Estimation of complex effect-size distributions using summary-level statistics from genome-wide association studies across 32 complex traits

Nature Genetics

Volumn 50, Issue 9, 2018, Pages 1318-1326

  Zhang, Yan ^a   Qi, Guanghao ^a   Park, Ju Hyun ^b   Chatterjee, Nilanjan ^a,c  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b Dongguk University   (South Korea)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; APTITUDE; ARTICLE; ASTHMA; AUTISM; AUTOIMMUNE DISEASE; BIPOLAR DISORDER; BODY MASS; CONTROLLED STUDY; CORONARY ARTERY DISEASE; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOME-WIDE ASSOCIATION STUDY; HERITABILITY; HIP CIRCUMFERENCE; HUMAN; INFLAMMATORY BOWEL DISEASE; INTELLIGENCE; MAJOR DEPRESSION; MENTAL DISEASE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; QUANTITATIVE TRAIT; RHEUMATOID ARTHRITIS; SCHIZOPHRENIA; SENSITIVITY ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; ULCERATIVE COLITIS; WAIST CIRCUMFERENCE; BIOLOGICAL MODEL; GENETIC PREDISPOSITION; GENETICS; GENOME; MULTIFACTORIAL INHERITANCE; PHENOTYPE; PROCEDURES; RISK FACTOR; STATISTICAL MODEL;

GENETIC PREDISPOSITION TO DISEASE; GENOME; GENOME-WIDE ASSOCIATION STUDY; HUMANS; LIKELIHOOD FUNCTIONS; LINKAGE DISEQUILIBRIUM; MENTAL DISORDERS; MODELS, GENETIC; MULTIFACTORIAL INHERITANCE; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 85052492980     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/s41588-018-0193-x     Document Type: Article

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