Basic fibroblast growth factor protects against influenza A virus-induced acute lung injury by recruiting neutrophils

Journal of Molecular Cell Biology

Volumn 10, Issue 6, 2018, Pages 573-585

  Wang, Keyu ^a   Lai, Chengcai ^a   Li, Tieling ^b   Wang, Cheng ^b   Wang, Wei ^c   Ni, Bing ^d   Bai, Changqing ^e   Zhang, Shaogeng ^f   Han, Lina ^b   Gu, Hongjing ^a   Zhao, Zhongpeng ^a   Duan, Yueqiang ^a   Yang, Xiaolan ^a   Xing, Li ^a   Zhao, Lingna ^a   Zhou, Shanshan ^a   Xia, Min ^a   Jiang, Chengyu ^c   Wang, Xiliang ^a   Yang, Penghui ^a,f  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

^c INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^d THIRD MILITARY MEDICAL UNIVERSITY   (China)

^e Beijing 307 Hospital   (China)

^f BEIJING 302 HOSPITAL   (China)

Author keywords

FGFR2 PI3K AKT NF B signaling; Influenza H1N1 virus; Neutrophil recruitment; Recombinant FGF2 protein; Therapeutic target

Indexed keywords

CXCL1 CHEMOKINE; EOTAXIN; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 2; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RANTES; STROMAL CELL DERIVED FACTOR 1; RECOMBINANT PROTEIN;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; BRONCHOALVEOLAR LAVAGE FLUID; C57BL 6 MOUSE; CELL ACTIVATION; CELL FUNCTION; CELL PROTECTION; CELL TRANSFER; CHEMOTAXIS; CHEMOTAXIS ASSAY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE EXACERBATION; DISEASE SEVERITY; FEMALE; GENE KNOCKOUT; HOST RESISTANCE; HUMAN; IN VITRO STUDY; INFLUENZA A (H1N1); INFLUENZA A VIRUS; LUNG ALVEOLUS EPITHELIUM CELL; MORTALITY RISK; MOUSE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PI3K/AKT SIGNALING; PRECLINICAL STUDY; PROTEIN BLOOD LEVEL; PROTEIN DEFICIENCY; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RISK REDUCTION; UPREGULATION; WILD TYPE MOUSE; ANIMAL; C57BL MOUSE; COMPLICATION; IMMUNOLOGY; INFLUENZA; INFLUENZA A VIRUS (H1N1); ORTHOMYXOVIRUS INFECTION; VIROLOGY;

ACUTE LUNG INJURY; ANIMALS; FEMALE; FIBROBLAST GROWTH FACTOR 2; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; MICE; MICE, INBRED C57BL; NEUTROPHIL INFILTRATION; ORTHOMYXOVIRIDAE INFECTIONS; RECOMBINANT PROTEINS;

EID: 85051957613     PISSN: 16742788     EISSN: 17594685     Source Type: Journal    
DOI: 10.1093/jmcb/mjx047     Document Type: Article

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