IgG3 antibodies to Plasmodium falciparum merozoite surface protein 2(MSP2): Increasing prevalence with age and association with clinical immunity to malaria

American Journal of Tropical Medicine and Hygiene

Volumn 58, Issue 4, 1998, Pages 406-413

  Taylor, Rachel R ^a   Allen, Stephen J ^b   Greenwood, Brian M ^c   Riley, Eleanor M ^d  

^a University of Oxford ^*  (France)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ANTIBODY; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN G3 ANTIBODY; IMMUNOGLOBULIN G4; MALARIA VACCINE; MEROZOITE SURFACE PROTEIN 2; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ANTIBODY DETECTION; ANTIBODY SPECIFICITY; ARTICLE; CHILD; CONTROLLED STUDY; DISEASE TRANSMISSION; GENETIC SUSCEPTIBILITY; HEALTH SURVEY; HUMAN; HUMAN CELL; HUMAN TISSUE; INFECTION RISK; MAJOR CLINICAL STUDY; MALARIA; MEROZOITE; PLASMODIUM FALCIPARUM; PREVALENCE; SERODIAGNOSIS;

EID: 0031895495     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.1998.58.406     Document Type: Article

References (34)

1. Greenwood BM, Bradley AK, Greenwood AM, Byass P, Jammeh K, Marsh K, Tulloch S, Oldfield FSJ, Hayes R, 1987. Mortality and morbidity from malaria among children in a rural area of The Gambia. West Africa. Trans R Soc Trop Med Hyg 81: 478-486.
2. Day K, Marsh K, 1991. Naturally acquired immunity to Plasmodium falciparum. Parasitol Today 7: 68-71.
3. Good MF, Miller LH, Kumar S, Quakyi IA, Keister D, Adams JH, Moss B, Berzofsky JA, Carter R, 1988. Limited immunological recognition of critical malaria vaccine candidate antigens. Science 242: 574-577.
4. Baird JK, 1995. Host age as a determinant of naturally acquired immunity to Plasmodium falciparum. Parasitol Today 11: 105-111.
5. Druilhe P, Khusmith S, 1987. Epidemiological correlation between levels of antibodies promoting merozoite phagocytosis of Plasmodium falciparum and malaria immune status. Infect Immun 55: 888-891.
6. Groux H, Gysin J, 1990. Opsonisation as an effector mechanism in human protection against asexual blood stages of Plasmodium falciparum: functional role of IgG subclasses. Res Immunol 141: 529-542.
7. Bouharoun-Tayoun H, Attanath P, Sabchareon A, Chongsuphajaisiddhi T, Druilhe P, 1990. Antibodies that protect humans against Plasmodium falciparum blood stages do not on their own inhibit parasite growth and invasion in vitro but act in co-operation with monocytes. J Exp Med 172: 1633-1641.
8. Bouharoun-Tayoun H, Druilhe P, 1992. Plasmodium falciparum malaria: evidence for an isotype imbalance which may be responsible for delayed acquisition of protective immunity. Infect Immun 60: 1473-1481.
9. Smythe JA, Coppel RL, Brown GV, Ramasamy R, Kemp DJ, Anders RF. 1988. Identification of two integral membrane proteins of Plasmodium falciparum. Proc Natl Acad Sci USA 85: 5195-5199.
10. Smythe JA, Peterson GM, Coppel R, Saul AJ, Kemp DJ, Anders R, 1990. Structural diversity in the 45-kilodalton merozoite surface antigen of Plasmodium falciparum. Mol Biochem Parasitol 39: 227-234.
11. Thomas AW, Carr DA, Carter JM, Lyon JA, 1990. Sequence comparison of allelic forms of the Plasmodium falciparum merozoite surface antigen MSA2. Mol Biochem Parasitol 43: 211-220.
12. Taylor RR, Smith DB, Robinson VJ, McBride JS, Riley EM, 1995. Human antibody response to Plasmodium falciparum merozoite surface protein 2 is serogroup specific and predominantly of the IgG3 subclass. Infect Immun 63: 4382-4388.
13. Rzepczyk CM, Hale K, Woodroffe N, Bobogare A, Csurhes P, Ishii A, Ferrante A, 1997. Humoral immune responses of Solomon Islanders to the merozoite surface antigen 2 of Plasmodium falciparum show pronounced skewing towards antibodies of the immunoglobulin G3 subclass. Infect Immun 65: 1098-1100.
14. Clark JT, Donachie S, Anand R, Wilson CF, Heidrich H, McBride JS, 1989. 46-53 kilodalton glycoprotein from the surface of Plasmodium falciparum merozoites. Mol Biochem Parasitol 32: 15-24.
15. Ramasamy R, Jones GL, Lord R, 1990.Characterisation of an inhibitory monoclonal antibody-defined epitope on a malarial vaccine candidate antigen. Immunol Lett 23: 305-310.
16. Saul A, Lord R, Jones GL, Spencer L, 1992. Protective immunisation with invariant peptides of the Plasmodium falciparum antigen MSA2. J Immunol 148: 208-211.
17. Pye D, Edwards SJ, Anders RF, O'Brien CM, Franchina P, Corcoran LN, Monger C, Peterson MG, Vandenberg KL, Smythe JA, Weatley SR. Coppel RL, Webster TL, Kemp DJ, Hampson AW, Langford CJ, 1991. Failure of recombinant vaccinia viruses expressing Plasmodium falciparum antigens to protect Saimiri monkeys against malaria. Infect Immun 59: 2403-2411.
18. Al-Yaman F, Genton B, Anders RF, Falk M, Triglia T, Lewis D, Hii J, Beck H, Alpers MP, 1994. Relationship between humoral response to Plasmodium falciparum merozoite surface antigen-2 and malaria morbidity in a highly endemic area of Papua New Guinea. Am J Trop Med Hyg 51: 593-602.
19. Riley EM, Allen SJ, Bennett S, Thomas PJ, Andersson G, O'Donnell A, Lindsay SW, Good MF, Greenwood BM, 1990. Recognition of dominant T cell stimulating epitopes from the circumsporozoite protein of Plasmodium falciparum and relationship to malaria morbidity in Gambian children. Trans R Soc Trop Med Hyg 84: 648-657.
20. Riley EM, Allen SJ, Wheeler J, Blackman MJ, Bennett S, Takacs B, Shönfeld H, Holder AA, Greenwood BM, 1992. Naturally acquired cellular and humoral immune responses to the major merozoite surface antigen of Plasmodium falciparum are associated with reduced malaria morbidity. Parasite Immunol 14: 321-338.
21. Dziegiel M, Rowe P, Bennett S, Allen SJ, Olerup O, Gottschau A, Riley EM, 1993. IgM and IgG antibody responses to Plasmodium falciparum glutamate rich protein: correlation with clinical immunity in Gambian children. Infect Immun 61: 103-108.
22. Al-Yaman F, Genton B, Anders R, Taraika J, Ginny M, Mellor S, Alpers MP, 1995. Assessment of the role of the humoral response to Plasmodium falciparum MSP2 compared to RESA and SPf66 in protecting Papua New Guinean children from clinical malaria. Parasite Immunol 17: 493-501.
23. 19, the carboxy-terminal fragment of the major merozoite surface protein of Plasmodium falciparum. Infect Immun 63: 456-466.
24. Ya PS, Sayed U, Qari SH, Roberts JM, Udhayakumar V, Oloo AJ, Hawley W, Kaslow DC, Nahlen BL, Lal AA, 1996. Natural immune response to the C-terminal 19-kilodalton domain of Plasmodium falciparum merozoite surface protein 1. Infect Immun 64: 2716-2723.
25. Beck H, Felger I, Genton B, Alexander N, Al-Yaman F, Anders RF, Alpers M, 1995. Humoral and cell-mediated immunity to the Plasmodium falciparum ring-infected erythrocyte surface antigen in an adult population exposed to highly endemic malaria. Infect Immun 63: 596-600.
26. Aribot G, Rogier C, Sarthou J, Trape J, Toure-Balde A, Druilhe P, Roussilhon C, 1996. Pattern of immunoglobulin isotype response to Plasmodium falciparum blood-stage antigens in individuals living in a holoendemic area of Senegal (Dielmo, West Africa). Am J Trop Med Hyg 54: 449-457.
27. Goldblatt D, Turner MW, Levinsky RJ, 1990. Branhamella cattarhalis: Antigenic determinants and the development of the IgG subclass response in childhood. J Infect Dis 162: 1128-1135.
28. Lee SI, Heiner DC, Wara D, 1986. Development of serum IgG subclass levels in children. Monogr Allergy 19: 113-117.
29. Snapper CM, Monod JJ, 1993. Towards a comprehensive view of immunoglobulin class switching. Immunol Today 14: 15-17.
30. Egan AF, Morris J, Barnish G, Allen S, Greenwood BM, Kaslow DC, Holder AA, Riley EM, 1996. Clinical immunity to Plasmodium falciparum malaria is associated with serum antibodies to the 19kDa C-terminal fragment of the merozoite surface antigen, PfMSP1. J Infect Dis 173: 765-769.
31. Van den Winkel JGJ, Capel PJA, 1993. Human IgG Fc receptor heterogeneity: molecular aspects and clinical implications. Immunol Today 14: 215-221.
32. Spiegelberg HL, 1974. Biological activities of immunoglobulins of different classes and subclasses. Adv Immunol 19: 259-295.
33. Ferrante A, Rzepczyk CM, 1997. Atypical IgG subclass antibody responses to Plasmodium falciparum asexual stage antigens. Parasitol Today 13: 145-148.
34. Taylor RR, Egan A, McGuinness D, Jepson A, Adair R, Drakely C, Riley E, 1996. Selective recognition of malaria antigens by human serum antibodies is not genetically determined but demonstrates some features of clonal imprinting. Int Immunol 8: 905-915.