메뉴 건너뛰기




Volumn 5, Issue 1, 2018, Pages 110-124

Heavy Metal Exposure and Metabolic Syndrome: Evidence from Human and Model System Studies

Author keywords

Cadmium; Diabetes; Heavy metals; Mercury; Metabolic syndrome; Pb

Indexed keywords

CADMIUM; HEAVY METAL; LEAD; MERCURY;

EID: 85047528098     PISSN: None     EISSN: 21965412     Source Type: Journal    
DOI: 10.1007/s40572-018-0182-3     Document Type: Review
Times cited : (129)

References (70)
  • 1
    • 84897522177 scopus 로고    scopus 로고
    • A comprehensive review on metabolic syndrome
    • PID: 24711954
    • Kaur J. A comprehensive review on metabolic syndrome. Cardiol Res Pract. 2014;2014:943162.
    • (2014) Cardiol Res Pract , vol.2014 , pp. 943162
    • Kaur, J.1
  • 2
    • 84929501636 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome in the United States, 2003-2012
    • COI: 1:CAS:528:DC%2BC2MXhtFyrsbzL, PID: 25988468
    • Aguilar M, Bhuket T, Torres S, Liu B, Wong RJ. Prevalence of the metabolic syndrome in the United States, 2003-2012. JAMA. 2015;313(19):1973–4.
    • (2015) JAMA , vol.313 , Issue.19 , pp. 1973-1974
    • Aguilar, M.1    Bhuket, T.2    Torres, S.3    Liu, B.4    Wong, R.J.5
  • 3
    • 84988904805 scopus 로고    scopus 로고
    • Prevalence of obesity among adults and youth: United States, 2011-2014
    • Ogden CL, Carroll MD, Fryar CD, Flegal KM. Prevalence of obesity among adults and youth: United States, 2011-2014. NCHS Data Brief. 2015;219:1–8.
    • (2015) NCHS Data Brief , vol.219 , pp. 1-8
    • Ogden, C.L.1    Carroll, M.D.2    Fryar, C.D.3    Flegal, K.M.4
  • 4
    • 85016163070 scopus 로고    scopus 로고
    • Early-life chemical exposures and risk of metabolic syndrome
    • De Long NE, Holloway AC. Early-life chemical exposures and risk of metabolic syndrome. Diabetes Metab Syndr Obes. 2017;10:101–9. 10.2147/DMSO.S95296.
    • (2017) Diabetes Metab Syndr Obes , vol.10 , pp. 101-109
    • De Long, N.E.1    Holloway, A.C.2
  • 5
    • 84862017941 scopus 로고    scopus 로고
    • Role of environmental chemicals in diabetes and obesity: a National Toxicology Program workshop review
    • Thayer KA, Heindel JJ, Bucher JR, Gallo MA. Role of environmental chemicals in diabetes and obesity: a National Toxicology Program workshop review. Environ Health Perspect. 2012;120(6):779–89. 10.1289/ehp.1104597.
    • (2012) Environ Health Perspect , vol.120 , Issue.6 , pp. 779-789
    • Thayer, K.A.1    Heindel, J.J.2    Bucher, J.R.3    Gallo, M.A.4
  • 6
    • 85018745381 scopus 로고    scopus 로고
    • Is mercury exposure causing diabetes, metabolic syndrome and insulin resistance? A systematic review of the literature
    • Roy C, Tremblay PY, Ayotte P. Is mercury exposure causing diabetes, metabolic syndrome and insulin resistance? A systematic review of the literature. Environ Res. 2017;156:747–60. 10.1016/j.envres.2017.04.038.
    • (2017) Environ Res , vol.156 , pp. 747-760
    • Roy, C.1    Tremblay, P.Y.2    Ayotte, P.3
  • 8
    • 85013630727 scopus 로고    scopus 로고
    • Association of urinary cadmium with risk of diabetes: a meta-analysis
    • COI: 1:CAS:528:DC%2BC2sXjslWis74%3D, PID: 28233200
    • Li Y, Zhang Y, Wang W, Wu Y. Association of urinary cadmium with risk of diabetes: a meta-analysis. Environ Sci Pollut Res Int. 2017;24(11):10083–90.
    • (2017) Environ Sci Pollut Res Int , vol.24 , Issue.11 , pp. 10083-10090
    • Li, Y.1    Zhang, Y.2    Wang, W.3    Wu, Y.4
  • 9
    • 84888987816 scopus 로고    scopus 로고
    • Environmental chemicals and type 2 diabetes: an updated systematic review of the epidemiologic evidence
    • Kuo CC, Moon K, Thayer KA, Navas-Acien A. Environmental chemicals and type 2 diabetes: an updated systematic review of the epidemiologic evidence. Curr Diabetes Rep. 2013;13(6):831–49. 10.1007/s11892-013-0432-6.
    • (2013) Curr Diabetes Rep , vol.13 , Issue.6 , pp. 831-849
    • Kuo, C.C.1    Moon, K.2    Thayer, K.A.3    Navas-Acien, A.4
  • 10
    • 84911494813 scopus 로고    scopus 로고
    • Cadmium exposure and incidence of diabetes mellitus—results from the Malmo diet and cancer study
    • Borne Y, Fagerberg B, Persson M, Sallsten G, Forsgard N, Hedblad B, et al. Cadmium exposure and incidence of diabetes mellitus—results from the Malmo diet and cancer study. PLoS One. 2014;9(11):e112277. 10.1371/journal.pone.0112277.
    • (2014) PLoS One , vol.9 , Issue.11
    • Borne, Y.1    Fagerberg, B.2    Persson, M.3    Sallsten, G.4    Forsgard, N.5    Hedblad, B.6
  • 11
    • 84867741640 scopus 로고    scopus 로고
    • Association between maternal blood cadmium during pregnancy and birth weight and the risk of fetal growth restriction: the EDEN mother-child cohort study
    • Menai M, Heude B, Slama R, Forhan A, Sahuquillo J, Charles MA, et al. Association between maternal blood cadmium during pregnancy and birth weight and the risk of fetal growth restriction: the EDEN mother-child cohort study. Reprod Toxicol. 2012;34(4):622–7. 10.1016/j.reprotox.2012.09.002.
    • (2012) Reprod Toxicol , vol.34 , Issue.4 , pp. 622-627
    • Menai, M.1    Heude, B.2    Slama, R.3    Forhan, A.4    Sahuquillo, J.5    Charles, M.A.6    Yazbeck, C.7
  • 12
    • 84856212814 scopus 로고    scopus 로고
    • Progress in cadmium-related health effects in persons with high environmental exposure in northwestern Thailand: a five-year follow-up
    • COI: 1:CAS:528:DC%2BC38XhsFGiur8%3D, PID: 22033168, Prospective study with significant associations between Cd exposure and T2D and HT
    • • Swaddiwudhipong W, Limpatanachote P, Mahasakpan P, Krintratun S, Punta B, Funkhiew T. Progress in cadmium-related health effects in persons with high environmental exposure in northwestern Thailand: a five-year follow-up. Environ Res. 2012;112:194–8. Prospective study with significant associations between Cd exposure and T2D and HT.
    • (2012) Environ Res , vol.112 , pp. 194-198
    • Swaddiwudhipong, W.1    Limpatanachote, P.2    Mahasakpan, P.3    Krintratun, S.4    Punta, B.5    Funkhiew, T.6
  • 13
    • 84892419206 scopus 로고    scopus 로고
    • Serum omega-3 polyunsaturated fatty acids and risk of incident type 2 diabetes in men: the Kuopio ischemic heart disease risk factor study
    • Virtanen JK, Mursu J, Voutilainen S, Uusitupa M, Tuomainen TP. Serum omega-3 polyunsaturated fatty acids and risk of incident type 2 diabetes in men: the Kuopio ischemic heart disease risk factor study. Diabetes Care. 2014;37(1):189–96. 10.2337/dc13-1504.
    • (2014) Diabetes Care , vol.37 , Issue.1 , pp. 189-196
    • Virtanen, J.K.1    Mursu, J.2    Voutilainen, S.3    Uusitupa, M.4    Tuomainen, T.P.5
  • 14
    • 84891851165 scopus 로고    scopus 로고
    • Methylmercury exposure and incident diabetes in U.S. men and women in two prospective cohorts
    • Mozaffarian D, Shi P, Morris JS, Grandjean P, Siscovick DS, Spiegelman D, et al. Methylmercury exposure and incident diabetes in U.S. men and women in two prospective cohorts. Diabetes Care. 2013;36(11):3578–84. 10.2337/dc13-0894.
    • (2013) Diabetes Care , vol.36 , Issue.11 , pp. 3578-3584
    • Mozaffarian, D.1    Shi, P.2    Morris, J.S.3    Grandjean, P.4    Siscovick, D.S.5    Spiegelman, D.6    Hu, F.B.7
  • 16
    • 84878236274 scopus 로고    scopus 로고
    • Mercury exposure in young adulthood and incidence of diabetes later in life: the CARDIA trace element study
    • He K, Xun P, Liu K, Morris S, Reis J, Guallar E. Mercury exposure in young adulthood and incidence of diabetes later in life: the CARDIA trace element study. Diabetes Care. 2013;36(6):1584–9. 10.2337/dc12-1842.
    • (2013) Diabetes Care , vol.36 , Issue.6 , pp. 1584-1589
    • He, K.1    Xun, P.2    Liu, K.3    Morris, S.4    Reis, J.5    Guallar, E.6
  • 17
    • 84857345109 scopus 로고    scopus 로고
    • Prior cadmium exposure improves glucoregulation in diabetic rats but exacerbates effects on metabolic dysregulation, oxidative stress, and hepatic and renal toxicity
    • COI: 1:CAS:528:DC%2BC38XitlGgu70%3D, PID: 22268556
    • Singh PK, Baxi D, Diwedi R, Ramachandran AV. Prior cadmium exposure improves glucoregulation in diabetic rats but exacerbates effects on metabolic dysregulation, oxidative stress, and hepatic and renal toxicity. Drug Chem Toxicol. 2012;35(2):167–77.
    • (2012) Drug Chem Toxicol , vol.35 , Issue.2 , pp. 167-177
    • Singh, P.K.1    Baxi, D.2    Diwedi, R.3    Ramachandran, A.V.4
  • 19
    • 84884716293 scopus 로고    scopus 로고
    • Cadmium modulates adipocyte functions in metallothionein-null mice
    • COI: 1:CAS:528:DC%2BC3sXhs1KjtbvE, PID: 23921151, vivo and vitro study identifying Cd-mediated alterations molecular markers of metabolism and adiposity
    • • Kawakami T, Nishiyama K, Kadota Y, Sato M, Inoue M, Suzuki S. Cadmium modulates adipocyte functions in metallothionein-null mice. Toxicol Appl Pharmacol. 2013;272(3):625–36. In vivo and in vitro study identifying Cd-mediated alterations in molecular markers of metabolism and adiposity.
    • (2013) Toxicol Appl Pharmacol , vol.272 , Issue.3 , pp. 625-636
    • Kawakami, T.1    Nishiyama, K.2    Kadota, Y.3    Sato, M.4    Inoue, M.5    Suzuki, S.6
  • 20
    • 85021876860 scopus 로고    scopus 로고
    • Metabolomics study of cadmium-induced diabetic nephropathy and protective effect of caffeic acid phenethyl ester using UPLC-Q-TOF-MS combined with pattern recognition
    • COI: 1:CAS:528:DC%2BC2sXhtFClu7vO, PID: 28704754
    • Gong P, Chang X, Chen X, Bai X, Wen H, Pi S, et al. Metabolomics study of cadmium-induced diabetic nephropathy and protective effect of caffeic acid phenethyl ester using UPLC-Q-TOF-MS combined with pattern recognition. Environ Toxicol Pharmacol. 2017;54:80–92.
    • (2017) Environ Toxicol Pharmacol , vol.54 , pp. 80-92
    • Gong, P.1    Chang, X.2    Chen, X.3    Bai, X.4    Wen, H.5    Pi, S.6
  • 22
    • 84873557177 scopus 로고    scopus 로고
    • Cadmium induces apoptosis in pancreatic β-cells through a mitochondria-dependent pathway: the role of oxidative stress-mediated c-Jun N-terminal kinase activation
    • COI: 1:CAS:528:DC%2BC3sXjtVSku7g%3D, PID: 23405080
    • Chang K-C, Hsu C-C, Liu S-H, Su C-C, Yen C-C, Lee M-J, et al. Cadmium induces apoptosis in pancreatic β-cells through a mitochondria-dependent pathway: the role of oxidative stress-mediated c-Jun N-terminal kinase activation. PLoS One. 2013;8(2):e54374.
    • (2013) PLoS One , vol.8 , Issue.2
    • Chang, K.-C.1    Hsu, C.-C.2    Liu, S.-H.3    Su, C.-C.4    Yen, C.-C.5    Lee, M.-J.6
  • 23
    • 84994247359 scopus 로고    scopus 로고
    • Lead (Pb) exposure promotes diabetes in obese rodents
    • COI: 1:CAS:528:DC%2BC28XhslKntbzJ, PID: 27908418
    • Tyrrell JB, Hafida S, Stemmer P, Adhami A, Leff T. Lead (Pb) exposure promotes diabetes in obese rodents. J Trace Elem Med Biol. 2017;39:221–6.
    • (2017) J Trace Elem Med Biol , vol.39 , pp. 221-226
    • Tyrrell, J.B.1    Hafida, S.2    Stemmer, P.3    Adhami, A.4    Leff, T.5
  • 26
    • 84943329276 scopus 로고    scopus 로고
    • Effects of combined exposure to lead and high-fat diet on bone quality in juvenile male mice
    • COI: 1:CAS:528:DC%2BC1cXls1Snu7k%3D, PID: 25861094
    • Beier EE, Inzana JA, Sheu T-J, Shu L, Puzas JE, Mooney RA. Effects of combined exposure to lead and high-fat diet on bone quality in juvenile male mice. Environ Health Perspect. 2015;123(10):935–43.
    • (2015) Environ Health Perspect , vol.123 , Issue.10 , pp. 935-943
    • Beier, E.E.1    Inzana, J.A.2    Sheu, T.-J.3    Shu, L.4    Puzas, J.E.5    Mooney, R.A.6
  • 27
    • 84905659626 scopus 로고    scopus 로고
    • Perinatal lead (Pb) exposure results in sex-specific effects on food intake, fat, weight, and insulin response across the murine life-course
    • PID: 25105421
    • Faulk C, Barks A, Sánchez BN, Zhang Z, Anderson OS, Peterson KE, et al. Perinatal lead (Pb) exposure results in sex-specific effects on food intake, fat, weight, and insulin response across the murine life-course. PLoS One. 2014;9(8):e104273.
    • (2014) PLoS One , vol.9 , Issue.8
    • Faulk, C.1    Barks, A.2    Sánchez, B.N.3    Zhang, Z.4    Anderson, O.S.5    Peterson, K.E.6
  • 28
    • 33748311969 scopus 로고    scopus 로고
    • The role of phosphoinositide 3-kinase/Akt signaling in low-dose mercury-induced mouse pancreatic beta-cell dysfunction in vitro and in vivo
    • COI: 1:CAS:528:DC%2BD28XlsF2rtb0%3D, PID: 16731823
    • Chen YW, Huang CF, Tsai KS, Yang RS, Yen CC, Yang CY, et al. The role of phosphoinositide 3-kinase/Akt signaling in low-dose mercury-induced mouse pancreatic beta-cell dysfunction in vitro and in vivo. Diabetes. 2006;55(6):1614–24.
    • (2006) Diabetes , vol.55 , Issue.6 , pp. 1614-1624
    • Chen, Y.W.1    Huang, C.F.2    Tsai, K.S.3    Yang, R.S.4    Yen, C.C.5    Yang, C.Y.6
  • 29
    • 84855417420 scopus 로고    scopus 로고
    • Differential effects of cobalt and mercury on lipid metabolism in the white adipose tissue of high-fat diet-induced obesity mice
    • COI: 1:CAS:528:DC%2BC38XltVGisA%3D%3D, PID: 22019852
    • Kawakami T, Hanao N, Nishiyama K, Kadota Y, Inoue M, Sato M, et al. Differential effects of cobalt and mercury on lipid metabolism in the white adipose tissue of high-fat diet-induced obesity mice. Toxicol Appl Pharmacol. 2012;258(1):32–42.
    • (2012) Toxicol Appl Pharmacol , vol.258 , Issue.1 , pp. 32-42
    • Kawakami, T.1    Hanao, N.2    Nishiyama, K.3    Kadota, Y.4    Inoue, M.5    Sato, M.6
  • 30
    • 84900397184 scopus 로고    scopus 로고
    • Toxicology of cadmium and its damage to mammalian organs
    • Thevenod F, Lee WK. Toxicology of cadmium and its damage to mammalian organs. Met Ions Life Sci. 2013;11:415–90. 10.1007/978-94-007-5179-8_14.
    • (2013) Met Ions Life Sci , vol.11 , pp. 415-490
    • Thevenod, F.1    Lee, W.K.2
  • 31
    • 79954642381 scopus 로고    scopus 로고
    • Advances in metal-induced oxidative stress and human disease
    • Jomova K, Valko M. Advances in metal-induced oxidative stress and human disease. Toxicology. 2011;283(2–3):65–87. 10.1016/j.tox.2011.03.001.
    • (2011) Toxicology , vol.283 , Issue.2-3 , pp. 65-87
    • Jomova, K.1    Valko, M.2
  • 32
    • 77956188782 scopus 로고    scopus 로고
    • The relevance of the individual genetic background for the toxicokinetics of two significant neurodevelopmental toxicants: mercury and lead
    • COI: 1:CAS:528:DC%2BC3cXhtVyrtrfO, PID: 20601101
    • Gundacker C, Gencik M, Hengstschlager M. The relevance of the individual genetic background for the toxicokinetics of two significant neurodevelopmental toxicants: mercury and lead. Mutat Res. 2010;705(2):130–40.
    • (2010) Mutat Res , vol.705 , Issue.2 , pp. 130-140
    • Gundacker, C.1    Gencik, M.2    Hengstschlager, M.3
  • 33
    • 84878662545 scopus 로고    scopus 로고
    • Association of lead, mercury and cadmium with diabetes in the Korean population: the Korea National Health and Nutrition Examination Survey (KNHANES) 2009-2010
    • Moon SS. Association of lead, mercury and cadmium with diabetes in the Korean population: the Korea National Health and Nutrition Examination Survey (KNHANES) 2009-2010. Diabet Med. 2013;30(4):e143–8. 10.1111/dme.12103.
    • (2013) Diabet Med , vol.30 , Issue.4 , pp. e143-e148
    • Moon, S.S.1
  • 34
  • 35
    • 84929453537 scopus 로고    scopus 로고
    • Association of urinary metal profiles with altered glucose levels and diabetes risk: a population-based study in China
    • Feng W, Cui X, Liu B, Liu C, Xiao Y, Lu W, et al. Association of urinary metal profiles with altered glucose levels and diabetes risk: a population-based study in China. PLoS One. 2015;10(4):e0123742. 10.1371/journal.pone.0123742.
    • (2015) PLoS One , vol.10 , Issue.4
    • Feng, W.1    Cui, X.2    Liu, B.3    Liu, C.4    Xiao, Y.5    Lu, W.6    Guo, H.7    He, M.8    Zhang, X.9    Yuan, J.10    Chen, W.11    Wu, T.12
  • 36
    • 84962132750 scopus 로고    scopus 로고
    • Metals in urine and diabetes in U.S. adults
    • Menke A, Guallar E, Cowie CC. Metals in urine and diabetes in U.S. adults. Diabetes. 2016;65(1):164–71. 10.2337/db15-0316.
    • (2016) Diabetes , vol.65 , Issue.1 , pp. 164-171
    • Menke, A.1    Guallar, E.2    Cowie, C.C.3
  • 39
    • 70349575438 scopus 로고    scopus 로고
    • Hair tissue mineral analysis and metabolic syndrome
    • Park SB, Choi SW, Nam AY. Hair tissue mineral analysis and metabolic syndrome. Biol Trace Elem Res. 2009;130(3):218–28. 10.1007/s12011-009-8336-7.
    • (2009) Biol Trace Elem Res , vol.130 , Issue.3 , pp. 218-228
    • Park, S.B.1    Choi, S.W.2    Nam, A.Y.3
  • 40
    • 84872010396 scopus 로고    scopus 로고
    • Blood lead is significantly associated with metabolic syndrome in Korean adults: an analysis based on the Korea National Health and Nutrition Examination Survey (KNHANES), 2008
    • Rhee SY, Hwang YC, Woo JT, Sinn DH, Chin SO, Chon S, et al. Blood lead is significantly associated with metabolic syndrome in Korean adults: an analysis based on the Korea National Health and Nutrition Examination Survey (KNHANES), 2008. Cardiovasc Diabetol. 2013;12(1):9. 10.1186/1475-2840-12-9.
    • (2013) Cardiovasc Diabetol , vol.12 , Issue.1 , pp. 9
    • Rhee, S.Y.1    Hwang, Y.C.2    Woo, J.T.3    Sinn, D.H.4    Chin, S.O.5    Chon, S.6
  • 41
    • 84902248647 scopus 로고    scopus 로고
    • Additive effect of heavy metals on metabolic syndrome in the Korean population: the Korea National Health and Nutrition Examination Survey (KNHANES) 2009-2010
    • Moon SS. Additive effect of heavy metals on metabolic syndrome in the Korean population: the Korea National Health and Nutrition Examination Survey (KNHANES) 2009-2010. Endocrine. 2014;46(2):263–71. 10.1007/s12020-013-0061-5.
    • (2014) Endocrine , vol.46 , Issue.2 , pp. 263-271
    • Moon, S.S.1
  • 42
    • 84873990359 scopus 로고    scopus 로고
    • Cadmium exposure in relation to insulin production, insulin sensitivity and type 2 diabetes: a cross-sectional and prospective study in women
    • Barregard L, Bergstrom G, Fagerberg B. Cadmium exposure in relation to insulin production, insulin sensitivity and type 2 diabetes: a cross-sectional and prospective study in women. Environ Res. 2013;121:104–9. 10.1016/j.envres.2012.11.005.
    • (2013) Environ Res , vol.121 , pp. 104-109
    • Barregard, L.1    Bergstrom, G.2    Fagerberg, B.3
  • 43
    • 84878661719 scopus 로고    scopus 로고
    • Association of blood cadmium level with cardiometabolic risk factors and liver enzymes in a nationally representative sample of adolescents: the CASPIAN-III study
    • PID: 23762083
    • Kelishadi R, Askarieh A, Motlagh ME, Tajadini M, Heshmat R, Ardalan G, et al. Association of blood cadmium level with cardiometabolic risk factors and liver enzymes in a nationally representative sample of adolescents: the CASPIAN-III study. J Environ Public Health. 2013;2013:142856.
    • (2013) J Environ Public Health , vol.2013 , pp. 142856
    • Kelishadi, R.1    Askarieh, A.2    Motlagh, M.E.3    Tajadini, M.4    Heshmat, R.5    Ardalan, G.6
  • 44
    • 78649602312 scopus 로고    scopus 로고
    • An examination of the association of selected toxic metals with total and central obesity indices: NHANES 99-02
    • Padilla MA, Elobeid M, Ruden DM, Allison DB. An examination of the association of selected toxic metals with total and central obesity indices: NHANES 99-02. Int J Environ Res Public Health. 2010;7(9):3332–47. 10.3390/ijerph7093332.
    • (2010) Int J Environ Res Public Health , vol.7 , Issue.9 , pp. 3332-3347
    • Padilla, M.A.1    Elobeid, M.2    Ruden, D.M.3    Allison, D.B.4
  • 45
    • 85015648295 scopus 로고    scopus 로고
    • Association between level of urinary trace heavy metals and obesity among children aged 6-19 years: NHANES 1999-2011
    • Shao W, Liu Q, He X, Liu H, Gu A, Jiang Z. Association between level of urinary trace heavy metals and obesity among children aged 6-19 years: NHANES 1999-2011. Environ Sci Pollut Res Int. 2017;24(12):11573–81. 10.1007/s11356-017-8803-1.
    • (2017) Environ Sci Pollut Res Int , vol.24 , Issue.12 , pp. 11573-11581
    • Shao, W.1    Liu, Q.2    He, X.3    Liu, H.4    Gu, A.5    Jiang, Z.6
  • 46
    • 84964703553 scopus 로고    scopus 로고
    • Low birth weight leads to obesity, diabetes and increased leptin levels in adults: the CoLaus study
    • Jornayvaz FR, Vollenweider P, Bochud M, Mooser V, Waeber G, Marques-Vidal P. Low birth weight leads to obesity, diabetes and increased leptin levels in adults: the CoLaus study. Cardiovasc Diabetol. 2016;15(1):73. 10.1186/s12933-016-0389-2.
    • (2016) Cardiovasc Diabetol , vol.15 , Issue.1 , pp. 73
    • Jornayvaz, F.R.1    Vollenweider, P.2    Bochud, M.3    Mooser, V.4    Waeber, G.5    Marques-Vidal, P.6
  • 47
    • 84867644472 scopus 로고    scopus 로고
    • Birth weight and long-term overweight risk: systematic review and a meta-analysis including 643,902 persons from 66 studies and 26 countries globally
    • Schellong K, Schulz S, Harder T, Plagemann A. Birth weight and long-term overweight risk: systematic review and a meta-analysis including 643,902 persons from 66 studies and 26 countries globally. PLoS One. 2012;7(10):e47776. 10.1371/journal.pone.0047776.
    • (2012) PLoS One , vol.7 , Issue.10
    • Schellong, K.1    Schulz, S.2    Harder, T.3    Plagemann, A.4
  • 49
    • 77954956937 scopus 로고    scopus 로고
    • Correlations of urinary cadmium with hypertension and diabetes in persons living in cadmium-contaminated villages in northwestern Thailand: a population study
    • Swaddiwudhipong W, Mahasakpan P, Limpatanachote P, Krintratun S. Correlations of urinary cadmium with hypertension and diabetes in persons living in cadmium-contaminated villages in northwestern Thailand: a population study. Environ Res. 2010;110(6):612–6. 10.1016/j.envres.2010.06.002.
    • (2010) Environ Res , vol.110 , Issue.6 , pp. 612-616
    • Swaddiwudhipong, W.1    Mahasakpan, P.2    Limpatanachote, P.3    Krintratun, S.4
  • 50
    • 38549119895 scopus 로고    scopus 로고
    • Association of urinary cadmium and myocardial infarction
    • Everett CJ, Frithsen IL. Association of urinary cadmium and myocardial infarction. Environ Res. 2008;106(2):284–6. 10.1016/j.envres.2007.10.009.
    • (2008) Environ Res , vol.106 , Issue.2 , pp. 284-286
    • Everett, C.J.1    Frithsen, I.L.2
  • 51
    • 84975266439 scopus 로고    scopus 로고
    • Interrelation of cadmium, smoking, and cardiovascular disease (from the National Health and Nutrition Examination Survey)
    • Hecht EM, Arheart KL, Lee DJ, Hennekens CH, Hlaing WM. Interrelation of cadmium, smoking, and cardiovascular disease (from the National Health and Nutrition Examination Survey). Am J Cardiol. 2016;118(2):204–9. 10.1016/j.amjcard.2016.04.038.
    • (2016) Am J Cardiol , vol.118 , Issue.2 , pp. 204-209
    • Hecht, E.M.1    Arheart, K.L.2    Lee, D.J.3    Hennekens, C.H.4    Hlaing, W.M.5
  • 52
    • 85007038743 scopus 로고    scopus 로고
    • Trace elements in early phase type 2 diabetes mellitus—a population-based study. The HUNT study in Norway
    • COI: 1:CAS:528:DC%2BC28XitFOhtr%2FN, PID: 28159221
    • Hansen AF, Simic A, Asvold BO, Romundstad PR, Midthjell K, Syversen T, et al. Trace elements in early phase type 2 diabetes mellitus—a population-based study. The HUNT study in Norway. J Trace Elem Med Biol. 2017;40:46–53.
    • (2017) J Trace Elem Med Biol , vol.40 , pp. 46-53
    • Hansen, A.F.1    Simic, A.2    Asvold, B.O.3    Romundstad, P.R.4    Midthjell, K.5    Syversen, T.6
  • 54
    • 84958174698 scopus 로고    scopus 로고
    • Association of urinary metals levels with type 2 diabetes risk in coke oven workers
    • COI: 1:CAS:528:DC%2BC2MXitVSrs7fK, PID: 26689646
    • Liu B, Feng W, Wang J, Li Y, Han X, Hu H, et al. Association of urinary metals levels with type 2 diabetes risk in coke oven workers. Environ Pollut. 2016;210:1–8.
    • (2016) Environ Pollut , vol.210 , pp. 1-8
    • Liu, B.1    Feng, W.2    Wang, J.3    Li, Y.4    Han, X.5    Hu, H.6
  • 55
    • 85012198966 scopus 로고    scopus 로고
    • Association of cadmium with diabetes in middle-aged residents of abandoned metal mines: the first health effect surveillance for residents in abandoned metal mines
    • Son HS, Kim SG, Suh BS, Park DU, Kim DS, Yu SD, et al. Association of cadmium with diabetes in middle-aged residents of abandoned metal mines: the first health effect surveillance for residents in abandoned metal mines. Ann Occup Environ Med. 2015;27(1):20. 10.1186/s40557-015-0071-2.
    • (2015) Ann Occup Environ Med , vol.27 , Issue.1 , pp. 20
    • Son, H.S.1    Kim, S.G.2    Suh, B.S.3    Park, D.U.4    Kim, D.S.5    Yu, S.D.6
  • 56
    • 84975147910 scopus 로고    scopus 로고
    • Blood cadmium in Chinese adults and its relationships with diabetes and obesity
    • Nie X, Wang N, Chen Y, Chen C, Han B, Zhu C, et al. Blood cadmium in Chinese adults and its relationships with diabetes and obesity. Environ Sci Pollut Res Int. 2016;23(18):18714–23. 10.1007/s11356-016-7078-2.
    • (2016) Environ Sci Pollut Res Int , vol.23 , Issue.18 , pp. 18714-18723
    • Nie, X.1    Wang, N.2    Chen, Y.3    Chen, C.4    Han, B.5    Zhu, C.6
  • 57
    • 84940908996 scopus 로고    scopus 로고
    • Association of blood cadmium level with metabolic syndrome after adjustment for confounding by serum ferritin and other factors: 2008-2012 Korean National Health and Nutrition Examination Survey
    • Lee BK, Kim Y. Association of blood cadmium level with metabolic syndrome after adjustment for confounding by serum ferritin and other factors: 2008-2012 Korean National Health and Nutrition Examination Survey. Biol Trace Elem Res. 2016;171(1):6–16. 10.1007/s12011-015-0499-9.
    • (2016) Biol Trace Elem Res , vol.171 , Issue.1 , pp. 6-16
    • Lee, B.K.1    Kim, Y.2
  • 58
    • 84878385593 scopus 로고    scopus 로고
    • Blood cadmium, mercury, and lead and metabolic syndrome in South Korea: 2005-2010 Korean National Health and Nutrition Examination Survey
    • Lee BK, Kim Y. Blood cadmium, mercury, and lead and metabolic syndrome in South Korea: 2005-2010 Korean National Health and Nutrition Examination Survey. Am J Ind Med. 2013;56(6):682–92. 10.1002/ajim.22107.
    • (2013) Am J Ind Med , vol.56 , Issue.6 , pp. 682-692
    • Lee, B.K.1    Kim, Y.2
  • 59
    • 57749116205 scopus 로고    scopus 로고
    • Development and characterization of a novel rat model of type 2 diabetes mellitus: the UC Davis type 2 diabetes mellitus UCD-T2DM rat
    • COI: 1:CAS:528:DC%2BD1cXhsFSntbnJ
    • Cummings BP, Digitale EK, Stanhope KL, Graham JL, Baskin DG, Reed BJ, et al. Development and characterization of a novel rat model of type 2 diabetes mellitus: the UC Davis type 2 diabetes mellitus UCD-T2DM rat. AJP: Regul Integr Comp Physiol. 2008;295(6):R1782–R93.
    • (2008) AJP: Regul Integr Comp Physiol , vol.295 , Issue.6 , pp. R1782-R1193
    • Cummings, B.P.1    Digitale, E.K.2    Stanhope, K.L.3    Graham, J.L.4    Baskin, D.G.5    Reed, B.J.6
  • 60
    • 85009193571 scopus 로고    scopus 로고
    • Alterations of serum trace elements in patients with type 2 diabetes
    • COI: 1:CAS:528:DC%2BC2sXhtlansbc%3D, PID: 28159227
    • Zhang H, Yan C, Yang Z, Zhang W, Niu Y, Li X, et al. Alterations of serum trace elements in patients with type 2 diabetes. J Trace Elem Med Biol. 2017;40:91–6.
    • (2017) J Trace Elem Med Biol , vol.40 , pp. 91-96
    • Zhang, H.1    Yan, C.2    Yang, Z.3    Zhang, W.4    Niu, Y.5    Li, X.6
  • 62
    • 84945119989 scopus 로고    scopus 로고
    • Association between whole blood mercury and glucose intolerance among adult Inuit in Greenland
    • COI: 1:CAS:528:DC%2BC2MXhsl2mtr3P, PID: 26497629
    • Jeppesen C, Valera B, Nielsen NO, Bjerregaard P, Jorgensen ME. Association between whole blood mercury and glucose intolerance among adult Inuit in Greenland. Environ Res. 2015;143(Pt A):192–7.
    • (2015) Environ Res , vol.143 , pp. 192-197
    • Jeppesen, C.1    Valera, B.2    Nielsen, N.O.3    Bjerregaard, P.4    Jorgensen, M.E.5
  • 64
    • 84978511941 scopus 로고    scopus 로고
    • Association between toenail mercury and metabolic syndrome is modified by selenium
    • (,), https://doi.org/10.3390/nu8070424
    • Park K, Seo E. Association between toenail mercury and metabolic syndrome is modified by selenium. Nutrients. 2016;8(7) 10.3390/nu8070424.
    • (2016) Nutrients , vol.8 , Issue.7
    • Park, K.1    Seo, E.2
  • 65
    • 85018663948 scopus 로고    scopus 로고
    • Association between blood mercury level and visceral adiposity in adults
    • Park JS, Ha KH, He K, Kim DJ. Association between blood mercury level and visceral adiposity in adults. Diabetes Metab J. 2017;41(2):113–20. 10.4093/dmj.2017.41.2.113.
    • (2017) Diabetes Metab J , vol.41 , Issue.2 , pp. 113-120
    • Park, J.S.1    Ha, K.H.2    He, K.3    Kim, D.J.4
  • 66
    • 0141507053 scopus 로고    scopus 로고
    • Effects of inorganic HgCl2 on adipogenesis
    • COI: 1:CAS:528:DC%2BD3sXotVCltbY%3D, PID: 12883084
    • Barnes DM, Hanlon PR, Kircher EA. Effects of inorganic HgCl2 on adipogenesis. Toxicol Sci. 2003;75(2):368–77.
    • (2003) Toxicol Sci , vol.75 , Issue.2 , pp. 368-377
    • Barnes, D.M.1    Hanlon, P.R.2    Kircher, E.A.3
  • 67
    • 84902367527 scopus 로고    scopus 로고
    • Analytical considerations in the clinical laboratory assessment of metals
    • Wang RY, Caldwell KL, Jones RL. Analytical considerations in the clinical laboratory assessment of metals. J Med Toxicol. 2014;10(2):232–9. 10.1007/s13181-014-0381-8.
    • (2014) J Med Toxicol , vol.10 , Issue.2 , pp. 232-239
    • Wang, R.Y.1    Caldwell, K.L.2    Jones, R.L.3
  • 68
    • 84875311806 scopus 로고    scopus 로고
    • The relationship between cadmium in kidney and cadmium in urine and blood in an environmentally exposed population
    • Akerstrom M, Barregard L, Lundh T, Sallsten G. The relationship between cadmium in kidney and cadmium in urine and blood in an environmentally exposed population. Toxicol Appl Pharmacol. 2013;268(3):286–93. 10.1016/j.taap.2013.02.009.
    • (2013) Toxicol Appl Pharmacol , vol.268 , Issue.3 , pp. 286-293
    • Akerstrom, M.1    Barregard, L.2    Lundh, T.3    Sallsten, G.4
  • 69
    • 84869007052 scopus 로고    scopus 로고
    • Emerging roles of cadmium and heme oxygenase in type-2 diabetes and cancer susceptibility
    • Satarug S, Moore MR. Emerging roles of cadmium and heme oxygenase in type-2 diabetes and cancer susceptibility. Tohoku J Exp Med. 2012;228(4):267–88. 10.1620/tjem.228.267.
    • (2012) Tohoku J Exp Med , vol.228 , Issue.4 , pp. 267-288
    • Satarug, S.1    Moore, M.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.