Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

Nature Communications

Volumn 9, Issue 1, 2018, Pages

  Natarajan, Pradeep ^a,b,c   Peloso, Gina M ^d   Zekavat, Seyedeh Maryam ^c,e,f   Montasser, May ^g   Ganna, Andrea ^a,c   Chaffin, Mark ^c   Khera, Amit V ^a,b,c   Zhou, Wei ^h   Bloom, Jonathan M ^a,c   Engreitz, Jesse M ^c,i   Ernst, Jason ^j   O’Connell, Jeffrey R ^g   Ruotsalainen, Sanni E ^k   Alver, Maris ^l   Manichaikul, Ani ^m   Johnson, W Craig ⁿ   Perry, James A ^g   Poterba, Timothy ^a,c   Seed, Cotton ^a,c   Surakka, Ida L ^k   Esko, Tonu ^l   Ripatti, Samuli ^k   Salomaa, Veikko ^k   Correa, Adolfo ^o   Vasan, Ramachandran S ^d,p,q   Kellis, Manolis ^c,r   Neale, Benjamin M ^a,b,c   Lander, Eric S ^c   Abecasis, Goncalo ^s   Mitchell, Braxton ^g   Rich, Stephen S ^m   Wilson, James G ^o   Cupples, L Adrienne ^d,q   Rotter, Jerome I ^t   Willer, Cristen J ^h   Kathiresan, Sekar ^a,b,c   Abe, Namiko ^u   Albert, Christine ^a   Almasy, Laura ^w,x   Alonso, Alvaro ^y   Ament, Seth ^g   Anderson, Peter ⁿ   Anugu, Pramod ^z   Applebaum Bowden, Deborah ^aa   Arking, Dan ^ab   Arnett, Donna K ^ac   Ashley Koch, Allison ^ad   Aslibekyan, Stella ^ae   Assimes, Tim ^af   Auer, Paul ^ag   Avramopoulos, Dimitrios ^ab   Barnard, John ^ah   Barnes, Kathleen ^ai   Barr, R Graham ^aj   Barron Casella, Emily ^ab   Beaty, Terri ^ab   Becker, Diane ^ab   Becker, Lewis ^ab   Beer, Rebecca ^aa   Begum, Ferdouse ^ab   Beitelshees, Amber ^g   Benjamin, Emelia ^a,ak   Bezerra, Marcos ^al   Bielak, Larry ^s   Bis, Joshua ⁿ   Blackwell, Thomas ^s   Blangero, John ^am   Boerwinkle, Eric ^an   Borecki, Ingrid ⁿ   Bowler, Russell ^ao   Brody, Jennifer ⁿ   Broeckel, Ulrich ^ap   Broome, Jai ⁿ   Bunting, Karen ^u   Burchard, Esteban ^aq   Cardwell, Jonathan ^ai   Carty, Cara ^ar   Casaburi, Richard ^as   Casella, James ^ab   Chang, Christy ^g   Chasman, Daniel ^at   Chavan, Sameer ^ai   Chen, Bo Juen ^u   Chen, Wei Min ^au   Chen, Yii Der Ida ^av   Cho, Michael ^at   Choi, Seung Hoan ^c   Chuang, Lee Ming ^aw   Chung, Mina ^ah   Cornell, Elaine ^ax   Crandall, Carolyn ^as   Crapo, James ^ao   Curran, Joanne ^am   Curtis, Jeffrey ^s   Custer, Brian ^ay   Damcott, Coleen ^g   Darbar, Dawood ^az   Das, Sayantan ^s   David, Sean ^af   Davis, Colleen ⁿ   Daya, Michelle ^ai   de Andrade, Mariza ^ba   DeBaun, Michael ^bb   Deka, Ranjan ^bc   DeMeo, Dawn ^at   Devine, Scott ^g   Do, Ron ^bd   Duan, Qing ^be   Duggirala, Ravi ^am   Durda, Peter ^ax   Dutcher, Susan ^bf   Eaton, Charles ^bg   Ekunwe, Lynette ^z   Ellinor, Patrick ^a   Emery, Leslie ⁿ   Farber, Charles ^au   Farnam, Leanna ^at   Fingerlin, Tasha ^ao   Flickinger, Matthew ^s   Fornage, Myriam ^an   Franceschini, Nora ^be   Fu, Mao ^g   Fullerton, Malia ⁿ   Fulton, Lucinda ^bf   Gabriel, Stacey ^c   Gan, Weiniu ^aa   Gao, Yan ^z   Gass, Margery ^bh   Gelb, Bruce ^bd   Germer, Soren ^u   Gignoux, Chris ^af   Gladwin, Mark ^bi   Glahn, David ^f   Gogarten, Stephanie ⁿ   Gong, Da Wei ^g   Goring, Harald ^am   Gu, C Charles ^bf   Guan, Yue ^g   Guo, Xiuqing ^av   Haessler, Jeff ^ar,bh   Hall, Michael ^z   Harris, Daniel ^g   Hawley, Nicola ^f   He, Jiang ^bj   Heavner, Ben ⁿ   Heckbert, Susan ⁿ   Hernandez, Ryan ^aq   Hersh, Craig ^at   Hidalgo, Bertha ^ae   Hixson, James ^an   Hokanson, John ^ai   Hong, Elliott ^g   Hoth, Karin ^bk   Huston, Haley ^bm   Hwu, Chii Min ^bn   Irvin, Marguerite Ryan ^ae   Jackson, Rebecca ^bo   Jain, Deepti ⁿ   Jaquish, Cashell ^aa   Johnsen, Jill ^n,bm   Johnson, Andrew ^bp   Johnston, Rich ^y   Jones, Kimberly ^ab   Kaplan, Robert ^bq   Kaufman, Laura ^at   Kelly, Shannon ^ay   Kenny, Eimear ^bd   Kessler, Michael ^g   Khan, Alyna ⁿ   Kinney, Greg ^ai   Konkle, Barbara ^bm   Kooperberg, Charles ^bh   Kramer, Holly ^br   Krauter, Stephanie ⁿ   Lange, Christoph ^bs   Lange, Ethan ^ai   Lange, Leslie ^ai   Laurie, Cathy ⁿ   Laurie, Cecelia ⁿ   LeBoff, Meryl ^at   Lee, Wen Jane ^bn   Levine, David ⁿ   Levy, Dan ^bp   Lewis, Joshua ^g   Li, Yun ^be   Lin, Honghuang ^ak   Liu, Simin ^ar,bg   Loos, Ruth ^bd   Lubitz, Steven ^a   Lunetta, Kathryn ^ak   Luo, James ^bp   Mahaney, Michael ^am   Make, Barry ^ab   Manson, JoAnn ^at   Margolin, Lauren ^c   Martin, Lisa ^bt   Mathai, Susan ^ai   Mathias, Rasika ^ab   McArdle, Patrick ^g   McDonald, Merry Lynn ^ae   McFarland, Sean ^bu   McGarvey, Stephen ^bg   Mei, Hao ^z   Meyers, Deborah A ^bv   Mikulla, Julie ^aa   Min, Nancy ^z   Minear, Mollie ^aa   Minster, Ryan L ^bi   Musani, Solomon ^z   Mwasongwe, Stanford ^z   Mychaleckyj, Josyf C ^au   Nadkarni, Girish ^bd   Naik, Rakhi ^ab   Nekhai, Sergei ^bw   Nickerson, Deborah ⁿ   North, Kari ^be   O’Connor, Tim ^g   Ochs Balcom, Heather ^bx   Pankow, James ^by   Papanicolaou, George ^aa   Parker, Margaret ^at   Parsa, Afshin ^g   Penchev, Sara ^ao   Peralta, Juan Manuel ^am   Perez, Marco ^af   Peters, Ulrike ^n,bh   Phillips, Larry ^y   Phillips, Sam ⁿ   Pollin, Toni ^g   Post, Wendy ^ab   Becker, Julia Powers ^ai   Boorgula, Meher Preethi ^ai   Preuss, Michael ^bd   Prokopenko, Dmitry ^bu   Psaty, Bruce ⁿ   Qasba, Pankaj ^aa   Qiao, Dandi ^at   Qin, Zhaohui ^y   Rafaels, Nicholas ^ai   Raffield, Laura ^be   Rao, D C ^bf   Rasmussen Torvik, Laura ^bz   Ratan, Aakrosh ^au   Redline, Susan ^at   Reed, Robert ^g   Regan, Elizabeth ^ao   Reiner, Alex ^n,bh   Rice, Ken ⁿ   Roden, Dan ^bb   Roselli, Carolina ^c   Ruczinski, Ingo ^ab   Russell, Pamela ^ai   Ruuska, Sarah ^bm   Ryan, Kathleen ^g   Sakornsakolpat, Phuwanat ^at   Salimi, Shabnam ^g   Salzberg, Steven ^ab   Sandow, Kevin ^av   Sankaran, Vijay ^bu   Schwander, Karen ^bf   Schwartz, David ^ai   Sciurba, Frank ^bi   Seidman, Christine ^b   Sheehan, Vivien ^ca   Shetty, Amol ^g   Shetty, Aniket ^ai   Sheu, Wayne Hui Heng ^bn   Shoemaker, M Benjamin ^bb   Silver, Brian ^cb   Silverman, Edwin ^at   Smith, Josh ⁿ   Smith, Nicholas ⁿ   Smith, Tanja ^u   Smoller, Sylvia ^bq   Sofer, Tamar ^at   Sotoodehnia, Nona ⁿ   Stilp, Adrienne ⁿ   Streeten, Elizabeth ^g   Sung, Yun Ju ^bf   Sylvia, Jody ^at   Szpiro, Adam ⁿ   Sztalryd, Carole ^g   Tang, Hua ^af   Taub, Margaret ^ab   Taylor, Kent ^av   Taylor, Simeon ^g   Telen, Marilyn ^ad   Thornton, Timothy A ⁿ   Tinker, Lesley ^ar   Tirschwell, David ⁿ   Tiwari, Hemant ^ae   Tracy, Russell ^ax   Tsai, Michael ^by   Vaidya, Dhananjay ^ab   Vrieze, Scott ^by,cc   Walker, Tarik ^ai   Wallace, Robert ^bk   Walts, Avram ^ai   Wan, Emily ^at   Wang, Fei Fei ⁿ   Watson, Karol ^as   Weeks, Daniel E ^bi   Weir, Bruce ⁿ   Weiss, Scott ^at   Weng, Lu Chen ^a   Williams, Kayleen ⁿ   Williams, L Keoki ^cd   Wilson, Carla ^at   Wong, Quenna ⁿ   Xu, Huichun ^g   Yanek, Lisa ^ab   Yang, Ivana ^ai   Yang, Rongze ^g   Zaghloul, Norann ^g   Zhang, Yingze ^bi   Zhao, Snow Xueyan ^ao   Zheng, Xiuwen ⁿ   Zhi, Degui ^an   Zody, Michael ^u   more..

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^e YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f YALE UNIVERSITY   (United States)

^g UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^h UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

ⁱ HARVARD UNIVERSITY   (United States)

^j UNIVERSITY OF CALIFORNIA   (United States)

^k UNIVERSITY OF HELSINKI   (Finland)

^l UNIVERSITY OF TARTU   (Estonia)

^m UNIVERSITY OF VIRGINIA   (United States)

ⁿ UNIVERSITY OF WASHINGTON   (United States)

^o UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^p BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^q FRAMINGHAM HEART STUDY   (United States)

^r MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^s Priscilla)   (United States)

^t HARBOR UCLA MEDICAL CENTER   (United States)

^u NEW YORK GENOME CENTER   (United States)

^v Nichole) Palmer   (United States)

^w CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^x UNIVERSITY OF PENNSYLVANIA   (United States)

^y EMORY UNIVERSITY   (United States)

^z UNIVERSITY OF MISSISSIPPI   (United States)

^aa NATIONAL INSTITUTES OF HEALTH   (United States)

^ab JOHNS HOPKINS UNIVERSITY   (United States)

^ac UNIVERSITY OF KENTUCKY   (United States)

^ad DUKE UNIVERSITY   (United States)

^ae UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^af STANFORD UNIVERSITY   (United States)

^ag UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

^ah LERNER RESEARCH INSTITUTE   (United States)

^ai UNIVERSITY OF COLORADO   (United States)

^aj Och Spine at New York Presbyterian Hospitals   (United States)

^ak BOSTON UNIVERSITY   (United States)

^al Fundacao de Hematologia e Hemoterapia de Pernambuco   (Brazil)

^am University of Texas Rio Grande Valley School of Medicine   (United States)

^an UNIVERSITY OF TEXAS   (United States)

^ao DEPARTMENT OF MEDICINE   (United States)

^ap MEDICAL COLLEGE OF WISCONSIN   (United States)

^aq UNIVERSITY OF CALIFORNIA   (United States)

^ar Women's Health Initiative Clinical Coordinating Center   (United States)

^as UNIVERSITY OF CALIFORNIA   (United States)

^at BRIGHAM AND WOMEN S HOSPITAL   (United States)

^au UNIVERSITY OF VIRGINIA   (United States)

^av LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE   (United States)

^aw NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^ax UNIVERSITY OF VERMONT   (United States)

^ay BLOOD SYSTEMS RESEARCH INSTITUTE   (United States)

^az UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^ba MAYO CLINIC   (United States)

^bb VANDERBILT UNIVERSITY   (United States)

^bc UNIVERSITY OF CINCINNATI   (United States)

^bd MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^be UNIVERSITY OF NORTH CAROLINA   (United States)

^bf WASHINGTON UNIVERSITY   (United States)

^bg BROWN UNIVERSITY   (United States)

^bh Fred Hutchinson Cancer Research Center   (United States)

^bi UNIVERSITY OF PITTSBURGH   (United States)

^bj TULANE UNIVERSITY   (United States)

^bk UNIVERSITY OF IOWA   (United States)

^bl Agnes)   (Taiwan)

^bm BloodWorks Northwest   (United States)

^bn TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^bo THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^bp NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^bq ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^br LOYOLA UNIVERSITY CHICAGO   (United States)

^bs HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^bt GEORGE WASHINGTON UNIVERSITY   (United States)

^bu HARVARD UNIVERSITY   (United States)

^bv UNIVERSITY OF ARIZONA   (United States)

^bw HOWARD UNIVERSITY   (United States)

^bx UNIVERSITY AT BUFFALO   (United States)

^by UNIVERSITY OF MINNESOTA   (United States)

^bz NORTHWESTERN UNIVERSITY   (United States)

^ca BAYLOR COLLEGE OF MEDICINE   (United States)

^cb UMASS MEMORIAL MEDICAL CENTER   (United States)

^cc UNIVERSITY OF COLORADO   (United States)

^cd HENRY FORD HEALTH SYSTEM   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; LIPID;

BLOOD; GENE; GENE EXPRESSION; GENOME; GENOTYPE; LIPID; MUTATION; ORGANIC COMPOUND; PHENOTYPE; PROTEIN;

ADULT; ARTICLE; ATHEROSCLEROSIS; CHOLESTEROL BLOOD LEVEL; EFFECT SIZE; ENHANCER REGION; ETHNICITY; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC CODE; GENETIC VARIABILITY; GENOME ANALYSIS; HAPLOTYPE; HUMAN; HYPERCHOLESTEROLEMIA; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; PROMOTER REGION; QUANTITATIVE TRAIT; TRANSCRIPTION INITIATION SITE; WHOLE GENOME SEQUENCING; BIOLOGICAL MODEL; BLOOD; GENETICS; GENOME-WIDE ASSOCIATION STUDY; HIGH THROUGHPUT SEQUENCING; HUMAN GENOME; MUTATION; NUCLEOTIDE SEQUENCE; PROCEDURES;

BASE SEQUENCE; CHOLESTEROL, LDL; GENE FREQUENCY; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; LIPIDS; MODELS, GENETIC; MUTATION;

EID: 85052245414     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-018-05747-8     Document Type: Article

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