Cell-specific prediction and application of drug-induced gene expression profiles

Pacific Symposium on Biocomputing

Volumn 0, Issue 212669, 2018, Pages 32-43

  Hodos, Rachel ^a,b,c   Zhang, Ping ^d   Lee, Hao Chih ^a,b   Duan, Qiaonan ^a,e,f   Wang, Zichen ^a,e,f   Clark, Neil R ^a,e,f   Ma’ayan, Avi ^a,e,f   Wang, Fei ^d,g   Kidd, Brian ^a,b,h   Hu, Jianying ^d   Sontag, David ⁱ   Dudley, Joel ^a,b,h  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b ISMMS ^*  (United States)

^c NEW YORK UNIVERSITY   (United States)

^d IBM T J WATSON RESEARCH CENTER   (United States)

^e Department of Genetics and Genomic Sciences   (United States)

^f BD2K LINCS Data Coordination and Integration Center   (United States)

^g WEILL CORNELL MEDICAL COLLEGE   (United States)

^h ISMMS   (United States)

ⁱ Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

Chemogenomics; Drug discovery; Drug repurposing; Gene expression; Tensor completion

Indexed keywords

CYTOLOGY; DRUG PRODUCTS; FORECASTING; OUTSOURCING; TENSORS;

CHEMOGENOMICS; DIFFERENTIALLY EXPRESSED GENE; DRUG DISCOVERY; GENE EXPRESSION PROFILES; GENE EXPRESSION PROFILING; REPURPOSING; TENSOR COMPLETION; THREE DIMENSIONAL ARRAYS;

GENE EXPRESSION;

TRANSCRIPTOME;

ALGORITHM; BIOLOGY; CELLS; DRUG DATABASE; DRUG DEVELOPMENT; DRUG EFFECT; DRUG REPOSITIONING; EVALUATION STUDY; GENE EXPRESSION PROFILING; GENETIC DATABASE; HUMAN; METABOLISM; PROCEDURES; STATISTICS AND NUMERICAL DATA; VALIDATION STUDY;

ALGORITHMS; CELLS; COMPUTATIONAL BIOLOGY; DATABASES, GENETIC; DATABASES, PHARMACEUTICAL; DRUG DISCOVERY; DRUG REPOSITIONING; GENE EXPRESSION PROFILING; HUMANS; TRANSCRIPTOME;

EID: 85048488961     PISSN: 23356928     EISSN: 23356936     Source Type: Journal    
DOI: 10.1142/9789813235533_0004     Document Type: Conference Paper

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