Lavatera critica controls systemic insulin resistance by ameliorating adipose tissue inflammation and oxidative stress using bioactive compounds identified by GC–MS

Biomedicine and Pharmacotherapy

Volumn 106, Issue , 2018, Pages 183-191

  Veeramani, Chinnadurai ^a   Alsaif, Mohammed A ^a   Al Numair, Khalid S ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Adipose tissue; HGFD; Inflammation; Insulin resistance; Lavatera critica; Obesity

Indexed keywords

ALPHA TOCOPHEROL; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; BENZENEPROPANOIC ACID; CYTOKINE; GLUCOSE; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; INSULIN; LAVATERA CRITICA LEAF EXTRACT; LEPTIN; LINOLENIC ACID; LIPID HYDROPEROXIDE; MESSENGER RNA; PALMITIC ACID; PHYTOL; PLANT EXTRACT; PROPIONIC ACID DERIVATIVE; STIGMASTEROL; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG; ANTIDIABETIC AGENT; AUTACOID; BIOLOGICAL MARKER;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIABETES MELLITUS; DIET SUPPLEMENTATION; DRUG DETERMINATION; DRUG DOSE INCREASE; DRUG EFFICACY; ERYTHROCYTE; FOOD INTAKE; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HERB; HERBAL MEDICINE; HIGH GRAM FAT DIET; HYPERGLYCEMIA; INFLAMMATION; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; LAVATERA CRITICA; LIPID DIET; MALE; MASS FRAGMENTOGRAPHY; MOUSE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; OXIDATIVE STRESS; PLASMA; PRIORITY JOURNAL; ANIMAL; BLOOD; BODY WEIGHT GAIN; C57BL MOUSE; CHEMISTRY; DRUG EFFECT; EATING; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION REGULATION; GENETICS; GLUCOSE TOLERANCE TEST; ISOLATION AND PURIFICATION; MALVACEAE; MEDICINAL PLANT; METABOLISM; PANNICULITIS; PATHOPHYSIOLOGY; PHYTOTHERAPY; PLANT LEAF; TIME FACTOR;

ADIPOSE TISSUE; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; BIOMARKERS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; EATING; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GENE EXPRESSION REGULATION; GLUCOSE TOLERANCE TEST; HYPOGLYCEMIC AGENTS; INFLAMMATION MEDIATORS; INSULIN; INSULIN RESISTANCE; LEPTIN; MALE; MALVACEAE; MICE, INBRED C57BL; OXIDATIVE STRESS; PANNICULITIS; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; PLANTS, MEDICINAL; TIME FACTORS; WEIGHT GAIN;

EID: 85049049610     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2018.06.121     Document Type: Article

References (50)

1. Martinez, K.E., Tucker, L.A., Bailey, B.W., LeCheminant, J.D., Expanded normal weight obesity and insulin resistance in US adults of the national health and nutrition examination survey. J. Diabetes Res., 2017, 2017, 9502643.
2. Buettner, R., Parhofer, K.G., Woenckhaus, M., Wrede, C.E., Kunz-Schughart, L.A., Schölmerich, J., et al. Defining high-fat-diet rat models: metabolic and molecular effect of different fat types. Mol. Endocrinol. 36 (2006), 485–501.
3. Lee, B.C., Lee, J., Cellular and molecular players in adipose tissue inflammation in the development of obesity-induced insulin resistance. Biochim. Biophys. Acta 1842 (2014), 446–462.
4. Weisberg, S.P., McCann, D., Desai, M., Rosenbaum, M., Leibel, R.L., Ferrante, A.W. Jr, Obesity is associated with macrophage accumulation in adipose tissue. J. Clin. Invest. 112 (2003), 1796–1808.
5. Xu, H., Barnes, G.T., Yang, Q., Tan, G., Yang, D., Chou, C.J., et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J. Clin. Invest. 112 (2003), 1821–1830.
6. Kang, Y.E., Kim, J.M., Joung, K.H., Lee, J.H., You, B.R., Choi, M.J., et al. Roles of adipokines, proinflammatory cytokines, and adipose tissue macrophages in obesity associated insulin resistance in modest obesity and early metabolic dysfunction. PLoS One, 11(4), 2016, 0154003.
7. I, Savini, Catani, M.V., Evangelista, D., Gasperi, V., Avigliano, L., Obesity-associated oxidative stress: strategies finalized to improve redox state. Int. J. Mol. Sci. 14 (2013), 10497–10538.
8. Furukawa, S., Fujita, T., Shimabukuro, M., Iwaki, M., Yamada, Y., Nakajima, Y., et al. Increased oxidative stress in obesity and its impact on metabolic syndrome. J. Clin. Invest. 114 (2004), 1752–1761.
9. Lee, H., Lee, Y.J., Choi, H., Ko, E.H., Kim, J.W., Reactive oxygen species facilitate adipocyte differentiation by accelerating mitotic clonal expansion. J. Biol. Chem. 284 (2009), 10601–10609.
10. Higuchi, M., Dusting, G.J., Peshavariya, H., Jiang, F., Hsiao, S.T., Chan, E.C., Differentiation of human adipose-derived stem cells into fat involves reactive oxygen species and Forkhead box O1 mediated upregulation of antioxidant enzymes. Stem Cells Dev. 22 (2013), 878–888.
11. Horvath, T.L., Andrews, Z.B., Diano, S., Fuel utilization by hypothalamic neurons: roles for ROS. Trends Endocrinol. Metab. 20 (2009), 78–87.
12. Fernandez-Sanchez, A., Madrigal-Santillan, E., Bautista, M., Esquivel-Soto, J., Morales-González, A., Esquivel-Chirino, C., et al. Inflammation, oxidative stress, and obesity. Int. J. Mol. Sci. 12 (2011), 3117–3132.
13. Serra, D., Mera, P., Malandrino, M.I., Mir, J.F., Herrero, L., Mitochondrial fatty acid oxidation in obesity. Antioxid. Redox Signal. 19 (2013), 269–284.
14. Chrysohoou, C., Panagiotakos, D.B., Pitsavos, C., Skoumas, I., Papademetriou, L., Economou, M., The implication of obesity on total antioxidant capacity in apparently healthy men and women: the ATTICA study. Nutr. Metab. Cardiovasc. Dis. 17 (2007), 590–597.
15. Watanabe, Y., Nagai, Y., Honda, H., Okamoto, N., Yamamoto, S., Hamashima, T., et al. Isoliquiritigenin attenuates adipose tissue inflammation in vitro and adipose tissue fibrosis through inhibition of innate immune responses in mice. Sci. Rep., 6, 2016, 23097.
16. Song, H., Zheng, Z., Wu, J., Lai, J., Chu, Q., Zheng, X., White pitaya (hylocereus undatus) juice attenuates insulin resistance and hepatic steatosis in diet-induced obese mice. PLoS One, 11, 2016, 0149670.
17. Banfi, E., Galasso, G., Soldano, A., Notes on systematics and taxonomy for the Italian vascular flora. Atti. Soc. Ital. Sci. Nat. Museo Civ. Stor. Nat. Milano 152 (2011), 85–106.
18. Tardio, J., Pardo-de-Santayna, M., Morales, R., Rivera, D., Obón, C., Botanical review of wild edible plants in Spain. Bot. J. Linn. Soc. 152 (2006), 27–71.
19. Viegi, L., Pieroni, A., Guarrera, P.M., Vangelisti, R., A review of plants used in folk veterinary medicine in Italy as basis for a databank. J. Ethnopharmacol. 89 (2003), 221–244.
20. Ben-Nasr, S., Aazza, S., Mnif, W., Miguel Mda, G., Antioxidant and anti-lipoxygenase activities of extracts from different parts of Lavatera cretica L. grown in Algarve (Portugal). Pharmacogn. Mag. 11 (2015), 48–54.
21. Veeramani, C., Alsaif, M.A., Al-Numair, K.S., Lavatera critica, a green leafy vegetable, controls high fat diet induced hepatic lipid accumulation and oxidative stress through the regulation of lipogenesis and lipolysis genes. Biomed. Pharmacother. 96 (2017), 1349–1357.
22. Trinder, P., Determination of blood glucose using 4-amino phenazone as oxygen acceptor. J. Clin. Pathol., 22, 1969, 246.
23. Bürgi, W., Briner, M., Franken, N., Kessler, A.C., One-step sandwich enzyme immunoassay for insulin using monoclonal antibodies. Clin. Biochem. 21 (1988), 311–314.
24. Matthews, D.R., Hosker, J.P., Rudenski, A.S., Naylor, B.A., Treacher, D.F., Turner, R.C., Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28 (1985), 412–419.
25. -DDCt method. Methods 25 (2001), 402–408.
26. Niehaus, W.G., Samuelson, B., Formation of malondialdehyde from phospholipids arachidonate during microsomal lipid peroxidation. Eur. J. Biochem. 6 (1968), 126–130.
27. Jiang, Z.Y., Hunt, J.V., Wolff, S.P., Ferrous ion oxidation in the presence of xylenol orange for the detection of lipid hydroperoxides in low density lipoprotein. Anal. Biochem. 02 (1992), 384–389.
28. Rotruck, J.T., Pope, A.L., Ganther, H.E., Swanson, A.B., Hafeman, D.G., Hoekstra, W.G., Selenium: biochemical role as a component of glutathione peroxidase. Science 179 (1973), 588–590.
29. Kakkar, P., Das, B., Viswanathan, P.N., A modified spectrophotometric assay of superoxide dismutase. Indian J. Biochem. Biophys. 21 (1984), 130–132.
30. Rahman, I., Kode, A., Biswas, S.K., Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method. Nat. Protoc. 1 (2006), 3159–3165.
31. Ellman, G.L., Tissue sulfhydryl groups. Arch. Biochem. Biophys. 82 (1959), 70–77.
32. Saravanan, S., Pari, L., Role of thymol on hyperglycemia and hyperlipidemia in high fat diet-induced type 2 diabetic C57BL/6J mice. Eur. J. Pharmacol. 761 (2015), 279–287.
33. Musil, F., Blaha, V., Ticha, A., Hyspler, R., Haluzik, M., Lesna, J., Smahelova, A., Sobotka, L., Effects of body weight reduction on plasma leptin and adiponectin/leptin ratio in obese patients with type 1 diabetes mellitus. Physiol. Res. 64 (2015), 221–228.
34. Sari, R., Balci, M.K., Apaydin, C., The relationship between plasma leptin levels and chronic complication in patients with type 2 diabetes mellitus. Metab. Syndr. Relat. Disord. 8 (2010), 499–503.
35. Wang, J., Huang, M., Yang, J., Ma, X., Zheng, S., Deng, S., et al. Anti-diabetic activity of stigmasterol from soybean oil by targeting the GLUT4 glucose transporter. Food Nutr. Res., 61(1), 2017 1364117.
36. Polyzos, S.A., Kountouras, J., Mantzoros, C.S., Polymerou, V., Katsinelos, P., Effects of combined low-dose spironolactone plus vitamin E vs vitamin E monotherapy on insulin resistance, non-invasive indices of steatosis and fibrosis, and adipokine levels in non-alcoholic fatty liver disease: a randomized controlled trial 2017. Diabetes Obes. Metab. 19:12 (2017), 1805–1809.
37. Elmazar, M.M., El-Abhar, H.S., Schaalan, M.F., Farag, N.A., Phytol/Phytanic acid and insulin resistance: potential role of phytanic acid proven by docking simulation and modulation of biochemical alterations. PLoS One, 8(1), 2013, e45638.
38. Gordon, S., Taylor, P.R., Monocyte and macrophage heterogeneity. Nat. Rev. Immunol. 5 (2005), 953–964.
39. Navarro, A., De las Heras, B., Villar, A., Anti-inflammatory and immunomodulating properties of a sterol fraction from Sideritis foetens,. Clem. Biol. Pharm. Bull. 24:5 (2001), 470–473.
40. Al-Asmari, A.K., Khan, A.Q., Al-Asmari, S.A., Al-Rawi, A., Al-Omani, S., Alleviation of 5-fluorouracil-induced intestinal mucositis in rats by vitamin E via targeting oxidative stress and inflammatory markers. J. Complement. Integr. Med. 13:4 (2016), 377–385.
41. Chowdhury, R.R., Ghosh, S.K., Phytol-derived novel isoprenoid immunostimulants. Front. Immunol., 3, 2012, 49.
42. Charradi, K.S., Elkahoui, F.L., Aouani, E., High-fat diet induced an oxidative stress in white adipose tissue and disturbed plasma transition metals in rat: prevention by grape seed and skin extract. J. Physiol. Sci. 63 (2013), 445–455.
43. Keaney, J.F.Jr., Larson, M.G., Vasan, R.S., Wilson, P.W., Lipinska, I., Corey, D., et al. Obesity and systemic oxidative stress clinical correlates of oxidative stress in the Framingham study. Arterioscler. Thromb. Vasc. Biol. 23 (2003), 434–439.
44. Olusi, S., Obesity is an independent risk factor for plasma lipid peroxidation and depletion of erythrocyte cytoprotectic enzymes in humans. Int. J. Obes. Relat. Metab. Disord. 26 (2002), 1159–1164.
45. Bloomer, R.J., Kabir, M.M., Marshall, K.E., Canale, R.E., Farney, T.M., Postprandial oxidative stress in response to dextrose and lipid meals of differing size. Lipids Health Dis. 9 (2010), 79–80.
46. Ruskovska, T., Bernlohr, D.A., Oxidative stress and protein carbonylation in adipose tissue-implications for insulin resistance and diabetes mellitus. J. Proteom. 92 (2013), 323–334.
47. Wang, M., Zhang, X.J., Feng, K., He, C., Li, P., Hu, Y.J., et al. Dietary α-linolenic acid-rich flaxseed oil prevents against alcoholic hepatic steatosis via ameliorating lipid homeostasis at adipose tissue-liver axis in mice. Sci. Rep., 6, 2016, 26826.
48. Zheng, J.S., Li, K., Huang, T., Chen, Y., Xie, H., Xu, D., et al. Genetic risk score of nine type 2 diabetes risk variants that interact with erythrocyte phospholipid alpha-linolenic acid for type 2 diabetes in chinese hans: a case-control study. Nutrients, 9(4), 2017, E376.
49. Bucioli, S.A., de Abreu, L.C., Valenti, V.E., Leone, C., Vannucchi, H., Effects of vitamin E supplementation on renal non-enzymatic antioxidants in young rats submitted to exhaustive exercise stress. BMC Complement. Altern. Med., 11, 2011, 133.
50. la Torre Fabiola, V.D., Ralf, K., Gabriel, B., Victor Ermilo, A.A., Martha, M.G., Mirbella, C.F., et al. Anti-inflammatory and immunomodulatory effects of Critonia aromatisans leaves: downregulation of pro-inflammatory cytokines. J. Ethnopharmacol. 190 (2016), 174–182.