemid 26357538)
    • (1996) Diabetes , vol.45 , Issue.11 , pp. 1478-1488
    • Watada, H.1    Kajimoto, Y.2    Umayahara, Y.3    Matsuoka, T.-A.4    Kaneto, H.5    Fujitani, Y.6    Kamada, T.7    Kawamori, R.8    Yamasaki, Y.9
  • 62
    • 0031048857 scopus 로고    scopus 로고
    • Rat intestinal alkaline phosphatase II messenger RNA is present in duodenal crypt and villus cells
    • DOI 10.1053/gast.1997.v112.pm9024291
    • Xie QM, Zhang Y, Mahmood S, Alpers DH. Rat intestinal alkaline phosphatase II messenger RNA is present in duodenal crypt and villus cells. Gastroenterology 112: 376-386, 1997. (Pubitemid 27078824)
    • (1997) Gastroenterology , vol.112 , Issue.2 , pp. 376-386
    • Xie, Q.-M.1    Zhang, Y.2    Mahmood, S.3    Alpers, D.H.4
  • 64
    • 0030065181 scopus 로고    scopus 로고
    • Immunolocalization of alkaline phosphatase and surfactant-like particle proteins in rat duodenum during fat absorption
    • DOI 10.1053/gast.1996.v110.pm8566595
    • Zhang Y, Shao JS, Xie QM, Alpers DH. Immunolocalization of alkaline phosphatase and surfactant-like particle proteins in rat duodenum during fat absorption. Gastroenterology 110: 478-488, 1996. (Pubitemid 26043881)
    • (1996) Gastroenterology , vol.110 , Issue.2 , pp. 478-488
    • Zhang, Y.1    Shao, J.-S.2    Xie, Q.-M.3    Alpers, D.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.