Both IRF3 and especially IRF7 play a key role to orchestrate an effective cerebral inflammatory response in a mouse model of herpes simplex virus encephalitis

Journal of NeuroVirology

Volumn 24, Issue 6, 2018, Pages 761-768

  Canivet, Coraline ^a   Rhéaume, Chantal ^a   Lebel, Manon ^b   Piret, Jocelyne ^a   Gosselin, Jean ^b   Boivin, Guy ^a  

^a LAVAL UNIVERSITY   (Canada)

^b LAVAL UNIVERSITY   (Canada)

Author keywords

Cerebral inflammation; Herpes simplex virus encephalitis; Interferon; Interferon regulatory factors; Mouse

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; GAMMA INTERFERON; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7; INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; TUMOR NECROSIS FACTOR; IRF3 PROTEIN, MOUSE; IRF7 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; HERPES SIMPLEX ENCEPHALITIS; HUMAN ALPHAHERPESVIRUS 1; MALE; MORTALITY RATE; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION LEVEL; VIRUS LOAD; WILD TYPE; ANIMAL; C57BL MOUSE; DISEASE MODEL; IMMUNOLOGY; INFLAMMATION; KNOCKOUT MOUSE; VIROLOGY;

ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; ENCEPHALITIS, HERPES SIMPLEX; INFLAMMATION; INTERFERON REGULATORY FACTOR-3; INTERFERON REGULATORY FACTOR-7; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT;

EID: 85051300834     PISSN: 13550284     EISSN: 15382443     Source Type: Journal    
DOI: 10.1007/s13365-018-0666-9     Document Type: Article

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