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Volumn 6, Issue 1, 2010, Pages

Recombinant protein vaccines against the asexual blood-stages of Plasmodium falciparum

Author keywords

Blood stages; Malaria; Plasmodium; Recombinant protein; Vaccine

Indexed keywords

AGATOLIMOD; ALUMINUM HYDROXIDE; APICAL MEMBRANE ANTIGEN 1; AS 02; AS 02 A; AS 02A; CIRCUMSPOROZOITE PROTEIN; ERYTHROCYTE BINDING ANTIGEN; GLUTAMATE RICH PROTEIN; GMZ 2; IMMUNOLOGICAL ADJUVANT; MALARIA VACCINE; MEROZOITE SURFACE ANTIGEN 3; MEROZOITE SURFACE PROTEIN 1; MEROZOITE SURFACE PROTEIN 2; MONTANIDE; MONTANIDE ISA 720; PARASITE ANTIGEN; PEPTIDE VACCINE; PF 07 0128; PF 10 0344; PF 10 0345; PF 11 0344; PFB 0300 C; PFB 0340 C; PFI 1475 W; RECOMBINANT PROTEIN; RECOMBINANT VACCINE; RING INFECTED ERYTHROCYTE SURFACE ANTIGEN; SERINE REPEAT ANTIGEN 5; UNCLASSIFIED DRUG; WATER OIL CREAM; APICAL MEMBRANE ANTIGEN I, PLASMODIUM; MEMBRANE PROTEIN; MEROZOITE SURFACE PROTEIN 2, PLASMODIUM; PROTOZOAL PROTEIN; PROTOZOON ANTIBODY;

EID: 85046915432     PISSN: 15548600     EISSN: 15548619     Source Type: Journal    
DOI: 10.4161/hv.6.1.10712     Document Type: Review
Times cited : (54)

References (165)
  • 1
    • 0017311840 scopus 로고
    • Human malaria parasites in continuous culture
    • Trager W, Jensen JB. Human malaria parasites in continuous culture. Science 1976; 193:673-5.
    • (1976) Science , vol.193 , pp. 673-675
    • Trager, W.1    Jensen, J.B.2
  • 3
    • 0020771266 scopus 로고
    • Expression of Plasmodium falciparum blood-stage antigens in Escherichia coli: Detection with antibodies from immune humans
    • Kemp DJ, Coppel RL, Cowman AF, Saint RB, Brown GV, Anders RF. Expression of Plasmodium falciparum blood-stage antigens in Escherichia coli: detection with antibodies from immune humans. Proc Natl Acad Sci USA 1983; 80:3787-91.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 3787-3791
    • Kemp, D.J.1    Coppel, R.L.2    Cowman, A.F.3    Saint, R.B.4    Brown, G.V.5    Anders, R.F.6
  • 4
    • 34347386674 scopus 로고    scopus 로고
    • Profiling the antibody immune response against blood stage malaria vaccine candidates
    • Gray JC, Corran PH, Mangia E, Gaunt MW, Li Q, Tetteh KK, et al. Profiling the antibody immune response against blood stage malaria vaccine candidates. Clin Chem 2007; 53:1244-53.
    • (2007) Clin Chem , vol.53 , pp. 1244-1253
    • Gray, J.C.1    Corran, P.H.2    Mangia, E.3    Gaunt, M.W.4    Li, Q.5    Tetteh, K.K.6
  • 5
    • 42949093708 scopus 로고    scopus 로고
    • Breadth and magnitude of antibody responses to multiple Plasmodium falciparum merozoite antigens are associated with protection from clinical malaria
    • Osier FH, Fegan G, Polley SD, Murungi L, Verra F, Tetteh KK, et al. Breadth and magnitude of antibody responses to multiple Plasmodium falciparum merozoite antigens are associated with protection from clinical malaria. Infect Immun 2008; 76:2240-8.
    • (2008) Infect Immun , vol.76 , pp. 2240-2248
    • Osier, F.H.1    Fegan, G.2    Polley, S.D.3    Murungi, L.4    Verra, F.5    Tetteh, K.K.6
  • 6
    • 0020383019 scopus 로고
    • Biosynthesis and processing of a Plasmodium falciparum schizont antigen recognized by immune serum and a monoclonal antibody
    • Holder AA, Freeman RR. Biosynthesis and processing of a Plasmodium falciparum schizont antigen recognized by immune serum and a monoclonal antibody. J Exp Med 1982; 156:1528-38.
    • (1982) J Exp Med , vol.156 , pp. 1528-1538
    • Holder, A.A.1    Freeman, R.R.2
  • 8
    • 0021895236 scopus 로고
    • Recognition of a Mr 56 K glycoprotein on the surface of Plasmodium falciparum merozoites by mouse monoclonal antibodies
    • Stanley HA, Howard RF, Reese RT. Recognition of a Mr 56 K glycoprotein on the surface of Plasmodium falciparum merozoites by mouse monoclonal antibodies. J Immunol 1985; 134:3439-44.
    • (1985) J Immunol , vol.134 , pp. 3439-3444
    • Stanley, H.A.1    Howard, R.F.2    Reese, R.T.3
  • 10
    • 0022639206 scopus 로고
    • Affinity purification of human antibodies directed against cloned antigens of Plasmodium falciparum
    • Crewther PE, Bianco AE, Brown GV, Coppel RL, Stahl HD, Kemp DJ, et al. Affinity purification of human antibodies directed against cloned antigens of Plasmodium falciparum. J Immunol Methods 1986; 86:257-64.
    • (1986) J Immunol Methods , vol.86 , pp. 257-264
    • Crewther, P.E.1    Bianco, A.E.2    Brown, G.V.3    Coppel, R.L.4    Stahl, H.D.5    Kemp, D.J.6
  • 11
    • 0026780769 scopus 로고
    • Protection of Aotus monkeys from malaria infection by immunization with recombinant hybrid proteins
    • Knapp B, Hundt E, Enders B, Kupper HA. Protection of Aotus monkeys from malaria infection by immunization with recombinant hybrid proteins. Infect Immun 1992; 60:2397-401.
    • (1992) Infect Immun , vol.60 , pp. 2397-2401
    • Knapp, B.1    Hundt, E.2    Enders, B.3    Kupper, H.A.4
  • 12
    • 0022490164 scopus 로고
    • Immunization of Aotus monkeys with recombinant proteins of an erythrocyte surface antigen of Plasmodium falciparum
    • Collins WE, Anders RF, Pappaioanou M, Campbell GH, Brown GV, Kemp DJ, et al. Immunization of Aotus monkeys with recombinant proteins of an erythrocyte surface antigen of Plasmodium falciparum. Nature 1986; 323:259-62.
    • (1986) Nature , vol.323 , pp. 259-262
    • Collins, W.E.1    Anders, R.F.2    Pappaioanou, M.3    Campbell, G.H.4    Brown, G.V.5    Kemp, D.J.6
  • 13
    • 0019775688 scopus 로고
    • Immunization against blood-stage rodent malaria using purified parasite antigens
    • Holder AA, Freeman RR. Immunization against blood-stage rodent malaria using purified parasite antigens. Nature 1981; 294:361-4.
    • (1981) Nature , vol.294 , pp. 361-364
    • Holder, A.A.1    Freeman, R.R.2
  • 14
    • 0021287744 scopus 로고
    • Biosynthesis of a putative protective Plasmodium knowlesi merozoite antigen
    • Deans JA, Thomas AW, Alderson T, Cohen S. Biosynthesis of a putative protective Plasmodium knowlesi merozoite antigen. Mol Biochem Parasitol 1984; 11:189-204.
    • (1984) Mol Biochem Parasitol , vol.11 , pp. 189-204
    • Deans, J.A.1    Thomas, A.W.2    Alderson, T.3    Cohen, S.4
  • 16
    • 0022373071 scopus 로고
    • A Plasmodium falciparum antigen that binds to host erythrocytes and merozoites
    • Camus D, Hadley TJ. A Plasmodium falciparum antigen that binds to host erythrocytes and merozoites. Science 1985; 230:553-6.
    • (1985) Science , vol.230 , pp. 553-556
    • Camus, D.1    Hadley, T.J.2
  • 17
    • 0025169361 scopus 로고
    • Primary structure of the 175 K Plasmodium falciparum erythrocyte binding antigen and identification of a peptide which elicits antibodies that inhibit malaria merozoite invasion
    • Sim BK, Orlandi PA, Haynes JD, Klotz FW, Carter JM, Camus D, et al. Primary structure of the 175 K Plasmodium falciparum erythrocyte binding antigen and identification of a peptide which elicits antibodies that inhibit malaria merozoite invasion. J Cell Biol 1990; 111:1877-84.
    • (1990) J Cell Biol , vol.111 , pp. 1877-1884
    • Sim, B.K.1    Orlandi, P.A.2    Haynes, J.D.3    Klotz, F.W.4    Carter, J.M.5    Camus, D.6
  • 18
    • 0025938181 scopus 로고
    • Primary structure and localization of a conserved immunogenic Plasmodium falciparum glutamate rich protein (GLURP) expressed in both the preerythrocytic and erythrocytic stages of the vertebrate life cycle
    • Borre MB, Dziegiel M, Hogh B, Petersen E, Rieneck K, Riley E, et al. Primary structure and localization of a conserved immunogenic Plasmodium falciparum glutamate rich protein (GLURP) expressed in both the preerythrocytic and erythrocytic stages of the vertebrate life cycle. Mol Biochem Parasitol 1991; 49:119-31.
    • (1991) Mol Biochem Parasitol , vol.49 , pp. 119-131
    • Borre, M.B.1    Dziegiel, M.2    Hogh, B.3    Petersen, E.4    Rieneck, K.5    Riley, E.6
  • 19
    • 0027989813 scopus 로고
    • Merozoite surface protein-3: A malaria protein inducing antibodies that promote Plasmodium falciparum killing by cooperation with blood monocytes
    • Oeuvray C, Bouharoun-Tayoun H, Gras-Masse H, Bottius E, Kaidoh T, Aikawa M, et al. Merozoite surface protein-3: a malaria protein inducing antibodies that promote Plasmodium falciparum killing by cooperation with blood monocytes. Blood 1994; 84:1594-602.
    • (1994) Blood , vol.84 , pp. 1594-1602
    • Oeuvray, C.1    Bouharoun-Tayoun, H.2    Gras-Masse, H.3    Bottius, E.4    Kaidoh, T.5    Aikawa, M.6
  • 20
    • 0028099611 scopus 로고
    • Molecular variation in a novel polymorphic antigen associated with Plasmodium falciparum merozoites
    • McColl DJ, Silva A, Foley M, Kun JF, Favaloro JM, Thompson JK, et al. Molecular variation in a novel polymorphic antigen associated with Plasmodium falciparum merozoites. Mol Biochem Parasitol 1994; 68:53-67.
    • (1994) Mol Biochem Parasitol , vol.68 , pp. 53-67
    • McColl, D.J.1    Silva, A.2    Foley, M.3    Kun, J.F.4    Favaloro, J.M.5    Thompson, J.K.6
  • 21
    • 0024555014 scopus 로고
    • Structure and expression of the Plasmodium falciparum SERA gene
    • Li WB, Bzik DJ, Horii T, Inselburg J. Structure and expression of the Plasmodium falciparum SERA gene. Mol Biochem Parasitol 1989; 33:13-25.
    • (1989) Mol Biochem Parasitol , vol.33 , pp. 13-25
    • Li, W.B.1    Bzik, D.J.2    Horii, T.3    Inselburg, J.4
  • 22
    • 68949172361 scopus 로고    scopus 로고
    • Structural insights into the protease-like antigen Plasmodium falciparum SERA5 and its noncanonical active-site serine
    • Hodder AN, Malby RL, Clarke OB, Fairlie WD, Colman PM, Crabb BS, et al. Structural insights into the protease-like antigen Plasmodium falciparum SERA5 and its noncanonical active-site serine. J Mol Biol 2009; 392:154-65.
    • (2009) J Mol Biol , vol.392 , pp. 154-165
    • Hodder, A.N.1    Malby, R.L.2    Clarke, O.B.3    Fairlie, W.D.4    Colman, P.M.5    Crabb, B.S.6
  • 23
    • 34548425095 scopus 로고    scopus 로고
    • Asexual blood-stage malaria vaccine development: Facing the challenges
    • Genton B, Reed ZH. Asexual blood-stage malaria vaccine development: facing the challenges. Curr Opin Infect Dis 2007; 20:467-75.
    • (2007) Curr Opin Infect Dis , vol.20 , pp. 467-475
    • Genton, B.1    Reed, Z.H.2
  • 24
    • 0037015614 scopus 로고    scopus 로고
    • Genome sequence of the human malaria parasite Plasmodium falciparum
    • Gardner MJ, Hall N, Fung E, White O, Berriman M, Hyman RW, et al. Genome sequence of the human malaria parasite Plasmodium falciparum. Nature 2002; 419:498-511.
    • (2002) Nature , vol.419 , pp. 498-511
    • Gardner, M.J.1    Hall, N.2    Fung, E.3    White, O.4    Berriman, M.5    Hyman, R.W.6
  • 25
    • 28844434092 scopus 로고    scopus 로고
    • Distinct protein classes including novel merozoite surface antigens in Raftlike membranes of Plasmodium falciparum
    • Sanders PR, Gilson PR, Cantin GT, Greenbaum DC, Nebl T, Carucci DJ, et al. Distinct protein classes including novel merozoite surface antigens in Raftlike membranes of Plasmodium falciparum. J Biol Chem 2005; 280:40169-76.
    • (2005) J Biol Chem , vol.280 , pp. 40169-40176
    • Sanders, P.R.1    Gilson, P.R.2    Cantin, G.T.3    Greenbaum, D.C.4    Nebl, T.5    Carucci, D.J.6
  • 26
    • 38649119184 scopus 로고    scopus 로고
    • Transcriptionally active PCR for antigen identification and vaccine development: In vitro genome-wide screening and in vivo immunogenicity
    • Regis DP, Dobano C, Quinones-Olson P, Liang X, Graber NL, Stefaniak ME, et al. Transcriptionally active PCR for antigen identification and vaccine development: in vitro genome-wide screening and in vivo immunogenicity. Mol Biochem Parasitol 2008; 158:32-45.
    • (2008) Mol Biochem Parasitol , vol.158 , pp. 32-45
    • Regis, D.P.1    Dobano, C.2    Quinones-Olson, P.3    Liang, X.4    Graber, N.L.5    Stefaniak, M.E.6
  • 27
    • 39849106625 scopus 로고    scopus 로고
    • Rapid identification of malaria vaccine candidates based on alpha-helical coiled coil protein motif
    • Villard V, Agak GW, Frank G, Jafarshad A, Servis C, Nebie I, et al. Rapid identification of malaria vaccine candidates based on alpha-helical coiled coil protein motif. PLoS One 2007; 2:645.
    • (2007) PLoS One , vol.2 , pp. 645
    • Villard, V.1    Agak, G.W.2    Frank, G.3    Jafarshad, A.4    Servis, C.5    Nebie, I.6
  • 28
    • 66249119722 scopus 로고    scopus 로고
    • Sequence conservation in Plasmodium falciparum alpha-helical coiled coil domains proposed for vaccine development
    • Kulangara C, Kajava AV, Corradin G, Felger I. Sequence conservation in Plasmodium falciparum alpha-helical coiled coil domains proposed for vaccine development. PLoS One 2009; 4:5419.
    • (2009) PLoS One , vol.4 , pp. 5419
    • Kulangara, C.1    Kajava, A.V.2    Corradin, G.3    Felger, I.4
  • 29
    • 33845914565 scopus 로고    scopus 로고
    • Genome-wide variation and identification of vaccine targets in the Plasmodium falciparum genome
    • Mu J, Awadalla P, Duan J, McGee KM, Keebler J, Seydel K, et al. Genome-wide variation and identification of vaccine targets in the Plasmodium falciparum genome. Nat Genet 2007; 39:126-30.
    • (2007) Nat Genet , vol.39 , pp. 126-130
    • Mu, J.1    Awadalla, P.2    Duan, J.3    McGee, K.M.4    Keebler, J.5    Seydel, K.6
  • 31
    • 70350575194 scopus 로고    scopus 로고
    • The carboxy-terminus of merozoite surface protein 1: Structure, specific antibodies and immunity to malaria
    • Holder AA. The carboxy-terminus of merozoite surface protein 1: structure, specific antibodies and immunity to malaria. Parasitology 2009; 136:1445-56.
    • (2009) Parasitology , vol.136 , pp. 1445-1456
    • Holder, A.A.1
  • 32
    • 0037086437 scopus 로고    scopus 로고
    • A recombinant blood-stage malaria vaccine reduces Plasmodium falciparum density and exerts selective pressure on parasite populations in a phase 1-2b trial in Papua New Guinea
    • Genton B, Betuela I, Felger I, Al-Yaman F, Anders RF, Saul A, et al. A recombinant blood-stage malaria vaccine reduces Plasmodium falciparum density and exerts selective pressure on parasite populations in a phase 1-2b trial in Papua New Guinea. J Infect Dis 2002; 185:820-7.
    • (2002) J Infect Dis , vol.185 , pp. 820-827
    • Genton, B.1    Betuela, I.2    Felger, I.3    Al-Yaman, F.4    Anders, R.F.5    Saul, A.6
  • 33
    • 0025310377 scopus 로고
    • A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasioninhibiting antibodies
    • Blackman MJ, Heidrich HG, Donachie S, McBride JS, Holder AA. A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasioninhibiting antibodies. J Exp Med 1990; 172:379-82.
    • (1990) J Exp Med , vol.172 , pp. 379-382
    • Blackman, M.J.1    Heidrich, H.G.2    Donachie, S.3    McBride, J.S.4    Holder, A.A.5
  • 34
    • 0026514240 scopus 로고
    • Secondary processing of the Plasmodium falciparum merozoite surface protein-1 (MSP1) by a calcium-dependent membranebound serine protease: Shedding of MSP133 as a noncovalently associated complex with other fragments of the MSP1
    • Blackman MJ, Holder AA. Secondary processing of the Plasmodium falciparum merozoite surface protein-1 (MSP1) by a calcium-dependent membranebound serine protease: shedding of MSP133 as a noncovalently associated complex with other fragments of the MSP1. Mol Biochem Parasitol 1992; 50:307-15.
    • (1992) Mol Biochem Parasitol , vol.50 , pp. 307-315
    • Blackman, M.J.1    Holder, A.A.2
  • 35
    • 0032866084 scopus 로고    scopus 로고
    • Phase I trial of two recombinant vaccines containing the 19 kd carboxy terminal fragment of Plasmodium falciparum merozoite surface protein 1 (msp-1(19)) and T helper epitopes of tetanus toxoid
    • Keitel WA, Kester KE, Atmar RL, White AC, Bond NH, Holland CA, et al. Phase I trial of two recombinant vaccines containing the 19 kd carboxy terminal fragment of Plasmodium falciparum merozoite surface protein 1 (msp-1(19)) and T helper epitopes of tetanus toxoid. Vaccine 1999; 18:531-9.
    • (1999) Vaccine , vol.18 , pp. 531-539
    • Keitel, W.A.1    Kester, K.E.2    Atmar, R.L.3    White, A.C.4    Bond, N.H.5    Holland, C.A.6
  • 36
    • 33644904970 scopus 로고    scopus 로고
    • Phase I safety and immunogenicity trial of FMP1/AS02A, a Plasmodium falciparum MSP-1 asexual blood stage vaccine
    • Ockenhouse CF, Angov E, Kester KE, Diggs C, Soisson L, Cummings JF, et al. Phase I safety and immunogenicity trial of FMP1/AS02A, a Plasmodium falciparum MSP-1 asexual blood stage vaccine. Vaccine 2006; 24:3009-17.
    • (2006) Vaccine , vol.24 , pp. 3009-3017
    • Ockenhouse, C.F.1    Angov, E.2    Kester, K.E.3    Diggs, C.4    Soisson, L.5    Cummings, J.F.6
  • 37
    • 33751406418 scopus 로고    scopus 로고
    • Phase 1 randomized double-blind safety and immunogenicity trial of Plasmodium falciparum malaria merozoite surface protein FMP1 vaccine, adjuvanted with AS02A, in adults in western Kenya
    • Stoute JA, Gombe J, Withers MR, Siangla J, McKinney D, Onyango M, et al. Phase 1 randomized double-blind safety and immunogenicity trial of Plasmodium falciparum malaria merozoite surface protein FMP1 vaccine, adjuvanted with AS02A, in adults in western Kenya. Vaccine 2007; 25:176-84.
    • (2007) Vaccine , vol.25 , pp. 176-184
    • Stoute, J.A.1    Gombe, J.2    Withers, M.R.3    Siangla, J.4    McKinney, D.5    Onyango, M.6
  • 38
    • 74949092905 scopus 로고    scopus 로고
    • Thera MA, Doumbo OK, Coulibaly D, Diallo DA, Sagara I, Dicko A, et al. Safety and allele-specific immunogenicity of a malaria vaccine in Malian adults: results of a phase I randomized trial. PLoS Clin Trials 2006; 1:34.
    • Thera MA, Doumbo OK, Coulibaly D, Diallo DA, Sagara I, Dicko A, et al. Safety and allele-specific immunogenicity of a malaria vaccine in Malian adults: results of a phase I randomized trial. PLoS Clin Trials 2006; 1:34.
  • 39
    • 74949126385 scopus 로고    scopus 로고
    • Withers MR, McKinney D, Ogutu BR, Waitumbi JN, Milman JB, Apollo OJ, et al. Safety and reactogenicity of an MSP-1 malaria vaccine candidate: a randomized phase Ib dose-escalation trial in Kenyan children. PLoS Clin Trials 2006; 1:32.
    • Withers MR, McKinney D, Ogutu BR, Waitumbi JN, Milman JB, Apollo OJ, et al. Safety and reactogenicity of an MSP-1 malaria vaccine candidate: a randomized phase Ib dose-escalation trial in Kenyan children. PLoS Clin Trials 2006; 1:32.
  • 40
    • 61849177531 scopus 로고    scopus 로고
    • Blood stage malaria vaccine eliciting high antigen-specific antibody concentrations confers no protection to young children in western Kenya
    • Ogutu BR, Apollo OJ, McKinney D, Okoth W, Siangla J, Dubovsky F, et al. Blood stage malaria vaccine eliciting high antigen-specific antibody concentrations confers no protection to young children in western Kenya. PLoS One 2009; 4:4708.
    • (2009) PLoS One , vol.4 , pp. 4708
    • Ogutu, B.R.1    Apollo, O.J.2    McKinney, D.3    Okoth, W.4    Siangla, J.5    Dubovsky, F.6
  • 41
    • 34249790146 scopus 로고    scopus 로고
    • Malkin E, Long CA, Stowers AW, Zou L, Singh S, MacDonald NJ, et al. Phase 1 study of two merozoite surface protein 1 (MSP1(42)) vaccines for Plasmodium falciparum malaria. PLoS Clin Trials 2007; 2:12.
    • Malkin E, Long CA, Stowers AW, Zou L, Singh S, MacDonald NJ, et al. Phase 1 study of two merozoite surface protein 1 (MSP1(42)) vaccines for Plasmodium falciparum malaria. PLoS Clin Trials 2007; 2:12.
  • 42
    • 64849115291 scopus 로고    scopus 로고
    • The TLR9 ligand CpG promotes the acquisition of Plasmodium falciparumspecific memory B cells in malaria-naive individuals
    • Crompton PD, Mircetic M, Weiss G, Baughman A, Huang CY, Topham DJ, et al. The TLR9 ligand CpG promotes the acquisition of Plasmodium falciparumspecific memory B cells in malaria-naive individuals. J Immunol 2009; 182:3318-26.
    • (2009) J Immunol , vol.182 , pp. 3318-3326
    • Crompton, P.D.1    Mircetic, M.2    Weiss, G.3    Baughman, A.4    Huang, C.Y.5    Topham, D.J.6
  • 43
    • 74849140995 scopus 로고    scopus 로고
    • www.ClinicalTrials.gov. Phase I study of the safety and immunogenicity of BSAM-2/Alhydrogel (Registered Trademark) + CpG 7909, an asexual blood stage vaccine for Plasmodium falciparum malaria in adults in the US and Mali. 2009; NCT00889616.
    • www.ClinicalTrials.gov. Phase I study of the safety and immunogenicity of BSAM-2/Alhydrogel (Registered Trademark) + CpG 7909, an asexual blood stage vaccine for Plasmodium falciparum malaria in adults in the US and Mali. 2009; NCT00889616.
  • 44
    • 20144388222 scopus 로고    scopus 로고
    • A human phase 1 vaccine clinical trial of the Plasmodium falciparum malaria vaccine candidate apical membrane antigen 1 in Montanide ISA 720 adjuvant
    • Saul A, Lawrence G, Allworth A, Elliott S, Anderson K, Rzepczyk C, et al. A human phase 1 vaccine clinical trial of the Plasmodium falciparum malaria vaccine candidate apical membrane antigen 1 in Montanide ISA 720 adjuvant. Vaccine 2005; 23:3076-83.
    • (2005) Vaccine , vol.23 , pp. 3076-3083
    • Saul, A.1    Lawrence, G.2    Allworth, A.3    Elliott, S.4    Anderson, K.5    Rzepczyk, C.6
  • 45
    • 0036266921 scopus 로고    scopus 로고
    • Purification, characterization and immunogenicity of the refolded ectodomain of the Plasmodium falciparum apical membrane antigen 1 expressed in Escherichia coli
    • Dutta S, Lalitha PV, Ware LA, Barbosa A, Moch JK, Vassell MA, et al. Purification, characterization and immunogenicity of the refolded ectodomain of the Plasmodium falciparum apical membrane antigen 1 expressed in Escherichia coli. Infect Immun 2002; 70:3101-10.
    • (2002) Infect Immun , vol.70 , pp. 3101-3110
    • Dutta, S.1    Lalitha, P.V.2    Ware, L.A.3    Barbosa, A.4    Moch, J.K.5    Vassell, M.A.6
  • 46
    • 34247355050 scopus 로고    scopus 로고
    • Phase I dose escalation safety and immunogenicity trial of Plasmodium falciparum apical membrane protein (AMA-1) FMP2.1, adjuvanted with AS02A, in malaria-naive adults at the Walter Reed Army Institute of Research
    • Polhemus ME, Magill AJ, Cummings JF, Kester KE, Ockenhouse CF, Lanar DE, et al. Phase I dose escalation safety and immunogenicity trial of Plasmodium falciparum apical membrane protein (AMA-1) FMP2.1, adjuvanted with AS02A, in malaria-naive adults at the Walter Reed Army Institute of Research. Vaccine 2007; 25:4203-12.
    • (2007) Vaccine , vol.25 , pp. 4203-4212
    • Polhemus, M.E.1    Magill, A.J.2    Cummings, J.F.3    Kester, K.E.4    Ockenhouse, C.F.5    Lanar, D.E.6
  • 47
    • 44849126049 scopus 로고    scopus 로고
    • Safety and immunogenicity of an AMA-1 malaria vaccine in Malian adults: Results of a phase 1 randomized controlled trial
    • Thera MA, Doumbo OK, Coulibaly D, Diallo DA, Kone AK, Guindo AB, et al. Safety and immunogenicity of an AMA-1 malaria vaccine in Malian adults: results of a phase 1 randomized controlled trial. PLoS One 2008; 3:1465.
    • (2008) PLoS One , vol.3 , pp. 1465
    • Thera, M.A.1    Doumbo, O.K.2    Coulibaly, D.3    Diallo, D.A.4    Kone, A.K.5    Guindo, A.B.6
  • 48
    • 61549094354 scopus 로고    scopus 로고
    • Cell-mediated immunity elicited by the blood stage malaria vaccine apical membrane antigen 1 in Malian adults: Results of a Phase I randomized trial
    • Lyke KE, Daou M, Diarra I, Kone A, Kouriba B, Thera MA, et al. Cell-mediated immunity elicited by the blood stage malaria vaccine apical membrane antigen 1 in Malian adults: results of a Phase I randomized trial. Vaccine 2009; 27:2171-6.
    • (2009) Vaccine , vol.27 , pp. 2171-2176
    • Lyke, K.E.1    Daou, M.2    Diarra, I.3    Kone, A.4    Kouriba, B.5    Thera, M.A.6
  • 49
    • 65449181983 scopus 로고    scopus 로고
    • Phase 1/2a study of the malaria vaccine candidate apical membrane antigen-1 (AMA-1) administered in adjuvant system AS01B or AS02A
    • Spring MD, Cummings JF, Ockenhouse CF, Dutta S, Reidler R, Angov E, et al. Phase 1/2a study of the malaria vaccine candidate apical membrane antigen-1 (AMA-1) administered in adjuvant system AS01B or AS02A. PLoS One 2009; 4:5254.
    • (2009) PLoS One , vol.4 , pp. 5254
    • Spring, M.D.1    Cummings, J.F.2    Ockenhouse, C.F.3    Dutta, S.4    Reidler, R.5    Angov, E.6
  • 51
    • 21144469605 scopus 로고    scopus 로고
    • Phase 1 clinical trial of apical membrane antigen 1: An asexual blood-stage vaccine for Plasmodium falciparum malaria
    • Malkin EM, Diemert DJ, McArthur JH, Perreault JR, Miles AP, Giersing BK, et al. Phase 1 clinical trial of apical membrane antigen 1: an asexual blood-stage vaccine for Plasmodium falciparum malaria. Infect Immun 2005; 73:3677-85.
    • (2005) Infect Immun , vol.73 , pp. 3677-3685
    • Malkin, E.M.1    Diemert, D.J.2    McArthur, J.H.3    Perreault, J.R.4    Miles, A.P.5    Giersing, B.K.6
  • 52
    • 40449105608 scopus 로고    scopus 로고
    • Impact of a Plasmodium falciparum AMA1 vaccine on antibody responses in adult Malians
    • Dicko A, Diemert DJ, Sagara I, Sogoba M, Niambele MB, Assadou MH, et al. Impact of a Plasmodium falciparum AMA1 vaccine on antibody responses in adult Malians. PLoS One 2007; 2:1045.
    • (2007) PLoS One , vol.2 , pp. 1045
    • Dicko, A.1    Diemert, D.J.2    Sagara, I.3    Sogoba, M.4    Niambele, M.B.5    Assadou, M.H.6
  • 53
    • 45349103077 scopus 로고    scopus 로고
    • Phase 1 study of a combination AMA1 blood stage malaria vaccine in Malian children
    • Dicko A, Sagara I, Ellis RD, Miura K, Guindo O, Kamate B, et al. Phase 1 study of a combination AMA1 blood stage malaria vaccine in Malian children. PLoS One 2008; 3:1563.
    • (2008) PLoS One , vol.3 , pp. 1563
    • Dicko, A.1    Sagara, I.2    Ellis, R.D.3    Miura, K.4    Guindo, O.5    Kamate, B.6
  • 54
    • 67349273039 scopus 로고    scopus 로고
    • A randomized controlled phase 2 trial of the blood stage AMA1-C1/Alhydrogel malaria vaccine in children in Mali
    • Sagara I, Dicko A, Ellis RD, Fay MP, Diawara SI, Assadou MH, et al. A randomized controlled phase 2 trial of the blood stage AMA1-C1/Alhydrogel malaria vaccine in children in Mali. Vaccine 2009; 27:3090-8.
    • (2009) Vaccine , vol.27 , pp. 3090-3098
    • Sagara, I.1    Dicko, A.2    Ellis, R.D.3    Fay, M.P.4    Diawara, S.I.5    Assadou, M.H.6
  • 55
    • 51449101218 scopus 로고    scopus 로고
    • Phase 1 trial of AMA1-C1/Alhydrogel plus CPG 7909: An asexual blood-stage vaccine for Plasmodium falciparum malaria
    • Mullen GE, Ellis RD, Miura K, Malkin E, Nolan C, Hay M, et al. Phase 1 trial of AMA1-C1/Alhydrogel plus CPG 7909: an asexual blood-stage vaccine for Plasmodium falciparum malaria. PLoS One 2008; 3:2940.
    • (2008) PLoS One , vol.3 , pp. 2940
    • Mullen, G.E.1    Ellis, R.D.2    Miura, K.3    Malkin, E.4    Nolan, C.5    Hay, M.6
  • 56
    • 67349224673 scopus 로고    scopus 로고
    • A Phase 1 study of the blood-stage malaria vaccine candidate AMA1-C1/Alhydrogel with CPG 7909, using two different formulations and dosing intervals
    • Ellis RD, Mullen GE, Pierce M, Martin LB, Miura K, Fay MP, et al. A Phase 1 study of the blood-stage malaria vaccine candidate AMA1-C1/Alhydrogel with CPG 7909, using two different formulations and dosing intervals. Vaccine 2009; 27:4104-9.
    • (2009) Vaccine , vol.27 , pp. 4104-4109
    • Ellis, R.D.1    Mullen, G.E.2    Pierce, M.3    Martin, L.B.4    Miura, K.5    Fay, M.P.6
  • 57
    • 70849089713 scopus 로고    scopus 로고
    • Sagara I, Ellis RD, Dicko A, Niambele MB, Kamate B, Guindo O, et al. A randomized and controlled Phase 1 study of the safety and immunogenicity of the AMA1-C1/Alhydrogel((R)) + CPG 7909 vaccine for Plasmodium falciparum malaria in semi-immune Malian adults. Vaccine 2009.
    • Sagara I, Ellis RD, Dicko A, Niambele MB, Kamate B, Guindo O, et al. A randomized and controlled Phase 1 study of the safety and immunogenicity of the AMA1-C1/Alhydrogel((R)) + CPG 7909 vaccine for Plasmodium falciparum malaria in semi-immune Malian adults. Vaccine 2009.
  • 58
    • 74949132328 scopus 로고    scopus 로고
    • www.ClinicalTrials.gov. Malaria vaccine for children in Mali. 2009; NCT00740090.
    • www.ClinicalTrials.gov. Malaria vaccine for children in Mali. 2009; NCT00740090.
  • 59
    • 74949110648 scopus 로고    scopus 로고
    • www.ClinicalTrials.gov. A study to assess safety, immunogenicity and parasite growth inhibition of an asexual blood stage vaccine for P. falciparum malaria. 2009; NCT00984763.
    • www.ClinicalTrials.gov. A study to assess safety, immunogenicity and parasite growth inhibition of an asexual blood stage vaccine for P. falciparum malaria. 2009; NCT00984763.
  • 60
    • 74949096305 scopus 로고    scopus 로고
    • www.ClinicalTrials.gov. Phase 1 study of the safety, reactogenicity and immunogenicity of AMA-C1/ISA 720: Blood stage vaccine for Plasmodium falciparum 2009; NCT00487916.
    • www.ClinicalTrials.gov. Phase 1 study of the safety, reactogenicity and immunogenicity of AMA-C1/ISA 720: Blood stage vaccine for Plasmodium falciparum 2009; NCT00487916.
  • 61
    • 55049101497 scopus 로고    scopus 로고
    • Production, quality control, stability and pharmacotoxicity of cGMPproduced Plasmodium falciparum AMA1 FVO strain ectodomain expressed in Pichia pastoris
    • Faber BW, Remarque EJ, Kocken CH, Cheront P, Cingolani D, Xhonneux F, et al. Production, quality control, stability and pharmacotoxicity of cGMPproduced Plasmodium falciparum AMA1 FVO strain ectodomain expressed in Pichia pastoris. Vaccine 2008; 26:6143-50.
    • (2008) Vaccine , vol.26 , pp. 6143-6150
    • Faber, B.W.1    Remarque, E.J.2    Kocken, C.H.3    Cheront, P.4    Cingolani, D.5    Xhonneux, F.6
  • 62
    • 58049090288 scopus 로고    scopus 로고
    • Safety and immunogenicity of a recombinant Plasmodium falciparum AMA1 malaria vaccine adjuvanted with Alhydrogel, Montanide ISA 720 or AS02
    • Roestenberg M, Remarque E, de Jonge E, Hermsen R, Blythman H, Leroy O, et al. Safety and immunogenicity of a recombinant Plasmodium falciparum AMA1 malaria vaccine adjuvanted with Alhydrogel, Montanide ISA 720 or AS02. PLoS One 2008; 3:3960.
    • (2008) PLoS One , vol.3 , pp. 3960
    • Roestenberg, M.1    Remarque, E.2    de Jonge, E.3    Hermsen, R.4    Blythman, H.5    Leroy, O.6
  • 63
    • 0028787999 scopus 로고
    • Safety, immunogenicity and pilot efficacy of Plasmodium falciparum sporozoite and asexual blood-stage combination vaccine in Swiss adults
    • Sturchler D, Berger R, Rudin C, Just M, Saul A, Rzepczyk C, et al. Safety, immunogenicity and pilot efficacy of Plasmodium falciparum sporozoite and asexual blood-stage combination vaccine in Swiss adults. Am J Trop Med Hyg 1995; 53:423-31.
    • (1995) Am J Trop Med Hyg , vol.53 , pp. 423-431
    • Sturchler, D.1    Berger, R.2    Rudin, C.3    Just, M.4    Saul, A.5    Rzepczyk, C.6
  • 64
    • 0033529701 scopus 로고    scopus 로고
    • Human phase I vaccine trials of 3 recombinant asexual stage malaria antigens with Montanide ISA 720 adjuvant
    • Saul A, Lawrence G, Smillie A, Rzepczyk CM, Reed C, Taylor D, et al. Human phase I vaccine trials of 3 recombinant asexual stage malaria antigens with Montanide ISA 720 adjuvant. Vaccine 1999; 17:3145-59.
    • (1999) Vaccine , vol.17 , pp. 3145-3159
    • Saul, A.1    Lawrence, G.2    Smillie, A.3    Rzepczyk, C.M.4    Reed, C.5    Taylor, D.6
  • 65
    • 0034701833 scopus 로고    scopus 로고
    • Safety and immunogenicity of a threecomponent blood-stage malaria vaccine in adults living in an endemic area of Papua New Guinea
    • Genton B, Al-Yaman F, Anders R, Saul A, Brown G, Pye D, et al. Safety and immunogenicity of a threecomponent blood-stage malaria vaccine in adults living in an endemic area of Papua New Guinea. Vaccine 2000; 18:2504-11.
    • (2000) Vaccine , vol.18 , pp. 2504-2511
    • Genton, B.1    Al-Yaman, F.2    Anders, R.3    Saul, A.4    Brown, G.5    Pye, D.6
  • 66
    • 0034001440 scopus 로고    scopus 로고
    • Effect of vaccination with 3 recombinant asexual-stage malaria antigens on initial growth rates of Plasmodium falciparum in nonimmune volunteers
    • Lawrence G, Cheng QQ, Reed C, Taylor D, Stowers A, Cloonan N, et al. Effect of vaccination with 3 recombinant asexual-stage malaria antigens on initial growth rates of Plasmodium falciparum in nonimmune volunteers. Vaccine 2000; 18:1925-31.
    • (2000) Vaccine , vol.18 , pp. 1925-1931
    • Lawrence, G.1    Cheng, Q.Q.2    Reed, C.3    Taylor, D.4    Stowers, A.5    Cloonan, N.6
  • 67
    • 10744225159 scopus 로고    scopus 로고
    • Safety and immunogenicity of a threecomponent blood-stage malaria vaccine (MSP1, MSP2, RESA) against Plasmodium falciparum in Papua New Guinean children
    • Genton B, Al-Yaman F, Betuela I, Anders RF, Saul A, Baea K, et al. Safety and immunogenicity of a threecomponent blood-stage malaria vaccine (MSP1, MSP2, RESA) against Plasmodium falciparum in Papua New Guinean children. Vaccine 2003; 22:30-41.
    • (2003) Vaccine , vol.22 , pp. 30-41
    • Genton, B.1    Al-Yaman, F.2    Betuela, I.3    Anders, R.F.4    Saul, A.5    Baea, K.6
  • 68
    • 74949124220 scopus 로고    scopus 로고
    • www.anzctr.org.au. Safety and tolerability trial of a randomised, placebo-controlled MSP2-C1/ISA 720 malaria vaccine in healthy volunteers. 2007; ACTN12607000552482.
    • www.anzctr.org.au. Safety and tolerability trial of a randomised, placebo-controlled MSP2-C1/ISA 720 malaria vaccine in healthy volunteers. 2007; ACTN12607000552482.
  • 69
    • 2442626574 scopus 로고    scopus 로고
    • Fusion of two malaria vaccine candidate antigens enhances product yield, immunogenicity and antibody-mediated inhibition of parasite growth in vitro
    • Pan W, Huang D, Zhang Q, Qu L, Zhang D, Zhang X, et al. Fusion of two malaria vaccine candidate antigens enhances product yield, immunogenicity and antibody-mediated inhibition of parasite growth in vitro. J Immunol 2004; 172:6167-74.
    • (2004) J Immunol , vol.172 , pp. 6167-6174
    • Pan, W.1    Huang, D.2    Zhang, Q.3    Qu, L.4    Zhang, D.5    Zhang, X.6
  • 70
    • 56949090515 scopus 로고    scopus 로고
    • A phase 1 trial of PfCP2.9: An AMA1/MSP1 chimeric recombinant protein vaccine for Plasmodium falciparum malaria
    • Malkin E, Hu J, Li Z, Chen Z, Bi X, Reed Z, et al. A phase 1 trial of PfCP2.9: an AMA1/MSP1 chimeric recombinant protein vaccine for Plasmodium falciparum malaria. Vaccine 2008; 26:6864-73.
    • (2008) Vaccine , vol.26 , pp. 6864-6873
    • Malkin, E.1    Hu, J.2    Li, Z.3    Chen, Z.4    Bi, X.5    Reed, Z.6
  • 71
    • 44849120805 scopus 로고    scopus 로고
    • Safety and immunogenicity of a malaria vaccine, Plasmodium falciparum AMA-1/MSP-1 chimeric protein formulated in montanide ISA 720 in healthy adults
    • Hu J, Chen Z, Gu J, Wan M, Shen Q, Kieny MP, et al. Safety and immunogenicity of a malaria vaccine, Plasmodium falciparum AMA-1/MSP-1 chimeric protein formulated in montanide ISA 720 in healthy adults. PLoS One 2008; 3:1952.
    • (2008) PLoS One , vol.3 , pp. 1952
    • Hu, J.1    Chen, Z.2    Gu, J.3    Wan, M.4    Shen, Q.5    Kieny, M.P.6
  • 72
    • 1542301040 scopus 로고    scopus 로고
    • A Plasmodium falciparum GLURP-MSP3 chimeric protein; expression in Lactococcus lactis, immunogenicity and induction of biologically active antibodies
    • Theisen M, Soe S, Brunstedt K, Follmann F, Bredmose L, Israelsen H, et al. A Plasmodium falciparum GLURP-MSP3 chimeric protein; expression in Lactococcus lactis, immunogenicity and induction of biologically active antibodies. Vaccine 2004; 22:1188-98.
    • (2004) Vaccine , vol.22 , pp. 1188-1198
    • Theisen, M.1    Soe, S.2    Brunstedt, K.3    Follmann, F.4    Bredmose, L.5    Israelsen, H.6
  • 73
    • 4344561703 scopus 로고    scopus 로고
    • Identification of a conserved region of Plasmodium falciparum MSP3 targeted by biologically active antibodies to improve vaccine design
    • Singh S, Soe S, Mejia JP, Roussilhon C, Theisen M, Corradin G, et al. Identification of a conserved region of Plasmodium falciparum MSP3 targeted by biologically active antibodies to improve vaccine design. J Infect Dis 2004; 190:1010-8.
    • (2004) J Infect Dis , vol.190 , pp. 1010-1018
    • Singh, S.1    Soe, S.2    Mejia, J.P.3    Roussilhon, C.4    Theisen, M.5    Corradin, G.6
  • 74
    • 70350786394 scopus 로고    scopus 로고
    • Safety and immunogenicity of GMZ2-a MSP3-GLURP fusion protein malaria vaccine candidate
    • Esen M, Kremsner PG, Schleucher R, Gassler M, Imoukhuede EB, Imbault N, et al. Safety and immunogenicity of GMZ2-a MSP3-GLURP fusion protein malaria vaccine candidate. Vaccine 2009; 27:6862-8.
    • (2009) Vaccine , vol.27 , pp. 6862-6868
    • Esen, M.1    Kremsner, P.G.2    Schleucher, R.3    Gassler, M.4    Imoukhuede, E.B.5    Imbault, N.6
  • 75
    • 74949128401 scopus 로고    scopus 로고
    • www.ClinicalTrials.gov. Safety of recombinant hybrid GMZ2 (GLURP + MSP3) blood stage malaria vaccine. 2008; NCT00424944.
    • www.ClinicalTrials.gov. Safety of recombinant hybrid GMZ2 (GLURP + MSP3) blood stage malaria vaccine. 2008; NCT00424944.
  • 76
    • 74949111101 scopus 로고    scopus 로고
    • www.ClinicalTrials.gov. Safety and immunogenicity of 30 and 100 ug of GMZ2 in Gabonese children aged 1-5 years. 2008; NCT00703066.
    • www.ClinicalTrials.gov. Safety and immunogenicity of 30 and 100 ug of GMZ2 in Gabonese children aged 1-5 years. 2008; NCT00703066.
  • 77
    • 33947107414 scopus 로고    scopus 로고
    • Glutamate-rich protein (GLURP) induces antibodies that inhibit in vitro growth of Plasmodium falciparum in a phase 1 malaria vaccine trial
    • Hermsen CC, Verhage DF, Telgt DS, Teelen K, Bousema JT, Roestenberg M, et al. Glutamate-rich protein (GLURP) induces antibodies that inhibit in vitro growth of Plasmodium falciparum in a phase 1 malaria vaccine trial. Vaccine 2007; 25:2930-40.
    • (2007) Vaccine , vol.25 , pp. 2930-2940
    • Hermsen, C.C.1    Verhage, D.F.2    Telgt, D.S.3    Teelen, K.4    Bousema, J.T.5    Roestenberg, M.6
  • 78
    • 28444478057 scopus 로고    scopus 로고
    • Phase I malaria vaccine trial with a long synthetic peptide derived from the merozoite surface protein 3 antigen
    • Audran R, Cachat M, Lurati F, Soe S, Leroy O, Corradin G, et al. Phase I malaria vaccine trial with a long synthetic peptide derived from the merozoite surface protein 3 antigen. Infect Immun 2005; 73:8017-26.
    • (2005) Infect Immun , vol.73 , pp. 8017-8026
    • Audran, R.1    Cachat, M.2    Lurati, F.3    Soe, S.4    Leroy, O.5    Corradin, G.6
  • 79
    • 33947114334 scopus 로고    scopus 로고
    • Safety and immunogenicity of the Plasmodium falciparum merozoite surface protein-3 long synthetic peptide (MSP3-LSP) malaria vaccine in healthy, semi-immune adult males in Burkina Faso, West Africa
    • Sirima SB, Nebie I, Ouedraogo A, Tiono AB, Konate AT, Gansane A, et al. Safety and immunogenicity of the Plasmodium falciparum merozoite surface protein-3 long synthetic peptide (MSP3-LSP) malaria vaccine in healthy, semi-immune adult males in Burkina Faso, West Africa. Vaccine 2007; 25:2723-32.
    • (2007) Vaccine , vol.25 , pp. 2723-2732
    • Sirima, S.B.1    Nebie, I.2    Ouedraogo, A.3    Tiono, A.B.4    Konate, A.T.5    Gansane, A.6
  • 80
    • 74949093614 scopus 로고    scopus 로고
    • www.ClinicalTrials.gov. Safety and immunogenicity og EBA-175 RII-NG malaria vaccine administered intramuscularly. 2009; NCT00347555.
    • www.ClinicalTrials.gov. Safety and immunogenicity og EBA-175 RII-NG malaria vaccine administered intramuscularly. 2009; NCT00347555.
  • 81
    • 56149086750 scopus 로고    scopus 로고
    • Malaria vaccine
    • Horii T. Malaria vaccine. Nippon Rinsho 2008; 66:1990-8.
    • (2008) Nippon Rinsho , vol.66 , pp. 1990-1998
    • Horii, T.1
  • 82
    • 33646344203 scopus 로고    scopus 로고
    • Harbouring in the brain: A focus on immune evasion mechanisms and their deleterious effects in malaria and human African trypanosomiasis
    • Bisser S, Ouwe-Missi-Oukem-Boyer ON, Toure FS, Taoufiq Z, Bouteille B, Buguet A, et al. Harbouring in the brain: A focus on immune evasion mechanisms and their deleterious effects in malaria and human African trypanosomiasis. Int J Parasitol 2006; 36:529-40.
    • (2006) Int J Parasitol , vol.36 , pp. 529-540
    • Bisser, S.1    Ouwe-Missi-Oukem-Boyer, O.N.2    Toure, F.S.3    Taoufiq, Z.4    Bouteille, B.5    Buguet, A.6
  • 84
    • 0035058431 scopus 로고    scopus 로고
    • Specificity of the protective antibody response to apical membrane antigen 1
    • Hodder AN, Crewther PE, Anders RF. Specificity of the protective antibody response to apical membrane antigen 1. Infect Immun 2001; 69:3286-94.
    • (2001) Infect Immun , vol.69 , pp. 3286-3294
    • Hodder, A.N.1    Crewther, P.E.2    Anders, R.F.3
  • 85
    • 36749073862 scopus 로고    scopus 로고
    • In immunization with Plasmodium falciparum apical membrane antigen 1, the specificity of antibodies depends on the species immunized
    • Miura K, Zhou H, Muratova OV, Orcutt AC, Giersing B, Miller LH, et al. In immunization with Plasmodium falciparum apical membrane antigen 1, the specificity of antibodies depends on the species immunized. Infect Immun 2007; 75:5827-36.
    • (2007) Infect Immun , vol.75 , pp. 5827-5836
    • Miura, K.1    Zhou, H.2    Muratova, O.V.3    Orcutt, A.C.4    Giersing, B.5    Miller, L.H.6
  • 86
    • 50949124044 scopus 로고    scopus 로고
    • Protection induced by Plasmodium falciparum MSP1(42) is strain-specific, antigen and adjuvant dependent, and correlates with antibody responses
    • Lyon JA, Angov E, Fay MP, Sullivan JS, Girourd AS, Robinson SJ, et al. Protection induced by Plasmodium falciparum MSP1(42) is strain-specific, antigen and adjuvant dependent, and correlates with antibody responses. PLoS One 2008; 3:2830.
    • (2008) PLoS One , vol.3 , pp. 2830
    • Lyon, J.A.1    Angov, E.2    Fay, M.P.3    Sullivan, J.S.4    Girourd, A.S.5    Robinson, S.J.6
  • 87
    • 60349121929 scopus 로고    scopus 로고
    • Comparison of immunogenicity of five MSP1-based malaria vaccine candidate antigens in rabbits
    • Reed ZH, Kieny MP, Engers H, Friede M, Chang S, Longacre S, et al. Comparison of immunogenicity of five MSP1-based malaria vaccine candidate antigens in rabbits. Vaccine 2009; 27:1651-60.
    • (2009) Vaccine , vol.27 , pp. 1651-1660
    • Reed, Z.H.1    Kieny, M.P.2    Engers, H.3    Friede, M.4    Chang, S.5    Longacre, S.6
  • 88
    • 72449139057 scopus 로고    scopus 로고
    • Inhibition of erythrocyte invasion and Plasmodium falciparum Merozoite Surface Protein 1 processing by human IgG1 and IgG3 antibodies
    • Lazarou M, Guevara Patino JA, Jennings RM, McIntosh RS, Shi J, Howell S, et al. Inhibition of erythrocyte invasion and Plasmodium falciparum Merozoite Surface Protein 1 processing by human IgG1 and IgG3 antibodies. Infect Immun 2009.
    • (2009) Infect Immun
    • Lazarou, M.1    Guevara Patino, J.A.2    Jennings, R.M.3    McIntosh, R.S.4    Shi, J.5    Howell, S.6
  • 89
    • 38149101775 scopus 로고    scopus 로고
    • Variation in use of erythrocyte invasion pathways by Plasmodium falciparum mediates evasion of human inhibitory antibodies
    • Persson KE, McCallum FJ, Reiling L, Lister NA, Stubbs J, Cowman AF, et al. Variation in use of erythrocyte invasion pathways by Plasmodium falciparum mediates evasion of human inhibitory antibodies. J Clin Invest 2008; 118:342-51.
    • (2008) J Clin Invest , vol.118 , pp. 342-351
    • Persson, K.E.1    McCallum, F.J.2    Reiling, L.3    Lister, N.A.4    Stubbs, J.5    Cowman, A.F.6
  • 90
    • 0036892213 scopus 로고    scopus 로고
    • In vitro studies with recombinant Plasmodium falciparum apical membrane antigen 1 (AMA1): Production and activity of an AMA1 vaccine and generation of a multiallelic response
    • Kennedy MC, Wang J, Zhang Y, Miles AP, Chitsaz F, Saul A, et al. In vitro studies with recombinant Plasmodium falciparum apical membrane antigen 1 (AMA1): production and activity of an AMA1 vaccine and generation of a multiallelic response. Infect Immun 2002; 70:6948-60.
    • (2002) Infect Immun , vol.70 , pp. 6948-6960
    • Kennedy, M.C.1    Wang, J.2    Zhang, Y.3    Miles, A.P.4    Chitsaz, F.5    Saul, A.6
  • 91
    • 0036073678 scopus 로고    scopus 로고
    • High-level expression of the malaria blood-stage vaccine candidate Plasmodium falciparum apical membrane antigen 1 and induction of antibodies that inhibit erythrocyte invasion
    • Kocken CH, Withers-Martinez C, Dubbeld MA, van der Wel A, Hackett F, Valderrama A, et al. High-level expression of the malaria blood-stage vaccine candidate Plasmodium falciparum apical membrane antigen 1 and induction of antibodies that inhibit erythrocyte invasion. Infect Immun 2002; 70:4471-6.
    • (2002) Infect Immun , vol.70 , pp. 4471-4476
    • Kocken, C.H.1    Withers-Martinez, C.2    Dubbeld, M.A.3    van der Wel, A.4    Hackett, F.5    Valderrama, A.6
  • 92
    • 74949118446 scopus 로고    scopus 로고
    • High antibody titer against apical membrane antigen-1 is required to protect against malaria in the Aotus model
    • Dutta S, Sullivan JS, Grady KK, Haynes JD, Komisar J, Batchelor AH, et al. High antibody titer against apical membrane antigen-1 is required to protect against malaria in the Aotus model. PLoS One 2009; 4:e8138.
    • (2009) PLoS One , vol.4
    • Dutta, S.1    Sullivan, J.S.2    Grady, K.K.3    Haynes, J.D.4    Komisar, J.5    Batchelor, A.H.6
  • 93
    • 0029098383 scopus 로고
    • Mechanisms underlying the monocyte-mediated antibody-dependent killing of Plasmodium falciparum asexual blood stages
    • Bouharoun-Tayoun H, Oeuvray C, Lunel F, Druilhe P. Mechanisms underlying the monocyte-mediated antibody-dependent killing of Plasmodium falciparum asexual blood stages. J Exp Med 1995; 182:409-18.
    • (1995) J Exp Med , vol.182 , pp. 409-418
    • Bouharoun-Tayoun, H.1    Oeuvray, C.2    Lunel, F.3    Druilhe, P.4
  • 94
    • 0034666704 scopus 로고    scopus 로고
    • Identification of a major B-cell epitope of the Plasmodium falciparum glutamate-rich protein (GLURP), targeted by human antibodies mediating parasite killing
    • Theisen M, Soe S, Jessing SG, Okkels LM, Danielsen S, Oeuvray C, et al. Identification of a major B-cell epitope of the Plasmodium falciparum glutamate-rich protein (GLURP), targeted by human antibodies mediating parasite killing. Vaccine 2000; 19:204-12.
    • (2000) Vaccine , vol.19 , pp. 204-212
    • Theisen, M.1    Soe, S.2    Jessing, S.G.3    Okkels, L.M.4    Danielsen, S.5    Oeuvray, C.6
  • 95
    • 0023110710 scopus 로고
    • Epidemiological correlation between levels of antibodies promoting merozoite phagocytosis of Plasmodium falciparum and malariaimmune status
    • Druilhe P, Khusmith S. Epidemiological correlation between levels of antibodies promoting merozoite phagocytosis of Plasmodium falciparum and malariaimmune status. Infect Immun 1987; 55:888-91.
    • (1987) Infect Immun , vol.55 , pp. 888-891
    • Druilhe, P.1    Khusmith, S.2
  • 96
    • 0031895495 scopus 로고    scopus 로고
    • IgG3 antibodies to Plasmodium falciparum merozoite surface protein 2 (MSP2): Increasing prevalence with age and association with clinical immunity to malaria
    • Taylor RR, Allen SJ, Greenwood BM, Riley EM. IgG3 antibodies to Plasmodium falciparum merozoite surface protein 2 (MSP2): increasing prevalence with age and association with clinical immunity to malaria. Am J Trop Med Hyg 1998; 58:406-13.
    • (1998) Am J Trop Med Hyg , vol.58 , pp. 406-413
    • Taylor, R.R.1    Allen, S.J.2    Greenwood, B.M.3    Riley, E.M.4
  • 97
    • 0034064657 scopus 로고    scopus 로고
    • Cytophilic immunoglobulin responses to Plasmodium falciparum glutamate-rich protein are correlated with protection against clinical malaria in Dielmo, Senegal
    • Oeuvray C, Theisen M, Rogier C, Trape JF, Jepsen S, Druilhe P. Cytophilic immunoglobulin responses to Plasmodium falciparum glutamate-rich protein are correlated with protection against clinical malaria in Dielmo, Senegal. Infect Immun 2000; 68:2617-20.
    • (2000) Infect Immun , vol.68 , pp. 2617-2620
    • Oeuvray, C.1    Theisen, M.2    Rogier, C.3    Trape, J.F.4    Jepsen, S.5    Druilhe, P.6
  • 98
    • 70449584531 scopus 로고    scopus 로고
    • The quantity and quality of African children's IgG responses to merozoite surface antigens reflect protection against Plasmodium falciparum malaria
    • Courtin D, Oesterholt M, Huismans H, Kusi K, Milet J, Badaut C, et al. The quantity and quality of African children's IgG responses to merozoite surface antigens reflect protection against Plasmodium falciparum malaria. PLoS One 2009; 4:7590.
    • (2009) PLoS One , vol.4 , pp. 7590
    • Courtin, D.1    Oesterholt, M.2    Huismans, H.3    Kusi, K.4    Milet, J.5    Badaut, C.6
  • 99
    • 0036119386 scopus 로고    scopus 로고
    • Naturally acquired immunoglobulin (Ig) G subclass antibodies to crude asexual Plasmodium falciparum lysates: Evidence for association with protection for IgG1 and disease for IgG2
    • Ndungu FM, Bull PC, Ross A, Lowe BS, Kabiru E, Marsh K. Naturally acquired immunoglobulin (Ig) G subclass antibodies to crude asexual Plasmodium falciparum lysates: evidence for association with protection for IgG1 and disease for IgG2. Parasite Immunol 2002; 24:77-82.
    • (2002) Parasite Immunol , vol.24 , pp. 77-82
    • Ndungu, F.M.1    Bull, P.C.2    Ross, A.3    Lowe, B.S.4    Kabiru, E.5    Marsh, K.6
  • 100
    • 35748949254 scopus 로고    scopus 로고
    • Structure of an IgNAR-AMA1 complex: Targeting a conserved hydrophobic cleft broadens malarial strain recognition
    • Henderson KA, Streltsov VA, Coley AM, Dolezal O, Hudson PJ, Batchelor AH, et al. Structure of an IgNAR-AMA1 complex: targeting a conserved hydrophobic cleft broadens malarial strain recognition. Structure 2007; 15:1452-66.
    • (2007) Structure , vol.15 , pp. 1452-1466
    • Henderson, K.A.1    Streltsov, V.A.2    Coley, A.M.3    Dolezal, O.4    Hudson, P.J.5    Batchelor, A.H.6
  • 101
    • 37349008490 scopus 로고    scopus 로고
    • Structure of the malaria antigen AMA1 in complex with a growth-inhibitory antibody
    • Coley AM, Gupta A, Murphy VJ, Bai T, Kim H, Foley M, et al. Structure of the malaria antigen AMA1 in complex with a growth-inhibitory antibody. PLoS Pathog 2007; 3:1308-19.
    • (2007) PLoS Pathog , vol.3 , pp. 1308-1319
    • Coley, A.M.1    Gupta, A.2    Murphy, V.J.3    Bai, T.4    Kim, H.5    Foley, M.6
  • 102
    • 34147169102 scopus 로고    scopus 로고
    • Fine mapping of an epitope recognized by an invasioninhibitory monoclonal antibody on the malaria vaccine candidate apical membrane antigen 1
    • Collins CR, Withers-Martinez C, Bentley GA, Batchelor AH, Thomas AW, Blackman MJ. Fine mapping of an epitope recognized by an invasioninhibitory monoclonal antibody on the malaria vaccine candidate apical membrane antigen 1. J Biol Chem 2007; 282:7431-41.
    • (2007) J Biol Chem , vol.282 , pp. 7431-7441
    • Collins, C.R.1    Withers-Martinez, C.2    Bentley, G.A.3    Batchelor, A.H.4    Thomas, A.W.5    Blackman, M.J.6
  • 104
    • 45849091898 scopus 로고    scopus 로고
    • Preclinical profiling of the immunogenicity of a two-component subunit malaria vaccine candidate based on virosome technology
    • Okitsu SL, Mueller MS, Amacker M, Vogel D, Westerfeld N, Robinson JA, et al. Preclinical profiling of the immunogenicity of a two-component subunit malaria vaccine candidate based on virosome technology. Hum Vaccin 2008; 4:106-14.
    • (2008) Hum Vaccin , vol.4 , pp. 106-114
    • Okitsu, S.L.1    Mueller, M.S.2    Amacker, M.3    Vogel, D.4    Westerfeld, N.5    Robinson, J.A.6
  • 105
    • 42949156106 scopus 로고    scopus 로고
    • Evidence of blood stage efficacy with a virosomal malaria vaccine in a phase IIa clinical trial
    • Thompson FM, Porter DW, Okitsu SL, Westerfeld N, Vogel D, Todryk S, et al. Evidence of blood stage efficacy with a virosomal malaria vaccine in a phase IIa clinical trial. PLoS One 2008; 3:1493.
    • (2008) PLoS One , vol.3 , pp. 1493
    • Thompson, F.M.1    Porter, D.W.2    Okitsu, S.L.3    Westerfeld, N.4    Vogel, D.5    Todryk, S.6
  • 107
    • 0345283125 scopus 로고    scopus 로고
    • Biochemical and immunological characterization of bacterially expressed and refolded Plasmodium falciparum 42-kilodalton C-terminal merozoite surface protein 1
    • Singh S, Kennedy MC, Long CA, Saul AJ, Miller LH, Stowers AW. Biochemical and immunological characterization of bacterially expressed and refolded Plasmodium falciparum 42-kilodalton C-terminal merozoite surface protein 1. Infect Immun 2003; 71:6766-74.
    • (2003) Infect Immun , vol.71 , pp. 6766-6774
    • Singh, S.1    Kennedy, M.C.2    Long, C.A.3    Saul, A.J.4    Miller, L.H.5    Stowers, A.W.6
  • 109
    • 0035903097 scopus 로고    scopus 로고
    • Proteolytic processing and primary structure of Plasmodium falciparum apical membrane antigen-1
    • Howell SA, Withers-Martinez C, Kocken CH, Thomas AW, Blackman MJ. Proteolytic processing and primary structure of Plasmodium falciparum apical membrane antigen-1. J Biol Chem 2001; 276:31311-20.
    • (2001) J Biol Chem , vol.276 , pp. 31311-31320
    • Howell, S.A.1    Withers-Martinez, C.2    Kocken, C.H.3    Thomas, A.W.4    Blackman, M.J.5
  • 110
    • 0033636201 scopus 로고    scopus 로고
    • Apical membrane antigen 1 plays a central role in erythrocyte invasion by Plasmodium species
    • Triglia T, Healer J, Caruana SR, Hodder AN, Anders RF, Crabb BS, et al. Apical membrane antigen 1 plays a central role in erythrocyte invasion by Plasmodium species. Mol Microbiol 2000; 38:706-18.
    • (2000) Mol Microbiol , vol.38 , pp. 706-718
    • Triglia, T.1    Healer, J.2    Caruana, S.R.3    Hodder, A.N.4    Anders, R.F.5    Crabb, B.S.6
  • 111
    • 10744226228 scopus 로고    scopus 로고
    • A role for apical membrane antigen 1 during invasion of hepatocytes by Plasmodium falciparum sporozoites
    • Silvie O, Franetich JF, Charrin S, Mueller MS, Siau A, Bodescot M, et al. A role for apical membrane antigen 1 during invasion of hepatocytes by Plasmodium falciparum sporozoites. J Biol Chem 2004; 279:9490-6.
    • (2004) J Biol Chem , vol.279 , pp. 9490-9496
    • Silvie, O.1    Franetich, J.F.2    Charrin, S.3    Mueller, M.S.4    Siau, A.5    Bodescot, M.6
  • 112
    • 0036784706 scopus 로고    scopus 로고
    • Independent translocation of two micronemal proteins in developing Plasmodium falciparum merozoites
    • Healer J, Crawford S, Ralph S, McFadden G, Cowman AF. Independent translocation of two micronemal proteins in developing Plasmodium falciparum merozoites. Infect Immun 2002; 70:5751-8.
    • (2002) Infect Immun , vol.70 , pp. 5751-5758
    • Healer, J.1    Crawford, S.2    Ralph, S.3    McFadden, G.4    Cowman, A.F.5
  • 113
    • 0141502116 scopus 로고    scopus 로고
    • Plasmodium falciparum apical membrane antigen 1 (PfAMA-1) is translocated within micronemes along subpellicular microtubules during merozoite development
    • Bannister LH, Hopkins JM, Dluzewski AR, Margos G, Williams IT, Blackman MJ, et al. Plasmodium falciparum apical membrane antigen 1 (PfAMA-1) is translocated within micronemes along subpellicular microtubules during merozoite development. J Cell Sci 2003; 116:3825-34.
    • (2003) J Cell Sci , vol.116 , pp. 3825-3834
    • Bannister, L.H.1    Hopkins, J.M.2    Dluzewski, A.R.3    Margos, G.4    Williams, I.T.5    Blackman, M.J.6
  • 114
    • 0028145547 scopus 로고
    • Differential localization of full-length and processed forms of PF83/AMA-1 an apical membrane antigen of Plasmodium falciparum merozoites
    • Narum DL, Thomas AW. Differential localization of full-length and processed forms of PF83/AMA-1 an apical membrane antigen of Plasmodium falciparum merozoites. Mol Biochem Parasitol 1994; 67:59-68.
    • (1994) Mol Biochem Parasitol , vol.67 , pp. 59-68
    • Narum, D.L.1    Thomas, A.W.2
  • 115
    • 59249106253 scopus 로고    scopus 로고
    • Collins CR, Withers-Martinez C, Hackett F, Blackman MJ. An inhibitory antibody blocks interactions between components of the malarial invasion machinery. PLoS Pathog 2009; 5:1000273.
    • Collins CR, Withers-Martinez C, Hackett F, Blackman MJ. An inhibitory antibody blocks interactions between components of the malarial invasion machinery. PLoS Pathog 2009; 5:1000273.
  • 116
    • 0028589444 scopus 로고
    • Protective immunity induced in squirrel monkeys with recombinant apical membrane antigen-1 of Plasmodium fragile
    • Collins WE, Pye D, Crewther PE, Vandenberg KL, Galland GG, Sulzer AJ, et al. Protective immunity induced in squirrel monkeys with recombinant apical membrane antigen-1 of Plasmodium fragile. Am J Trop Med Hyg 1994; 51:711-9.
    • (1994) Am J Trop Med Hyg , vol.51 , pp. 711-719
    • Collins, W.E.1    Pye, D.2    Crewther, P.E.3    Vandenberg, K.L.4    Galland, G.G.5    Sulzer, A.J.6
  • 117
    • 0036893441 scopus 로고    scopus 로고
    • Vaccination of monkeys with recombinant Plasmodium falciparum apical membrane antigen 1 confers protection against blood-stage malaria
    • Stowers AW, Kennedy MC, Keegan BP, Saul A, Long CA, Miller LH. Vaccination of monkeys with recombinant Plasmodium falciparum apical membrane antigen 1 confers protection against blood-stage malaria. Infect Immun 2002; 70:6961-7.
    • (2002) Infect Immun , vol.70 , pp. 6961-6967
    • Stowers, A.W.1    Kennedy, M.C.2    Keegan, B.P.3    Saul, A.4    Long, C.A.5    Miller, L.H.6
  • 118
    • 74949118446 scopus 로고    scopus 로고
    • Dutta S, Sullivan JS, Grady KK, Haynes JD, Komisar J, Batchelor A, et al. High antibody titer against apical membrane antigen-1 is required to protect against malaria in the Aotus model. PLoS One 2009; in press.
    • Dutta S, Sullivan JS, Grady KK, Haynes JD, Komisar J, Batchelor A, et al. High antibody titer against apical membrane antigen-1 is required to protect against malaria in the Aotus model. PLoS One 2009; in press.
  • 119
    • 0031986201 scopus 로고    scopus 로고
    • Immunisation with recombinant AMA-1 protects mice against infection with Plasmodium chabaudi
    • Anders RF, Crewther PE, Edwards S, Margetts M, Matthew ML, Pollock B, et al. Immunisation with recombinant AMA-1 protects mice against infection with Plasmodium chabaudi. Vaccine 1998; 16:240-7.
    • (1998) Vaccine , vol.16 , pp. 240-247
    • Anders, R.F.1    Crewther, P.E.2    Edwards, S.3    Margetts, M.4    Matthew, M.L.5    Pollock, B.6
  • 120
    • 0030017335 scopus 로고    scopus 로고
    • Protective immune responses to apical membrane antigen 1 of Plasmodium chabaudi involve recognition of strain-specific epitopes
    • Crewther PE, Matthew ML, Flegg RH, Anders RF. Protective immune responses to apical membrane antigen 1 of Plasmodium chabaudi involve recognition of strain-specific epitopes. Infect Immun 1996; 64:3310-7.
    • (1996) Infect Immun , vol.64 , pp. 3310-3317
    • Crewther, P.E.1    Matthew, M.L.2    Flegg, R.H.3    Anders, R.F.4
  • 121
    • 4644359502 scopus 로고    scopus 로고
    • Protection against Plasmodium chabaudi malaria induced by immunization with apical membrane antigen 1 and merozoite surface protein 1 in the absence of gamma interferon or interleukin-4
    • Burns JM Jr, Flaherty PR, Nanavati P, Weidanz WP. Protection against Plasmodium chabaudi malaria induced by immunization with apical membrane antigen 1 and merozoite surface protein 1 in the absence of gamma interferon or interleukin-4. Infect Immun 2004; 72:5605-12.
    • (2004) Infect Immun , vol.72 , pp. 5605-5612
    • Burns Jr, J.M.1    Flaherty, P.R.2    Nanavati, P.3    Weidanz, W.P.4
  • 122
    • 0037449076 scopus 로고    scopus 로고
    • Immunization against Plasmodium chabaudi malaria using combined formulations of apical membrane antigen-1 and merozoite surface protein-1
    • Burns JM Jr, Flaherty PR, Romero MM, Weidanz WP. Immunization against Plasmodium chabaudi malaria using combined formulations of apical membrane antigen-1 and merozoite surface protein-1. Vaccine 2003; 21:1843-52.
    • (2003) Vaccine , vol.21 , pp. 1843-1852
    • Burns Jr, J.M.1    Flaherty, P.R.2    Romero, M.M.3    Weidanz, W.P.4
  • 123
    • 0034095455 scopus 로고    scopus 로고
    • Immunization with parasite-derived apical membrane antigen 1 or passive immunization with a specific monoclonal antibody protects BALB/c mice against lethal Plasmodium yoelii yoelii YM bloodstage infection
    • Narum DL, Ogun SA, Thomas AW, Holder AA. Immunization with parasite-derived apical membrane antigen 1 or passive immunization with a specific monoclonal antibody protects BALB/c mice against lethal Plasmodium yoelii yoelii YM bloodstage infection. Infect Immun 2000; 68:2899-906.
    • (2000) Infect Immun , vol.68 , pp. 2899-2906
    • Narum, D.L.1    Ogun, S.A.2    Thomas, A.W.3    Holder, A.A.4
  • 124
    • 0023769849 scopus 로고
    • Vaccination trials in rhesus monkeys with a minor, invariant, Plasmodium knowlesi 66 kD merozoite antigen
    • Deans JA, Knight AM, Jean WC, Waters AP, Cohen S, Mitchell GH. Vaccination trials in rhesus monkeys with a minor, invariant, Plasmodium knowlesi 66 kD merozoite antigen. Parasite Immunol 1988; 10:535-52.
    • (1988) Parasite Immunol , vol.10 , pp. 535-552
    • Deans, J.A.1    Knight, A.M.2    Jean, W.C.3    Waters, A.P.4    Cohen, S.5    Mitchell, G.H.6
  • 125
    • 0034235312 scopus 로고    scopus 로고
    • + T cells acting independently of antibody contribute to protective immunity to Plasmodium chabaudi infection after apical membrane antigen 1 immunization
    • + T cells acting independently of antibody contribute to protective immunity to Plasmodium chabaudi infection after apical membrane antigen 1 immunization. J Immunol 2000; 165:389-96.
    • (2000) J Immunol , vol.165 , pp. 389-396
    • Xu, H.1    Hodder, A.N.2    Yan, H.3    Crewther, P.E.4    Anders, R.F.5    Good, M.F.6
  • 126
    • 0036389814 scopus 로고    scopus 로고
    • Structure of domain III of the blood-stage malaria vaccine candidate, Plasmodium falciparum apical membrane antigen 1 (AMA1)
    • Nair M, Hinds MG, Coley AM, Hodder AN, Foley M, Anders RF, et al. Structure of domain III of the blood-stage malaria vaccine candidate, Plasmodium falciparum apical membrane antigen 1 (AMA1). J Mol Biol 2002; 322:741-53.
    • (2002) J Mol Biol , vol.322 , pp. 741-753
    • Nair, M.1    Hinds, M.G.2    Coley, A.M.3    Hodder, A.N.4    Foley, M.5    Anders, R.F.6
  • 128
    • 24644523245 scopus 로고    scopus 로고
    • Structure of AMA1 from Plasmodium falciparum reveals a clustering of polymorphisms that surround a conserved hydrophobic pocket
    • Bai T, Becker M, Gupta A, Strike P, Murphy VJ, Anders RF, et al. Structure of AMA1 from Plasmodium falciparum reveals a clustering of polymorphisms that surround a conserved hydrophobic pocket. Proc Natl Acad Sci USA 2005; 102:12736-41.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 12736-12741
    • Bai, T.1    Becker, M.2    Gupta, A.3    Strike, P.4    Murphy, V.J.5    Anders, R.F.6
  • 129
    • 0035183986 scopus 로고    scopus 로고
    • Rapid and precise epitope mapping of monoclonal antibodies against Plasmodium falciparum AMA1 by combined phage display of fragments and random peptides
    • Coley AM, Campanale NV, Casey JL, Hodder AN, Crewther PE, Anders RF, et al. Rapid and precise epitope mapping of monoclonal antibodies against Plasmodium falciparum AMA1 by combined phage display of fragments and random peptides. Protein Eng 2001; 14:691-8.
    • (2001) Protein Eng , vol.14 , pp. 691-698
    • Coley, A.M.1    Campanale, N.V.2    Casey, J.L.3    Hodder, A.N.4    Crewther, P.E.5    Anders, R.F.6
  • 130
    • 33646342967 scopus 로고    scopus 로고
    • The most polymorphic residue on Plasmodium falciparum apical membrane antigen 1 determines binding of an invasion-inhibitory antibody
    • Coley AM, Parisi K, Masciantonio R, Hoeck J, Casey JL, Murphy VJ, et al. The most polymorphic residue on Plasmodium falciparum apical membrane antigen 1 determines binding of an invasion-inhibitory antibody. Infect Immun 2006; 74:2628-36.
    • (2006) Infect Immun , vol.74 , pp. 2628-2636
    • Coley, A.M.1    Parisi, K.2    Masciantonio, R.3    Hoeck, J.4    Casey, J.L.5    Murphy, V.J.6
  • 131
    • 34547647830 scopus 로고    scopus 로고
    • Structural basis of antigenic escape of a malaria vaccine candidate
    • Dutta S, Lee SY, Batchelor AH, Lanar DE. Structural basis of antigenic escape of a malaria vaccine candidate. Proc Natl Acad Sci USA 2007; 104:12488-93.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 12488-12493
    • Dutta, S.1    Lee, S.Y.2    Batchelor, A.H.3    Lanar, D.E.4
  • 132
    • 33746273843 scopus 로고    scopus 로고
    • Identification and stoichiometry of glycosylphosphatidylinositol-anchored membrane proteins of the human malaria parasite Plasmodium falciparum
    • Gilson PR, Nebl T, Vukcevic D, Moritz RL, Sargeant T, Speed TP, et al. Identification and stoichiometry of glycosylphosphatidylinositol-anchored membrane proteins of the human malaria parasite Plasmodium falciparum. Mol Cell Proteomics 2006; 5:1286-99.
    • (2006) Mol Cell Proteomics , vol.5 , pp. 1286-1299
    • Gilson, P.R.1    Nebl, T.2    Vukcevic, D.3    Moritz, R.L.4    Sargeant, T.5    Speed, T.P.6
  • 133
    • 0029869566 scopus 로고    scopus 로고
    • Structural analysis of the glycosyl-phosphatidylinositol membrane anchor of the merozoite surface proteins-1 and -2 of Plasmodium falciparum
    • Gerold P, Schofield L, Blackman MJ, Holder AA, Schwarz RT. Structural analysis of the glycosyl-phosphatidylinositol membrane anchor of the merozoite surface proteins-1 and -2 of Plasmodium falciparum. Mol Biochem Parasitol 1996; 75:131-43.
    • (1996) Mol Biochem Parasitol , vol.75 , pp. 131-143
    • Gerold, P.1    Schofield, L.2    Blackman, M.J.3    Holder, A.A.4    Schwarz, R.T.5
  • 134
    • 0032054265 scopus 로고    scopus 로고
    • Merozoite surface protein 2 of Plasmodium reichenowi is a unique mosaic of Plasmodium falciparum allelic forms and species-specific elements
    • Dubbeld MA, Kocken CH, Thomas AW. Merozoite surface protein 2 of Plasmodium reichenowi is a unique mosaic of Plasmodium falciparum allelic forms and species-specific elements. Mol Biochem Parasitol 1998; 92:187-92.
    • (1998) Mol Biochem Parasitol , vol.92 , pp. 187-192
    • Dubbeld, M.A.1    Kocken, C.H.2    Thomas, A.W.3
  • 135
    • 0037192108 scopus 로고    scopus 로고
    • Functional analysis of Plasmodium falciparum merozoite antigens: Implications for erythrocyte invasion and vaccine development
    • Cowman AF, Baldi DL, Duraisingh M, Healer J, Mills KE, O'Donnell RA, et al. Functional analysis of Plasmodium falciparum merozoite antigens: implications for erythrocyte invasion and vaccine development. Philos Trans R Soc Lond B Biol Sci 2002; 357:25-33.
    • (2002) Philos Trans R Soc Lond B Biol Sci , vol.357 , pp. 25-33
    • Cowman, A.F.1    Baldi, D.L.2    Duraisingh, M.3    Healer, J.4    Mills, K.E.5    O'Donnell, R.A.6
  • 136
    • 33745630355 scopus 로고    scopus 로고
    • A set of glycosylphosphatidyl inositol-anchored membrane proteins of Plasmodium falciparum is refractory to genetic deletion
    • Sanders PR, Kats LM, Drew DR, O'Donnell RA, O'Neill M, Maier AG, et al. A set of glycosylphosphatidyl inositol-anchored membrane proteins of Plasmodium falciparum is refractory to genetic deletion. Infect Immun 2006; 74:4330-8.
    • (2006) Infect Immun , vol.74 , pp. 4330-4338
    • Sanders, P.R.1    Kats, L.M.2    Drew, D.R.3    O'Donnell, R.A.4    O'Neill, M.5    Maier, A.G.6
  • 137
    • 0038781688 scopus 로고    scopus 로고
    • Genetic diversity and antigenic polymorphism in Plasmodium falciparum: Extensive serological cross-reactivity between allelic variants of merozoite surface protein 2
    • Franks S, Baton L, Tetteh K, Tongren E, Dewin D, Akanmori BD, et al. Genetic diversity and antigenic polymorphism in Plasmodium falciparum: extensive serological cross-reactivity between allelic variants of merozoite surface protein 2. Infect Immun 2003; 71:3485-95.
    • (2003) Infect Immun , vol.71 , pp. 3485-3495
    • Franks, S.1    Baton, L.2    Tetteh, K.3    Tongren, E.4    Dewin, D.5    Akanmori, B.D.6
  • 139
    • 0032973491 scopus 로고    scopus 로고
    • Genotypes of merozoite surface protein 2 of Plasmodium falciparum in Tanzania
    • Felger I, Irion A, Steiger S, Beck HP. Genotypes of merozoite surface protein 2 of Plasmodium falciparum in Tanzania. Trans R Soc Trop Med Hyg 1999; 93:3-9.
    • (1999) Trans R Soc Trop Med Hyg , vol.93 , pp. 3-9
    • Felger, I.1    Irion, A.2    Steiger, S.3    Beck, H.P.4
  • 140
    • 0031467164 scopus 로고    scopus 로고
    • New repeat unit and hot spot of recombination in FC27-type alleles of the gene coding for Plasmodium falciparum merozoite surface protein 2
    • Irion A, Beck HP, Felger I. New repeat unit and hot spot of recombination in FC27-type alleles of the gene coding for Plasmodium falciparum merozoite surface protein 2. Mol Biochem Parasitol 1997; 90:367-70.
    • (1997) Mol Biochem Parasitol , vol.90 , pp. 367-370
    • Irion, A.1    Beck, H.P.2    Felger, I.3
  • 142
    • 0025965056 scopus 로고
    • Structural and antigenic polymorphism of the 35- to 48-kilodalton merozoite surface antigen (MSA-2) of the malaria parasite Plasmodium falciparum
    • Fenton B, Clark JT, Khan CM, Robinson JV, Walliker D, Ridley R, et al. Structural and antigenic polymorphism of the 35- to 48-kilodalton merozoite surface antigen (MSA-2) of the malaria parasite Plasmodium falciparum. Mol Cell Biol 1991; 11:963-71.
    • (1991) Mol Cell Biol , vol.11 , pp. 963-971
    • Fenton, B.1    Clark, J.T.2    Khan, C.M.3    Robinson, J.V.4    Walliker, D.5    Ridley, R.6
  • 143
    • 74949117436 scopus 로고
    • Characterisation of a novel merozoite membrane antigen of the human malaria parasite Plasmodium falciparum
    • Ramasamy R. Characterisation of a novel merozoite membrane antigen of the human malaria parasite Plasmodium falciparum. Immunol Cell Biol 1987; 1987:419-23.
    • (1987) Immunol Cell Biol 1987 , pp. 419-423
    • Ramasamy, R.1
  • 144
    • 0023851851 scopus 로고
    • An epitope recognised by inhibitory monoclonal antibodies that react with a 51 kilodalton merozoite surface antigen in Plasmodium falciparum
    • Epping RJ, Goldstone SD, Ingram LT, Upcroft JA, Ramasamy R, Cooper JA, et al. An epitope recognised by inhibitory monoclonal antibodies that react with a 51 kilodalton merozoite surface antigen in Plasmodium falciparum. Mol Biochem Parasitol 1988; 28:1-10.
    • (1988) Mol Biochem Parasitol , vol.28 , pp. 1-10
    • Epping, R.J.1    Goldstone, S.D.2    Ingram, L.T.3    Upcroft, J.A.4    Ramasamy, R.5    Cooper, J.A.6
  • 146
    • 64649083702 scopus 로고    scopus 로고
    • Evaluation of two long synthetic merozoite surface protein 2 peptides as malaria vaccine candidates
    • Flueck C, Frank G, Smith T, Jafarshad A, Nebie I, Sirima SB, et al. Evaluation of two long synthetic merozoite surface protein 2 peptides as malaria vaccine candidates. Vaccine 2009; 27:2653-61.
    • (2009) Vaccine , vol.27 , pp. 2653-2661
    • Flueck, C.1    Frank, G.2    Smith, T.3    Jafarshad, A.4    Nebie, I.5    Sirima, S.B.6
  • 147
    • 0028844321 scopus 로고
    • Human antibody response to Plasmodium falciparum merozoite surface protein 2 is serogroup specific and predominantly of the immunoglobulin G3 subclass
    • Taylor RR, Smith DB, Robinson VJ, McBride JS, Riley EM. Human antibody response to Plasmodium falciparum merozoite surface protein 2 is serogroup specific and predominantly of the immunoglobulin G3 subclass. Infect Immun 1995; 63:4382-8.
    • (1995) Infect Immun , vol.63 , pp. 4382-4388
    • Taylor, R.R.1    Smith, D.B.2    Robinson, V.J.3    McBride, J.S.4    Riley, E.M.5
  • 149
    • 0027987013 scopus 로고
    • Relationship between humoral response to Plasmodium falciparum merozoite surface antigen-2 and malaria morbidity in a highly endemic area of Papua New Guinea
    • al-Yaman F, Genton B, Anders RF, Falk M, Triglia T, Lewis D, et al. Relationship between humoral response to Plasmodium falciparum merozoite surface antigen-2 and malaria morbidity in a highly endemic area of Papua New Guinea. Am J Trop Med Hyg 1994; 51:593-602.
    • (1994) Am J Trop Med Hyg , vol.51 , pp. 593-602
    • al-Yaman, F.1    Genton, B.2    Anders, R.F.3    Falk, M.4    Triglia, T.5    Lewis, D.6
  • 150
    • 0347510966 scopus 로고    scopus 로고
    • Serum IgG3 to the Plasmodium falciparum merozoite surface protein 2 is strongly associated with a reduced prospective risk of malaria
    • Metzger WG, Okenu DM, Cavanagh DR, Robinson JV, Bojang KA, Weiss HA, et al. Serum IgG3 to the Plasmodium falciparum merozoite surface protein 2 is strongly associated with a reduced prospective risk of malaria. Parasite Immunol 2003; 25:307-12.
    • (2003) Parasite Immunol , vol.25 , pp. 307-312
    • Metzger, W.G.1    Okenu, D.M.2    Cavanagh, D.R.3    Robinson, J.V.4    Bojang, K.A.5    Weiss, H.A.6
  • 151
    • 33646144191 scopus 로고    scopus 로고
    • High levels of serum antibodies to merozoite surface protein 2 of Plasmodium falciparum are associated with reduced risk of clinical malaria in coastal Kenya
    • Polley SD, Conway DJ, Cavanagh DR, McBride JS, Lowe BS, Williams TN, et al. High levels of serum antibodies to merozoite surface protein 2 of Plasmodium falciparum are associated with reduced risk of clinical malaria in coastal Kenya. Vaccine 2006; 24:4233-46.
    • (2006) Vaccine , vol.24 , pp. 4233-4246
    • Polley, S.D.1    Conway, D.J.2    Cavanagh, D.R.3    McBride, J.S.4    Lowe, B.S.5    Williams, T.N.6
  • 153
    • 42749096469 scopus 로고    scopus 로고
    • Solution conformation, backbone dynamics and lipid interactions of the intrinsically unstructured malaria surface protein MSP2
    • Zhang X, Perugini MA, Yao S, Adda CG, Murphy VJ, Low A, et al. Solution conformation, backbone dynamics and lipid interactions of the intrinsically unstructured malaria surface protein MSP2. J Mol Biol 2008; 379:105-21.
    • (2008) J Mol Biol , vol.379 , pp. 105-121
    • Zhang, X.1    Perugini, M.A.2    Yao, S.3    Adda, C.G.4    Murphy, V.J.5    Low, A.6
  • 154
    • 33750711671 scopus 로고    scopus 로고
    • Abundance of intrinsically unstructured proteins in P. falciparum and other apicomplexan parasite proteomes
    • Feng ZP, Zhang X, Han P, Arora N, Anders RF, Norton RS. Abundance of intrinsically unstructured proteins in P. falciparum and other apicomplexan parasite proteomes. Mol Biochem Parasitol 2006; 150:256-67.
    • (2006) Mol Biochem Parasitol , vol.150 , pp. 256-267
    • Feng, Z.P.1    Zhang, X.2    Han, P.3    Arora, N.4    Anders, R.F.5    Norton, R.S.6
  • 156
    • 37349023138 scopus 로고    scopus 로고
    • A partially structured region of a largely unstructured protein, Plasmodium falciparum merozoite surface protein 2 (MSP2), forms amyloid-like fibrils
    • Yang X, Adda CG, Keizer DW, Murphy VJ, Rizkalla MM, Perugini MA, et al. A partially structured region of a largely unstructured protein, Plasmodium falciparum merozoite surface protein 2 (MSP2), forms amyloid-like fibrils. J Pept Sci 2007; 13:839-48.
    • (2007) J Pept Sci , vol.13 , pp. 839-848
    • Yang, X.1    Adda, C.G.2    Keizer, D.W.3    Murphy, V.J.4    Rizkalla, M.M.5    Perugini, M.A.6
  • 157
    • 34548644754 scopus 로고    scopus 로고
    • Merozoite surface protein 2 of Plasmodium falciparum: Expression, structure, dynamics and fibril formation of the conserved N-terminal domain
    • Low A, Chandrashekaran IR, Adda CG, Yao S, Sabo JK, Zhang X, et al. Merozoite surface protein 2 of Plasmodium falciparum: expression, structure, dynamics and fibril formation of the conserved N-terminal domain. Biopolymers 2007; 87:12-22.
    • (2007) Biopolymers , vol.87 , pp. 12-22
    • Low, A.1    Chandrashekaran, I.R.2    Adda, C.G.3    Yao, S.4    Sabo, J.K.5    Zhang, X.6
  • 158
    • 72449139985 scopus 로고    scopus 로고
    • Intrinsically Disordered Proteins and Their Environment: Effects of Strong Denaturants, Temperature, pH, Counter Ions, Membranes, Binding Partners, Osmolytes and Macromolecular Crowding
    • In press
    • Uversky VN. Intrinsically Disordered Proteins and Their Environment: Effects of Strong Denaturants, Temperature, pH, Counter Ions, Membranes, Binding Partners, Osmolytes and Macromolecular Crowding. Protein J 2009; In press.
    • (2009) Protein J
    • Uversky, V.N.1
  • 159
    • 14644435825 scopus 로고    scopus 로고
    • Intrinsically unstructured proteins and their functions
    • Dyson HJ, Wright PE. Intrinsically unstructured proteins and their functions. Nat Rev Mol Cell Biol 2005; 6:197-208.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 197-208
    • Dyson, H.J.1    Wright, P.E.2
  • 161
    • 68949126830 scopus 로고    scopus 로고
    • Genetic diversity and malaria vaccine design, testing and efficacy: Preventing and overcoming 'vaccine resistant malaria'
    • Takala SL, Plowe CV. Genetic diversity and malaria vaccine design, testing and efficacy: preventing and overcoming 'vaccine resistant malaria'. Parasite Immunol 2009; 31:560-73.
    • (2009) Parasite Immunol , vol.31 , pp. 560-573
    • Takala, S.L.1    Plowe, C.V.2
  • 162
    • 55049114441 scopus 로고    scopus 로고
    • Mixed allele malaria vaccines: Host protection and withinhost selection
    • Barclay VC, Chan BH, Anders RF, Read AF. Mixed allele malaria vaccines: host protection and withinhost selection. Vaccine 2008; 26:6099-107.
    • (2008) Vaccine , vol.26 , pp. 6099-6107
    • Barclay, V.C.1    Chan, B.H.2    Anders, R.F.3    Read, A.F.4
  • 163
    • 45549091822 scopus 로고    scopus 로고
    • Population structure of the genes encoding the polymorphic Plasmodium falciparum apical membrane antigen 1: Implications for vaccine design
    • Duan J, Mu J, Thera MA, Joy D, Kosakovsky Pond SL, Diemert D, et al. Population structure of the genes encoding the polymorphic Plasmodium falciparum apical membrane antigen 1: implications for vaccine design. Proc Natl Acad Sci USA 2008; 105:7857-62.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 7857-7862
    • Duan, J.1    Mu, J.2    Thera, M.A.3    Joy, D.4    Kosakovsky Pond, S.L.5    Diemert, D.6
  • 164
    • 46249103583 scopus 로고    scopus 로고
    • A diversity-covering approach to immunization with Plasmodium falciparum apical membrane antigen 1 induces broader allelic recognition and growth inhibition responses in rabbits
    • Remarque EJ, Faber BW, Kocken CH, Thomas AW. A diversity-covering approach to immunization with Plasmodium falciparum apical membrane antigen 1 induces broader allelic recognition and growth inhibition responses in rabbits. Infect Immun 2008; 76:2660-70.
    • (2008) Infect Immun , vol.76 , pp. 2660-2670
    • Remarque, E.J.1    Faber, B.W.2    Kocken, C.H.3    Thomas, A.W.4
  • 165
    • 36749029317 scopus 로고    scopus 로고
    • Malaria vaccine-related benefits of a single protein comprising Plasmodium falciparum apical membrane antigen 1 domains I and II fused to a modified form of the 19-kilodalton C-terminal fragment of merozoite surface protein 1
    • Faber BW, Remarque EJ, Morgan WD, Kocken CH, Holder AA, Thomas AW. Malaria vaccine-related benefits of a single protein comprising Plasmodium falciparum apical membrane antigen 1 domains I and II fused to a modified form of the 19-kilodalton C-terminal fragment of merozoite surface protein 1. Infect Immun 2007; 75:5947-55.
    • (2007) Infect Immun , vol.75 , pp. 5947-5955
    • Faber, B.W.1    Remarque, E.J.2    Morgan, W.D.3    Kocken, C.H.4    Holder, A.A.5    Thomas, A.W.6


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