-
2
-
-
85030641230
-
Ceramidesdlipotoxic inducers of metabolic disorders
-
published correction appears
-
ChaurasiaB, SummersSA. Ceramidesdlipotoxic inducers of metabolic disorders [published correction appears in Trends Endocrinol Metab 2018;29:66-67].
-
(2018)
Trends Endocrinol Metab
, vol.29
, pp. 66-67
-
-
Chaurasia, B.1
Summers, S.A.2
-
4
-
-
84903691827
-
Role ofdiacylglycerol activationofPKCuin lipid-induced muscle insulin resistance in humans
-
Szendroedi J, Yoshimura T, Phielix E, et al. Role ofdiacylglycerol activationofPKCuin lipid-induced muscle insulin resistance in humans. Proc Natl Acad Sci U S A 2014;111:9597-9602
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 9597-9602
-
-
Szendroedi, J.1
Yoshimura, T.2
Phielix, E.3
-
5
-
-
84861647226
-
Intrahepatic diacylglycerol content is associated with hepatic insulin resistance in obese subjects
-
e1442
-
Magkos F, Su X, Bradley D, et al. Intrahepatic diacylglycerol content is associated with hepatic insulin resistance in obese subjects. Gastroenterology 2012;142:1444-1446.e1442
-
(2012)
Gastroenterology
, vol.142
, pp. 1444-1446
-
-
Magkos, F.1
Su, X.2
Bradley, D.3
-
6
-
-
80053627289
-
Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease
-
Kumashiro N, ErionDM, Zhang D, et al. Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease. Proc Natl Acad Sci U S A 2011; 108:16381-16385
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 16381-16385
-
-
Kumashiro, N.1
Erion, D.M.2
Zhang, D.3
-
7
-
-
85020297753
-
Hepatic diacylglycerol-associated protein kinase Ce translocation links hepatic steatosis to hepatic insulinresistanceinhumans
-
Ter Horst KW, Gilijamse PW, Versteeg RI, et al. Hepatic diacylglycerol-associated protein kinase Ce translocation links hepatic steatosis to hepatic insulinresistanceinhumans. CellReports 2017;19: 1997-2004
-
(2017)
CellReports
, vol.19
, pp. 1997-2004
-
-
Ter Horst, K.W.1
Gilijamse, P.W.2
Versteeg, R.I.3
-
8
-
-
63249121641
-
Hepatic stearoyl-CoA desaturase (SCD)-1 activity and diacylglycerol but not ceramide concentrations are increased in the nonalcoholic human fatty liver
-
Kotronen A, Seppänen-Laakso T, Westerbacka J, et al. Hepatic stearoyl-CoA desaturase (SCD)-1 activity and diacylglycerol but not ceramide concentrations are increased in the nonalcoholic human fatty liver. Diabetes 2009;58:203-208
-
(2009)
Diabetes
, vol.58
, pp. 203-208
-
-
Kotronen, A.1
Seppänen-Laakso, T.2
Westerbacka, J.3
-
9
-
-
84959104290
-
Hepatic ceramides dissociate steatosis and insulin resistance in patientswith non-alcoholic fatty liver disease
-
Luukkonen PK, Zhou Y, Sädevirta S, et al. Hepatic ceramides dissociate steatosis and insulin resistance in patientswith non-alcoholic fatty liver disease. J Hepatol 2016;64:1167-1175
-
(2016)
J Hepatol
, vol.64
, pp. 1167-1175
-
-
Luukkonen, P.K.1
Zhou, Y.2
Sädevirta, S.3
-
10
-
-
84856415487
-
The role of mitochondria in insulin resistance and type 2 diabetes mellitus
-
Szendroedi J, Phielix E, Roden M. The role of mitochondria in insulin resistance and type 2 diabetes mellitus. NatRev Endocrinol 2011;8:92-103
-
(2011)
NatRev Endocrinol
, vol.8
, pp. 92-103
-
-
Szendroedi, J.1
Phielix, E.2
Roden, M.3
-
11
-
-
84937738375
-
Adaptation of hepaticmitochondrial function in humans with non-alcoholic fatty liver is lost in steatohepatitis
-
KoliakiC, Szendroedi J, KaulK, et al. Adaptation of hepaticmitochondrial function in humans with non-alcoholic fatty liver is lost in steatohepatitis. Cell Metab 2015;21:739-746
-
(2015)
Cell Metab
, vol.21
, pp. 739-746
-
-
Koliaki, C.1
Szendroedi, J.2
Kaul, K.3
-
12
-
-
82955239838
-
Excessive hepatic mitochondrial TCA cycle and gluconeogenesis in humans with nonalcoholic fatty liver disease
-
Sunny NE, Parks EJ, Browning JD, Burgess SC. Excessive hepatic mitochondrial TCA cycle and gluconeogenesis in humans with nonalcoholic fatty liver disease. Cell Metab 2011;14:804-810
-
(2011)
Cell Metab
, vol.14
, pp. 804-810
-
-
Sunny, N.E.1
Parks, E.J.2
Browning, J.D.3
Burgess, S.C.4
-
13
-
-
79956336707
-
Transcriptional profile of genes involved in oxidative stress and antioxidantdefenseina dietarymurinemodel of steatohepatitis
-
Gornicka A, Morris-Stiff G, Thapaliya S, Papouchado BG, Berk M, Feldstein AE. Transcriptional profile of genes involved in oxidative stress and antioxidantdefenseina dietarymurinemodel of steatohepatitis. Antioxid Redox Signal 2011;15: 437-445
-
(2011)
Antioxid Redox Signal
, vol.15
, pp. 437-445
-
-
Gornicka, A.1
Morris-Stiff, G.2
Thapaliya, S.3
Papouchado, B.G.4
Berk, M.5
Feldstein, A.E.6
-
14
-
-
0035991444
-
In situ detection of lipid peroxidation and oxidative DNA damage in nonalcoholic fatty liver diseases
-
Seki S, Kitada T, Yamada T, Sakaguchi H, Nakatani K, Wakasa K. In situ detection of lipid peroxidation and oxidative DNA damage in nonalcoholic fatty liver diseases. J Hepatol 2002;37: 56-62
-
(2002)
J Hepatol
, vol.37
, pp. 56-62
-
-
Seki, S.1
Kitada, T.2
Yamada, T.3
Sakaguchi, H.4
Nakatani, K.5
Wakasa, K.6
-
15
-
-
84963957342
-
Lactosylceramide contributes to mitochondrial dysfunction in diabetes
-
Novgorodov SA, Riley CL, Yu J, et al. Lactosylceramide contributes to mitochondrial dysfunction in diabetes. J Lipid Res 2016;57:546-562
-
(2016)
J Lipid Res
, vol.57
, pp. 546-562
-
-
Novgorodov, S.A.1
Riley, C.L.2
Yu, J.3
-
16
-
-
70949101414
-
Link between plasma ceramides, inflammation and insulin resistance: Association with serum IL-6 concentration in patients with coronary heart disease
-
deMelloVD, LankinenM, SchwabU, et al. Link between plasma ceramides, inflammation and insulin resistance: Association with serum IL-6 concentration in patients with coronary heart disease. Diabetologia 2009;52:2612-2615
-
(2009)
Diabetologia
, vol.52
, pp. 2612-2615
-
-
DeMello, V.D.1
Lankinen, M.2
Schwab, U.3
-
17
-
-
85014078334
-
Plasma dihydroceramides are diabetes susceptibility biomarker candidates inmice and humans
-
Wigger L, Cruciani-Guglielmacci C, Nicolas A, et al. Plasma dihydroceramides are diabetes susceptibility biomarker candidates inmice and humans. Cell Reports 2017;18:2269-2279
-
(2017)
Cell Reports
, vol.18
, pp. 2269-2279
-
-
Wigger, L.1
Cruciani-Guglielmacci, C.2
Nicolas, A.3
-
18
-
-
78649433367
-
Histopathology of nonalcoholic fatty liver disease
-
Brunt EM, Tiniakos DG. Histopathology of nonalcoholic fatty liver disease. World J Gastroenterol 2010;16:5286-5296
-
(2010)
World J Gastroenterol
, vol.16
, pp. 5286-5296
-
-
Brunt, E.M.1
Tiniakos, D.G.2
-
19
-
-
20044374023
-
Design and validation of a histological scoring systemfor nonalcoholic fatty liver disease
-
Nonalcoholic Steatohepatitis Clinical Research Network
-
Kleiner DE, Brunt EM, Van Natta M, et al.; Nonalcoholic Steatohepatitis Clinical Research Network. Design and validation of a histological scoring systemfor nonalcoholic fatty liver disease. Hepatology 2005;41:1313-1321
-
(2005)
Hepatology
, vol.41
, pp. 1313-1321
-
-
De, K.1
Brunt, E.M.2
Van Natta, M.3
-
20
-
-
84977079490
-
Metabolic flexibility and oxidative capacity independently associate with insulin sensitivity in individuals with newly diagnosed type 2 diabetes
-
GDS group
-
Apostolopoulou M, Strassburger K, Herder C, et al.; GDS group. Metabolic flexibility and oxidative capacity independently associate with insulin sensitivity in individuals with newly diagnosed type 2 diabetes. Diabetologia 2016;59: 2203-2207
-
(2016)
Diabetologia
, vol.59
, pp. 2203-2207
-
-
Apostolopoulou, M.1
Strassburger, K.2
Herder, C.3
-
21
-
-
70350043496
-
Abnormal hepatic energy homeostasis in type 2 diabetes
-
Szendroedi J, Chmelik M, Schmid AI, et al. Abnormal hepatic energy homeostasis in type 2 diabetes. Hepatology 2009;50:1079-1086
-
(2009)
Hepatology
, vol.50
, pp. 1079-1086
-
-
Szendroedi, J.1
Chmelik, M.2
Schmid, A.I.3
-
22
-
-
79958134215
-
Mitochondrial ROS production under cellular stress: Comparison of different detectionmethods
-
Kuznetsov AV, Kehrer I, Kozlov AV, et al. Mitochondrial ROS production under cellular stress: Comparison of different detectionmethods. Anal Bioanal Chem 2011;400:2383-2390
-
(2011)
Anal Bioanal Chem
, vol.400
, pp. 2383-2390
-
-
Kuznetsov, A.V.1
Kehrer, I.2
Kozlov, A.V.3
-
23
-
-
84908613782
-
Tissuespecific differences in the development of insulin resistance in a mouse model for type 1 diabetes
-
Jelenik T, Séquaris G, Kaul K, et al. Tissuespecific differences in the development of insulin resistance in a mouse model for type 1 diabetes. Diabetes 2014;63:3856-3867
-
(2014)
Diabetes
, vol.63
, pp. 3856-3867
-
-
Jelenik, T.1
Séquaris, G.2
Kaul, K.3
-
24
-
-
84891872183
-
Association of subclinical inflammation with polyneuropathy in the older population: KORA F4 study
-
Herder C, BongaertsBWC, RathmannW, et al. Association of subclinical inflammation with polyneuropathy in the older population: KORA F4 study. Diabetes Care 2013;36:3663-3670
-
(2013)
Diabetes Care
, vol.36
, pp. 3663-3670
-
-
Herder, C.1
Bongaerts, B.W.C.2
Rathmann, W.3
-
25
-
-
84963770637
-
Cohort profile: The German Diabetes Study (GDS)
-
GDS Group
-
Szendroedi J, Saxena A, Weber KS, et al.; GDS Group. Cohort profile: The German Diabetes Study (GDS). Cardiovasc Diabetol 2016;15:59
-
(2016)
Cardiovasc Diabetol
, vol.15
, pp. 59
-
-
Szendroedi, J.1
Saxena, A.2
Weber, K.S.3
-
26
-
-
84877272187
-
An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action inmice
-
HollandWL, Adams AC, Brozinick JT, et al. An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action inmice. CellMetab 2013;17:790-797
-
(2013)
CellMetab
, vol.17
, pp. 790-797
-
-
Holland, W.L.1
Adams, A.C.2
Brozinick, J.T.3
-
27
-
-
78651260799
-
Receptor-mediated activation of ceramidase activity initiates thepleiotropic actionsof adiponectin
-
Holland WL, Miller RA, Wang ZV, et al. Receptor-mediated activation of ceramidase activity initiates thepleiotropic actionsof adiponectin. Nat Med 2011;17:55-63
-
(2011)
Nat Med
, vol.17
, pp. 55-63
-
-
Holland, W.L.1
Miller, R.A.2
Wang, Z.V.3
-
28
-
-
84943262988
-
Liver perilipin 5 expression worsens hepatosteatosis but not insulinresistanceinhighfat-fedmice
-
Trevino MB, Mazur-Hart D, Machida Y, et al. Liver perilipin 5 expression worsens hepatosteatosis but not insulinresistanceinhighfat-fedmice. Mol Endocrinol 2015;29:1414-1425
-
(2015)
Mol Endocrinol
, vol.29
, pp. 1414-1425
-
-
Trevino, M.B.1
Mazur-Hart, D.2
Machida, Y.3
-
29
-
-
77956022194
-
Inhibition of denovoceramidesynthesis reverses diet-induced insulin resistance and enhanceswhole-body oxygen consumption
-
UssherJR, Koves TR, CadeteVJ, et al. Inhibition of denovoceramidesynthesis reverses diet-induced insulin resistance and enhanceswhole-body oxygen consumption. Diabetes 2010;59:2453-2464
-
(2010)
Diabetes
, vol.59
, pp. 2453-2464
-
-
Ussher, J.R.1
Koves, T.R.2
Cadete, V.J.3
-
30
-
-
84890467958
-
The adipokine/ ceramide axis: Key aspects of insulin sensitization
-
Xia JY, Morley TS, Scherer PE. The adipokine/ ceramide axis: Key aspects of insulin sensitization. Biochimie 2014;96:130-139
-
(2014)
Biochimie
, vol.96
, pp. 130-139
-
-
Xia, J.Y.1
Morley, T.S.2
Scherer, P.E.3
-
31
-
-
84943658679
-
Effect of pioglitazone on plasma ceramides inadultswith metabolic syndrome
-
Warshauer JT, Lopez X, Gordillo R, et al. Effect of pioglitazone on plasma ceramides inadultswith metabolic syndrome. Diabetes Metab Res Rev 2015;31:734-744
-
(2015)
Diabetes Metab Res Rev
, vol.31
, pp. 734-744
-
-
Warshauer, J.T.1
Lopez, X.2
Gordillo, R.3
-
32
-
-
84969704993
-
Lipotoxicity in steatohepatitis occurs despite an increase in tricarboxylic acid cycle activity
-
Patterson RE, Kalavalapalli S, Williams CM, et al. Lipotoxicity in steatohepatitis occurs despite an increase in tricarboxylic acid cycle activity. AmJ Physiol EndocrinolMetab 2016;310: E484-E494
-
(2016)
AmJ Physiol EndocrinolMetab
, vol.310
, pp. E484-E494
-
-
Patterson, R.E.1
Kalavalapalli, S.2
Williams, C.M.3
-
33
-
-
0343883506
-
Direct interaction of GD3 ganglioside with mitochondria generates reactiveoxygen species followed by mitochondrial permeability transition, cytochromecrelease, andcaspaseactivation
-
García-Ruiz C, Colell A, París R, Fernández-Checa JC. Direct interaction of GD3 ganglioside with mitochondria generates reactiveoxygen species followed by mitochondrial permeability transition, cytochromecrelease, andcaspaseactivation. FASEBJ 2000;14:847-858
-
(2000)
FASEBJ
, vol.14
, pp. 847-858
-
-
García-Ruiz, C.1
Colell, A.2
París, R.3
Fernández-Checa, J.C.4
-
35
-
-
85017175236
-
Structural biology: Receptors grease the metabolic wheels
-
Holland WL, Scherer PE. Structural biology: Receptors grease the metabolic wheels. Nature 2017;544:42-44
-
(2017)
Nature
, vol.544
, pp. 42-44
-
-
Holland, W.L.1
Scherer, P.E.2
-
36
-
-
84901936622
-
Sphingolipid metabolites in inflammatory disease
-
Maceyka M, Spiegel S. Sphingolipid metabolites in inflammatory disease. Nature 2014;510: 58-67
-
(2014)
Nature
, vol.510
, pp. 58-67
-
-
Maceyka, M.1
Spiegel, S.2
-
37
-
-
63249117466
-
Plasma ceramides are elevated in obese subjects with type 2 diabetes and correlate with the severity of insulin resistance
-
Haus JM, Kashyap SR, Kasumov T, et al. Plasma ceramides are elevated in obese subjects with type 2 diabetes and correlate with the severity of insulin resistance. Diabetes 2009;58: 337-343
-
(2009)
Diabetes
, vol.58
, pp. 337-343
-
-
Haus, J.M.1
Kashyap, S.R.2
Kasumov, T.3
-
38
-
-
77952970776
-
Effects of sphingolipid synthesis inhibition on cholesterol gallstone formation in C57BL/6J mice
-
Lee BJ, Kim JS, Kim BK, et al. Effects of sphingolipid synthesis inhibition on cholesterol gallstone formation in C57BL/6J mice. J Gastroenterol Hepatol 2010;25:1105-1110
-
(2010)
J Gastroenterol Hepatol
, vol.25
, pp. 1105-1110
-
-
Lee, B.J.1
Kim, J.S.2
Kim, B.K.3
|