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Volumn 6, Issue 25, 2015, Pages 21468-21478

Nuclear translocation of fibroblast growth factor-2 (FGF2) is regulated by Karyopherin-β2 and Ran GTPase in human glioblastoma cells

Author keywords

Fibroblast growth factor (FGF); Glioblastoma; Nuclear translocation; Phosphatase and tensin homolog (PTEN); Small GTPase

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; KARYOPHERIN BETA; KARYOPHERIN BETA2; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; RAN PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); GUANOSINE 5'-O-(2-THIODIPHOSPHATE); GUANOSINE DIPHOSPHATE; NUCLEOTIDE; RAN PROTEIN, HUMAN; TNPO1 PROTEIN, HUMAN;

EID: 84940773173     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4097     Document Type: Article
Times cited : (17)

References (48)
  • 1
    • 4744372082 scopus 로고    scopus 로고
    • Evolution of the Fgf and Fgfr gene families
    • Itoh N, Ornitz DM. Evolution of the Fgf and Fgfr gene families. Trends in genetics: TIG. 2004; 20:563-569.
    • (2004) Trends in genetics: TIG , vol.20 , pp. 563-569
    • Itoh, N.1    Ornitz, D.M.2
  • 2
    • 0023639110 scopus 로고
    • Synergistic induction of mesoderm by FGF and TGF-beta and the identification of an mRNA coding for FGF in the early Xenopus embryo
    • Kimelman D, Kirschner M. Synergistic induction of mesoderm by FGF and TGF-beta and the identification of an mRNA coding for FGF in the early Xenopus embryo. Cell. 1987; 51:869-877.
    • (1987) Cell , vol.51 , pp. 869-877
    • Kimelman, D.1    Kirschner, M.2
  • 3
    • 0033961133 scopus 로고    scopus 로고
    • An important role for the IIIb isoform of fibroblast growth factor receptor 2 in mesenchymal-epithelial signalling during mouse organogenesis
    • De Moerlooze L, Spencer-Dene B, Revest JM, Hajihosseini M, Rosewell I, Dickson C. An important role for the IIIb isoform of fibroblast growth factor receptor 2 in mesenchymal-epithelial signalling during mouse organogenesis. Development. 2000; 127:483-492.
    • (2000) Development , vol.127 , pp. 483-492
    • De Moerlooze, L.1    Spencer-Dene, B.2    Revest, J.M.3    Hajihosseini, M.4    Rosewell, I.5    Dickson, C.6
  • 4
    • 0038676258 scopus 로고    scopus 로고
    • Regulation of wound healing by growth factors and cytokines
    • Werner S, Grose R. Regulation of wound healing by growth factors and cytokines. Physiological reviews. 2003; 83:835-870.
    • (2003) Physiological reviews , vol.83 , pp. 835-870
    • Werner, S.1    Grose, R.2
  • 5
    • 0030855812 scopus 로고    scopus 로고
    • Antisense targeting of basic fibroblast growth factor and fibroblast growth factor receptor-1 in human melanomas blocks intratumoral angiogenesis and tumor growth
    • Wang Y, Becker D. Antisense targeting of basic fibroblast growth factor and fibroblast growth factor receptor-1 in human melanomas blocks intratumoral angiogenesis and tumor growth. Nature medicine. 1997; 3:887-893.
    • (1997) Nature medicine , vol.3 , pp. 887-893
    • Wang, Y.1    Becker, D.2
  • 6
    • 0033571339 scopus 로고    scopus 로고
    • A high pretreatment serum basic fibroblast growth factor concentration is an independent predictor of poor prognosis in non-Hodgkin's lymphoma
    • Salven P, Teerenhovi L, Joensuu H. A high pretreatment serum basic fibroblast growth factor concentration is an independent predictor of poor prognosis in non-Hodgkin's lymphoma. Blood. 1999; 94:3334-3339.
    • (1999) Blood , vol.94 , pp. 3334-3339
    • Salven, P.1    Teerenhovi, L.2    Joensuu, H.3
  • 9
    • 0026608650 scopus 로고
    • Correlation of basic fibroblast growth factor expression levels with the degree of malignancy and vascularity in human gliomas
    • Takahashi JA, Fukumoto M, Igarashi K, Oda Y, Kikuchi H, Hatanaka M. Correlation of basic fibroblast growth factor expression levels with the degree of malignancy and vascularity in human gliomas. Journal of neurosurgery. 1992; 76:792-798.
    • (1992) Journal of neurosurgery , vol.76 , pp. 792-798
    • Takahashi, J.A.1    Fukumoto, M.2    Igarashi, K.3    Oda, Y.4    Kikuchi, H.5    Hatanaka, M.6
  • 10
    • 0037023780 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 induces translational regulation of Bcl-XL and Bcl-2 via a MEK-dependent pathway: correlation with resistance to etoposide-induced apoptosis
    • Pardo OE, Arcaro A, Salerno G, Raguz S, Downward J, Seckl MJ. Fibroblast growth factor-2 induces translational regulation of Bcl-XL and Bcl-2 via a MEK-dependent pathway: correlation with resistance to etoposide-induced apoptosis. The Journal of biological chemistry. 2002; 277:12040-12046.
    • (2002) The Journal of biological chemistry , vol.277 , pp. 12040-12046
    • Pardo, O.E.1    Arcaro, A.2    Salerno, G.3    Raguz, S.4    Downward, J.5    Seckl, M.J.6
  • 13
    • 0026025825 scopus 로고
    • Alternative initiation of translation determines cytoplasmic or nuclear localization of basic fibroblast growth factor
    • Bugler B, Amalric F, Prats H. Alternative initiation of translation determines cytoplasmic or nuclear localization of basic fibroblast growth factor. Molecular and cellular biology. 1991; 11:573-577.
    • (1991) Molecular and cellular biology , vol.11 , pp. 573-577
    • Bugler, B.1    Amalric, F.2    Prats, H.3
  • 14
    • 0029779287 scopus 로고    scopus 로고
    • Methylation of high molecular weight fibroblast growth factor-2 determines post-translational increases in molecular weight and affects its intracellular distribution
    • Pintucci G, Quarto N, Rifkin DB. Methylation of high molecular weight fibroblast growth factor-2 determines post-translational increases in molecular weight and affects its intracellular distribution. Molecular biology of the cell. 1996; 7:1249-1258.
    • (1996) Molecular biology of the cell , vol.7 , pp. 1249-1258
    • Pintucci, G.1    Quarto, N.2    Rifkin, D.B.3
  • 16
    • 79960912049 scopus 로고    scopus 로고
    • Nuclear import by karyopherin-betas: recognition and inhibition
    • Chook YM, Suel KE. Nuclear import by karyopherin-betas: recognition and inhibition. Biochimica et biophysica acta. 2011; 1813:1593-1606.
    • (2011) Biochimica et biophysica acta , vol.1813 , pp. 1593-1606
    • Chook, Y.M.1    Suel, K.E.2
  • 20
    • 78649650714 scopus 로고    scopus 로고
    • Recognition of nuclear targeting signals by Karyopherin-beta proteins
    • Xu D, Farmer A, Chook YM. Recognition of nuclear targeting signals by Karyopherin-beta proteins. Current opinion in structural biology. 2010; 20:782-790.
    • (2010) Current opinion in structural biology , vol.20 , pp. 782-790
    • Xu, D.1    Farmer, A.2    Chook, Y.M.3
  • 22
    • 0346059590 scopus 로고    scopus 로고
    • Keratinocyte growth factor produced by gastric fibroblasts specifically stimulates proliferation of cancer cells from scirrhous gastric carcinoma
    • Nakazawa K, Yashiro M, Hirakawa K. Keratinocyte growth factor produced by gastric fibroblasts specifically stimulates proliferation of cancer cells from scirrhous gastric carcinoma. Cancer research. 2003; 63:8848-8852.
    • (2003) Cancer research , vol.63 , pp. 8848-8852
    • Nakazawa, K.1    Yashiro, M.2    Hirakawa, K.3
  • 23
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-Kinase AKT pathway in human cancer
    • Vivanco I, Sawyers CL. The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nature reviews Cancer. 2002; 2:489-501.
    • (2002) Nature reviews Cancer , vol.2 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 27
    • 35848929932 scopus 로고    scopus 로고
    • Combination of all-trans retinoic acid and interferon-gamma suppressed PI3K/Akt survival pathway in glioblastoma T98G cells whereas NF-kappaB survival signaling in glioblastoma U87MG cells for induction of apoptosis
    • Zhang R, Banik NL, Ray SK. Combination of all-trans retinoic acid and interferon-gamma suppressed PI3K/Akt survival pathway in glioblastoma T98G cells whereas NF-kappaB survival signaling in glioblastoma U87MG cells for induction of apoptosis. Neurochemical research. 2007; 32:2194-2202.
    • (2007) Neurochemical research , vol.32 , pp. 2194-2202
    • Zhang, R.1    Banik, N.L.2    Ray, S.K.3
  • 28
    • 0021716406 scopus 로고
    • A short amino acid sequence able to specify nuclear location
    • Kalderon D, Roberts BL, Richardson WD, Smith AE. A short amino acid sequence able to specify nuclear location. Cell. 1984; 39:499-509.
    • (1984) Cell , vol.39 , pp. 499-509
    • Kalderon, D.1    Roberts, B.L.2    Richardson, W.D.3    Smith, A.E.4
  • 29
    • 0037018838 scopus 로고    scopus 로고
    • Uncoupling Kapbeta2 substrate dissociation and ran binding
    • Chook YM, Jung A, Rosen MK, Blobel G. Uncoupling Kapbeta2 substrate dissociation and ran binding. Biochemistry. 2002; 41:6955-6966.
    • (2002) Biochemistry , vol.41 , pp. 6955-6966
    • Chook, Y.M.1    Jung, A.2    Rosen, M.K.3    Blobel, G.4
  • 31
    • 0036467506 scopus 로고    scopus 로고
    • Regulation of G(1) cell-cycle progression by oncogenes and tumor suppressor genes
    • Ho A, Dowdy SF. Regulation of G(1) cell-cycle progression by oncogenes and tumor suppressor genes. Current opinion in genetics & development. 2002; 12:47-52.
    • (2002) Current opinion in genetics & development , vol.12 , pp. 47-52
    • Ho, A.1    Dowdy, S.F.2
  • 33
    • 0038782306 scopus 로고    scopus 로고
    • Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth
    • Yu K, Xu J, Liu Z, Sosic D, Shao J, Olson EN, Towler DA, Ornitz DM. Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth. Development. 2003; 130:3063-3074.
    • (2003) Development , vol.130 , pp. 3063-3074
    • Yu, K.1    Xu, J.2    Liu, Z.3    Sosic, D.4    Shao, J.5    Olson, E.N.6    Towler, D.A.7    Ornitz, D.M.8
  • 34
    • 0029928791 scopus 로고    scopus 로고
    • Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3
    • Colvin JS, Bohne BA, Harding GW, McEwen DG, Ornitz DM. Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3. Nature genetics. 1996; 12:390-397.
    • (1996) Nature genetics , vol.12 , pp. 390-397
    • Colvin, J.S.1    Bohne, B.A.2    Harding, G.W.3    McEwen, D.G.4    Ornitz, D.M.5
  • 35
    • 84859629008 scopus 로고    scopus 로고
    • Adult glioblastoma multiforme survival in the temozolomide era: a population-based analysis of Surveillance, Epidemiology, and End Results registries
    • Darefsky AS, King JT Jr, Dubrow R. Adult glioblastoma multiforme survival in the temozolomide era: a population-based analysis of Surveillance, Epidemiology, and End Results registries. Cancer. 2012; 118:2163-2172.
    • (2012) Cancer , vol.118 , pp. 2163-2172
    • Darefsky, A.S.1    King, J.T.2    Dubrow, R.3
  • 36
    • 75149170979 scopus 로고    scopus 로고
    • Fibroblast growth factor signalling: from development to cancer
    • Turner N, Grose R. Fibroblast growth factor signalling: from development to cancer. Nature reviews Cancer. 2010; 10:116-129.
    • (2010) Nature reviews Cancer , vol.10 , pp. 116-129
    • Turner, N.1    Grose, R.2
  • 41
    • 0020188311 scopus 로고
    • A polypeptide domain that specifies migration of nucleoplasmin into the nucleus
    • Dingwall C, Sharnick SV, Laskey RA. A polypeptide domain that specifies migration of nucleoplasmin into the nucleus. Cell. 1982; 30:449-458.
    • (1982) Cell , vol.30 , pp. 449-458
    • Dingwall, C.1    Sharnick, S.V.2    Laskey, R.A.3
  • 42
    • 0034616910 scopus 로고    scopus 로고
    • Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking
    • Bayliss R, Littlewood T, Stewart M. Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking. Cell. 2000; 102:99-108.
    • (2000) Cell , vol.102 , pp. 99-108
    • Bayliss, R.1    Littlewood, T.2    Stewart, M.3
  • 44
    • 84921797642 scopus 로고    scopus 로고
    • Components and regulation of nuclear transport processes
    • Cautain B, Hill R, de Pedro N, Link W. Components and regulation of nuclear transport processes. The FEBS journal. 2015; 282:445-462.
    • (2015) The FEBS journal , vol.282 , pp. 445-462
    • Cautain, B.1    Hill, R.2    de Pedro, N.3    Link, W.4
  • 45
    • 27844445642 scopus 로고    scopus 로고
    • Perturbations of the AKT signaling pathway in human cancer
    • Altomare DA, Testa JR. Perturbations of the AKT signaling pathway in human cancer. Oncogene. 2005; 24:7455-7464.
    • (2005) Oncogene , vol.24 , pp. 7455-7464
    • Altomare, D.A.1    Testa, J.R.2
  • 46
    • 33644513051 scopus 로고    scopus 로고
    • Cooperation between FGF8b overexpression and PTEN deficiency in prostate tumorigenesis
    • Zhong C, Saribekyan G, Liao CP, Cohen MB, Roy-Burman P. Cooperation between FGF8b overexpression and PTEN deficiency in prostate tumorigenesis. Cancer research. 2006; 66:2188-2194.
    • (2006) Cancer research , vol.66 , pp. 2188-2194
    • Zhong, C.1    Saribekyan, G.2    Liao, C.P.3    Cohen, M.B.4    Roy-Burman, P.5
  • 48
    • 0024394549 scopus 로고
    • Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme
    • Andersson S, Davis DL, Dahlback H, Jornvall H, Russell DW. Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme. The Journal of biological chemistry. 1989; 264:8222-8229.
    • (1989) The Journal of biological chemistry , vol.264 , pp. 8222-8229
    • Andersson, S.1    Davis, D.L.2    Dahlback, H.3    Jornvall, H.4    Russell, D.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.