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Volumn 22, Issue 2, 2010, Pages 155-165

APOE ε4 and cognitive dysfunction in multiple sclerosis: A review

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E4; CHOLINE; CREATINE; CREATININE; INTERFERON BETA SERINE; N ACETYLASPARTIC ACID;

EID: 85047684775     PISSN: 08950172     EISSN: None     Source Type: Journal    
DOI: 10.1176/jnp.2010.22.2.155     Document Type: Review
Times cited : (20)

References (102)
  • 1
    • 0025731153 scopus 로고
    • Cognitive dysfunction in multiple sclerosis, I: Frequency, patterns, and prediction
    • Rao SM, Leo GJ, Bernardin L, et al: Cognitive dysfunction in multiple sclerosis, I: frequency, patterns, and prediction. Neurology 1991; 41:685-691
    • (1991) Neurology , vol.41 , pp. 685-691
    • Rao, S.M.1    Leo, G.J.2    Bernardin, L.3
  • 2
    • 0025777432 scopus 로고
    • Cognitive dysfunction in multiple sclerosis, II: Impact on employment and social functioning
    • Rao SM, Leo GJ, Ellington L, et al: Cognitive dysfunction in multiple sclerosis, II: impact on employment and social functioning. Neurology 1991; 41:692-696
    • (1991) Neurology , vol.41 , pp. 692-696
    • Rao, S.M.1    Leo, G.J.2    Ellington, L.3
  • 3
    • 0026015396 scopus 로고
    • The prevalence of cognitive impairment in a community survey of multiple sclerosis
    • McIntosh-Michaelis SA, Roberts MH, Wilkinson SM, et al: The prevalence of cognitive impairment in a community survey of multiple sclerosis. Br J Clin Psychol 1991; 30(part 4):333-348
    • (1991) Br J Clin Psychol , vol.30 , Issue.PART 4 , pp. 333-348
    • McIntosh-Michaelis, S.A.1    Roberts, M.H.2    Wilkinson, S.M.3
  • 4
    • 55549127927 scopus 로고    scopus 로고
    • Cognitive impairment in multiple sclerosis
    • Chiaravalloti ND, DeLuca J: Cognitive impairment in multiple sclerosis. Lancet Neurol 2008; 7:1139-1151
    • (2008) Lancet Neurol , vol.7 , pp. 1139-1151
    • Chiaravalloti, N.D.1    Deluca, J.2
  • 5
    • 58149090341 scopus 로고    scopus 로고
    • Cognitive impairment in multiple sclerosis
    • Patti F: Cognitive impairment in multiple sclerosis. Mult Scler 2009; 15:2-8
    • (2009) Mult Scler , vol.15 , pp. 2-8
    • Patti, F.1
  • 6
    • 33646844323 scopus 로고    scopus 로고
    • Multiple sclerosis-related cognitive changes: A review of cross-sectional and longitudinal studies
    • DOI 10.1016/j.jns.2005.08.019, PII S0022510X06000979
    • Amato MP, Zipoli V, Portaccio E: Multiple sclerosis-related cognitive changes: a review of cross-sectional and longitudinal studies. J Neurol Sci 2006; 245:41-46 (Pubitemid 43775956)
    • (2006) Journal of the Neurological Sciences , vol.245 , Issue.1-2 , pp. 41-46
    • Amato, M.P.1    Zipoli, V.2    Portaccio, E.3
  • 9
    • 0019209359 scopus 로고
    • Disability and intellectual function in multiple sclerosis patients
    • DOI 10.1097/00005053-198012000-00009
    • Marsh GG: Disability and intellectual function in multiple sclerosis patients. J Nerv Ment Dis 1980; 168:758-762 (Pubitemid 11209780)
    • (1980) Journal of Nervous and Mental Disease , vol.168 , Issue.12 , pp. 758-762
    • Marsh, G.G.1
  • 10
    • 0021803965 scopus 로고
    • Chronic progressive multiple sclerosis. Relationship between cerebral ventricular size and neuropsychological impairment
    • Rao SM, Glatt S, Hammeke TA, et al: Chronic progressive multiple sclerosis relationship between cerebral ventricular size and neuropsychological impairment. Arch Neurol 1985; 42:678-682 (Pubitemid 15062824)
    • (1985) Archives of Neurology , vol.42 , Issue.7 , pp. 678-682
    • Rao, S.M.1    Glatt, S.2    Hammeke, T.A.3
  • 11
    • 1842790394 scopus 로고    scopus 로고
    • The neuropsychology of multiple sclerosis: Contributions of neuroimaging research
    • Wishart HA, Flashman L, Saykin AJ: The neuropsychology of multiple sclerosis: contributions of neuroimaging research. Curr Psychiatry Rep 2001; 3:373-378
    • (2001) Curr Psychiatry Rep , vol.3 , pp. 373-378
    • Wishart, H.A.1    Flashman, L.2    Saykin, A.J.3
  • 12
    • 33644842181 scopus 로고    scopus 로고
    • The role of MRS and fMRI in multiple sclerosis
    • Tartaglia MC, Arnold DL: The role of MRS and fMRI in multiple sclerosis. Adv Neurol 2006; 98:185-202
    • (2006) Adv Neurol , vol.98 , pp. 185-202
    • Tartaglia, M.C.1    Arnold, D.L.2
  • 13
    • 33646836430 scopus 로고    scopus 로고
    • MRI markers of destructive pathology in multiple sclerosis-related cognitive dysfunction
    • DOI 10.1016/j.jns.2005.07.014, PII S0022510X06001122
    • Rovaris M, Comi G, Filippi M: MRI markers of destructive pathology in multiple sclerosis-related cognitive dysfunction. J Neurol Sci 2006; 245:111-116 (Pubitemid 43775933)
    • (2006) Journal of the Neurological Sciences , vol.245 , Issue.1-2 , pp. 111-116
    • Rovaris, M.1    Comi, G.2    Filippi, M.3
  • 14
    • 33747123049 scopus 로고    scopus 로고
    • Brain reorganization during attention and memory tasks in multiple sclerosis: Insights from functional MRI studies
    • DOI 10.1016/j.jns.2005.08.024, PII S0022510X06001092
    • Mainero C, Pantano P, Caramia F, et al: Brain reorganization during attention and memory tasks in multiple sclerosis: insights from functional MRI studies. J Neurol Sci 2006; 245:93-98 (Pubitemid 44218704)
    • (2006) Journal of the Neurological Sciences , vol.245 , Issue.1-2 , pp. 93-98
    • Mainero, C.1    Pantano, P.2    Caramia, F.3    Pozzilli, C.4
  • 15
    • 58849132291 scopus 로고    scopus 로고
    • Disconnection as a mechanism for cognitive dysfunction in multiple sclerosis
    • Dineen RA, Vilisaar J, Hlinka J, et al: Disconnection as a mechanism for cognitive dysfunction in multiple sclerosis. Brain 2009; 132:239-249
    • (2009) Brain , vol.132 , pp. 239-249
    • Dineen, R.A.1    Vilisaar, J.2    Hlinka, J.3
  • 16
    • 55149114182 scopus 로고    scopus 로고
    • Structural connectivity influences brain activation during PVSAT in multiple sclerosis
    • Bonzano L, Pardini M, Mancardi GL, et al: Structural connectivity influences brain activation during PVSAT in multiple sclerosis. Neuroimage 2009; 44:9-15
    • (2009) Neuroimage , vol.44 , pp. 9-15
    • Bonzano, L.1    Pardini, M.2    Mancardi, G.L.3
  • 17
    • 51649084084 scopus 로고    scopus 로고
    • A magnetic resonance imaging voxel-based morphometry study of regional gray matter atrophy in patients with benign multiple sclerosis
    • Mesaros S, Rovaris M, Pagani E, et al: A magnetic resonance imaging voxel-based morphometry study of regional gray matter atrophy in patients with benign multiple sclerosis. Arch Neurol 2008; 65:1223-1230
    • (2008) Arch Neurol , vol.65 , pp. 1223-1230
    • Mesaros, S.1    Rovaris, M.2    Pagani, E.3
  • 19
    • 44149103646 scopus 로고    scopus 로고
    • Diffusion weighted callosal integrity reflects interhemispheric communication efficiency in multiple sclerosis
    • Warlop NP, Achten E, Debruyne J, Vingerhoets G: Diffusion weighted callosal integrity reflects interhemispheric communication efficiency in multiple sclerosis. Neuropsychologia 2008; 46:2258-2264
    • (2008) Neuropsychologia , vol.46 , pp. 2258-2264
    • Warlop, N.P.1    Achten, E.2    Debruyne, J.3    Vingerhoets, G.4
  • 20
    • 34548713551 scopus 로고    scopus 로고
    • Thalamic atrophy and cognition in multiple sclerosis
    • Houtchens MK, Benedict RH, Killiany R, et al: Thalamic atrophy and cognition in multiple sclerosis. Neurology 2007; 69:1213-1223
    • (2007) Neurology , vol.69 , pp. 1213-1223
    • Houtchens, M.K.1    Benedict, R.H.2    Killiany, R.3
  • 23
    • 0034575124 scopus 로고    scopus 로고
    • Apolipoprotein E: Far more than a lipid transport protein
    • Mahley RW, Rall SC Jr: Apolipoprotein E: far more than a lipid transport protein. Annu Rev Genomics Hum Genet 2000; 1:507-537
    • (2000) Annu Rev Genomics Hum Genet , vol.1 , pp. 507-537
    • Mahley, R.W.1    Rall Jr., S.C.2
  • 24
    • 65249158083 scopus 로고    scopus 로고
    • Understanding the association of apolipoprotein E4 with Alzheimer's disease: Clues from its structure
    • Zhong N, Weisgraber KH: Understanding the association of apolipoprotein E4 with Alzheimer's disease: clues from its structure. J Biol Chem 2009; 284:6027-6031
    • (2009) J Biol Chem , vol.284 , pp. 6027-6031
    • Zhong, N.1    Weisgraber, K.H.2
  • 25
    • 0027194791 scopus 로고
    • Gene dose of apolipoprotein e type 4 allele and the risk of Alzheimer's disease in late onset families
    • Corder EH, Saunders AM, Strittmatter WJ, et al: Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 1993; 261:921-923
    • (1993) Science , vol.261 , pp. 921-923
    • Corder, E.H.1    Saunders, A.M.2    Strittmatter, W.J.3
  • 26
    • 0029844205 scopus 로고    scopus 로고
    • Human apolipoprotein E: The Alzheimer's disease connection
    • Weisgraber KH, Mahley RW: Human apolipoprotein E: the Alzheimer's disease connection. FASEB J 1996; 10:1485-1494 (Pubitemid 26384445)
    • (1996) FASEB Journal , vol.10 , Issue.13 , pp. 1485-1494
    • Weisgraber, K.H.1    Mahley, R.W.2
  • 27
    • 0036592518 scopus 로고    scopus 로고
    • Non-familial Alzheimer's disease is mainly due to genetic factors
    • Ashford JW, Mortimer JA: Non-familial Alzheimer's disease is mainly due to genetic factors. J Alzheimers Dis 2002; 4:169-177 (Pubitemid 35006049)
    • (2002) Journal of Alzheimer's Disease , vol.4 , Issue.3 , pp. 169-177
    • Ashford, J.W.1    Mortimer, J.A.2
  • 28
    • 2542502430 scopus 로고    scopus 로고
    • ApoE genotype accounts for the vast majority of AD risk and AD pathology
    • DOI 10.1016/j.neurobiolaging.2003.12.023, PII S0197458004001009
    • Raber J, Huang Y, Ashford JW: APOE genotype accounts for the vast majority of AD risk and AD pathology. Neurobiol Aging 2004; 25:641-650 (Pubitemid 38686487)
    • (2004) Neurobiology of Aging , vol.25 , Issue.5 , pp. 641-650
    • Raber, J.1    Huang, Y.2    Ashford, J.W.3
  • 30
    • 57749171545 scopus 로고    scopus 로고
    • Anatomically-distinct genetic associations of APOE epsilon4 allele load with regional cortical atrophy in Alzheimer's disease
    • Filippini N, Rao A, Wetten S, et al: Anatomically-distinct genetic associations of APOE epsilon4 allele load with regional cortical atrophy in Alzheimer's disease. Neuroimage 2009; 44:724-728
    • (2009) Neuroimage , vol.44 , pp. 724-728
    • Filippini, N.1    Rao, A.2    Wetten, S.3
  • 31
    • 0031911493 scopus 로고    scopus 로고
    • Apolipoprotein e genotype influences cognitive phenotype' in patients with Alzheimer's disease but not in healthy control subjects
    • Smith GE, Bohac DL, Waring SC, et al: Apolipoprotein E genotype influences cognitive phenotype in patients with Alzheimer's disease but not in healthy control subjects. Neurology 1998; 50:355-362 (Pubitemid 28119770)
    • (1998) Neurology , vol.50 , Issue.2 , pp. 355-362
    • Smith, G.E.1    Bohac, D.L.2    Waring, S.C.3    Kokmen, E.4    Tangalos, E.G.5    Ivnik, R.J.6    Petersen, R.C.7
  • 33
    • 10044243556 scopus 로고    scopus 로고
    • Apolipoprotein e and cognitive performance: A meta-analysis
    • Small BJ, Rosnick CB, Fratiglioni L, et al: Apolipoprotein E and cognitive performance: a meta-analysis. Psychol Aging 2004; 19:592-600
    • (2004) Psychol Aging , vol.19 , pp. 592-600
    • Small, B.J.1    Rosnick, C.B.2    Fratiglioni, L.3
  • 34
    • 0034606329 scopus 로고    scopus 로고
    • Memory performance and the apolipoprotein e polymorphism in a community sample of middle-aged adults
    • Flory JD, Manuck SB, Ferrell RE, et al: Memory performance and the apolipoprotein E polymorphism in a community sample of middle-aged adults. Am J Med Genet 2000; 96:707-711
    • (2000) Am J Med Genet , vol.96 , pp. 707-711
    • Flory, J.D.1    Manuck, S.B.2    Ferrell, R.E.3
  • 35
    • 29844448115 scopus 로고    scopus 로고
    • Apolipoprotein e genotype and age-related myelin breakdown in healthy individuals: Implications for cognitive decline and dementia
    • DOI 10.1001/archpsyc.63.1.63
    • Bartzokis G, Lu PH, Geschwind DH, et al: Apolipoprotein E genotype and age-related myelin breakdown in healthy individuals: implications for cognitive decline and dementia. Arch Gen Psychiatry 2006; 63:63-72 (Pubitemid 43037470)
    • (2006) Archives of General Psychiatry , vol.63 , Issue.1 , pp. 63-72
    • Bartzokis, G.1    Lu, P.H.2    Geschwind, D.H.3    Edwards, N.4    Mintz, J.5    Cummings, J.L.6
  • 38
    • 44649190480 scopus 로고    scopus 로고
    • Reduced cortical thickness in hippocampal subregions among cognitively normal apolipoprotein e e4 carriers
    • Burggren AC, Zeineh MM, Ekstrom AD, et al: Reduced cortical thickness in hippocampal subregions among cognitively normal apolipoprotein E e4 carriers. Neuroimage 2008; 41:1177-1183
    • (2008) Neuroimage , vol.41 , pp. 1177-1183
    • Burggren, A.C.1    Zeineh, M.M.2    Ekstrom, A.D.3
  • 40
    • 33646891712 scopus 로고    scopus 로고
    • Apolipoprotein e variants and cognition in healthy individuals: A critical opinion
    • DOI 10.1016/j.brainresrev.2005.10.006, PII S0165017305001542
    • Savitz J, Solms M, Ramesar R: Apolipoprotein E variants and cognition in healthy individuals: a critical opinion. Brain Res Rev 2006; 51:125-135 (Pubitemid 43782534)
    • (2006) Brain Research Reviews , vol.51 , Issue.1 , pp. 125-135
    • Savitz, J.1    Solms, M.2    Ramesar, R.3
  • 42
    • 38049115446 scopus 로고    scopus 로고
    • Apolipoprotein e represents a potent gene-based therapeutic target for the treatment of sporadic Alzheimer's disease
    • Poirier J: Apolipoprotein E represents a potent gene-based therapeutic target for the treatment of sporadic Alzheimer's disease. Alzheimers Dement 2008; 4:S91-97
    • (2008) Alzheimers Dement , vol.4
    • Poirier, J.1
  • 43
    • 62849084822 scopus 로고    scopus 로고
    • COG1410, a novel apolipoprotein-E mimetic, improves functional and morphological recovery in a rat model of focal brain ischemia
    • Tukhovskaya EA, Yukin AY, Khokhlova ON, et al: COG1410, a novel apolipoprotein-E mimetic, improves functional and morphological recovery in a rat model of focal brain ischemia. J Neurosci Res 2009; 87:677-682
    • (2009) J Neurosci Res , vol.87 , pp. 677-682
    • Tukhovskaya, E.A.1    Yukin, A.Y.2    Khokhlova, O.N.3
  • 45
    • 36249026518 scopus 로고    scopus 로고
    • Apolipoprotein e genotype and response of carbon monoxide poisoning to hyperbaric oxygen treatment
    • Hopkins RO, Weaver LK, Valentine KJ, et al: Apolipoprotein E genotype and response of carbon monoxide poisoning to hyperbaric oxygen treatment. Am J Respir Crit Care Med 2007; 176:1001-1006
    • (2007) Am J Respir Crit Care Med , vol.176 , pp. 1001-1006
    • Hopkins, R.O.1    Weaver, L.K.2    Valentine, K.J.3
  • 46
    • 56749177589 scopus 로고    scopus 로고
    • Ischemic stroke subtypes and their genetic basis: A comprehensive meta-analysis of small and large vessel stroke
    • Rao R, Tah V, Casas JP, et al: Ischemic stroke subtypes and their genetic basis: a comprehensive meta-analysis of small and large vessel stroke. Eur Neurol 2009; 61:76-86
    • (2009) Eur Neurol , vol.61 , pp. 76-86
    • Rao, R.1    Tah, V.2    Casas, J.P.3
  • 47
    • 67349212184 scopus 로고    scopus 로고
    • BuChE-K and APOE epsilon4 allele frequencies in Lewy body dementias, and influence of genotype and hyperhomocysteinemia on cognitive decline
    • Lane R, He Y, Morris C, et al: BuChE-K and APOE epsilon4 allele frequencies in Lewy body dementias, and influence of genotype and hyperhomocysteinemia on cognitive decline. Mov Disord 2009; 24:392-400
    • (2009) Mov Disord , vol.24 , pp. 392-400
    • Lane, R.1    He, Y.2    Morris, C.3
  • 48
    • 55749096543 scopus 로고    scopus 로고
    • Lack of association of APOE and tau polymorphisms with dementia in Parkinson's disease
    • Ezquerra M, Campdelacreu J, Gaig C, et al: Lack of association of APOE and tau polymorphisms with dementia in Parkinson's disease. Neurosci Lett 2008; 448:20-23
    • (2008) Neurosci Lett , vol.448 , pp. 20-23
    • Ezquerra, M.1    Campdelacreu, J.2    Gaig, C.3
  • 49
    • 50049096429 scopus 로고    scopus 로고
    • Association of APOE with age at onset of sporadic amyotrophic lateral sclerosis
    • Zetterberg H, Jacobsson J, Rosengren L, et al: Association of APOE with age at onset of sporadic amyotrophic lateral sclerosis. J Neurol Sci 2008; 273:67-69
    • (2008) J Neurol Sci , vol.273 , pp. 67-69
    • Zetterberg, H.1    Jacobsson, J.2    Rosengren, L.3
  • 51
    • 41449115503 scopus 로고    scopus 로고
    • Meta-analysis of APOE4 allele and outcome after traumatic brain injury
    • DOI 10.1089/neu.2007.0489
    • Zhou W, Xu D, Peng X, et al: Meta-analysis of APOE4 allele and outcome after traumatic brain injury. J Neurotrauma 2008; 25:279-290 (Pubitemid 351457767)
    • (2008) Journal of Neurotrauma , vol.25 , Issue.4 , pp. 279-290
    • Zhou, W.1    Xu, D.2    Peng, X.3    Zhang, Q.4    Jia, J.5    Crutcher, K.A.6
  • 52
    • 33646712168 scopus 로고    scopus 로고
    • APOE epsilon variation in multiple sclerosis susceptibility and disease severity: Some answers
    • Burwick RM, Ramsay PP, Haines JL, et al: APOE epsilon variation in multiple sclerosis susceptibility and disease severity: some answers. Neurology 2006; 66:1373-1383
    • (2006) Neurology , vol.66 , pp. 1373-1383
    • Burwick, R.M.1    Ramsay, P.P.2    Haines, J.L.3
  • 53
    • 33745043269 scopus 로고    scopus 로고
    • The association between apolipoprotein e and multiple sclerosis
    • Pinholt M, Frederiksen JL, Christiansen M: The association between apolipoprotein E and multiple sclerosis. Eur J Neurol 2006; 13:573-580
    • (2006) Eur J Neurol , vol.13 , pp. 573-580
    • Pinholt, M.1    Frederiksen, J.L.2    Christiansen, M.3
  • 55
    • 33846530125 scopus 로고    scopus 로고
    • Cognitive impairment in patients with multiple sclerosis: Association with the APOE gene and promoter polymorphisms
    • Parmenter BA, Denney DR, Lynch SG, et al: Cognitive impairment in patients with multiple sclerosis: association with the APOE gene and promoter polymorphisms. Mult Scler 2007; 13:25-32
    • (2007) Mult Scler , vol.13 , pp. 25-32
    • Parmenter, B.A.1    Denney, D.R.2    Lynch, S.G.3
  • 58
    • 77952408511 scopus 로고    scopus 로고
    • Cognitive impairment in multiple sclerosis
    • 2nd ed. Feinstein A. New York, Cambridge University Press
    • Feinstein A: Cognitive impairment in multiple sclerosis, in The Clinical Neuropsychiatry of Multiple Sclerosis, 2nd ed. Feinstein A. New York, Cambridge University Press, 2007, pp 115-144
    • (2007) The Clinical Neuropsychiatry of Multiple Sclerosis , pp. 115-144
    • Feinstein, A.1
  • 59
    • 33847196388 scopus 로고    scopus 로고
    • APOE epsilon4 is associated with impaired verbal learning in patients with MS
    • DOI 10.1212/01.wnl.0000254468.51973.44, PII 0000611420070220000006
    • Koutsis G, Panas M, Giogkaraki E, et al: APOE epsilon4 is associated with impaired verbal learning in patients with MS. Neurology 2007; 68:546-549 (Pubitemid 46303599)
    • (2007) Neurology , vol.68 , Issue.8 , pp. 546-549
    • Koutsis, G.1    Panas, M.2    Giogkaraki, E.3    Potagas, C.4    Karadima, G.5    Sfagos, C.6    Vassilopoulos, D.7
  • 61
    • 38149003882 scopus 로고    scopus 로고
    • APOE epsilon 4 allele is associated with cognitive impairment in patients with multiple sclerosis
    • Shi J, Zhao CB, Vollmer TL, et al: APOE epsilon 4 allele is associated with cognitive impairment in patients with multiple sclerosis. Neurology 2008; 70:185-190
    • (2008) Neurology , vol.70 , pp. 185-190
    • Shi, J.1    Zhao, C.B.2    Vollmer, T.L.3
  • 62
    • 43149113935 scopus 로고    scopus 로고
    • Cognitive impairment in relapsing-remitting multiple sclerosis can be predicted by imaging performed several years earlier
    • DOI 10.1177/1352458507082353
    • Summers M, Fisniku L, Anderson V, et al: Cognitive impairment in relapsing-remitting multiple sclerosis can be predicted by imaging performed several years earlier. Mult Scler 2008; 14:197-204 (Pubitemid 351639628)
    • (2008) Multiple Sclerosis , vol.14 , Issue.2 , pp. 197-204
    • Summers, M.M.1    Fisniku, L.K.2    Anderson, V.M.3    Miller, D.H.4    Cipolotti, L.5    Ron, M.A.6
  • 63
    • 3142548975 scopus 로고    scopus 로고
    • Posterior fossa lesion volume and slowed information processing in multiple sclerosis
    • DOI 10.1093/brain/awh167
    • Archibald CJ, Wei X, Scott JN, et al: Posterior fossa lesion volume and slowed information processing in multiple sclerosis. Brain 2004; 127:1526-1534 (Pubitemid 38899406)
    • (2004) Brain , vol.127 , Issue.7 , pp. 1526-1534
    • Archibald, C.J.1    Wei, X.2    Scott, J.N.3    Wallace, C.J.4    Zhang, Y.5    Metz, L.M.6    Mitchell, J.R.7
  • 66
    • 33746547762 scopus 로고    scopus 로고
    • Cognitive impairment is associated with subcortical magnetic resonance imaging grey matter T2 hypointensity in multiple sclerosis
    • DOI 10.1191/135248506ms1301oa
    • Brass SD, Benedict RH, Weinstock-Guttman B, et al: Cognitive impairment is associated with subcortical magnetic resonance imaging grey matter T2 hypointensity in multiple sclerosis. Mult Scler 2006; 12:437-444 (Pubitemid 44132584)
    • (2006) Multiple Sclerosis , vol.12 , Issue.4 , pp. 437-444
    • Brass, S.D.1    Benedict, R.H.B.2    Weinstock-Guttman, B.3    Munschauer, F.4    Bakshi, R.5
  • 68
    • 33645842780 scopus 로고    scopus 로고
    • Gray and white matter brain atrophy and neuropsychological impairment in multiple sclerosis
    • DOI 10.1212/01.wnl.0000201238.93586.d9, PII 0000611420060314000015
    • Sanfilipo MP, Benedict RH, Weinstock-Guttman B, et al: Gray and white matter brain atrophy and neuropsychological impairment in multiple sclerosis. Neurology 2006; 66:685-692 (Pubitemid 43739822)
    • (2006) Neurology , vol.66 , Issue.5 , pp. 685-692
    • Sanfilipo, M.P.1    Benedict, R.H.B.2    Weinstock-Guttman, B.3    Bakshi, R.4
  • 69
    • 60249098231 scopus 로고    scopus 로고
    • Memory impairment in multiple sclerosis: Correlation with deep grey matter and mesial temporal atrophy
    • Benedict RH, Ramasamy D, Munschauer F, et al: Memory impairment in multiple sclerosis: correlation with deep grey matter and mesial temporal atrophy. J Neurol Neurosurg Psychiatry 2009; 80:201-206
    • (2009) J Neurol Neurosurg Psychiatry , vol.80 , pp. 201-206
    • Benedict, R.H.1    Ramasamy, D.2    Munschauer, F.3
  • 70
    • 58149191208 scopus 로고    scopus 로고
    • Characteristics of neurological and cognitive status in patients with multiple sclerosis in relation to the location and volumes of demyelination foci and the severity of brain atrophy
    • Mineev KK, Prakhova LN, Il'ves AG, et al: Characteristics of neurological and cognitive status in patients with multiple sclerosis in relation to the location and volumes of demyelination foci and the severity of brain atrophy. Neurosci Behav Physiol 2009; 39:35-38
    • (2009) Neurosci Behav Physiol , vol.39 , pp. 35-38
    • Mineev, K.K.1    Prakhova, L.N.2    Il'ves, A.G.3
  • 71
    • 41149116636 scopus 로고    scopus 로고
    • Use of combined conventional and quantitative MRI to quantify pathology related to cognitive impairment in multiple sclerosis
    • DOI 10.1136/jnnp.2006.112177
    • Lin X, Tench CR, Morgan PS, Constantinescu CS: Use of combined conventional and quantitative MRI to quantify pathology related to cognitive impairment in multiple sclerosis. J Neurol Neurosurg Psychiatry 2008; 79:437-441 (Pubitemid 351441502)
    • (2008) Journal of Neurology, Neurosurgery and Psychiatry , vol.79 , Issue.4 , pp. 437-441
    • Lin, X.1    Tench, C.R.2    Morgan, P.S.3    Constantinescu, C.S.4
  • 72
    • 39449133109 scopus 로고    scopus 로고
    • Recent advances in neuroimaging of multiple sclerosis
    • DOI 10.1055/s-2007-1019127
    • Rashid W, Miller DH: Recent advances in neuroimaging of multiple sclerosis. Semin Neurol 2008; 28:46-55 (Pubitemid 351273083)
    • (2008) Seminars in Neurology , vol.28 , Issue.1 , pp. 46-55
    • Rashid, W.1    Miller, D.H.2
  • 74
    • 30844464790 scopus 로고    scopus 로고
    • The measurement and clinical relevance of brain atrophy in multiple sclerosis
    • DOI 10.1016/S1474-4422(06)70349-0, PII S1474442206703490
    • Bermel RA, Bakshi R: The measurement and clinical relevance of brain atrophy in multiple sclerosis. Lancet Neurol 2006; 5:158-170 (Pubitemid 43107851)
    • (2006) Lancet Neurology , vol.5 , Issue.2 , pp. 158-170
    • Bermel, R.A.1    Bakshi, R.2
  • 76
    • 33646836430 scopus 로고    scopus 로고
    • MRI markers of destructive pathology in multiple sclerosis-related cognitive dysfunction
    • DOI 10.1016/j.jns.2005.07.014, PII S0022510X06001122
    • Rovaris M, Comi G, Filippi M: MRI markers of destructive pathology in multiple sclerosis-related cognitive dysfunction. J Neurol Sci 2006; 245:111-116 (Pubitemid 43775933)
    • (2006) Journal of the Neurological Sciences , vol.245 , Issue.1-2 , pp. 111-116
    • Rovaris, M.1    Comi, G.2    Filippi, M.3
  • 81
    • 0032971730 scopus 로고    scopus 로고
    • Neuronal damage in T1-hypointense multiple sclerosis lesions demonstrated in vivo using proton magnetic resonance spectroscopy
    • DOI 10.1002/1531-8249(199907)46:1<79::AID-ANA12>3.0.CO;2-9
    • van Walderveen MA, Barkhof F, Pouwels PJ, et al: Neuronal damage in T1-hypointense multiple sclerosis lesions demonstrated in vivo using proton magnetic resonance spectroscopy. Ann Neurol 1999; 46:79-87 (Pubitemid 29314385)
    • (1999) Annals of Neurology , vol.46 , Issue.1 , pp. 79-87
    • Van Walderveen, M.A.A.1    Barkhof, F.2    Pouwels, P.J.W.3    Van Schijndel, R.A.4    Polman, C.H.5    Castelijns, J.A.6
  • 86
    • 0035996209 scopus 로고    scopus 로고
    • Disease severity in Danish multiple sclerosis patients evaluated by MRI and three genetic markers (HLA-DRBI*1501, CCR5 deletion mutation, apolipoprotein E)
    • DOI 10.1191/1352458502ms816oa
    • Schreiber K, Otura AB, Ryder LP, et al: Disease severity in Danish multiple sclerosis patients evaluated by MRI and three genetic markers (HLA-DRB1*1501, CCR5 deletion mutation, apolipoprotein E). Mult Scler 2002; 8:295-298 (Pubitemid 34784756)
    • (2002) Multiple Sclerosis , vol.8 , Issue.4 , pp. 295-298
    • Schreiber, K.1    Oturai, A.B.2    Ryder, L.P.3    Madsen, H.O.4    Jorgensen, O.S.5    Svejgaard, A.6    Sorensen, P.S.7
  • 89
    • 33846555710 scopus 로고    scopus 로고
    • Screening for cognitive impairment in multiple sclerosis using the Symbol Digit Modalities Test
    • DOI 10.1177/1352458506070750
    • Parmenter BA, Weinstock-Guttman B, Garg N, et al: Screening for cognitive impairment in multiple sclerosis using the Symbol Digit Modalities Test. Mult Scler 2007; 13:52-57 (Pubitemid 46152761)
    • (2007) Multiple Sclerosis , vol.13 , Issue.1 , pp. 52-57
    • Parmenter, B.A.1    Weinstock-Guttman, B.2    Garg, N.3    Munschauer, F.4    Benedict, R.H.B.5
  • 94
    • 0031585498 scopus 로고    scopus 로고
    • Reduced size of right hippocampus in 39- To 80-year-old normal subjects carrying the apolipoprotein e epsilon4 allele
    • DOI 10.1016/S0304-3940(97)00743-X, PII S030439409700743X
    • Tohgi H, Takahashi S, Kato E, et al: Reduced size of right hippocampus in 39- to 80-year-old normal subjects carrying the apolipoprotein E epsilon4 allele. Neurosci Lett 1997; 236:21-24 (Pubitemid 27492069)
    • (1997) Neuroscience Letters , vol.236 , Issue.1 , pp. 21-24
    • Tohgi, H.1    Takahashi, S.2    Kato, E.3    Homma, A.4    Rie, N.5    Sasaki, K.6    Yonezawa, H.7    Sasaki, M.8
  • 98
    • 1042302759 scopus 로고    scopus 로고
    • Prediction of Neuropsychological Impairment in Multiple Sclerosis: Comparison of Conventional Magnetic Resonance Imaging Measures of Atrophy and Lesion Burden
    • DOI 10.1001/archneur.61.2.226
    • Benedict RH, Weinstock-Guttman B, Fishman I, et al: Prediction of neuropsychological impairment in multiple sclerosis: comparison of conventional magnetic resonance imaging measures of atrophy and lesion burden. Arch Neurol 2004; 61:226-230 (Pubitemid 38197556)
    • (2004) Archives of Neurology , vol.61 , Issue.2 , pp. 226-230
    • Benedict, R.H.B.1    Weinstock-Guttman, B.2    Fishman, I.3    Sharma, J.4    Tjoa, C.W.5    Bakshi, R.6
  • 99
    • 51349164037 scopus 로고    scopus 로고
    • Brain atrophy as a marker of cognitive impairment in mildly disabling relapsing-remitting multiple sclerosis
    • Sanchez MP, Nieto A, Barroso J, et al: Brain atrophy as a marker of cognitive impairment in mildly disabling relapsing-remitting multiple sclerosis. Eur J Neurol 2008; 15:1091-1099
    • (2008) Eur J Neurol , vol.15 , pp. 1091-1099
    • Sanchez, M.P.1    Nieto, A.2    Barroso, J.3
  • 100
    • 33748629908 scopus 로고    scopus 로고
    • Neocortical atrophy, third ventricular width, and cognitive dysfunction in multiple sclerosis
    • Benedict RH, Bruce JM, Dwyer MG, et al: Neocortical atrophy, third ventricular width, and cognitive dysfunction in multiple sclerosis. Arch Neurol 2006; 63:1301-1306
    • (2006) Arch Neurol , vol.63 , pp. 1301-1306
    • Benedict, R.H.1    Bruce, J.M.2    Dwyer, M.G.3
  • 101
    • 33645842780 scopus 로고    scopus 로고
    • Gray and white matter brain atrophy and neuropsychological impairment in multiple sclerosis
    • DOI 10.1212/01.wnl.0000201238.93586.d9, PII 0000611420060314000015
    • Sanfilipo MP, Benedict RH, Weinstock-Guttman B, et al: Gray and white matter brain atrophy and neuropsychological impairment in multiple sclerosis. Neurology 2006; 66:685-692 (Pubitemid 43739822)
    • (2006) Neurology , vol.66 , Issue.5 , pp. 685-692
    • Sanfilipo, M.P.1    Benedict, R.H.B.2    Weinstock-Guttman, B.3    Bakshi, R.4
  • 102
    • 30844464790 scopus 로고    scopus 로고
    • The measurement and clinical relevance of brain atrophy in multiple sclerosis
    • DOI 10.1016/S1474-4422(06)70349-0, PII S1474442206703490
    • Bermel RA, Bakshi R: The measurement and clinical relevance of brain atrophy in multiple sclerosis. Lancet Neurol 2006; 5:158-170 (Pubitemid 43107851)
    • (2006) Lancet Neurology , vol.5 , Issue.2 , pp. 158-170
    • Bermel, R.A.1    Bakshi, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.