Blood cadmium, mercury, and lead and metabolic syndrome in South Korea: 2005-2010 Korean National Health and Nutrition Examination Survey

American Journal of Industrial Medicine

Volumn 56, Issue 6, 2013, Pages 682-692

  Lee, Byung Kook ^a   Kim, Yangho ^b  

^a Soonchunhyang University   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

Author keywords

Cadmium; Lead; Mercury; Metabolic syndrome

Indexed keywords

CADMIUM; LEAD; MERCURY;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BLOOD; COMPARATIVE STUDY; CONFIDENCE INTERVAL; CROSS-SECTIONAL STUDY; FEMALE; HUMAN; MALE; METABOLIC SYNDROME X; MIDDLE AGED; NUTRITION; POLLUTANT; PREVALENCE; RISK; RISK ASSESSMENT; SEX RATIO; SOUTH KOREA;

ADULT; AGE DISTRIBUTION; AGED; CADMIUM; CONFIDENCE INTERVALS; CROSS-SECTIONAL STUDIES; ENVIRONMENTAL POLLUTANTS; FEMALE; HUMANS; LEAD; MALE; MERCURY; METABOLIC SYNDROME X; MIDDLE AGED; NUTRITION SURVEYS; ODDS RATIO; PREVALENCE; REPUBLIC OF KOREA; RISK ASSESSMENT; SEX DISTRIBUTION; YOUNG ADULT;

EID: 84878385593     PISSN: 02713586     EISSN: 10970274     Source Type: Journal    
DOI: 10.1002/ajim.22107     Document Type: Article

References (64)

1. ATSDR. 2008. Toxicological profile for cadmium. Atlanta, GA: Agency for Toxic Substances and Disease Registry.
2. Bell RR, Early JL, Nonavinakere VK, Mallory Z. 1990. Effect of cadmium on blood glucose level in the rat. Toxicol Lett 54:199-205.
3. Bergdahl IA, Ahlqwist M, Barregard L, Björkelund C, Blomstrand A, Skerfving S, Sundh V, Wennberg M, Lissner L. 2012. Mercury in serum predicts low risk of death and myocardial infarction in Gothenburg women. Int Arch Occup Environ Health [Epub ahead of print]. DOI: 10.1007/s00420-012-0746-8.
4. Berglund M, Akesson A, Nermell B, Vahter M. 1994. Intestinal absorption of dietary cadmium in women depends on body iron stores and fiber intake. Environ Health Perspect 102:1058-1066.
5. Centers for Disease Control and Prevention (CDC). 2009. Fourth National Report on Human Exposure to Environmental Chemicals. CDC. Available at: http://www.cdc.gov/exposurereport. Accessed May 24, 2012.
6. Choi AL, Weihe P, Budtz-Jørgensen E, Jørgensen PJ, Salonen JT, Tuomainen TP, Murata K, Nielsen HP, Petersen MS, Askham J, Grandjean P. 2009. Methylmercury exposure and adverse cardiovascular effects in Faroese whaling men. Environ Health Perspect 117:367-372.
7. Den Hond E, Nawrot T, Staessen JA. 2002. The relationship between blood pressure and blood lead in NHANES III. National Health and Nutritional Survey. J Human Hypertens 16:563-568.
8. Dillon HK, Ho MH. 1991. Biological monitoring of exposure to chemicals: Metals. New York: John Wiley & Sons.
9. Dórea JG, de Souza JR, Rodrigues P, Ferrari I, Barbosa AC. 2005. Hair mercury (signature of fish consumption) and cardiovascular risk in Munduruku and Kayabi Indians of Amazonia. Environ Res 97:209-219.
10. Eum KD, Lee MS, Paek D. 2008. Cadmium in blood and hypertension. Sci Total Environ 407:147-153.
11. Ferrannini E, Haffner SM, Mitchell BD, Stern MP. 1991. Hyperinsulinaemia: The key feature of a cardiovascular and metabolic syndrome. Diabetologia 34:416-422.
12. Fillion M, Mergler D, Passos CJS, Larribe F, Lemire M, Guimarães JRD. 2006. A preliminary study of mercury exposure and blood pressure in the Brazilian Amazon. Environ Health 5:29. DOI: 10.1186/1476-069X-5-29.
13. Finch NC, Syme HM, Elliott J. 2012. Association of urinary cadmium excretion with feline hypertension. Vet Rec 170:125.
14. Gallagher CM, Meliker JR. 2010. Blood and urine cadmium, blood pressure, and hypertension: A systematic review and meta-analysis. Environ Health Perspect 118:1676-1684.
15. Ghafghazi T, Mennear JH. 1975. The inhibitory effect of cadmium on the secretory activity of the isolated perfused rat pancreas. Toxicol Appl Pharmacol 31:134-142.
16. He K. 2009. Fish, long-chain omega-3 polyunsaturated fatty acids and prevention of cardiovascular disease-Eat fish or take fish oil supplement? Prog Cardiovasc Dis 52:95-114.
17. Ikeda M, Zhang ZW, Shimbo S, Watanabe T, Nakatsuka H, Moon CS, Matsuda-Inoguchi N, Higashikawa K. 2000. Urban population exposure to lead and cadmium in East and Southeast Asia. Sci Total Environ 249:373-384.
18. Ithakissios DS, Ghafghazi T, Mennear JH, Kessler WV. 1975. Effect of multiple doses of cadmium on glucose metabolism and insulin secretion in the rat. Toxicol Appl Pharmacol 31:143-149.
19. Järup L. 2003. Hazards of heavy metal contamination. Br Med Bull 68:167-182.
20. Järup L, Åkesson A. 2009. Current status of cadmium as an environmental health problem. Toxicol Appl Pharmacol 238:201-208.
21. Järup L, Berglund M, Elinder CG, Nordberg G, Vahter M. 1998. Health effects of cadmium exposure-A review of the literature and a risk estimate. Scand J Work Environ Health 24(Suppl 1):1-51.
22. Jeong HS, Lee DB, Cho YC. 1991. A study on the blood lead and cadmium concentration levels of rural residents. Res Rep Environ Sci Tech Chungnam Univ 9:61-73.
23. Kaplan NM. 1989. The deadly quartet: Upper body obesity, glucose intolerance, hypertriglyceridemia, and hypertension. Arch Intern Med 149:1514-1520.
24. Kawakami T, Sugimoto H, Furuichi R, Kadota Y, Inoue M, Setsu K, Suzuki S, Sato M. 2010. Cadmium reduces adipocyte size and expression levels of adiponectin and Peg1/Mest in adipose tissue. Toxicology 267:20-26.
25. Kim K. 2012. Blood cadmium concentration and lipid profile in Korean adults. Environ Res 112:225-229.
26. Kim NS, Lee BK. 2011. National estimates of blood lead, cadmium, and mercury levels in the Korean general adult population. Int Arch Occup Environ Health 84:53-63.
27. Korean Ministry of Health and Welfare. 2007. The Fourth Korean National Health and Nutrition Examination Survey. Seoul: Korean Ministry of Health and Welfare.
28. Korean Ministry of Environment. 2005. Seoul: Report on the study of blood heavy metals of general population. Seoul: Korean Ministry of Environment.
29. Larregle EV, Varas SM, Oliveros LB, Martinez LD, Antón R, Marchevsky E, Giménez MS. 2008. Lipid metabolism in liver of rat exposed to cadmium. Food Chem Toxicol 46:1786-1792.
30. Lee BK. 1999. The role of biological monitoring in the health management of lead-exposed workers. Toxicol Lett 108:149-160.
31. Lee BK, Kim Y. 2012. Iron deficiency is associated with increased levels of blood cadmium in the Korean general population: Analysis of the 2008-2009 Korean National Health and Nutrition Examination Survey data. Environ. Res 112:155-163.
32. Lee MS, Park SK, Hu H, Lee S. 2011. Cadmium exposure and cardiovascular disease in the 2005 Korea National Health and Nutrition Examination Survey. Environ Res 111:171-176.
33. Merali Z, Singhal RL. 1980. Diabetogenic effects of chronic oral cadmium administration to neonatal rats. Br J Pharmacol 69:151-157.
34. Moon CS, Zhang ZW, Shimbo S, Watanabe T, Moon DH, Lee CU, Lee BK, Ahn KD, Lee SH, Ikeda M. 1995. Dietary intake of cadmium and lead among the general population in Korea. Environ Res 71:46-54.
35. Mozaffarian D. 2009. Fish, mercury, selenium and cardiovascular risk: Current evidence and unanswered questions. Int J Environ Res Public Health 6:1894-1916.
36. Mozaffarian D, Rimm EB. 2006. Fish intake, contaminants, and human health: Evaluating the risks and the benefits. JAMA 296:1885-1899.
37. Navas-Acien A, Guallar E, Silbergeld EK, Rothenberg SJ. 2007. Lead exposure and cardiovascular disease-A systematic review. Environ Health Perspect 115:472-482.
38. Nawrot TS, Thjis L, DenHond EM, Roels HA, Staessen JA. 2002. An epidemiological re-appraisal of the association between blood pressure and blood lead: A meta-analysis. J Hum Hypertens 6:123-131.
39. Park JU, Oh SW, Kim SH, Kim YH, Park RJ, Moon JD. 2008. A study on the association between blood lead levels and habitual tobacco and alcohol use in Koreans with no occupational lead exposure. Korean J Occup Environ Med 20:165-173.
40. Perry HM, Jr., Erlanger MW. 1973. Elevated circulating renin activity in rats following doses of cadmium known to induce hypertension. J Lab Clin Med 82:399-405.
41. Perry HM, Jr., Erlanger MW. 1974. Metal-induced hypertension following chronic feeding of low doses of cadmium and mercury. J Lab Clin Med 83:541-547.
42. Perry HM, Jr., Erlanger MW, Perry EF. 1977. Elevated systolic pressure following chronic low-level cadmium feeding. Am J Physiol 232:H114-H121.
43. Prabu SM, Shagirtha K, Renugadevi J. 2010. Amelioration of cadmium-induced oxidative stress, impairment in lipids and plasma lipoproteins by the combined treatment with quercetin and a tocopherol in rats. J Food Sci 75:T132-T140.
44. Prentice RC, Kopp SJ. 1985. Cardiotoxicity of lead at various perfusate calcium concentrations: Functional and metabolic responses of the perfused rat heart. Toxicol Appl Pharmacol 81:491-501.
45. Ramirez DC, Gimenez MS. 2002. Lipid modification in mouse peritoneal macrophages after chronic cadmium exposure. Toxicology 172:1-12.
46. Reaven GM. 1988. Banting Lecture: Role of insulin resistance in human disease. Diabetes 37:1595-1607.
47. Revis NW, Zinsmeister AR, Bull R. 1981. Atherosclerosis and hypertension induction by lead and cadmium ions: An effect prevented by calcium ion. Proc Natl Acad Sci USA 78:6494-6498.
48. Rogalska J, Brzóska MM, Roszczenko A, Moniuszko-Jakoniuk J. 2009. Enhanced zinc consumption prevents cadmium-induced alterations in lipid metabolism in male rats. Chem Biol Interact 177:142-152.
49. Roman HA, Walsh TL, Coull BA, Dewailly E, Guallar E, Hattis D, Mariën K, Schwartz J, Stern AH, Virtanen JK, Rice G. 2011. Evaluation of the cardiovascular effects of methylmercury exposures: Current evidence supports development of a dose-response function for regulatory benefits analysis. Environ Health Perspect 119:607-614.
50. Satarug S, Moore MR. 2004. Adverse health effects of chronic exposure to low-level cadmium in foodstuffs and cigarette smoke. Environ Health Perspect 112:1099-1103.
51. Satarug S, Nishijo M, Ujjin P, Vanavanitkun Y, Moore MR. 2005. Cadmium-induced nephropathy in the development of high blood pressure. Toxicol Lett 157:57-68.
52. Schober SE, Mirel LB, Graubard BI, Brody DJ, Flegal KM. 2006. Blood lead levels and death from all causes, cardiovascular disease, and cancer: Results from the NHANES III Mortality Study. Environ Health Perspect 114:1538-1541.
53. Schwartz GG, Il'yasova D, Ivanova A. 2003. Urinary cadmium, impaired fasting glucose, and diabetes in the NHANES III. Diabetes Care 26:468-470.
54. Scinicariello F, Abadin HG, Murray HE. 2012. Association of low-level blood lead and blood pressure in NHANES 1999-2006. Environ Res 111:1249-1257.
55. Skoczyńska A, Smolik R. 1994. The effect of combined exposure to lead and cadmium on serum lipids and lipid peroxides level in rats. Int J Occup Med Environ Health 7:263-271.
56. Soong YK, Tseng R, Liu C, Lin PW. 1991. Lead, cadmium, arsenic, and mercury levels in maternal and fetal cord blood. J Formos Med Assoc 90:59-65.
57. Sørensen N, Murata K, Budtz-Jorgensen E, Weihe P, Grandjean P. 1999. Prenatal methylmercury exposure as a cardiovascular risk factor at seven years of age. Epidemiology 10:370-375.
58. Staessen J, Bulpitt CJ, Roels H, Bernard A, Fagard R, Joossens JV, Lauwerys R, Lijnen P, Amery A. 1984. Urinary cadmium and lead concentrations and their relation to blood pressure in a population with low exposure. Br J Ind Med 41:241-248.
59. Tellez-Plaza M, Navas-Acien A, Crainiceanu CM, Guallar E. 2008. Cadmium exposure and hypertension in the 1999-2004 National Health and Nutrition Examination Survey (NHANES). Environ Health Perspect 116:51-56.
60. Thun MJ, Osorio AM, Schober S, Hannon WH, Lewis B, Halperin W. 1989. Nephropathy in cadmium workers: Assessment of risk from airborne occupational exposure to cadmium. Br J Ind Med 46:689-697.
61. Valera B, Dewailly E, Poirier P. 2009. Environmental mercury exposure and blood pressure among Nunavik Inuit adults. Hypertension 54:981-986.
62. Virtanen JK, Rissanen TH, Voutilainen S, Tuomainen TP. 2007. Mercury as a risk factor for cardiovascular diseases. J Nutr Biochem 18:75-85.
63. Vupputuri S, Longnecker MP, Daniels JL, Guo X, Sandler DP. 2005. Blood mercury level and blood pressure among US women: Results from the National Health and Nutrition Examination Survey 1999-2000. Environ Res 97:195-200.
64. Zhang ZW, Moon CS, Watanabe T, Shimbo S, He FS, Wu YQ, Zhou SF, Su DM, Qu JB, Ikeda M. 1997. Background exposure of urban populations to lead and cadmium: Comparison between China and Japan. Int Arch Occup Environ Health 69:273-281.