TRIF deficiency protects non-obese diabetic mice from type 1 diabetes by modulating the gut microbiota and dendritic cells

Journal of Autoimmunity

Volumn 93, Issue , 2018, Pages 57-65

  Gülden, Elke ^a   Chao, Chen ^a,b   Tai, Ningwen ^a   Pearson, James A ^a   Peng, Jian ^a   Majewska Szczepanik, Monika ^a,c   Zhou, Zhiguang ^b   Wong, F Susan ^d   Wen, Li ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^d CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; BACTERIAL DNA; CD11B ANTIGEN; CD19 ANTIGEN; CD69 ANTIGEN; GLYCOPROTEIN P 15095; HERMES ANTIGEN; INTERLEUKIN 17; INTERLEUKIN 6; L SELECTIN; RNA 16S; TIR DOMAIN CONTAINING ADAPTER INDUCING INTERFERON BETA; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; MYD88 PROTEIN, MOUSE; MYELOID DIFFERENTIATION FACTOR 88; TICAM-1 PROTEIN, MOUSE; TLR3 PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; DENDRITIC CELL; DIABETOGENESIS; FECES MICROFLORA; FEMALE; FIRMICUTES; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IMMUNOMODULATION; IN VITRO STUDY; INFLAMMATION; INNATE IMMUNITY; INSULIN DEPENDENT DIABETES MELLITUS; INTESTINE FLORA; LYMPHOCYTE PROLIFERATION; MICROBIAL COMMUNITY; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PRIORITY JOURNAL; PROTEOBACTERIA; REGULATORY T LYMPHOCYTE; RIKENELLACEAE; SPECIES COMPOSITION; STRAIN DIFFERENCE; SUTTERELLA; SYMBIOSIS; T LYMPHOCYTE ACTIVATION; TURICIBACTER; WILD TYPE MOUSE; ADOPTIVE TRANSFER; ANIMAL; BACTEROIDETES; BURKHOLDERIALES; CELL PROLIFERATION; DISEASE PREDISPOSITION; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; MICROBIOLOGY; PATHOLOGY; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TRANSPLANTATION;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ADOPTIVE TRANSFER; ANIMALS; BACTEROIDETES; BURKHOLDERIALES; CELL PROLIFERATION; DENDRITIC CELLS; DIABETES MELLITUS, EXPERIMENTAL; DISEASE SUSCEPTIBILITY; FEMALE; FIRMICUTES; GASTROINTESTINAL MICROBIOME; GENE EXPRESSION REGULATION; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED NOD; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TOLL-LIKE RECEPTOR 3; TOLL-LIKE RECEPTOR 4;

EID: 85049021279     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2018.06.003     Document Type: Article

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