Saracatinib inhibits middle east respiratory syndrome-coronavirus replication in vitro

Viruses

Volumn 10, Issue 6, 2018, Pages

  Shin, Jin Soo ^a,b   Jung, Eunhye ^a   Kim, Meehyein ^a,c   Baric, Ralph S ^d   Go, Yun Young ^a,c  

^a Korea Research Institute of Chemical Technology   (South Korea)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^c University of Science and Technology (UST)   (South Korea)

^d University of North Carolina at Chapel Hill   (United States)

Author keywords

Gemcitabine; MERS CoV; Middle East Respiratory Syndrome; Saracatinib; Src family kinase inhibitor

Indexed keywords

GEMCITABINE; PROTEIN TYROSINE KINASE; SARACATINIB; 1,3 BENZODIOXOLE DERIVATIVE; ANTIVIRUS AGENT; DEOXYCYTIDINE; ENZYME INHIBITOR; QUINAZOLINE DERIVATIVE;

ANTIVIRAL ACTIVITY; ARTICLE; CC50; CORONAVIRINAE; CYTOTOXICITY; EC50; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VITRO STUDY; LIFE CYCLE; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; MUTATION; PLAQUE ASSAY; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY TRACT DISEASE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; RNAI THERAPEUTICS; VIRAL PLAQUE ASSAY; VIRUS INFECTION; VIRUS REPLICATION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CELL LINE; CROSS INFECTION; DNA REPLICATION; DRUG DEVELOPMENT; DRUG EFFECT; MOLECULAR LIBRARY;

ANTIVIRAL AGENTS; BENZODIOXOLES; CELL LINE; CROSS INFECTION; DEOXYCYTIDINE; DNA REPLICATION; DRUG DISCOVERY; ENZYME INHIBITORS; HUMANS; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; QUINAZOLINES; SMALL MOLECULE LIBRARIES; SRC-FAMILY KINASES; VIRUS REPLICATION;

EID: 85047872591     PISSN: None     EISSN: 19994915     Source Type: Journal    
DOI: 10.3390/v10060283     Document Type: Article

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