-
1
-
-
84903279290
-
Islet cell transplantation for the treatment of type 1 diabetes: Recent advances and future challenges
-
Bruni, A., Gala-Lopez, B., Pepper, A. R., Abualhassan, N. S. & Shapiro, A. J. Islet cell transplantation for the treatment of type 1 diabetes: Recent advances and future challenges. Diabetes Metab. Syndr. Obes. 7, 211-223 (2014).
-
(2014)
Diabetes Metab. Syndr. Obes
, vol.7
, pp. 211-223
-
-
Bruni, A.1
Gala-Lopez, B.2
Pepper, A.R.3
Abualhassan, N.S.4
Shapiro, A.J.5
-
2
-
-
0034721255
-
Islet transplantation in seven patientswith type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen
-
Shapiro, A. M. et al. Islet transplantation in seven patientswith type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N. Engl. J. Med. 343, 230-238 (2000).
-
(2000)
N. Engl. J. Med
, vol.343
, pp. 230-238
-
-
Shapiro, A.M.1
-
3
-
-
21344462346
-
Five-year follow-up after clinical islet transplantation
-
Ryan, E. A. et al. Five-year follow-up after clinical islet transplantation. Diabetes 54, 2060-2069 (2005).
-
(2005)
Diabetes
, vol.54
, pp. 2060-2069
-
-
Ryan, E.A.1
-
4
-
-
84863719097
-
Caspase inhibitor idn6556 facilitates marginal mass islet engraftment in a porcine islet autotransplant model
-
McCall, M. D. et al. Caspase inhibitor IDN6556 facilitates marginal mass islet engraftment in a porcine islet autotransplant model. Transplantation 94, 30-35 (2012).
-
(2012)
Transplantation
, vol.94
, pp. 30-35
-
-
McCall, M.D.1
-
5
-
-
0029821899
-
Vulnerability of islets in the immediate posttransplantation period dynamic changes in structure and function
-
Davalli, A. M. et al. Vulnerability of islets in the immediate posttransplantation period. Dynamic changes in structure and function. Diabetes 45, 1161-1167 (1996).
-
(1996)
Diabetes
, vol.45
, pp. 1161-1167
-
-
Davalli, A.M.1
-
6
-
-
0036097472
-
Beta-cell death and mass in syngeneically transplanted islets exposed to short-And long-term hyperglycemia
-
Biarnes, M. et al. Beta-cell death and mass in syngeneically transplanted islets exposed to short-And long-term hyperglycemia. Diabetes 51, 66-72 (2002).
-
(2002)
Diabetes
, vol.51
, pp. 66-72
-
-
Biarnes, M.1
-
7
-
-
34248190170
-
Caspase inhibitor therapy enhances marginal mass islet graft survival and preserves long-term function in islet transplantation
-
Emamaullee, J. A., Stanton, L., Schur, C. & Shapiro, A. M. Caspase inhibitor therapy enhances marginal mass islet graft survival and preserves long-term function in islet transplantation. Diabetes 56, 1289-1298 (2007).
-
(2007)
Diabetes
, vol.56
, pp. 1289-1298
-
-
Emamaullee, J.A.1
Stanton, L.2
Schur, C.3
Shapiro, A.M.4
-
8
-
-
84922394053
-
Regulated cell death and inflammation: An auto-Amplification loop causes organ failure
-
Linkermann, A., Stockwell, B. R., Krautwald, S. & Anders, H. J. Regulated cell death and inflammation: An auto-Amplification loop causes organ failure. Nat. Rev. Immunol. 14, 759-767 (2014).
-
(2014)
Nat. Rev. Immunol
, vol.14
, pp. 759-767
-
-
Linkermann, A.1
Stockwell, B.R.2
Krautwald, S.3
Anders, H.J.4
-
9
-
-
84973125781
-
Nonapoptotic cell death in acute kidney injury and transplantation
-
Linkermann, A. Nonapoptotic cell death in acute kidney injury and transplantation. Kidney Int. 89, 46-57 (2016).
-
(2016)
Kidney Int
, vol.89
, pp. 46-57
-
-
Linkermann, A.1
-
10
-
-
84922602504
-
Necroptosis and its role in inflammation
-
Pasparakis, M. & Vandenabeele, P. Necroptosis and its role in inflammation. Nature 517, 311-320 (2015).
-
(2015)
Nature
, vol.517
, pp. 311-320
-
-
Pasparakis, M.1
Vandenabeele, P.2
-
11
-
-
84963543290
-
Programmed necrosis in inflammation: Toward identification of the effector molecules
-
Wallach, D., Kang, T. B., Dillon, C. P. & Green, D. R. Programmed necrosis in inflammation: Toward identification of the effector molecules. Science 352, aaf2154 (2016).
-
(2016)
Science
, vol.352
, pp. aaf2154
-
-
Wallach, D.1
Kang, T.B.2
Dillon, C.P.3
Green, D.R.4
-
12
-
-
67649373025
-
Il-1beta receptor blockade protects islets against proinflammatory cytokine induced necrosis and apoptosis
-
Schwarznau, A. et al. IL-1beta receptor blockade protects islets against proinflammatory cytokine induced necrosis and apoptosis. J. Cell. Physiol. 220, 341-347 (2009).
-
(2009)
J. Cell. Physiol
, vol.220
, pp. 341-347
-
-
Schwarznau, A.1
-
13
-
-
84876500957
-
Withaferin a inhibits pro-inflammatory cytokine-induced damage to islets in culture and following transplantation
-
SoRelle, J. A. et al. Withaferin A inhibits pro-inflammatory cytokine-induced damage to islets in culture and following transplantation. Diabetologia 56, 814-824 (2013).
-
(2013)
Diabetologia
, vol.56
, pp. 814-824
-
-
SoRelle, J.A.1
-
14
-
-
48249151829
-
The caspase selective inhibitor ep1013 augments human islet graft function and longevity in marginal mass islet transplantation in mice
-
Emamaullee, J. A. et al. The caspase selective inhibitor EP1013 augments human islet graft function and longevity in marginal mass islet transplantation in mice. Diabetes 57, 1556-1566 (2008).
-
(2008)
Diabetes
, vol.57
, pp. 1556-1566
-
-
Emamaullee, J.A.1
-
15
-
-
84899764816
-
Sod therapeutics: Latest insights into their structureactivity relationships and impact on the cellular redox-based signaling pathways
-
Batinic-Haberle, I. et al. SOD therapeutics: Latest insights into their structureactivity relationships and impact on the cellular redox-based signaling pathways. Antioxid. Redox Signal. 20, 2372-2415 (2014).
-
(2014)
Antioxid. Redox Signal
, vol.20
, pp. 2372-2415
-
-
Batinic-Haberle, I.1
-
16
-
-
79959364964
-
The caspase inhibitor idn-6556 (pf3491390) improves marginal mass engraftment after islet transplantation in mice
-
McCall, M. et al. The caspase inhibitor IDN-6556 (PF3491390) improves marginal mass engraftment after islet transplantation in mice. Surgery 150, 48-55 (2011).
-
(2011)
Surgery
, vol.150
, pp. 48-55
-
-
McCall, M.1
-
17
-
-
84913582286
-
Synchronized renal tubular cell death involves ferroptosis
-
Linkermann, A. et al. Synchronized renal tubular cell death involves ferroptosis. Proc. Natl. Acad. Sci. USA 111, 16836-16841 (2014).
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 16836-16841
-
-
Linkermann, A.1
-
18
-
-
84861541814
-
Ferroptosis: An iron-dependent form of nonapoptotic cell death
-
Dixon, S. J. et al. Ferroptosis: An iron-dependent form of nonapoptotic cell death. Cell 149, 1060-1072 (2012).
-
(2012)
Cell
, vol.149
, pp. 1060-1072
-
-
Dixon, S.J.1
-
19
-
-
85030552365
-
Ferroptosis: A regulated cell death nexus linking metabolism, redox biology, and disease
-
Stockwell, B. R. et al. Ferroptosis: A regulated cell death nexus linking metabolism, redox biology, and disease. Cell 171, 273-285 (2017).
-
(2017)
Cell
, vol.171
, pp. 273-285
-
-
Stockwell, B.R.1
-
20
-
-
84958103915
-
Ferroptosis: Death by lipid peroxidation
-
Yang, W. S. & Stockwell, B. R. Ferroptosis: Death by lipid peroxidation. Trends Cell Biol. 26, 165-176 (2016).
-
(2016)
Trends Cell Biol
, vol.26
, pp. 165-176
-
-
Yang, W.S.1
Stockwell, B.R.2
-
21
-
-
84890922670
-
The role of iron and reactive oxygen species in cell death
-
Dixon, S. J. & Stockwell, B. R. The role of iron and reactive oxygen species in cell death. Nat. Chem. Biol. 10, 9-17 (2014).
-
(2014)
Nat. Chem. Biol
, vol.10
, pp. 9-17
-
-
Dixon, S.J.1
Stockwell, B.R.2
-
22
-
-
84861535833
-
Ironing out cell death mechanisms
-
Reed, J. C. & Pellecchia, M. Ironing out cell death mechanisms. Cell 149, 963-965 (2012).
-
(2012)
Cell
, vol.149
, pp. 963-965
-
-
Reed, J.C.1
Pellecchia, M.2
-
23
-
-
0036328572
-
Preservation of human islet cell functional mass by antioxidative action of a novel sod mimic compound
-
Bottino, R. et al. Preservation of human islet cell functional mass by antioxidative action of a novel SOD mimic compound. Diabetes 51, 2561-2567 (2002).
-
(2002)
Diabetes
, vol.51
, pp. 2561-2567
-
-
Bottino, R.1
-
24
-
-
4644233237
-
Response of human islets to isolation stress and the effect of antioxidant treatment
-
Bottino, R. et al. Response of human islets to isolation stress and the effect of antioxidant treatment. Diabetes 53, 2559-2568 (2004).
-
(2004)
Diabetes
, vol.53
, pp. 2559-2568
-
-
Bottino, R.1
-
25
-
-
84897059782
-
Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models
-
Skouta, R. et al. Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models. J. Am. Chem. Soc. 136, 4551-4556 (2014).
-
(2014)
J. Am. Chem. Soc
, vol.136
, pp. 4551-4556
-
-
Skouta, R.1
-
26
-
-
0034495258
-
Oxidative stress increases potassium efflux from pancreatic islets by depletion of intracellular calcium stores
-
Hennige, A. M., Lembert, N., Wahl, M. A. & Ammon, H. P. Oxidative stress increases potassium efflux from pancreatic islets by depletion of intracellular calcium stores. Free. Radic. Res. 33, 507-516 (2000).
-
(2000)
Free. Radic. Res
, vol.33
, pp. 507-516
-
-
Hennige, A.M.1
Lembert, N.2
Wahl, M.A.3
Ammon, H.P.4
-
27
-
-
0034464215
-
Inhibition of glucose-induced insulin secretion by 4-hydroxy-2-nonenal and other lipid peroxidation products
-
Miwa, I., Ichimura, N., Sugiura, M., Hamada, Y. & Taniguchi, S. Inhibition of glucose-induced insulin secretion by 4-hydroxy-2-nonenal and other lipid peroxidation products. Endocrinology 141, 2767-2772 (2000).
-
(2000)
Endocrinology
, vol.141
, pp. 2767-2772
-
-
Miwa, I.1
Ichimura, N.2
Sugiura, M.3
Hamada, Y.4
Taniguchi, S.5
-
28
-
-
84880144523
-
Overexpression of glutathione peroxidase 4 prevents betacell dysfunction induced by prolonged elevation of lipids in vivo
-
Koulajian, K. et al. Overexpression of glutathione peroxidase 4 prevents betacell dysfunction induced by prolonged elevation of lipids in vivo. Am. J. Physiol. Endocrinol. Metab. 305, E254-E262 (2013).
-
(2013)
Am. J. Physiol. Endocrinol. Metab
, vol.305
, pp. E254-E262
-
-
Koulajian, K.1
-
29
-
-
0032053707
-
Oxygen radicals and signaling
-
Finkel, T. Oxygen radicals and signaling. Curr. Opin. Cell Biol. 10, 248-253 (1998).
-
(1998)
Curr. Opin. Cell Biol
, vol.10
, pp. 248-253
-
-
Finkel, T.1
-
30
-
-
84873709467
-
Glutathione ethyl ester supplementation during pancreatic islet isolation improves viability and transplant outcomes in a murine marginal islet mass model
-
do Amaral, A. S. et al. Glutathione ethyl ester supplementation during pancreatic islet isolation improves viability and transplant outcomes in a murine marginal islet mass model. PLoS ONE 8, e55288 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e55288
-
-
Do Amaral, A.S.1
-
31
-
-
53149153889
-
Glutamine induces heat-shock protein-70 and glutathione expression and attenuates ischemic damage in rat islets
-
Jang, H. J. et al. Glutamine induces heat-shock protein-70 and glutathione expression and attenuates ischemic damage in rat islets. Transplant. Proc. 40, 2581-2584 (2008).
-
(2008)
Transplant. Proc
, vol.40
, pp. 2581-2584
-
-
Jang, H.J.1
-
32
-
-
33644822242
-
Intra-ductal glutamine administration reduces oxidative injury during human pancreatic islet isolation
-
Avila, J. et al. Intra-ductal glutamine administration reduces oxidative injury during human pancreatic islet isolation. Am. J. Transplant. 5, 2830-2837 (2005).
-
(2005)
Am. J. Transplant
, vol.5
, pp. 2830-2837
-
-
Avila, J.1
-
33
-
-
1542374749
-
Insulin secretion profiles are modified by overexpression of glutamate dehydrogenase in pancreatic islets
-
Carobbio, S. et al. Insulin secretion profiles are modified by overexpression of glutamate dehydrogenase in pancreatic islets. Diabetologia 47, 266-276 (2004).
-
(2004)
Diabetologia
, vol.47
, pp. 266-276
-
-
Carobbio, S.1
-
34
-
-
11144354786
-
A signaling role of glutamine in insulin secretion
-
Li, C. et al. A signaling role of glutamine in insulin secretion. J. Biol. Chem. 279, 13393-13401 (2004).
-
(2004)
J. Biol. Chem
, vol.279
, pp. 13393-13401
-
-
Li, C.1
-
35
-
-
0842284799
-
Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes
-
Robertson, R. P., Harmon, J., Tran, P. O. & Poitout, V. Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes. Diabetes 53(Suppl 1), S119-S124 (2004).
-
(2004)
Diabetes
, vol.53
, pp. S119-S124
-
-
Robertson, R.P.1
Harmon, J.2
Tran, P.O.3
Poitout, V.4
-
36
-
-
85009170696
-
Engraftment site and effectiveness of the pan-caspase inhibitor f573 to improve engraftment in mouse and human islet transplantation in mice
-
Pepper, A. R. et al. Engraftment site and effectiveness of the pan-caspase inhibitor F573 to improve engraftment in mouse and human islet transplantation in mice. Transplantation 101, 2321-2329 (2017).
-
(2017)
Transplantation
, vol.101
, pp. 2321-2329
-
-
Pepper, A.R.1
-
37
-
-
53749091127
-
Risk factors for islet loss during culture prior to transplantation
-
Kin, T. et al. Risk factors for islet loss during culture prior to transplantation. Transpl. Int. 21, 1029-1035 (2008).
-
(2008)
Transpl. Int
, vol.21
, pp. 1029-1035
-
-
Kin, T.1
|