A mechanistic analysis of nitric oxide-induced cellular toxicity

Nitric Oxide - Biology and Chemistry

Volumn 1, Issue 2, 1997, Pages 130-144

  Burney, Samar ^a   Tamir, Snait ^a   Gal, Aaron ^a   Tannenbaum, Steven R ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NITRIC OXIDE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE; CELL DAMAGE; CELL DEATH; CHO CELL; CONTROLLED STUDY; CYTOTOXICITY; DNA STRAND BREAKAGE; DNA SYNTHESIS INHIBITION; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL; MEMBRANE DAMAGE; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0031406827     PISSN: 10898603     EISSN: None     Source Type: Journal    
DOI: 10.1006/niox.1996.0114     Document Type: Article

References (48)

1. Hibbs J. B, Taintor R. R., Vavrin Z., Rachlin E. M. Nitric oxide: A cytotoxic activated macrophage effector molecule. Biochem. Biophys. Res. Commun. 157:1988;87-94.
2. Bonfoco E., Krainc D., Ankarcron M., Nicotera P. L., Lipton S. A. Apoptosis and necrosis: Two distinct events induced, respectively, by mild and intense insults withND. Proc. Natl. Acad. Sci. USA. 92:1995;7162-7166.
3. Tamir S., Burney S., Tannenbaum S. R. DNA damage by nitric oxide. Chem. Res. Toxicol. 9:1996;821-827.
4. Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB J. 6:1992;3051-3064.
5. deRojas-Walker T., Tamir S., Ji H., Wishnok J. S., Tannenbaum S. R. Nitric oxide induces oxidative damage in addition to deamination in macrophage DNA. Chem. Res. Toxicol. 8:1995;473-477.
6. Tamir S., deRojas-Walker T., Wishnok J. S., Tannenbaum S. R. DNA damage and genotoxicity by nitric oxide. Methods in Enzymology: Nitric Oxide. 1996;Academic Press, New York. p. 230-243.
7. Beckman J. S. Oxidative damage and tyrosine nitration by peroxynitrite. Chem. Res. Toxicol. 9:1996;836-844.
8. Tamir S., Lewis R. S., deRojas-Walker, Deen W. M., Wishnok J. S., Tannenbaum S. R. The influence of delivery rate on the chemistry and biological effects of nitric oxide. Chem. Res. Toxicol. 6:1993;895-899.
9. 15. Anal. Biochem. 126:1982;131-138.
10. Furth E. E., Thilly W. G., Penman B. W., Liber H. L., Rand W. M. Quantitative assay for mutation in diploid human lymphoblasts using microtiter plates. Anal. Biochem. 110:1981;1-8.
11. Darzynkiewicz Z., Traganos F., Staiano-Coico L., Kapuscinski J., Melamed M. R. Interactions of rhodamine 123 with living cells studied by flow cytometry. Cancer Res. 42:1982;799-806.
12. Lepoivre M., Flaman J-M., Bobe P., Lemaire G., Henry Y. Quenching of the tyrosyl free radical of ribonucleotide reductase by nitric oxide. J. Biol. Chem. 269:1994;21891-21897.
13. Nicoletti I., Migliorati G., Pagliacci M. C., Grignani F., Riccardi C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods. 139:1991;271-279.
14. Nguyen T., Brunson D., Crespi C. L., Penman B. W., Wishnok J. S., Tannenbaum S. R. DNA damage and mutation in human cells exposed to nitric oxidein vitro. Proc. Natl. Acad. Sci. USA. 89:1992;3030-3034.
15. 22. J. Neuropathol. Exp. Neurol. 55:1996;36-43.
16. Albina J. E., Cui S., Mateo R. B., Reichner J. S. Nitric oxide-mediated apoptosis in murine peritoneal macrophages. J. Immunol. 150:1993;5080-5085.
17. Fehsel K., Kroncke K-D., Meyer K. L., Huber H., Wahn V., Kolb-Bachofen V. Nitric oxide induces apoptosis in mouse thymocytes. J. Immunol. 155:1995;2858-2865.
18. Singer I. I., Kawka D. W., Scott S., Weidner J. R., Mumford R. A., Riehl T. E., Stenson W. F. Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease. Gastroenterology. 111:1996;871-885.
19. Lipton S. A., Choi Y-B., Pan Z-H., Lei S. Z., Vincent Chen H-S., Sucher N. J., Loscalzo J., Singel D. J., Stamler J. S. A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature. 364:1993;626-632.
20. Ionnidis I., Groot H. Cytotoxicity of nitric oxide in Fu5 rat hepatoma cells: Evidence for co-operative action with hydrogen peroxide. Biochem. J. 296:1993;341-345.
21. Cui S., Reichner J. S., Mateo R. B., Albina J. E. Activated murine macrophages induce apoptosis in tumor cells through nitric oxide-dependent or -independent mechanisms. Cancer Res. 54:1994;2462-2467.
22. Kroncke K-D., Brenner H-H., Rodriguez M-L., Etzkorn K., Noack E. A., Kolb H., Kolb-Bachofen V. Pancreatic islet cells are highly susceptible towards the cytotoxic effects of chemically generated nitric oxide. Biochim. Biophys. Acta. 1182:1993;221-229.
23. Messner U. K., Brune B. Nitric oxide (NO) in apoptotic versus necrotic RAW 264.7 macrophage cell death: The role of NO-donor exposure, NAD+ content, and p53 accumulation. Arch. Biochem. Biophys. 327:1996;1-10.
24. Messner U. K., Brune B. Modification of macrophage glyceraldehyde-3-phosphate dehydrogenase in response to nitric oxide. Eur. J. Pharmacol. 302:1996;171-182.
25. Rubbo H., Darley-Usmar V., Freeman B. A. Nitric oxide regulation of tissue free radical injury. Chem. Res. Toxicol. 9:1996;809-820.
26. Radi R. Reactions of nitric oxide with metalloproteins. Chem. Res. Toxicol. 9:1996;828-835.
27. Richter C., Schweizer M., Cossarizza A., Franceschi C. Control of apoptosis by the cellular ATP level. FEBS Lett. 378:1996;107-110.
28. 2+. FEBS Lett. 325:1993;104-107.
29. Gross S. S., Wolin M. S. Nitric oxide: Pathophysiological mechanisms. Annu. Rev. Physiol. 57:1995;737-769.
30. Roy B., Lepoivre M., Henry Y., Fontecave M. Inhibition of ribonucleotide reductase by nitric oxide derived from thionitrites: Reversible modifications of both subunits. Biochemistry. 34:1995;5411-5418.
31. Kwon N., Stuehr D. J., Nathan C. F. Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide. J. Exp. Med. 174:1991;761-767.
32. Elledge S. J., Davis R. W. DNA damage induction of ribonucleotide reductase. Mol. Cell. Biol. 9:1989;4932-4940.
33. Kaufmann W. K., Paules R. S. DNA damage and cell cycle checkpoints. FASEB J. 10:1996;238-247.
34. Takagi K., Isobe Y., Yasukawa K., Okouchi E., Suketa Y. Nitric oxide blocks the cell cycle of mouse macrophage-like cells in the early G2+M phase. FEBS Lett. 340:1994;159-162.
35. WAF1. Oncogene. 12:1996;1077-1082.
36. Lane D. P. p53, guardian of the genome. Nature. 358:1992;15-16.
37. Moro F., Ottaggio L., Bonatti S., Simili M., Miele M., Bozzo S., Abbondandolo. p53 expression in normal vs transformed mammalian cells. Carcinogenesis. 16:1995;2435-2440.
38. Little J. B., Nagasawa P. C., Keng P. C., Yu Y., Li C. Y. Absence of radiation-induced G1 arrest in two closely related human lymphoblast cell lines that differ in p53 status. J. Biol. Chem. 270:1995;11033-11036.
39. Forrester K., Ambs S., Lupold S. E., Kapust R. B., Spillare E. A., Weinberg W. C., Felly-Bosco E., Wang X. W., Geller D. A., Tzeng E., Billiar T. R., Harris C. C. Nitric oxide-induced p53 accumulation and regulation of inducible nitric oxide synthase expression by wild-type p53. Proc. Natl. Acad. Sci. USA. 93:1996;2442-2447.
40. Messner U. K., Ankarcrona M., Nicotera P., Brune B. p53 expression in nitric oxide-induced apoptosis. FEBS Lett. 355:1994;23-26.
41. Ho Y. S., Wang Y. J., Lin J. K. Induction of p53 and p21/WAF1/CIP1 expression by nitric oxide and their association with apoptosis in human cancer cells. Mol. Carcinog. 16:1996;21-31.
42. Messner U. K., Reed J. C., Brunes B. BCl-2 protects macrophages from nitric oxide-induced apoptosis. J. Biol. Chem. 271:1996;20192-20197.
43. Strasser A., Harris A. W., Jacks T., Cory S. DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by BCl-2. Cell. 79:1994;329-339.
44. Albina J. E., Martin B-A., Henry W. L., Louis C. A., Reichner J. S. B cell lymphoma-2 transfected P815 cells resist reactive nitrogen intermediate-mediated macrophage-dependent cytotoxicity. J. Immunol. 157:1996;279-283.
45. Zhang J., Dawson V. L., Dawson T. M., Snyder S. H. Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity. Science. 263:1994;687-689.
46. Heller B., Wang Z-Q., Wagner E. F., Radons J., Burkles A., Fehsel K., Burkart V., Kolb H. Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells. J. Biol. Chem. 270:1995;11176-11180.
47. Szabo C., Zingarelli B., O'Connor M., Salzman A. L. DNA strand breakage, activation of poly(ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity in macrophages and smooth muscle cells exposed to peroxynitrite. Proc. Natl. Acad. Sci. USA. 93:1996;1753-1758.
48. Luperchio S., Tamir S., Tannenbaum S. R. NO-induced oxidative stress and glutathione metabolism in rodent and human cells. Free Radical Biol. Med. 21:1996;513-519.